TNFAIP6 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description tumor necrosis factor, alpha-induced protein 6|The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 7130)
External Link https://ncbi.nlm.nih.gov/gene/7130
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Genes

499 genes differentially expressed following the TNFAIP6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
WT1 Wilms tumor 1 0.014875
PRKCA protein kinase C, alpha 0.0144956
C7 complement component 7 0.0143671
HBB hemoglobin, beta 0.0135443
RNF144A ring finger protein 144A 0.0134949
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0133713
NELL2 NEL-like 2 (chicken) 0.0132773
PLAT plasminogen activator, tissue 0.0130054
BCHE butyrylcholinesterase 0.012979
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.0120495
PBX1 pre-B-cell leukemia homeobox 1 0.0118468
DPYD dihydropyrimidine dehydrogenase 0.0118257
SELL selectin L 0.0117871
GREB1 growth regulation by estrogen in breast cancer 1 0.0115386
LGALS13 lectin, galactoside-binding, soluble, 13 0.0114104
TFF1 trefoil factor 1 0.0112624
RNASE6 ribonuclease, RNase A family, k6 0.0111527
DES desmin 0.0111479
CCR2 chemokine (C-C motif) receptor 2 0.0110765
SRPX sushi-repeat containing protein, X-linked 0.011052
ITK IL2-inducible T-cell kinase 0.0109018
PLN phospholamban 0.0108626
ACP3 acid phosphatase 3 0.0107098
AGR2 anterior gradient 2 0.0106056
CXCL12 chemokine (C-X-C motif) ligand 12 0.0105839
GPR65 G protein-coupled receptor 65 0.0105332
SVIL supervillin 0.0105196
CPVL carboxypeptidase, vitellogenic-like 0.010481
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.0103318
CD36 CD36 molecule (thrombospondin receptor) 0.0102856
S100A12 S100 calcium binding protein A12 0.010252
CADPS2 Ca++-dependent secretion activator 2 0.0101757
COL4A5 collagen, type IV, alpha 5 0.0100983
CCL5 chemokine (C-C motif) ligand 5 0.0100614
DLK1 delta-like 1 homolog (Drosophila) 0.00992697
NKG7 natural killer cell granule protein 7 0.0098951
NIBAN1 niban apoptosis regulator 1 0.00988307
CNN1 calponin 1, basic, smooth muscle 0.00979057
SFRP1 secreted frizzled-related protein 1 0.00973597
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.0095904
MNDA myeloid cell nuclear differentiation antigen 0.00956451
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00955504
MLPH melanophilin 0.00951624
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00940668
ITM2A integral membrane protein 2A 0.00940497
MEIS2 Meis homeobox 2 0.00931551
PDGFC platelet derived growth factor C 0.0093129
PRF1 perforin 1 (pore forming protein) 0.00922189
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00913699
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.00908924
TRIB2 tribbles pseudokinase 2 0.00903251
CST7 cystatin F (leukocystatin) 0.00895865
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00894103
SAMHD1 SAM domain and HD domain 1 0.00875435
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00875254
CD2 CD2 molecule 0.00873855
RRM2 ribonucleotide reductase M2 0.008708
NTS neurotensin 0.00868824
BIRC5 baculoviral IAP repeat containing 5 0.00864694
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00858008
RPS5 ribosomal protein S5 0.0085346
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00848761
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00848478
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00844581
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00833123
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00831905
PHB2 prohibitin 2 0.00831359
BST2 bone marrow stromal cell antigen 2 0.00830609
S100A7 S100 calcium binding protein A7 0.00824487
DCXR dicarbonyl/L-xylulose reductase 0.0082055
TYRP1 tyrosinase-related protein 1 0.00820045
ENO2 enolase 2 (gamma, neuronal) 0.00820012
GZMK granzyme K (granzyme 3; tryptase II) 0.00818947
PCGF2 polycomb group ring finger 2 0.00818653
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.00817956
KAT2B K(lysine) acetyltransferase 2B 0.00815948
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00815034
IL2RB interleukin 2 receptor, beta 0.00814145
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.00812791
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00795442
ELOVL6 ELOVL fatty acid elongase 6 0.00795388
CCNA2 cyclin A2 0.00793101
MEIS1 Meis homeobox 1 0.0079303
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00785705
VCAN versican 0.00784221
PDZK1IP1 PDZK1 interacting protein 1 0.00781009
MTMR11 myotubularin related protein 11 0.0077938
ATXN1 ataxin 1 0.00777199
STON1 stonin 1 0.00776705
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00776126
