| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | toll-like receptor 7|The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 51284) |
| External Link | https://ncbi.nlm.nih.gov/gene/51284 |
| Similar Terms | |
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499 genes differentially expressed following the TLR7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.013862 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0136482 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0123335 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0112681 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0109743 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0107999 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0106913 |
| MAP7 | microtubule-associated protein 7 | 0.00995652 |
| XIC | X chromosome inactivation center | 0.00984364 |
| AUTS2 | autism susceptibility candidate 2 | 0.0093575 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00899683 |
| MAGEA3 | melanoma antigen family A3 | 0.00886102 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0088467 |
| PCDH9 | protocadherin 9 | 0.00854556 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00850646 |
| TARP | TCR gamma alternate reading frame protein | 0.00842988 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00836488 |
| PAX5 | paired box 5 | 0.00829162 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00819718 |
| KRT15 | keratin 15, type I | 0.00790118 |
| S100A12 | S100 calcium binding protein A12 | 0.00789919 |
| CALB1 | calbindin 1, 28kDa | 0.00782456 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00782198 |
| CD320 | CD320 molecule | 0.00778584 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00773304 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00754616 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00747686 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00746663 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00743304 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00732201 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00727852 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00725383 |
| S100P | S100 calcium binding protein P | 0.00719192 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00715503 |
| MGAM | maltase-glucoamylase | 0.00714541 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00710961 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00710406 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00702969 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00702894 |
| ADD3 | adducin 3 (gamma) | 0.00695885 |
| NEBL | nebulette | 0.00691768 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00684158 |
| BGN | biglycan | 0.00684112 |
| ATF4 | activating transcription factor 4 | 0.00683507 |
| HK2 | hexokinase 2 | 0.00680727 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00680014 |
| POU4F1 | POU class 4 homeobox 1 | 0.00678797 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00668247 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00668112 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00668061 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00662252 |
| RPN2 | ribophorin II | 0.00652684 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00652062 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00651457 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00651279 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0064409 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00641579 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00641322 |
| FABP7 | fatty acid binding protein 7, brain | 0.00639236 |
| CDC7 | cell division cycle 7 | 0.00637578 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00634429 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00633075 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00632583 |
| TESC | tescalcin | 0.00632409 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00632296 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00631997 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 0.00627769 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.00627475 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00626231 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00625263 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.00625179 |
| SIRT3 | sirtuin 3 | 0.00624866 |
| HTRA1 | HtrA serine peptidase 1 | 0.00624078 |
| CAMP | cathelicidin antimicrobial peptide | 0.00620646 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00619535 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00617997 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00617481 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00616208 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00615298 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00614847 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00613752 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00612514 |
| IRS2 | insulin receptor substrate 2 | 0.00612464 |
| NDNF | neuron-derived neurotrophic factor | 0.0061 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.0060882 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | 0.00600783 |
| CLDN1 | claudin 1 | 0.00599211 |
| MSLN | mesothelin | 0.00599169 |
| DSG3 | desmoglein 3 | 0.00598563 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.00596583 |
| MAGEA12 | melanoma antigen family A12 | 0.00595579 |
