TLR10 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description toll-like receptor 10|The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010] (NCBI Entrez Gene Database, 81793)
External Link https://ncbi.nlm.nih.gov/gene/81793
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Genes

498 genes differentially expressed following the TLR10 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SFRP1 secreted frizzled-related protein 1 0.0168171
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0166019
PUF60 poly-U binding splicing factor 60KDa 0.0156474
CA2 carbonic anhydrase II 0.0142941
XIC X chromosome inactivation center 0.0133015
MT1H metallothionein 1H 0.0120695
MT2A metallothionein 2A 0.0120115
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0119734
GBP1 guanylate binding protein 1, interferon-inducible 0.0118696
PLAT plasminogen activator, tissue 0.0118394
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.0117216
CALML5 calmodulin-like 5 0.0115878
MT1HL1 metallothionein 1H-like 1 0.01147
MT1X metallothionein 1X 0.0114202
MT1G metallothionein 1G 0.0113803
JMJD6 jumonji domain containing 6 0.0113576
RGS1 regulator of G-protein signaling 1 0.0110611
GPM6B glycoprotein M6B 0.0108227
MT1F metallothionein 1F 0.0107667
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.0104961
ADGRL2 adhesion G protein-coupled receptor L2 0.0104469
TYRP1 tyrosinase-related protein 1 0.0102042
MT1E metallothionein 1E 0.0100992
CXCL12 chemokine (C-X-C motif) ligand 12 0.0100555
CXCL10 chemokine (C-X-C motif) ligand 10 0.0100468
MAGEA3 melanoma antigen family A3 0.0100377
QKI QKI, KH domain containing, RNA binding 0.00988705
PDZD2 PDZ domain containing 2 0.00981885
PDE4B phosphodiesterase 4B, cAMP-specific 0.00960521
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00947313
EGR3 early growth response 3 0.00943764
CTNND1 catenin (cadherin-associated protein), delta 1 0.00943622
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.00926274
ANOS1 anosmin 1 0.00925078
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0092235
CLC Charcot-Leyden crystal galectin 0.00922133
TACSTD2 tumor-associated calcium signal transducer 2 0.00921258
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00918346
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00916056
NES nestin 0.00914506
KLK8 kallikrein-related peptidase 8 0.00911616
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00874535
FZD6 frizzled class receptor 6 0.00867155
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00861814
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00853766
SYNM synemin, intermediate filament protein 0.00848515
SRGN serglycin 0.00846312
RUNX3 runt-related transcription factor 3 0.00844186
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00843219
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00842812
TNIK TRAF2 and NCK interacting kinase 0.00837873
ABLIM1 actin binding LIM protein 1 0.00836023
PDZK1IP1 PDZK1 interacting protein 1 0.00834788
KLK7 kallikrein-related peptidase 7 0.00827777
IRS2 insulin receptor substrate 2 0.00826959
ZDHHC6 zinc finger, DHHC-type containing 6 0.00823231
ANXA3 annexin A3 0.00822059
SLC43A3 solute carrier family 43, member 3 0.00809601
CD36 CD36 molecule (thrombospondin receptor) 0.00808979
KRT7 keratin 7, type II 0.00807481
KRT14 keratin 14, type I 0.00806179
CTSG cathepsin G 0.00797387
MEIS2 Meis homeobox 2 0.00797133
ZNF185 zinc finger protein 185 (LIM domain) 0.00792874
JCHAIN joining chain of multimeric IgA and IgM 0.00785582
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00777953
LAPTM4B lysosomal protein transmembrane 4 beta 0.00774258
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00773445
PRSS21 protease, serine, 21 (testisin) 0.00770729
PDZRN3 PDZ domain containing ring finger 3 0.00767717
GPR171 G protein-coupled receptor 171 0.00766393
KRT1 keratin 1, type II 0.00758548
BCHE butyrylcholinesterase 0.00756782
PLP1 proteolipid protein 1 0.00756723
CXCL9 chemokine (C-X-C motif) ligand 9 0.00755926
TNS1 tensin 1 0.00754425
SCRIB scribbled planar cell polarity protein 0.00749087
TICAM1 toll-like receptor adaptor molecule 1 0.00747945