TMX4 thioredoxin-related transmembrane protein 4 0.00774038
TRMT5 tRNA methyltransferase 5 0.00769552
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.0076876
PSIP1 PC4 and SFRS1 interacting protein 1 0.00767956
CD96 CD96 molecule 0.0076727
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00766691
HBD hemoglobin, delta 0.00766337
NELL1 NEL-like 1 (chicken) 0.00766205
RPL36 ribosomal protein L36 0.00765373
CHN2 chimerin 2 0.00764863
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.00762318
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.007619
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00760648
NUSAP1 nucleolar and spindle associated protein 1 0.00760026
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00758761
CLGN calmegin 0.00757758
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.0075555
KIF4A kinesin family member 4A 0.00754575
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00754571
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.00751874
BTN3A2 butyrophilin, subfamily 3, member A2 0.00750941
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.00750395
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00747298
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00746176
GIMAP6 GTPase, IMAP family member 6 0.00745072
PCYOX1L prenylcysteine oxidase 1 like 0.00743649
SET SET nuclear proto-oncogene 0.00741879
ZNF274 zinc finger protein 274 0.0073809
PTTG1 pituitary tumor-transforming 1 0.00737086
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00736269
LY86 lymphocyte antigen 86 0.00734441
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.00734174
ANXA6 annexin A6 0.00732157
NCAPD3 non-SMC condensin II complex, subunit D3 0.00730174
ARHGAP6 Rho GTPase activating protein 6 0.00730169
CDC20 cell division cycle 20 0.00727444
NQO2 NAD(P)H dehydrogenase, quinone 2 0.0072475
TCEAL2 transcription elongation factor A (SII)-like 2 0.00723663
RHOBTB1 Rho-related BTB domain containing 1 0.00722918
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.00720337
CETN2 centrin, EF-hand protein, 2 0.00719714
CCNG1 cyclin G1 0.00719277
LMOD1 leiomodin 1 (smooth muscle) 0.00717896
CD48 CD48 molecule 0.00717649
DCTD dCMP deaminase 0.00715566
CCNB1 cyclin B1 0.00715146
AHSP alpha hemoglobin stabilizing protein 0.00714517
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00714201
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00712632
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00712213
FYB1 FYN binding protein 1 0.00710877
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.007073
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00706883
ATRAID all-trans retinoic acid-induced differentiation factor 0.00705553
NIPSNAP1 nipsnap homolog 1 (C. elegans) 0.00704463
GYPC glycophorin C (Gerbich blood group) 0.0070413
TARP TCR gamma alternate reading frame protein 0.0070229
SERBP1 SERPINE1 mRNA binding protein 1 0.0070182
RGS1 regulator of G-protein signaling 1 0.00700079
DEK DEK proto-oncogene 0.00699456
ALAS2 5'-aminolevulinate synthase 2 0.00698864
PDZRN3 PDZ domain containing ring finger 3 0.00698191
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00698188
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00696995
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.00696419
EIF4B eukaryotic translation initiation factor 4B 0.0069288
DPYSL3 dihydropyrimidinase-like 3 0.0068996
KIF20A kinesin family member 20A 0.0068959
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00689196
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00685191
TMEM38B transmembrane protein 38B 0.00684167
UBE2C ubiquitin-conjugating enzyme E2C 0.00682188
RALB v-ral simian leukemia viral oncogene homolog B 0.00681189
LYZ lysozyme 0.00679625
TMEM255A transmembrane protein 255A 0.00679523
CD247 CD247 molecule 0.00677156
ASF1B anti-silencing function 1B histone chaperone 0.0067714
PEG3 paternally expressed 3 0.00675281
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00673985
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00673242
FLNA filamin A, alpha 0.00673187
SLC2A4RG SLC2A4 regulator 0.00672854
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.00669245
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00668795
RNASEH2A ribonuclease H2, subunit A 0.00665807
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00664549
PRDX2 peroxiredoxin 2 0.00664373
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00662419
AARS1 alanyl-tRNA synthetase 1 0.0066062
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00660301
AGTR1 angiotensin II receptor, type 1 0.00659199