| MAGEA4 | melanoma antigen family A4 | 0.00595524 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00591588 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.00590051 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00586478 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00585543 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.00582493 |
| CLASRP | CLK4-associating serine/arginine rich protein | 0.00581832 |
| GSPT2 | G1 to S phase transition 2 | 0.00581514 |
| TSPAN8 | tetraspanin 8 | 0.00580189 |
| ANXA3 | annexin A3 | 0.00578632 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0057842 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.0057813 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00575171 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00575163 |
| POMZP3 | POM121 and ZP3 fusion | 0.00569326 |
| LCN2 | lipocalin 2 | 0.00569044 |
| SORD | sorbitol dehydrogenase | 0.00566039 |
| EHD3 | EH-domain containing 3 | 0.00566001 |
| COMT | catechol-O-methyltransferase | 0.00562434 |
| PRAME | preferentially expressed antigen in melanoma | 0.00557984 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.00557012 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00554929 |
| IL5RA | interleukin 5 receptor, alpha | 0.00554699 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 0.00553739 |
| ARPC5L | actin related protein 2/3 complex, subunit 5-like | 0.00553473 |
| IPO13 | importin 13 | 0.00553345 |
| IL2RG | interleukin 2 receptor, gamma | 0.00551991 |
| MMP12 | matrix metallopeptidase 12 | 0.00551928 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0054871 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00542871 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | 0.005393 |
| INHBA | inhibin, beta A | 0.00537109 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00535021 |
| RPA2 | replication protein A2, 32kDa | 0.0053247 |
| NRN1 | neuritin 1 | 0.00531449 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.00530567 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00529365 |
| TGFA | transforming growth factor, alpha | 0.00527611 |
| NEFH | neurofilament, heavy polypeptide | 0.00526723 |
| NUP50 | nucleoporin 50kDa | 0.00526401 |
| SCEL | sciellin | 0.00525227 |
| RAB5IF | RAB5 interacting factor | 0.00524994 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00524452 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00524215 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00524211 |
| TPD52L1 | tumor protein D52-like 1 | 0.00524047 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00523926 |
| NDC80 | NDC80 kinetochore complex component | 0.00523755 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.00523116 |
| SPEN | spen family transcriptional repressor | 0.00521635 |
| HIRA | histone cell cycle regulator | 0.0051938 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.00515762 |
| PDZD8 | PDZ domain containing 8 | 0.00513575 |
| TMC6 | transmembrane channel-like 6 | 0.00512884 |
| NOX1 | NADPH oxidase 1 | 0.0051095 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00507661 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00507081 |
| KIF20A | kinesin family member 20A | 0.00506028 |
| BRD4 | bromodomain containing 4 | 0.00504936 |
| BPI | bactericidal/permeability-increasing protein | 0.00504194 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.0049897 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00498202 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00497322 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 | 0.00495785 |
| GPSM3 | G-protein signaling modulator 3 | 0.00495749 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00491747 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00491515 |
| HDC | histidine decarboxylase | 0.0049137 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00491203 |
| RGS13 | regulator of G-protein signaling 13 | 0.00491201 |
| ODC1 | ornithine decarboxylase 1 | 0.00490513 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00490108 |
| CD19 | CD19 molecule | 0.00489984 |
| MMP9 | matrix metallopeptidase 9 | 0.00489416 |
| PF4 | platelet factor 4 | 0.00488925 |
| ABLIM1 | actin binding LIM protein 1 | 0.00488601 |
| YME1L1 | YME1-like 1 ATPase | 0.00488176 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00486938 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00486491 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00484577 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00482978 |
| CCDC47 | coiled-coil domain containing 47 | 0.00481177 |
| SFTPD | surfactant protein D | 0.00481164 |
| TECR | trans-2,3-enoyl-CoA reductase | 0.0048099 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.0048029 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00480153 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00478581 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00477854 |
| ADIRF | adipogenesis regulatory factor | 0.00474383 |
| LTF | lactotransferrin | 0.00474324 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00473485 |
| WIF1 | WNT inhibitory factor 1 | 0.00471847 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 | 0.00471267 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00470214 |
| UNC45A | unc-45 homolog A (C. elegans) | 0.00469375 |
| EPHA2 | EPH receptor A2 | 0.00467391 |
| CST1 | cystatin SN | 0.00466705 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0046623 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00464451 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.00463792 |
| CHIT1 | chitinase 1 (chitotriosidase) | 0.00463758 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00462376 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00461736 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.004614 |