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00744874
ACTN1 actinin, alpha 1 0.00740676
PMEL premelanosome protein 0.00740648
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00738658
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00737997
MXI1 MAX interactor 1, dimerization protein 0.00736722
DMD dystrophin 0.00736628
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00735231
RNF167 ring finger protein 167 0.0073349
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00731064
NFIB nuclear factor I/B 0.00731046
NID1 nidogen 1 0.00727752
NAV2 neuron navigator 2 0.00725967
FOSL2 FOS-like antigen 2 0.00722742
SMC1A structural maintenance of chromosomes 1A 0.00722676
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0072123
BHLHE41 basic helix-loop-helix family, member e41 0.00720264
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0072001
ARG1 arginase 1 0.00718823
PBX1 pre-B-cell leukemia homeobox 1 0.00718088
TLE4 transducin-like enhancer of split 4 0.00715849
PRKCA protein kinase C, alpha 0.00709999
TKTL1 transketolase-like 1 0.00707012
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00702649
PLAGL1 pleiomorphic adenoma gene-like 1 0.00700745
GPR183 G protein-coupled receptor 183 0.00696647
GIMAP4 GTPase, IMAP family member 4 0.00695988
PRKD1 protein kinase D1 0.00695021
MSLN mesothelin 0.00691741
PITX3 paired-like homeodomain 3 0.00689651
LY75 lymphocyte antigen 75 0.00685757
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.00683902
PCGF2 polycomb group ring finger 2 0.00681067
CD53 CD53 molecule 0.00678969
AKAP11 A kinase (PRKA) anchor protein 11 0.00678731
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00676229
CALML3 calmodulin-like 3 0.00675763
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00674545
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00674108
BCL2A1 BCL2-related protein A1 0.00673015
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00669829
MIA melanoma inhibitory activity 0.00668681
MLH1 mutL homolog 1 0.0066637
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00666312
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00665998
PER3 period circadian clock 3 0.0066571
LOR loricrin 0.00665635
GALC galactosylceramidase 0.00663908
CCR7 chemokine (C-C motif) receptor 7 0.00662686
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.00662511
XPO7 exportin 7 0.00658552
PBX3 pre-B-cell leukemia homeobox 3 0.00658538
IDE insulin-degrading enzyme 0.00656406
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00655373
SRPX sushi-repeat containing protein, X-linked 0.00654508
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00653344
FCGBP Fc fragment of IgG binding protein 0.00653169
MYO1C myosin IC 0.00649095
AHCYL1 adenosylhomocysteinase-like 1 0.00646829
TOX thymocyte selection-associated high mobility group box 0.00646299
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00645177
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00642807
KLK5 kallikrein-related peptidase 5 0.00642562
FGFR1 fibroblast growth factor receptor 1 0.00641419
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.00641173
MLANA melan-A 0.00641108
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00640207
ADGRG6 adhesion G protein-coupled receptor G6 0.00639859
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00639086
ANO10 anoctamin 10 0.00638411
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00637324
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.0063691
SLPI secretory leukocyte peptidase inhibitor 0.00636014
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00635306
PNMA2 paraneoplastic Ma antigen 2 0.00633848
TYR tyrosinase 0.00632838
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00632333
AKAP12 A kinase (PRKA) anchor protein 12 0.0063032
SELL selectin L 0.00626513
EDNRB endothelin receptor type B 0.00626049
FKBP4 FK506 binding protein 4, 59kDa 0.00625499
CD93 CD93 molecule 0.00624946
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00623189
ALCAM activated leukocyte cell adhesion molecule 0.00619339
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00619248
