| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | toll-like receptor 5|This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009] (NCBI Entrez Gene Database, 7100) |
| External Link | https://ncbi.nlm.nih.gov/gene/7100 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the TLR5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC38A1 | solute carrier family 38, member 1 | 0.0114948 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0114898 |
| ADM | adrenomedullin | 0.0111037 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0106411 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.0100296 |
| AUTS2 | autism susceptibility candidate 2 | 0.00993547 |
| RBM34 | RNA binding motif protein 34 | 0.00958261 |
| S100A2 | S100 calcium binding protein A2 | 0.00941771 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00928881 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00905699 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00905219 |
| FABP7 | fatty acid binding protein 7, brain | 0.00896254 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00893142 |
| SNX7 | sorting nexin 7 | 0.00883665 |
| SLN | sarcolipin | 0.00861904 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00842959 |
| STAP2 | signal transducing adaptor family member 2 | 0.00840175 |
| IL32 | interleukin 32 | 0.00833979 |
| FABP1 | fatty acid binding protein 1, liver | 0.00826712 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00819783 |
| TTN | titin | 0.00805932 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00804177 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00801414 |
| KRT81 | keratin 81, type II | 0.00798964 |
| TOX | thymocyte selection-associated high mobility group box | 0.00795295 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00789363 |
| ABLIM1 | actin binding LIM protein 1 | 0.00786284 |
| NDRG1 | N-myc downstream regulated 1 | 0.00778957 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00766323 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00762722 |
| KRT23 | keratin 23, type I | 0.00748663 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00748034 |
| RGS13 | regulator of G-protein signaling 13 | 0.00743629 |
| CA2 | carbonic anhydrase II | 0.00741407 |
| SPRR3 | small proline-rich protein 3 | 0.00725929 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00718054 |
| GPX3 | glutathione peroxidase 3 | 0.00709036 |
| KRT20 | keratin 20, type I | 0.00708144 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00701582 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00701156 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00699973 |
| DUSP1 | dual specificity phosphatase 1 | 0.00694717 |
| EPHB2 | EPH receptor B2 | 0.00691967 |
| CD9 | CD9 molecule | 0.00690986 |
| MYBPC1 | myosin binding protein C, slow type | 0.00687852 |
| KRT13 | keratin 13, type I | 0.0068389 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 0.00667034 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00661206 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00658199 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00655332 |
| GPX2 | glutathione peroxidase 2 | 0.00653556 |
| KRT17 | keratin 17, type I | 0.00650837 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00650506 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00646615 |
| S100A10 | S100 calcium binding protein A10 | 0.00644504 |
| TMEM45A | transmembrane protein 45A | 0.00634243 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00627049 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.00626919 |
| RHOB | ras homolog family member B | 0.00624363 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00623384 |
| HK2 | hexokinase 2 | 0.00616708 |
| FAM162A | family with sequence similarity 162, member A | 0.00616515 |
| AHSG | alpha-2-HS-glycoprotein | 0.00614425 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00613834 |
| CA9 | carbonic anhydrase IX | 0.00612821 |
| LOX | lysyl oxidase | 0.00611199 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00607012 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00605658 |
| STC2 | stanniocalcin 2 | 0.00604759 |
| FN1 | fibronectin 1 | 0.00602398 |
| CPB2 | carboxypeptidase B2 (plasma) | 0.00601888 |
| NNMT | nicotinamide N-methyltransferase | 0.0059757 |
| GCH1 | GTP cyclohydrolase 1 | 0.00595984 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00594588 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.00594248 |
| STX7 | syntaxin 7 | 0.00594097 |
| LOXL2 | lysyl oxidase-like 2 | 0.00593442 |
| PAH | phenylalanine hydroxylase | 0.00593389 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00590511 |
| TNNC1 | troponin C type 1 (slow) | 0.00588456 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00585257 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.0058284 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00582444 |
| TPD52L1 | tumor protein D52-like 1 | 0.00578849 |
| APOC3 | apolipoprotein C-III | 0.00577509 |
| ACKR3 | atypical chemokine receptor 3 | 0.00569076 |
| KLHL41 | kelch-like family member 41 | 0.00568443 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00567386 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00566961 |
| APOB | apolipoprotein B | 0.0056542 |
| CLCA4 | chloride channel accessory 4 | 0.00564881 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00561517 |
| MYBPC2 | myosin binding protein C, fast type | 0.00559524 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00554118 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00553916 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00553742 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00552656 |