| RNF43 | ring finger protein 43 | 0.00460926 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.00460549 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00460392 |
| HOXA1 | homeobox A1 | 0.00458685 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0045663 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.00456466 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00456437 |
| SLC35E2B | solute carrier family 35, member E2B | 0.00454597 |
| FST | follistatin | 0.00454586 |
| STK10 | serine/threonine kinase 10 | 0.00452499 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.00451612 |
| DPEP1 | dipeptidase 1 (renal) | 0.00450682 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.00450475 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00450054 |
| NOTCH1 | notch 1 | 0.00449813 |
| RHOB | ras homolog family member B | 0.00448754 |
| NUP85 | nucleoporin 85kDa | 0.00448539 |
| ERF | Ets2 repressor factor | 0.00447801 |
| EPX | eosinophil peroxidase | 0.00447553 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 0.004469 |
| NCOR1 | nuclear receptor corepressor 1 | 0.00446652 |
| CA10 | carbonic anhydrase X | 0.00446298 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.00446072 |
| FAIM | Fas apoptotic inhibitory molecule | 0.00445871 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 | 0.00444612 |
| CLC | Charcot-Leyden crystal galectin | 0.00444467 |
| BCCIP | BRCA2 and CDKN1A interacting protein | 0.0044369 |
| ITGA8 | integrin, alpha 8 | 0.00443578 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00443363 |
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | 0.00443221 |
| NMRK1 | nicotinamide riboside kinase 1 | 0.00443208 |
| PGLYRP1 | peptidoglycan recognition protein 1 | 0.00443161 |
| ATP10B | ATPase, class V, type 10B | 0.00442606 |
| IRX5 | iroquois homeobox 5 | 0.00442371 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.00442368 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00439834 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00439232 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0043855 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.00438465 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00438407 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | 0.00437965 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.00437341 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.0043687 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.00436859 |
| ATXN10 | ataxin 10 | 0.00436591 |
| C1ORF116 | chromosome 1 open reading frame 116 | 0.00436018 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00435773 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00435557 |
| GGT1 | gamma-glutamyltransferase 1 | 0.00434707 |
| NDRG3 | NDRG family member 3 | 0.00433894 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0043306 |
| STAG3 | stromal antigen 3 | 0.00432823 |
| GFAP | glial fibrillary acidic protein | 0.00432112 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00431577 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEPP1 | selenoprotein P, plasma, 1 | -0.0160605 |
| ASPN | asporin | -0.0160395 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0148334 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0135223 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0132538 |
| PEG3 | paternally expressed 3 | -0.0130389 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0126563 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0124967 |
| COL15A1 | collagen, type XV, alpha 1 | -0.012137 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0121182 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.0119752 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0118719 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0118559 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.0118085 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0117658 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0117424 |
| MFAP5 | microfibrillar associated protein 5 | -0.0115043 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0113131 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0111222 |
| ACKR3 | atypical chemokine receptor 3 | -0.0109861 |
| DEFB1 | defensin, beta 1 | -0.0109672 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0109552 |
| IRF8 | interferon regulatory factor 8 | -0.0109536 |
| LRRC17 | leucine rich repeat containing 17 | -0.0109435 |
| HNMT | histamine N-methyltransferase | -0.0108921 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.0108178 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0108012 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0104743 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.0104451 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0104387 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.0103428 |
| FGL2 | fibrinogen-like 2 | -0.0102692 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0102519 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.0102104 |
| PLAT | plasminogen activator, tissue | -0.0102055 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.0101963 |
| DCN | decorin | -0.0101493 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.0101128 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00965246 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.0095929 |
| FBLN1 | fibulin 1 | -0.00956641 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00954969 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00952593 |
