| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | toll-like receptor 6|The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011] (NCBI Entrez Gene Database, 10333) |
| External Link | https://ncbi.nlm.nih.gov/gene/10333 |
| Similar Terms | |
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500 genes differentially expressed following the TLR6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0118639 |
| PCP4 | Purkinje cell protein 4 | 0.0118034 |
| SNX7 | sorting nexin 7 | 0.0108389 |
| PRDX2 | peroxiredoxin 2 | 0.0108077 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0103554 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0103023 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0101771 |
| COL1A2 | collagen, type I, alpha 2 | 0.00973671 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00950173 |
| XIC | X chromosome inactivation center | 0.00942789 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00939532 |
| DACH1 | dachshund family transcription factor 1 | 0.00927029 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00901352 |
| AURKB | aurora kinase B | 0.0089994 |
| OLFM4 | olfactomedin 4 | 0.00897768 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00888479 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.0085196 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00836981 |
| KIF20A | kinesin family member 20A | 0.00821976 |
| NEFH | neurofilament, heavy polypeptide | 0.00813148 |
| AGR2 | anterior gradient 2 | 0.00812411 |
| NELL2 | NEL-like 2 (chicken) | 0.00807498 |
| AUTS2 | autism susceptibility candidate 2 | 0.00799332 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00797824 |
| RAPSN | receptor-associated protein of the synapse | 0.00787397 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00771698 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00769232 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00767491 |
| MMP3 | matrix metallopeptidase 3 | 0.0076731 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00755362 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.00749944 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00744368 |
| ACP3 | acid phosphatase 3 | 0.00743785 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00735729 |
| CHGB | chromogranin B | 0.0073358 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00732678 |
| SIRT3 | sirtuin 3 | 0.00729726 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00721581 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00716414 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00715581 |
| NES | nestin | 0.00709762 |
| ARG2 | arginase 2 | 0.007007 |
| RXRA | retinoid X receptor, alpha | 0.00700331 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00698701 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00698086 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00695115 |
| SFTPB | surfactant protein B | 0.006944 |
| MYLK | myosin light chain kinase | 0.00691884 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00680192 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00679897 |
| KIF18B | kinesin family member 18B | 0.00676689 |
| KIF15 | kinesin family member 15 | 0.00671293 |
| STON1 | stonin 1 | 0.00670531 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.00663064 |
| LYZ | lysozyme | 0.00657822 |
| FAM120A | family with sequence similarity 120A | 0.00652979 |
| MMP2 | matrix metallopeptidase 2 | 0.00651874 |
| CPE | carboxypeptidase E | 0.00651388 |
| GLOD4 | glyoxalase domain containing 4 | 0.00650315 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00648854 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00648173 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00644916 |
| CERK | ceramide kinase | 0.00644722 |
| TRMT5 | tRNA methyltransferase 5 | 0.00643156 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00641936 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00637527 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00637296 |
| NTS | neurotensin | 0.00636004 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00635405 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.00629144 |
| HMG20B | high mobility group 20B | 0.00625754 |
| CTSZ | cathepsin Z | 0.00623032 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.00620499 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.00620397 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00618351 |
| CCND1 | cyclin D1 | 0.00616155 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00613352 |
| SLC35E2B | solute carrier family 35, member E2B | 0.00611696 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00610653 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00610055 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00607632 |
| TARP | TCR gamma alternate reading frame protein | 0.00605413 |
| SMTN | smoothelin | 0.00603476 |
| GLB1L2 | galactosidase, beta 1-like 2 | 0.0060125 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00600372 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.00600256 |
| A2M | alpha-2-macroglobulin | 0.00599703 |
| KLK2 | kallikrein-related peptidase 2 | 0.0059698 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00594356 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00592192 |
| MAGED1 | melanoma antigen family D1 | 0.00591439 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00590542 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.00589928 |
| ACO1 | aconitase 1, soluble | 0.00589443 |
| DGCR8 | DGCR8 microprocessor complex subunit | 0.00584486 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00582861 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | 0.00579408 |