| SNX5 | sorting nexin 5 | 0.00546393 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00546185 |
| SGCE | sarcoglycan, epsilon | 0.00545987 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.00545576 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.00545127 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.00542394 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | 0.00541832 |
| TNNC2 | troponin C type 2 (fast) | 0.00540228 |
| EPAS1 | endothelial PAS domain protein 1 | 0.005393 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00537373 |
| SPRR1B | small proline-rich protein 1B | 0.00537152 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00535802 |
| TPM3 | tropomyosin 3 | 0.00531012 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00527149 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00525789 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00525122 |
| HTRA1 | HtrA serine peptidase 1 | 0.00524616 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00523552 |
| PLS3 | plastin 3 | 0.00523403 |
| MEF2C | myocyte enhancer factor 2C | 0.00522797 |
| TCTA | T-cell leukemia translocation altered | 0.00519506 |
| SIK1 | salt-inducible kinase 1 | 0.00518001 |
| MYOT | myotilin | 0.00517902 |
| ALB | albumin | 0.0051771 |
| EZR | ezrin | 0.00516703 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0051637 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00514639 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.00513449 |
| MAP3K7CL | MAP3K7 C-terminal like | 0.00512841 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00512749 |
| NRCAM | neuronal cell adhesion molecule | 0.00511396 |
| MRPL17 | mitochondrial ribosomal protein L17 | 0.00509586 |
| ATP10D | ATPase, class V, type 10D | 0.00509412 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.0050921 |
| GPC3 | glypican 3 | 0.0050708 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00506618 |
| RAB1A | RAB1A, member RAS oncogene family | 0.00502612 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.00502523 |
| APOA2 | apolipoprotein A-II | 0.00502416 |
| SST | somatostatin | 0.00500563 |
| MRPL39 | mitochondrial ribosomal protein L39 | 0.00500128 |
| MRPS28 | mitochondrial ribosomal protein S28 | 0.0049916 |
| RTN2 | reticulon 2 | 0.00498185 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00497335 |
| EDNRB | endothelin receptor type B | 0.00496635 |
| CD69 | CD69 molecule | 0.00496592 |
| MMP2 | matrix metallopeptidase 2 | 0.00496579 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00495405 |
| CORO1C | coronin, actin binding protein, 1C | 0.0049481 |
| CNN3 | calponin 3, acidic | 0.0049346 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00493358 |
| MYO1B | myosin IB | 0.00493249 |
| TMEM14A | transmembrane protein 14A | 0.00491893 |
| FOXG1 | forkhead box G1 | 0.00490671 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | 0.00488314 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00487801 |
| CHI3L2 | chitinase 3-like 2 | 0.00487479 |
| GSN | gelsolin | 0.00484586 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00484289 |
| DCK | deoxycytidine kinase | 0.00482828 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00481729 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00480489 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | 0.00479985 |
| COL2A1 | collagen, type II, alpha 1 | 0.0047879 |
| SPRR1A | small proline-rich protein 1A | 0.00478689 |
| CD52 | CD52 molecule | 0.0047731 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0047676 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.00476676 |
| MYOZ2 | myozenin 2 | 0.00475132 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00474349 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.00473556 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 0.00471473 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.00468833 |
| COMMD3 | COMM domain containing 3 | 0.0046813 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00467738 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00466344 |
| LY96 | lymphocyte antigen 96 | 0.0046567 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.00465338 |
| PGK1 | phosphoglycerate kinase 1 | 0.00463558 |
| EDN1 | endothelin 1 | 0.00462825 |
| TCTN2 | tectonic family member 2 | 0.00462609 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | 0.00462418 |
| CA3 | carbonic anhydrase III | 0.00462222 |
| ELOB | elongin B | 0.00461841 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) | 0.00460454 |
| AFP | alpha-fetoprotein | 0.00459722 |
| MRPS33 | mitochondrial ribosomal protein S33 | 0.00459372 |
| MRPL13 | mitochondrial ribosomal protein L13 | 0.00458731 |
| CKM | creatine kinase, muscle | 0.00458518 |
| USO1 | USO1 vesicle transport factor | 0.00458428 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.0045712 |
| CADM1 | cell adhesion molecule 1 | 0.00454563 |
| PAX6 | paired box 6 | 0.00452813 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00452806 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00451928 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00451168 |
| IFRD2 | interferon-related developmental regulator 2 | 0.0045085 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00450295 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.00450258 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00449895 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.0044989 |