| RGS5 | regulator of G-protein signaling 5 | -0.00949747 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00941286 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00935211 |
| C1S | complement component 1, s subcomponent | -0.0093487 |
| TMEM45A | transmembrane protein 45A | -0.00931552 |
| PFN2 | profilin 2 | -0.00931062 |
| GAS1 | growth arrest-specific 1 | -0.00930418 |
| RNF167 | ring finger protein 167 | -0.00929427 |
| MEIS1 | Meis homeobox 1 | -0.00920226 |
| PLN | phospholamban | -0.00914352 |
| CDC20 | cell division cycle 20 | -0.00899708 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.0089104 |
| CTSK | cathepsin K | -0.00887347 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00870839 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00866143 |
| DSE | dermatan sulfate epimerase | -0.0086359 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00861777 |
| C3 | complement component 3 | -0.00857253 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00846805 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00841713 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00835461 |
| MTMR11 | myotubularin related protein 11 | -0.00820744 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00819276 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0081927 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00818853 |
| DST | dystonin | -0.008168 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00815483 |
| GPR183 | G protein-coupled receptor 183 | -0.00815048 |
| OGN | osteoglycin | -0.00805384 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00804484 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00803035 |
| ANXA5 | annexin A5 | -0.00800765 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00796805 |
| RCAN2 | regulator of calcineurin 2 | -0.00794269 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00794251 |
| ASPH | aspartate beta-hydroxylase | -0.00794032 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00791705 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00789814 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00788675 |
| CHRDL1 | chordin-like 1 | -0.00786443 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00784912 |
| CALHM2 | calcium homeostasis modulator 2 | -0.00781957 |
| S100A7 | S100 calcium binding protein A7 | -0.00778857 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00775922 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00773315 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00772134 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00769712 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00768889 |
| MGLL | monoglyceride lipase | -0.00768272 |
| A2M | alpha-2-macroglobulin | -0.00767975 |
| BAG2 | BCL2-associated athanogene 2 | -0.0076753 |
| SETBP1 | SET binding protein 1 | -0.00766231 |
| PMP22 | peripheral myelin protein 22 | -0.00765019 |
| SST | somatostatin | -0.00761518 |
| CA2 | carbonic anhydrase II | -0.00754706 |
| MT1E | metallothionein 1E | -0.0075377 |
| NID1 | nidogen 1 | -0.0075352 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00752132 |
| CST3 | cystatin C | -0.00749807 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00749618 |
| OLFML3 | olfactomedin-like 3 | -0.00747522 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00747332 |
| NUTF2 | nuclear transport factor 2 | -0.00745737 |
| MDFIC | MyoD family inhibitor domain containing | -0.00744617 |
| AXL | AXL receptor tyrosine kinase | -0.00742363 |
| THBS1 | thrombospondin 1 | -0.00738424 |
| FOXF1 | forkhead box F1 | -0.00734282 |
| ADA | adenosine deaminase | -0.00733398 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00729581 |
| FHL1 | four and a half LIM domains 1 | -0.00728415 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00727742 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00726095 |
| IFI44L | interferon-induced protein 44-like | -0.00720989 |
| CD99 | CD99 molecule | -0.00719302 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00716962 |
| CLU | clusterin | -0.0071655 |
| TMEM176B | transmembrane protein 176B | -0.00716272 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.0071539 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00712389 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00706631 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00700462 |
| HOXB2 | homeobox B2 | -0.00697924 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00697134 |
| SMAD3 | SMAD family member 3 | -0.00697081 |
| SNAI2 | snail family zinc finger 2 | -0.00696565 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00695719 |
| MIR22HG | MIR22 host gene | -0.00695327 |
| MSX1 | msh homeobox 1 | -0.00692427 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0068946 |
| TOX3 | TOX high mobility group box family member 3 | -0.00689417 |
| LDB2 | LIM domain binding 2 | -0.00688684 |
| MYLK | myosin light chain kinase | -0.00687584 |
| COLEC12 | collectin sub-family member 12 | -0.00686808 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00684841 |
| CLIC2 | chloride intracellular channel 2 | -0.00683086 |
| TPM2 | tropomyosin 2 (beta) | -0.00682208 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00682106 |
| MITF | microphthalmia-associated transcription factor | -0.00679189 |
| CP | ceruloplasmin (ferroxidase) | -0.0067712 |
| ADM | adrenomedullin | -0.00675867 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00675379 |
| LXN | latexin | -0.00674437 |
| RUFY2 | RUN and FYVE domain containing 2 | -0.00673727 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0066795 |
| CFH | complement factor H | -0.00667822 |
| LOXL1 | lysyl oxidase-like 1 | -0.00667725 |
