TNF-ALPHA Gene Set
Genes
24 interacting proteins for the TNF-ALPHA drug from theDGIdb Drug Targets 2026 dataset.
| Symbol |
Name |
Standardized Value |
|
CCL25
|
chemokine (C-C motif) ligand 25
|
4.411
|
|
EZR
|
ezrin
|
2.2055
|
|
SLPI
|
secretory leukocyte peptidase inhibitor
|
1.65412
|
|
DEFB4A
|
defensin, beta 4A
|
1.47033
|
|
OSM
|
oncostatin M
|
1.47033
|
|
IFI27
|
interferon, alpha-inducible protein 27
|
1.10275
|
|
IBSP
|
integrin-binding sialoprotein
|
0.8822
|
|
IL17F
|
interleukin 17F
|
0.827062
|
|
MARCKSL1
|
MARCKS-like 1
|
0.735167
|
|
TFAP2A
|
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
|
0.735167
|
|
CCNA2
|
cyclin A2
|
0.630143
|
|
CCL11
|
chemokine (C-C motif) ligand 11
|
0.551375
|
|
COL1A2
|
collagen, type I, alpha 2
|
0.551375
|
|
CTSG
|
cathepsin G
|
0.401
|
|
FCGR2B
|
Fc fragment of IgG, low affinity IIb, receptor (CD32)
|
0.339308
|
|
NR5A1
|
nuclear receptor subfamily 5, group A, member 1
|
0.259471
|
|
GHRL
|
ghrelin/obestatin prepropeptide
|
0.259471
|
|
GNRH1
|
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
|
0.245056
|
|
PTGES
|
prostaglandin E synthase
|
0.22055
|
|
PLA2G1B
|
phospholipase A2, group IB (pancreas)
|
0.157536
|
|
SLC2A4
|
solute carrier family 2 (facilitated glucose transporter), member 4
|
0.131672
|
|
TGM2
|
transglutaminase 2
|
0.102581
|
|
CDK2
|
cyclin-dependent kinase 2
|
0.0364545
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
0.0264132
|