| HSBP1 | heat shock factor binding protein 1 | 0.00449752 |
| YIPF5 | Yip1 domain family, member 5 | 0.00448479 |
| ZNF721 | zinc finger protein 721 | 0.00447967 |
| SDC2 | syndecan 2 | 0.00447345 |
| LMBRD1 | LMBR1 domain containing 1 | 0.00446953 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.00446139 |
| PXDN | peroxidasin | 0.00445805 |
| GPR88 | G protein-coupled receptor 88 | 0.00445691 |
| AK1 | adenylate kinase 1 | 0.00445665 |
| GMFG | glia maturation factor, gamma | 0.00445288 |
| IVL | involucrin | 0.00445014 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.00443051 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00441564 |
| MED1 | mediator complex subunit 1 | 0.00441364 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.00441333 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.00440266 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.00440012 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0044001 |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 | 0.00439396 |
| MFSD1 | major facilitator superfamily domain containing 1 | 0.00438827 |
| CSTB | cystatin B (stefin B) | 0.0043801 |
| HYAL1 | hyaluronoglucosaminidase 1 | 0.00436763 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | 0.00436337 |
| PSG5 | pregnancy specific beta-1-glycoprotein 5 | 0.00436086 |
| GRB2 | growth factor receptor-bound protein 2 | 0.00435248 |
| TGFB2 | transforming growth factor, beta 2 | 0.00434903 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.00434411 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00433903 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00433442 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.004331 |
| PGBD5 | piggyBac transposable element derived 5 | 0.00432826 |
| CYTL1 | cytokine-like 1 | 0.00432583 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.00432555 |
| HMOX2 | heme oxygenase 2 | 0.0043249 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00432435 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00432364 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.00431716 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00431085 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00430593 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0042997 |
| CNN2 | calponin 2 | 0.00429313 |
| PEG10 | paternally expressed 10 | 0.00429289 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.00428882 |
| CA12 | carbonic anhydrase XII | 0.00428872 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00428697 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | 0.00428643 |
| DOK5 | docking protein 5 | 0.00428394 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 | 0.00428335 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00428294 |
| CASD1 | CAS1 domain containing 1 | 0.00426392 |
| TMEM70 | transmembrane protein 70 | 0.00426213 |
| COMMD8 | COMM domain containing 8 | 0.00425519 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | -0.01464 |
| LTF | lactotransferrin | -0.0140662 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0124458 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.0114639 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0114058 |
| OLFM4 | olfactomedin 4 | -0.0111911 |
| ASRGL1 | asparaginase like 1 | -0.010942 |
| TMC5 | transmembrane channel-like 5 | -0.00954166 |
| APOD | apolipoprotein D | -0.0090035 |
| TSPYL5 | TSPY-like 5 | -0.00893196 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00872817 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00861952 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00858846 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00817886 |
| S100A12 | S100 calcium binding protein A12 | -0.00802419 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00788056 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00786368 |
| TARP | TCR gamma alternate reading frame protein | -0.00783368 |
| PROM1 | prominin 1 | -0.00776806 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00776575 |
| RNF144A | ring finger protein 144A | -0.00765037 |
| RTN3 | reticulon 3 | -0.00762327 |
| CHRDL1 | chordin-like 1 | -0.00745004 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00738098 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00737663 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00732083 |
| BAD | BCL2-associated agonist of cell death | -0.00728828 |
| CHKB | choline kinase beta | -0.00725567 |
| HOXB2 | homeobox B2 | -0.00715634 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00714646 |
| RGS5 | regulator of G-protein signaling 5 | -0.00713765 |
| ACP3 | acid phosphatase 3 | -0.00711431 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00706686 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00701009 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00699948 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00698847 |
| PNMA8A | PNMA family member 8A | -0.00695737 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00689701 |
| MGP | matrix Gla protein | -0.00689127 |
| PNMA1 | paraneoplastic Ma antigen 1 | -0.00685767 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00685359 |
| NEFH | neurofilament, heavy polypeptide | -0.00685041 |
| HMGA1 | high mobility group AT-hook 1 | -0.00681244 |
| NKX3-1 | NK3 homeobox 1 | -0.00681209 |
| MX1 | MX dynamin-like GTPase 1 | -0.00676972 |
| DLG5 | discs, large homolog 5 (Drosophila) | -0.00676379 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00675612 |
| EPCAM | epithelial cell adhesion molecule | -0.00674541 |