CHD7 chromodomain helicase DNA binding protein 7 0.00619155
CXCL13 chemokine (C-X-C motif) ligand 13 0.0061906
DKC1 dyskeratosis congenita 1, dyskerin 0.00618541
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.00616812
SST somatostatin 0.00616283
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.00613806
EGR2 early growth response 2 0.00613269
IFI27 interferon, alpha-inducible protein 27 0.00611788
NIBAN1 niban apoptosis regulator 1 0.00611112
FABP4 fatty acid binding protein 4, adipocyte 0.00608742
THBD thrombomodulin 0.00607975
AHSP alpha hemoglobin stabilizing protein 0.00607369
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00606262
ARMCX2 armadillo repeat containing, X-linked 2 0.0060466
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.00603972
LY6D lymphocyte antigen 6 complex, locus D 0.00603239
RAB38 RAB38, member RAS oncogene family 0.00603011
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00594426
HK1 hexokinase 1 0.00594282
JAM2 junctional adhesion molecule 2 0.0059426
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00592002
HHEX hematopoietically expressed homeobox 0.00591082
EDN3 endothelin 3 0.00590587
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.00589915
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00583555
AK4 adenylate kinase 4 0.00581278
EHBP1 EH domain binding protein 1 0.0057978
WWTR1 WW domain containing transcription regulator 1 0.00579018
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00578694
DCHS1 dachsous cadherin-related 1 0.00578265
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00578052
CYBRD1 cytochrome b reductase 1 0.00577392
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00576703
MTMR11 myotubularin related protein 11 0.00576703
GYPC glycophorin C (Gerbich blood group) 0.00574701
KLK6 kallikrein-related peptidase 6 0.00573443
IRF8 interferon regulatory factor 8 0.00572505
CAV2 caveolin 2 0.00572368
CADM1 cell adhesion molecule 1 0.00569929
DSG1 desmoglein 1 0.00569252
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00568319
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.005662
CH25H cholesterol 25-hydroxylase 0.00566085
PEG10 paternally expressed 10 0.00565623
GPR65 G protein-coupled receptor 65 0.00565295
OXTR oxytocin receptor 0.00564123
BIRC3 baculoviral IAP repeat containing 3 0.00562164
TMEM45A transmembrane protein 45A 0.00561997
PLEK pleckstrin 0.00561241
AQP1 aquaporin 1 (Colton blood group) 0.00560576
IL15 interleukin 15 0.00558005
RNASE3 ribonuclease, RNase A family, 3 0.00557877
TRAF1 TNF receptor-associated factor 1 0.00555649
MGLL monoglyceride lipase 0.00555154
CD70 CD70 molecule 0.00551136
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00549255
LYST lysosomal trafficking regulator 0.0054847
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00548153
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00546292
KYAT3 kynurenine aminotransferase 3 0.00545902
GJA1 gap junction protein, alpha 1, 43kDa 0.00545363
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.0054527
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00544671
PPIF peptidylprolyl isomerase F 0.0054332
VWA8 von Willebrand factor A domain containing 8 0.00541263
EXOSC4 exosome component 4 0.00541236
WLS wntless Wnt ligand secretion mediator 0.00540083
WNT5A wingless-type MMTV integration site family, member 5A 0.00539602
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00539526
VIM vimentin 0.00538778
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00538464
SLURP1 secreted LY6/PLAUR domain containing 1 0.00537692
TAL1 T-cell acute lymphocytic leukemia 1 0.00537644
DSC1 desmocollin 1 0.00537553
NCAM1 neural cell adhesion molecule 1 0.00535588
FMO1 flavin containing monooxygenase 1 0.00535173
MAGEA12 melanoma antigen family A12 0.00534882
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00533039
CXCL11 chemokine (C-X-C motif) ligand 11 0.00532798
DCT dopachrome tautomerase 0.00532583
EREG epiregulin 0.00532521
SARS1 seryl-tRNA synthetase 1 0.00531865
BST2 bone marrow stromal cell antigen 2 0.00531777
MSN moesin 0.00531555
IL32 interleukin 32 0.00531537
ORC1 origin recognition complex, subunit 1 0.0053115

