TLR4 signaling and tolerance Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP3851.html
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Genes

28 proteins participating in the TLR4 signaling and tolerance pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
CHUK conserved helix-loop-helix ubiquitous kinase
CXCL8 chemokine (C-X-C motif) ligand 8
IFNB1 interferon, beta 1, fibroblast
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL6 interleukin 6
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TBK1 TANK-binding kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAM1 translocation associated membrane protein 1