| GALC | galactosylceramidase | -0.00672282 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00669557 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00654031 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00652581 |
| FASN | fatty acid synthase | -0.00650358 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | -0.00649587 |
| MLPH | melanophilin | -0.00646067 |
| C5AR1 | complement component 5a receptor 1 | -0.00642454 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00636445 |
| TNS1 | tensin 1 | -0.00635961 |
| GOLM1 | golgi membrane protein 1 | -0.00635021 |
| SELENBP1 | selenium binding protein 1 | -0.00633598 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00631385 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00628641 |
| AGR2 | anterior gradient 2 | -0.00627323 |
| PLBD1 | phospholipase B domain containing 1 | -0.00622823 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00622341 |
| EHF | ets homologous factor | -0.00617938 |
| STON1 | stonin 1 | -0.0061708 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00613265 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00609867 |
| GAS1 | growth arrest-specific 1 | -0.00607561 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00607214 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00606724 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00605677 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.00602242 |
| EMP3 | epithelial membrane protein 3 | -0.00601325 |
| HOXC6 | homeobox C6 | -0.00599655 |
| SVIL | supervillin | -0.00598008 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit | -0.00596856 |
| NPTXR | neuronal pentraxin receptor | -0.005966 |
| MUC4 | mucin 4, cell surface associated | -0.00596354 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00594974 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | -0.00590865 |
| RNF19B | ring finger protein 19B | -0.00588455 |
| G0S2 | G0/G1 switch 2 | -0.00586292 |
| RUNX3 | runt-related transcription factor 3 | -0.00585297 |
| XK | X-linked Kx blood group | -0.00584692 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | -0.0057946 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | -0.00574727 |
| KLK2 | kallikrein-related peptidase 2 | -0.00574266 |
| CPM | carboxypeptidase M | -0.00572904 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 | -0.00571954 |
| CNN1 | calponin 1, basic, smooth muscle | -0.00571594 |
| DMXL2 | Dmx-like 2 | -0.00569715 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00568992 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00568306 |
| MSMB | microseminoprotein, beta- | -0.0056773 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | -0.00567648 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00566403 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00563859 |
| MCM7 | minichromosome maintenance complex component 7 | -0.00561995 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00561025 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00559201 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00556966 |
| YBX3 | Y box binding protein 3 | -0.00551747 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00551061 |
| MEPCE | methylphosphate capping enzyme | -0.00550536 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00549735 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00549619 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | -0.00548339 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00547548 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00545052 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | -0.00545007 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00543967 |
| KLK11 | kallikrein-related peptidase 11 | -0.00543757 |
| KLK3 | kallikrein-related peptidase 3 | -0.00541197 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00540959 |
| TRIM28 | tripartite motif containing 28 | -0.00540912 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00540735 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.00540089 |
| AOC3 | amine oxidase, copper containing 3 | -0.00540075 |
| NBEA | neurobeachin | -0.00538774 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00537191 |
| FBLN2 | fibulin 2 | -0.00537141 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00536494 |
| S100A9 | S100 calcium binding protein A9 | -0.00536041 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00534201 |
| BPI | bactericidal/permeability-increasing protein | -0.00532588 |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | -0.0052897 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0052833 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00527473 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00525586 |
| OAT | ornithine aminotransferase | -0.00523933 |
| PGD | phosphogluconate dehydrogenase | -0.00522337 |
| CRAT | carnitine O-acetyltransferase | -0.00521938 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00521886 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00521805 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00521328 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00521152 |
| PLCL1 | phospholipase C-like 1 | -0.0052099 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0052097 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00519574 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00518593 |
| TMSB15A | thymosin beta 15a | -0.00517138 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00516731 |
| MAPK13 | mitogen-activated protein kinase 13 | -0.00516019 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0051589 |