| PER3 | period circadian clock 3 | 0.00578645 |
| BCHE | butyrylcholinesterase | 0.00573447 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00573208 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00573029 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00571792 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00568806 |
| KIF14 | kinesin family member 14 | 0.00568075 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.00567952 |
| PTCH1 | patched 1 | 0.00564459 |
| CIT | citron rho-interacting serine/threonine kinase | 0.00563973 |
| PTN | pleiotrophin | 0.00563624 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00563515 |
| DES | desmin | 0.00563239 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | 0.00561018 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.00559622 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | 0.00559208 |
| LBR | lamin B receptor | 0.00558316 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00556852 |
| DENND1B | DENN/MADD domain containing 1B | 0.00554975 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00554764 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | 0.00552276 |
| MMP1 | matrix metallopeptidase 1 | 0.00552149 |
| VANGL1 | VANGL planar cell polarity protein 1 | 0.00551497 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.0054849 |
| POSTN | periostin, osteoblast specific factor | 0.00547763 |
| INSIG1 | insulin induced gene 1 | 0.00546094 |
| SRP9 | signal recognition particle 9kDa | 0.00545822 |
| FANCL | Fanconi anemia, complementation group L | 0.00545505 |
| MATN2 | matrilin 2 | 0.00543456 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00542825 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00541915 |
| ITGA6 | integrin, alpha 6 | 0.00541173 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00540957 |
| DBF4 | DBF4 zinc finger | 0.00540868 |
| HYOU1 | hypoxia up-regulated 1 | 0.00539769 |
| CDC7 | cell division cycle 7 | 0.00539592 |
| PLN | phospholamban | 0.00537319 |
| EFHD2 | EF-hand domain family, member D2 | 0.00537259 |
| CCNF | cyclin F | 0.00535473 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.00535352 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.005349 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0053467 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 0.0053353 |
| FUS | FUS RNA binding protein | 0.00533261 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00533043 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0053239 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00531712 |
| TRIP13 | thyroid hormone receptor interactor 13 | 0.00530679 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00527817 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.00527271 |
| CBR3 | carbonyl reductase 3 | 0.00527241 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00525447 |
| OGN | osteoglycin | 0.00525153 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.00524457 |
| RNF130 | ring finger protein 130 | 0.00524001 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0052389 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00523476 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00522774 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00522752 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00522547 |
| BGN | biglycan | 0.00521435 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00521419 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00518429 |
| HMGB1 | high mobility group box 1 | 0.00517618 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00517509 |
| DCHS1 | dachsous cadherin-related 1 | 0.00517208 |
| SQLE | squalene epoxidase | 0.00517101 |
| S100P | S100 calcium binding protein P | 0.00516099 |
| KLK3 | kallikrein-related peptidase 3 | 0.00515721 |
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.00515584 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0051493 |
| FASN | fatty acid synthase | 0.00514273 |
| TGOLN2 | trans-golgi network protein 2 | 0.00513445 |
| MICU2 | mitochondrial calcium uptake 2 | 0.00512762 |
| FBXO11 | F-box protein 11 | 0.00512371 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00511319 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00510329 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00509907 |
| CA9 | carbonic anhydrase IX | 0.00506361 |
| TBC1D16 | TBC1 domain family, member 16 | 0.0050537 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00504422 |
| COPS7A | COP9 signalosome subunit 7A | 0.00504054 |
| ZBED5 | zinc finger, BED-type containing 5 | 0.00501901 |
| HMGB3 | high mobility group box 3 | 0.00501733 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00499543 |
| NDNF | neuron-derived neurotrophic factor | 0.00499475 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00499102 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00498989 |
| PCDH9 | protocadherin 9 | 0.00496665 |
| RBM38 | RNA binding motif protein 38 | 0.00494344 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.00494131 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00493494 |
| NADK | NAD kinase | 0.00493212 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.00492123 |
| MEIS2 | Meis homeobox 2 | 0.00491971 |
| MGP | matrix Gla protein | 0.00489713 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00489323 |
| IFT81 | intraflagellar transport 81 | 0.00488889 |
| FBN2 | fibrillin 2 | 0.00488494 |
| LRRC47 | leucine rich repeat containing 47 | 0.00488325 |