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.020294
MAP7 microtubule-associated protein 7 -0.0185512
KRT19 keratin 19, type I -0.0175949
PERP PERP, TP53 apoptosis effector -0.0144956
SYT1 synaptotagmin I -0.0139136
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.0135627
TPSAB1 tryptase alpha/beta 1 -0.0129421
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0126089
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0124875
AKR1C2 aldo-keto reductase family 1, member C2 -0.0115889
CD9 CD9 molecule -0.0115382
AKR1C1 aldo-keto reductase family 1, member C1 -0.0113868
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0109776
IPO13 importin 13 -0.0104477
GLUL glutamate-ammonia ligase -0.00997042
COMP cartilage oligomeric matrix protein -0.00982652
AKR1C3 aldo-keto reductase family 1, member C3 -0.00979658
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00972177
HOXC6 homeobox C6 -0.0096699
TXNIP thioredoxin interacting protein -0.0096684
BTG1 B-cell translocation gene 1, anti-proliferative -0.00964341
MGP matrix Gla protein -0.00958041
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00941458
ANXA4 annexin A4 -0.00936381
AEBP1 AE binding protein 1 -0.00929961
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00916688
KDM5D lysine (K)-specific demethylase 5D -0.00914641
S100A10 S100 calcium binding protein A10 -0.0090403
BRD2 bromodomain containing 2 -0.00884663
CTSZ cathepsin Z -0.00879817
COL6A3 collagen, type VI, alpha 3 -0.00876484
SFRP4 secreted frizzled-related protein 4 -0.00869845
CD99 CD99 molecule -0.00867907
SIRT3 sirtuin 3 -0.00862461
CP ceruloplasmin (ferroxidase) -0.00859717
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00857804
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00839911
ZNF721 zinc finger protein 721 -0.00835872
SDC2 syndecan 2 -0.00835073
AGR2 anterior gradient 2 -0.00833288
GUSBP3 glucuronidase, beta pseudogene 3 -0.00833205
APOD apolipoprotein D -0.00829968
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00827597
CEMIP cell migration inducing protein, hyaluronan binding -0.00825847
TOX3 TOX high mobility group box family member 3 -0.00808671
TSPAN1 tetraspanin 1 -0.00806568
STK26 serine/threonine protein kinase 26 -0.00806145
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00799424
CEL carboxyl ester lipase -0.00798456
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00797011
IGFBP6 insulin-like growth factor binding protein 6 -0.00795766
YBX3 Y box binding protein 3 -0.00795052
S100A8 S100 calcium binding protein A8 -0.00792971
TAGLN transgelin -0.00786756
AMACR alpha-methylacyl-CoA racemase -0.00780449
INHBA inhibin, beta A -0.00778182
HOXC10 homeobox C10 -0.00777144
NUTF2 nuclear transport factor 2 -0.00774061
DUSP1 dual specificity phosphatase 1 -0.0076952
ABHD2 abhydrolase domain containing 2 -0.00765038
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.00762177
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00761607
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00760461
PTK2B protein tyrosine kinase 2 beta -0.00760107
CYBA cytochrome b-245, alpha polypeptide -0.0074118
NUSAP1 nucleolar and spindle associated protein 1 -0.00739407
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00736405
GRK2 G protein-coupled receptor kinase 2 -0.00734161
CLEC3B C-type lectin domain family 3, member B -0.00732798
HTRA1 HtrA serine peptidase 1 -0.00729855
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00728957
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00723828
IFI6 interferon, alpha-inducible protein 6 -0.00722522
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00721612
CERT1 ceramide transporter 1 -0.00716923
LEFTY1 left-right determination factor 1 -0.00716811
LITAF lipopolysaccharide-induced TNF factor -0.00714093
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00711653
ELN elastin -0.00707967
HSPA8 heat shock 70kDa protein 8 -0.00706881
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00705468
ZNF160 zinc finger protein 160 -0.00699069
HEBP2 heme binding protein 2 -0.00692421
TLE5 TLE family member 5, transcriptional modulator -0.00686957