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00657549
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00657062
MSRB2 methionine sulfoxide reductase B2 0.00656964
CD8A CD8a molecule 0.00656412
AURKB aurora kinase B 0.00655245
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.00650616
TCF21 transcription factor 21 0.00649173
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.00647253
GPR18 G protein-coupled receptor 18 0.00646867
IL18RAP interleukin 18 receptor accessory protein 0.00646497
ABHD10 abhydrolase domain containing 10 0.00644875
GYG1 glycogenin 1 0.00644569
MAL mal, T-cell differentiation protein 0.00644447
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00642729
LGALS1 lectin, galactoside-binding, soluble, 1 0.00642011
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.0064131
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 0.00641006
LMNB2 lamin B2 0.00639125
GIMAP4 GTPase, IMAP family member 4 0.00635281
BRCA1 breast cancer 1, early onset 0.00634345
ALDOC aldolase C, fructose-bisphosphate 0.00633508
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00631914
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.00631634
FOXM1 forkhead box M1 0.00629473
CLEC7A C-type lectin domain family 7, member A 0.0062935
PRKCQ protein kinase C, theta 0.00628977
EXTL2 exostosin-like glycosyltransferase 2 0.00628136
TPX2 TPX2, microtubule-associated 0.00627876
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.00625198
TM7SF2 transmembrane 7 superfamily member 2 0.0062382
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.00623799
TLR4 toll-like receptor 4 0.00623677
PCP4 Purkinje cell protein 4 0.00622254
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.00621977
HMGN4 high mobility group nucleosomal binding domain 4 0.00621152
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00620005
HOXB6 homeobox B6 0.00619532
PRC1 protein regulator of cytokinesis 1 0.00618522
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.00617751
KRT1 keratin 1, type II 0.00617091
XPO7 exportin 7 0.00616797
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00616206
PMEL premelanosome protein 0.00616082
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 0.00615356
RHOT1 ras homolog family member T1 0.00614812
NEK2 NIMA-related kinase 2 0.00614329
CALML5 calmodulin-like 5 0.00614266
PUM2 pumilio RNA-binding family member 2 0.00613825
CASC3 cancer susceptibility candidate 3 0.00613306
KANK2 KN motif and ankyrin repeat domains 2 0.00611903
PRKD1 protein kinase D1 0.0061174
TBC1D4 TBC1 domain family, member 4 0.0061124
LDB3 LIM domain binding 3 0.00610765
FBXO5 F-box protein 5 0.00609987
NID1 nidogen 1 0.00609379
CTSW cathepsin W 0.00609059
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00608567
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00608033
TMEM14B transmembrane protein 14B 0.00607886
TRIM14 tripartite motif containing 14 0.00607141
GAS1 growth arrest-specific 1 0.00607106
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00606257
VLDLR very low density lipoprotein receptor 0.00605974
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.00604602
GCH1 GTP cyclohydrolase 1 0.006018
P4HB prolyl 4-hydroxylase, beta polypeptide 0.00601053
TESC tescalcin 0.00600678
ZFPM2 zinc finger protein, FOG family member 2 0.00599884
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00599616

decreased expression

Symbol Name Standardized Value
AKR1C2 aldo-keto reductase family 1, member C2 -0.0184104
SLC38A1 solute carrier family 38, member 1 -0.0173139
AKR1C1 aldo-keto reductase family 1, member C1 -0.0170976
AKR1C3 aldo-keto reductase family 1, member C3 -0.0170025
ADIRF adipogenesis regulatory factor -0.0162404
CD9 CD9 molecule -0.015694
HSPA1A heat shock 70kDa protein 1A -0.0154054
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0147096
ACKR3 atypical chemokine receptor 3 -0.0146274
CRYAB crystallin, alpha B -0.0144764
FN1 fibronectin 1 -0.014203
KRT14 keratin 14, type I -0.0140015
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.0139364
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0139128
EMP1 epithelial membrane protein 1 -0.0135001
H1-2 H1.2 linker histone, cluster member -0.013131
MAP7 microtubule-associated protein 7 -0.0130553
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0127775
KLF6 Kruppel-like factor 6 -0.012501
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.0123481
HMOX1 heme oxygenase 1 -0.0121536
RRAGC Ras-related GTP binding C -0.0121076
PERP PERP, TP53 apoptosis effector -0.0120056
CA12 carbonic anhydrase XII -0.0117862