| PNMA8A | PNMA family member 8A | 0.00487047 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00485776 |
| ANXA6 | annexin A6 | 0.00485651 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.0048551 |
| CD9 | CD9 molecule | 0.00482869 |
| ISOC1 | isochorismatase domain containing 1 | 0.0048269 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00481155 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00481089 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00480527 |
| EDNRA | endothelin receptor type A | 0.00478764 |
| RAD21 | RAD21 homolog (S. pombe) | 0.00478426 |
| RRBP1 | ribosome binding protein 1 | 0.00478358 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00478274 |
| SYNM | synemin, intermediate filament protein | 0.00477662 |
| NDC80 | NDC80 kinetochore complex component | 0.00477354 |
| GPI | glucose-6-phosphate isomerase | 0.0047624 |
| MTMR11 | myotubularin related protein 11 | 0.0047544 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 | 0.00475173 |
| SUSD5 | sushi domain containing 5 | 0.00474816 |
| NVL | nuclear VCP-like | 0.00473926 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00472709 |
| CALCA | calcitonin-related polypeptide alpha | 0.00472174 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.00471925 |
| CLGN | calmegin | 0.00471672 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.00471197 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 0.00470847 |
| FOXM1 | forkhead box M1 | 0.00470461 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.00469329 |
| APMAP | adipocyte plasma membrane associated protein | 0.00468521 |
| OBSL1 | obscurin-like 1 | 0.00468497 |
| FBXO5 | F-box protein 5 | 0.00468216 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.00467262 |
| SCG5 | secretogranin V | 0.00467162 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00466985 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00466971 |
| CENPF | centromere protein F, 350/400kDa | 0.0046565 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.00465187 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.00465005 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0046464 |
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.00464346 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00464323 |
| PRKCA | protein kinase C, alpha | 0.00464289 |
| GNAS | GNAS complex locus | 0.00463829 |
| ACACA | acetyl-CoA carboxylase alpha | 0.00460559 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00460122 |
| PON3 | paraoxonase 3 | 0.00459981 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00459556 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0045911 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00458261 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.00458221 |
| NAV2 | neuron navigator 2 | 0.00456547 |
| GAL | galanin/GMAP prepropeptide | 0.00456197 |
| USP48 | ubiquitin specific peptidase 48 | 0.00455647 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | -0.0196573 |
| DEFB1 | defensin, beta 1 | -0.0163483 |
| MX1 | MX dynamin-like GTPase 1 | -0.0135877 |
| ATF3 | activating transcription factor 3 | -0.0131834 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0131117 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0129453 |
| C3 | complement component 3 | -0.0127869 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0124339 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0123063 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0120838 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0118617 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0116881 |
| MBD1 | methyl-CpG binding domain protein 1 | -0.0115424 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0114004 |
| TRIM22 | tripartite motif containing 22 | -0.011242 |
| CFB | complement factor B | -0.0111514 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.011131 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.0111222 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0109925 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0107921 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0107284 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0106501 |
| ANXA1 | annexin A1 | -0.0103723 |
| AREG | amphiregulin | -0.0103664 |
| HSPA1A | heat shock 70kDa protein 1A | -0.010282 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0102713 |
| CRYAB | crystallin, alpha B | -0.0102554 |
| MT1M | metallothionein 1M | -0.0101295 |
| IFI44L | interferon-induced protein 44-like | -0.010052 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.0100242 |
| NNMT | nicotinamide N-methyltransferase | -0.010001 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00985788 |
| CLU | clusterin | -0.00972953 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00966859 |
| MT1E | metallothionein 1E | -0.00960448 |
| CSTA | cystatin A (stefin A) | -0.00957221 |
| PROM1 | prominin 1 | -0.0093173 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00930288 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00929691 |
| RCAN1 | regulator of calcineurin 1 | -0.00925622 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00914048 |
| COBL | cordon-bleu WH2 repeat protein | -0.0091255 |
| IRF7 | interferon regulatory factor 7 | -0.00902919 |
| IL15 | interleukin 15 | -0.00897202 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00889959 |
| KLK10 | kallikrein-related peptidase 10 | -0.0088944 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00888972 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00888276 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00888215 |