| COL3A1 | collagen, type III, alpha 1 | -0.00514751 |
| GLG1 | golgi glycoprotein 1 | -0.0051347 |
| TBCD | tubulin folding cofactor D | -0.0051252 |
| DCN | decorin | -0.00512517 |
| S100A6 | S100 calcium binding protein A6 | -0.00511959 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0051194 |
| CDC20 | cell division cycle 20 | -0.00511559 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | -0.00511147 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | -0.00509879 |
| DPT | dermatopontin | -0.00509273 |
| INTS1 | integrator complex subunit 1 | -0.00505737 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00505425 |
| CFB | complement factor B | -0.00505193 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -0.00504734 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00503319 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00502031 |
| MMP8 | matrix metallopeptidase 8 | -0.00500743 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00500693 |
| VCAN | versican | -0.00500344 |
| GOLGA8A | golgin A8 family, member A | -0.0050009 |
| COL1A1 | collagen, type I, alpha 1 | -0.0049955 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00498316 |
| ATXN1 | ataxin 1 | -0.00496581 |
| IRS2 | insulin receptor substrate 2 | -0.00495657 |
| FAAH | fatty acid amide hydrolase | -0.00494895 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.00494792 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00494743 |
| KIF13B | kinesin family member 13B | -0.00494538 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00493175 |
| MAGEB2 | melanoma antigen family B2 | -0.00492452 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00491647 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00490504 |
| VARS | valyl-tRNA synthetase | -0.00489213 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00487803 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00486914 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00486176 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0048611 |
| LAMA2 | laminin, alpha 2 | -0.00486042 |
| BRD4 | bromodomain containing 4 | -0.0048551 |
| NLGN4X | neuroligin 4, X-linked | -0.00484406 |
| ZNF516 | zinc finger protein 516 | -0.00483633 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00483354 |
| CS | citrate synthase | -0.00483337 |
| CLGN | calmegin | -0.00480921 |
| CBX6 | chromobox homolog 6 | -0.00478216 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00477732 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00477001 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00476472 |
| PDZD8 | PDZ domain containing 8 | -0.00474711 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | -0.00473877 |
| PRPF4 | pre-mRNA processing factor 4 | -0.0047379 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.00473208 |
| FBLN1 | fibulin 1 | -0.00473097 |
| ZNF318 | zinc finger protein 318 | -0.00472541 |
| MLF1 | myeloid leukemia factor 1 | -0.00471995 |
| SLC2A4RG | SLC2A4 regulator | -0.00471156 |
| KLHL21 | kelch-like family member 21 | -0.00471062 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00469639 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -0.00469468 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0046899 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00467887 |
| ANXA6 | annexin A6 | -0.00467213 |
| NMU | neuromedin U | -0.00466625 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 | -0.00466546 |
| UBAC1 | UBA domain containing 1 | -0.00466028 |
| TJP2 | tight junction protein 2 | -0.00465844 |
| CLSTN1 | calsyntenin 1 | -0.0046386 |
| PRSS8 | protease, serine, 8 | -0.00461965 |
| DEFB1 | defensin, beta 1 | -0.00461771 |
| STK3 | serine/threonine kinase 3 | -0.00461222 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00460842 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.00460618 |
| GLB1L2 | galactosidase, beta 1-like 2 | -0.00460279 |
| GAS6 | growth arrest-specific 6 | -0.00459776 |
| EGR3 | early growth response 3 | -0.00459698 |
| GOLGA8H | golgin A8 family, member H | -0.00459592 |
| AHCY | adenosylhomocysteinase | -0.00459292 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00458763 |
| DVL1 | dishevelled segment polarity protein 1 | -0.00458457 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00458396 |
| PLAT | plasminogen activator, tissue | -0.00457895 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00456959 |
| ARRB2 | arrestin, beta 2 | -0.00454779 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00452674 |
| CCNF | cyclin F | -0.00452298 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00450838 |
| H2AX | H2A.X variant histone | -0.00449671 |
| ZNF239 | zinc finger protein 239 | -0.00448851 |
| NINL | ninein-like | -0.00448472 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00448084 |
| CTBP2 | C-terminal binding protein 2 | -0.00447977 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00447594 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00447483 |
| IL1R1 | interleukin 1 receptor, type I | -0.00446916 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00445808 |
| INSR | insulin receptor | -0.00445581 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00444216 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00444033 |
| CCDC176 | coiled-coil domain containing 176 | -0.00443668 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00442215 |
| MX2 | MX dynamin-like GTPase 2 | -0.00441516 |
| TRRAP | transformation/transcription domain-associated protein | -0.00436044 |
| JAG2 | jagged 2 | -0.00435057 |