| TMSB15A | thymosin beta 15a | -0.00667253 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -0.00667215 |
| PALMD | palmdelphin | -0.00666614 |
| XPO7 | exportin 7 | -0.00665479 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00663483 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00663023 |
| THBS2 | thrombospondin 2 | -0.00662749 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00658525 |
| TNS3 | tensin 3 | -0.00656527 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00656339 |
| ANXA4 | annexin A4 | -0.00655521 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00653572 |
| LY86 | lymphocyte antigen 86 | -0.00652328 |
| SSPN | sarcospan | -0.0065217 |
| PDGFD | platelet derived growth factor D | -0.00651627 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00649888 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00647613 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.00646821 |
| TXNIP | thioredoxin interacting protein | -0.00646737 |
| PCLAF | PCNA clamp associated factor | -0.00646674 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00645291 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.0064505 |
| GPX1 | glutathione peroxidase 1 | -0.00643968 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | -0.00643864 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00641176 |
| FGB | fibrinogen beta chain | -0.00641133 |
| S100A4 | S100 calcium binding protein A4 | -0.00640165 |
| CDO1 | cysteine dioxygenase type 1 | -0.00639966 |
| C1R | complement component 1, r subcomponent | -0.00637428 |
| CD93 | CD93 molecule | -0.0063722 |
| BAD | BCL2-associated agonist of cell death | -0.00634573 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00633604 |
| PLTP | phospholipid transfer protein | -0.00631143 |
| RIN2 | Ras and Rab interactor 2 | -0.00629793 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00628688 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00628007 |
| GPX3 | glutathione peroxidase 3 | -0.00626734 |
| AREG | amphiregulin | -0.00626663 |
| HLA-B | major histocompatibility complex, class I, B | -0.00626495 |
| FBN2 | fibrillin 2 | -0.0062646 |
| GRAMD2B | GRAM domain containing 2B | -0.00625934 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | -0.00625134 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00623764 |
| COL21A1 | collagen, type XXI, alpha 1 | -0.00622502 |
| BEX4 | brain expressed, X-linked 4 | -0.00622274 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00621985 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00618447 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -0.00614769 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00614612 |
| XAF1 | XIAP associated factor 1 | -0.00612952 |
| CFD | complement factor D (adipsin) | -0.0061246 |
| H1-2 | H1.2 linker histone, cluster member | -0.00612185 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00610702 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00610296 |
| GSDME | gasdermin E | -0.00608828 |
| OMD | osteomodulin | -0.00607729 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00607711 |
| APOB | apolipoprotein B | -0.00605068 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0060437 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00603696 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00598929 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00598793 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00598791 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00598522 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | -0.00598361 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00596897 |
| REEP1 | receptor accessory protein 1 | -0.00596546 |
| CTSH | cathepsin H | -0.00595624 |
| TCF4 | transcription factor 4 | -0.005935 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00593493 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00592036 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00590475 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00590114 |
| SEPTIN10 | septin 10 | -0.00589436 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00588029 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00587544 |
| CALD1 | caldesmon 1 | -0.00586792 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0058448 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00582818 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00582052 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00579719 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00579457 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00577114 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00576473 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00576415 |
| IL6R | interleukin 6 receptor | -0.00574982 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00574405 |
| LOXL2 | lysyl oxidase-like 2 | -0.00574268 |
| FGF13 | fibroblast growth factor 13 | -0.00574234 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00573467 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00573191 |
| STC1 | stanniocalcin 1 | -0.00572958 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00572348 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00571667 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00570757 |
| PLSCR4 | phospholipid scramblase 4 | -0.00570457 |
| RAB38 | RAB38, member RAS oncogene family | -0.00570209 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00570011 |
| SESN1 | sestrin 1 | -0.00569031 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.00568364 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00567228 |