| MFAP5 | microfibrillar associated protein 5 | -0.00886088 |
| RND3 | Rho family GTPase 3 | -0.00881644 |
| MT1X | metallothionein 1X | -0.00879294 |
| PLSCR1 | phospholipid scramblase 1 | -0.00876278 |
| CA2 | carbonic anhydrase II | -0.0086923 |
| H1-2 | H1.2 linker histone, cluster member | -0.00861621 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00860406 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00858063 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00850768 |
| CA12 | carbonic anhydrase XII | -0.00850574 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0084977 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00849285 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00848159 |
| RTP4 | receptor (chemosensory) transporter protein 4 | -0.00842047 |
| ADIRF | adipogenesis regulatory factor | -0.00836133 |
| KRT6A | keratin 6A, type II | -0.0083432 |
| BTG2 | BTG family, member 2 | -0.00834129 |
| MT1G | metallothionein 1G | -0.00831553 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00820953 |
| THBD | thrombomodulin | -0.00819787 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00817574 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00816307 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00811386 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00808466 |
| GLRX | glutaredoxin (thioltransferase) | -0.0080173 |
| DAXX | death-domain associated protein | -0.0078976 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00789556 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00786898 |
| MT1F | metallothionein 1F | -0.00780781 |
| KRT23 | keratin 23, type I | -0.00777509 |
| SP100 | SP100 nuclear antigen | -0.00773154 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00772429 |
| IFI44 | interferon-induced protein 44 | -0.00768169 |
| FOLR1 | folate receptor 1 (adult) | -0.00764058 |
| LY75 | lymphocyte antigen 75 | -0.0076188 |
| STK17A | serine/threonine kinase 17a | -0.00757042 |
| IQCG | IQ motif containing G | -0.00754866 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00752651 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.00751351 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.00746191 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00745857 |
| MYO1C | myosin IC | -0.0074359 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00743066 |
| KIAA0040 | KIAA0040 | -0.00741356 |
| KRT6B | keratin 6B, type II | -0.00735032 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00734404 |
| ABLIM1 | actin binding LIM protein 1 | -0.00732685 |
| BTG3 | BTG family, member 3 | -0.00731335 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00730918 |
| TMEM140 | transmembrane protein 140 | -0.00727015 |
| KRT19 | keratin 19, type I | -0.00726817 |
| CLIC5 | chloride intracellular channel 5 | -0.00721911 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00721575 |
| EMP1 | epithelial membrane protein 1 | -0.00721152 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00721144 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00720113 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00717813 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00717713 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.007141 |
| IL6 | interleukin 6 | -0.00713024 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00712233 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00711838 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.007099 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.00706949 |
| MX2 | MX dynamin-like GTPase 2 | -0.00702972 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00702633 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00700567 |
| E2F2 | E2F transcription factor 2 | -0.00696437 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.0069628 |
| FGB | fibrinogen beta chain | -0.0069282 |
| EMX2 | empty spiracles homeobox 2 | -0.00688802 |
| CLDN10 | claudin 10 | -0.00688457 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00687796 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00686404 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00684619 |
| GPX1 | glutathione peroxidase 1 | -0.00683517 |
| GLUL | glutamate-ammonia ligase | -0.00682548 |
| LY86 | lymphocyte antigen 86 | -0.00681248 |
| LXN | latexin | -0.00681203 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00677539 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00677214 |
| ADM | adrenomedullin | -0.0067516 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00674255 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00673354 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00672585 |
| RGS10 | regulator of G-protein signaling 10 | -0.00671119 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00670328 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00669448 |
| APOC1 | apolipoprotein C-I | -0.00668525 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00665549 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -0.0066533 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.0066347 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00661812 |
| KLK6 | kallikrein-related peptidase 6 | -0.00661084 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00659411 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00658852 |
| S100A14 | S100 calcium binding protein A14 | -0.00656889 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00653377 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00649015 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00648145 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00646822 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.0064589 |