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -0.00686264
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0068439
CRYM crystallin, mu -0.00683293
AKIRIN1 akirin 1 -0.00683158
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00682448
ASS1 argininosuccinate synthase 1 -0.00681393
MYH11 myosin, heavy chain 11, smooth muscle -0.00680794
KRT18 keratin 18, type I -0.00677825
ADM adrenomedullin -0.00677594
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00676616
LAMB1 laminin, beta 1 -0.00676329
FXYD2 FXYD domain containing ion transport regulator 2 -0.00671684
COL2A1 collagen, type II, alpha 1 -0.00667657
FGFR3 fibroblast growth factor receptor 3 -0.00664809
CST1 cystatin SN -0.00663808
STK39 serine threonine kinase 39 -0.00663719
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00657038
CUX1 cut-like homeobox 1 -0.00655969
AOC1 amine oxidase, copper containing 1 -0.00652711
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0065014
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -0.00648875
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00647822
ING3 inhibitor of growth family, member 3 -0.00646985
HSPA1A heat shock 70kDa protein 1A -0.00646543
BPIFA1 BPI fold containing family A, member 1 -0.00645992
SCAF11 SR-related CTD-associated factor 11 -0.00645594
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -0.00644015
APOA2 apolipoprotein A-II -0.00641573
ASPN asporin -0.00640596
CGA glycoprotein hormones, alpha polypeptide -0.00640454
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00638865
SEPP1 selenoprotein P, plasma, 1 -0.00638275
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00637647
SLC38A1 solute carrier family 38, member 1 -0.0063746
ADCY1 adenylate cyclase 1 (brain) -0.00637044
HAUS2 HAUS augmin-like complex, subunit 2 -0.00634867
THBS2 thrombospondin 2 -0.00631202
ZNF652 zinc finger protein 652 -0.00626506
CTSK cathepsin K -0.0062604
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -0.00625501
S100A9 S100 calcium binding protein A9 -0.00620938
IGFBP1 insulin-like growth factor binding protein 1 -0.00619377
SLC44A4 solute carrier family 44, member 4 -0.00617303
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00615638
IFITM2 interferon induced transmembrane protein 2 -0.00615602
NOTCH2NL notch 2 N-terminal like -0.00615499
CCN2 cellular communication network factor 2 -0.00614074
DEF8 differentially expressed in FDCP 8 homolog (mouse) -0.00613557
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00612067
PRR11 proline rich 11 -0.00611922
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00609174
AK1 adenylate kinase 1 -0.0060869
CLDN3 claudin 3 -0.00608286
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -0.00606744
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00606476
SV2B synaptic vesicle glycoprotein 2B -0.00603928
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -0.00603385
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -0.00601172
ZNF124 zinc finger protein 124 -0.0060117
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -0.00597444
LYN LYN proto-oncogene, Src family tyrosine kinase -0.005957
ANKRD36 ankyrin repeat domain 36 -0.00595493
HP haptoglobin -0.00595135
AKAP7 A kinase (PRKA) anchor protein 7 -0.00593601
TSPO translocator protein (18kDa) -0.00592107
FBXW12 F-box and WD repeat domain containing 12 -0.005919
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00591698
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00591339
LDHA lactate dehydrogenase A -0.00590861
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00590857
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.0059008
OSR2 odd-skipped related transciption factor 2 -0.0058849
HSPB8 heat shock 22kDa protein 8 -0.00588363
TRAPPC6A trafficking protein particle complex 6A -0.00587742
CST3 cystatin C -0.00586251
CD52 CD52 molecule -0.00584739
ANGPT1 angiopoietin 1 -0.0058447
S100A11 S100 calcium binding protein A11 -0.00582298
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00581851
PRKCZ protein kinase C, zeta -0.00579997
OLFM1 olfactomedin 1 -0.00579123
PCOLCE procollagen C-endopeptidase enhancer -0.0057866
VIL1 villin 1 -0.00578636