| MVP | major vault protein | -0.00644959 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00644775 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00644017 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.00643372 |
| UPK1B | uroplakin 1B | -0.00642577 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00637364 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00636075 |
| S100A9 | S100 calcium binding protein A9 | -0.00635256 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | -0.0063304 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma | -0.00631894 |
| MT1H | metallothionein 1H | -0.00631135 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00627334 |
| KLF6 | Kruppel-like factor 6 | -0.0062733 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00625874 |
| DUSP5 | dual specificity phosphatase 5 | -0.00625871 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00625144 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.0062456 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00623392 |
| RGS4 | regulator of G-protein signaling 4 | -0.00623298 |
| MAL | mal, T-cell differentiation protein | -0.00622217 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00621866 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00621321 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00616635 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00615832 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00615138 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00614068 |
| GRAMD2B | GRAM domain containing 2B | -0.00613494 |
| KRT13 | keratin 13, type I | -0.00612991 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.00612865 |
| FHL2 | four and a half LIM domains 2 | -0.006126 |
| APOC2 | apolipoprotein C-II | -0.00612588 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0061101 |
| PTK2 | protein tyrosine kinase 2 | -0.00610903 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00610499 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00609773 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00609249 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00607622 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00605418 |
| HOXB7 | homeobox B7 | -0.0060386 |
| VTN | vitronectin | -0.00602468 |
| SP110 | SP110 nuclear body protein | -0.0060095 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00599616 |
| IER5 | immediate early response 5 | -0.00598954 |
| SNX11 | sorting nexin 11 | -0.00598551 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00598297 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0059688 |
| GTF2B | general transcription factor IIB | -0.00595495 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.00595489 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.00592398 |
| PCLAF | PCNA clamp associated factor | -0.00592079 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00587044 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00586543 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00586257 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.00586169 |
| C1S | complement component 1, s subcomponent | -0.00585049 |
| TSPAN3 | tetraspanin 3 | -0.00580232 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -0.00578581 |
| SATB2 | SATB homeobox 2 | -0.00578205 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00575951 |
| STC1 | stanniocalcin 1 | -0.00575087 |
| TXN | thioredoxin | -0.00571394 |
| KRT5 | keratin 5, type II | -0.00571227 |
| RRAD | Ras-related associated with diabetes | -0.00570777 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0057055 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00569922 |
| TMEM59 | transmembrane protein 59 | -0.00568439 |
| OPTN | optineurin | -0.00568034 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00567128 |
| KRT7 | keratin 7, type II | -0.00567059 |
| XAF1 | XIAP associated factor 1 | -0.0056644 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | -0.00565653 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00565398 |
| ELP3 | elongator acetyltransferase complex subunit 3 | -0.00564816 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00564634 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00564469 |
| CLCA4 | chloride channel accessory 4 | -0.00561472 |
| SCEL | sciellin | -0.00559537 |
| KRT15 | keratin 15, type I | -0.00559345 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.00557443 |
| PALMD | palmdelphin | -0.0055555 |
| KLK7 | kallikrein-related peptidase 7 | -0.00553272 |
| RPS27L | ribosomal protein S27-like | -0.0055316 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.00552963 |
| GPER1 | G protein-coupled estrogen receptor 1 | -0.0055275 |
| TRIM38 | tripartite motif containing 38 | -0.00551909 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00550624 |
| MUC16 | mucin 16, cell surface associated | -0.00549969 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.00549324 |
| HMOX1 | heme oxygenase 1 | -0.00547771 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00546202 |
| FOXD1 | forkhead box D1 | -0.00545835 |
| RHCG | Rh family, C glycoprotein | -0.00545392 |
| IFI35 | interferon-induced protein 35 | -0.00542873 |
| GAS1 | growth arrest-specific 1 | -0.00540923 |
| IL1R1 | interleukin 1 receptor, type I | -0.00540594 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00540174 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00539656 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00539556 |
| CLTB | clathrin, light chain B | -0.00539402 |