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -0.00578607
TYMS thymidylate synthetase -0.00576859
HMGB3 high mobility group box 3 -0.00576086
ZNF665 zinc finger protein 665 -0.00574378
EXPH5 exophilin 5 -0.00574035
DSP desmoplakin -0.00570775
SCGB2A1 secretoglobin, family 2A, member 1 -0.0057015
NDRG1 N-myc downstream regulated 1 -0.00569458
GPNMB glycoprotein (transmembrane) nmb -0.00569326
CCNA2 cyclin A2 -0.00567392
WASL Wiskott-Aldrich syndrome-like -0.00567348
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -0.00564034
FST follistatin -0.00562656
NKX3-1 NK3 homeobox 1 -0.00560175
NBPF10 neuroblastoma breakpoint family, member 10 -0.00560162
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa -0.00559838
PHACTR2 phosphatase and actin regulator 2 -0.0055832
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.00558178
ZNF611 zinc finger protein 611 -0.00554697
CCDC69 coiled-coil domain containing 69 -0.00554472
FBLN1 fibulin 1 -0.00554034
SERINC5 serine incorporator 5 -0.00553537
COL10A1 collagen, type X, alpha 1 -0.00553205
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00552259
TGFBI transforming growth factor, beta-induced, 68kDa -0.00551748
MB myoglobin -0.00550025
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00549246
NOTCH1 notch 1 -0.00548369
TMSB15A thymosin beta 15a -0.00547651
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -0.00545216
RAB14 RAB14, member RAS oncogene family -0.00544683
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -0.0054245
ABHD3 abhydrolase domain containing 3 -0.00542279
C4BPA complement component 4 binding protein, alpha -0.0053928
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -0.00536707
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -0.00536094
VSNL1 visinin-like 1 -0.00534307
TCF4 transcription factor 4 -0.00533243
TMEM41B transmembrane protein 41B -0.00531934
SPATA20 spermatogenesis associated 20 -0.00531331
HMGN3 high mobility group nucleosomal binding domain 3 -0.0053115
GSE1 Gse1 coiled-coil protein -0.00530859
FN1 fibronectin 1 -0.00530627
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00530405
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00530163
MXD4 MAX dimerization protein 4 -0.00528103
ZBTB38 zinc finger and BTB domain containing 38 -0.00527197
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -0.00526701
IGFBP5 insulin-like growth factor binding protein 5 -0.00526403
AHSG alpha-2-HS-glycoprotein -0.00526138
CASP6 caspase 6, apoptosis-related cysteine peptidase -0.00526008
PSD3 pleckstrin and Sec7 domain containing 3 -0.00524442
DAPK1 death-associated protein kinase 1 -0.00524352
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.00521798
PCLAF PCNA clamp associated factor -0.0052138
PIGR polymeric immunoglobulin receptor -0.00520784
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.00520743
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.00520722
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00519791
CYB5A cytochrome b5 type A (microsomal) -0.00519526
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0051767
ADGRG2 adhesion G protein-coupled receptor G2 -0.00515354
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00514637
IFT20 intraflagellar transport 20 -0.00514288
TGIF1 TGFB-induced factor homeobox 1 -0.00513304
ACAN aggrecan -0.00512724
XYLT1 xylosyltransferase I -0.00512448
CPA3 carboxypeptidase A3 (mast cell) -0.00512093
IFITM3 interferon induced transmembrane protein 3 -0.0051175
UFD1 ubiquitin recognition factor in ER associated degradation 1 -0.00511438
ZNF165 zinc finger protein 165 -0.00511045
COL1A1 collagen, type I, alpha 1 -0.00510626
GLRX glutaredoxin (thioltransferase) -0.00508728
CLDN4 claudin 4 -0.00508305
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0050667
CHIC2 cysteine-rich hydrophobic domain 2 -0.00506022
RWDD1 RWD domain containing 1 -0.00505883
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00505421
EPCAM epithelial cell adhesion molecule -0.0050451
SSBP1 single-stranded DNA binding protein 1, mitochondrial -0.00503058
CCNG2 cyclin G2 -0.00502394
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00501975