CCN2 cellular communication network factor 2 -0.0116962
SLPI secretory leukocyte peptidase inhibitor -0.0116775
EZR ezrin -0.0116552
CLEC3B C-type lectin domain family 3, member B -0.0113668
MT1E metallothionein 1E -0.0113502
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.0113096
PELI1 pellino E3 ubiquitin protein ligase 1 -0.0112758
KRT17 keratin 17, type I -0.0112461
KRAS Kirsten rat sarcoma viral oncogene homolog -0.0111734
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0111341
HTRA1 HtrA serine peptidase 1 -0.0111104
CP ceruloplasmin (ferroxidase) -0.0109563
IL1R1 interleukin 1 receptor, type I -0.0109263
STC2 stanniocalcin 2 -0.0107524
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.010637
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.0105262
GPNMB glycoprotein (transmembrane) nmb -0.0105146
KLF9 Kruppel-like factor 9 -0.0104707
FNDC3B fibronectin type III domain containing 3B -0.0104062
RGCC regulator of cell cycle -0.0103638
BMP2 bone morphogenetic protein 2 -0.0103016
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.0102747
KLF5 Kruppel-like factor 5 (intestinal) -0.0102474
IFI27 interferon, alpha-inducible protein 27 -0.0102347
SCRG1 stimulator of chondrogenesis 1 -0.0101811
MIR22HG MIR22 host gene -0.0101396
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0100555
ATF3 activating transcription factor 3 -0.00999402
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.00995686
IGF1R insulin-like growth factor 1 receptor -0.00982006
CSRP2 cysteine and glycine-rich protein 2 -0.00979102
CPM carboxypeptidase M -0.00975328
TMEM176B transmembrane protein 176B -0.00975172
FTH1 ferritin, heavy polypeptide 1 -0.00973032
COMP cartilage oligomeric matrix protein -0.00967373
SEPP1 selenoprotein P, plasma, 1 -0.00966236
FADS3 fatty acid desaturase 3 -0.009604
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00954172
NNMT nicotinamide N-methyltransferase -0.00952039
MGLL monoglyceride lipase -0.00951364
EFNA1 ephrin-A1 -0.00948149
BRD4 bromodomain containing 4 -0.00947297
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00946523
SOWAHC sosondowah ankyrin repeat domain family member C -0.00943779
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00939802
KRT23 keratin 23, type I -0.00933349
MET MET proto-oncogene, receptor tyrosine kinase -0.00929336
BLNK B-cell linker -0.00926976
RND3 Rho family GTPase 3 -0.00918948
CA2 carbonic anhydrase II -0.00909306
LEPROT leptin receptor overlapping transcript -0.00906029
WSB1 WD repeat and SOCS box containing 1 -0.00894305
WASL Wiskott-Aldrich syndrome-like -0.00886215
ASS1 argininosuccinate synthase 1 -0.00879767
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00876959
GOLIM4 golgi integral membrane protein 4 -0.00873792
EIF5B eukaryotic translation initiation factor 5B -0.00872363
SOX4 SRY (sex determining region Y)-box 4 -0.00871296
BIK BCL2-interacting killer (apoptosis-inducing) -0.00869444
BRD2 bromodomain containing 2 -0.00869397
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.0086629
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00864935
ELN elastin -0.00864487
TSC22D2 TSC22 domain family, member 2 -0.00863862
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00861696
FGFR3 fibroblast growth factor receptor 3 -0.00857009
HIST1H2BD histone cluster 1, H2bd -0.00855795
MID1 midline 1 -0.00853087
BTG1 B-cell translocation gene 1, anti-proliferative -0.00847501
TPD52 tumor protein D52 -0.00847031
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00841551
MYO1B myosin IB -0.00838383
SIK1 salt-inducible kinase 1 -0.0083796
RYBP RING1 and YY1 binding protein -0.00836942
IPO13 importin 13 -0.0083647
SDC2 syndecan 2 -0.00835788
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00831687
FOXD1 forkhead box D1 -0.00828754
EIF6 eukaryotic translation initiation factor 6 -0.00825925
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00825519
SCGB2A1 secretoglobin, family 2A, member 1 -0.00822669
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00821809
HSPA2 heat shock 70kDa protein 2 -0.00818315
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00817844
MYO6 myosin VI -0.00815438
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.00815215
LITAF lipopolysaccharide-induced TNF factor -0.00814282
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00814229
ZNF423 zinc finger protein 423 -0.00813424
RAB9A RAB9A, member RAS oncogene family -0.00812404
SGK1 serum/glucocorticoid regulated kinase 1 -0.0081179
MT1X metallothionein 1X -0.00811368
FOXC1 forkhead box C1 -0.00808952
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00808243
SCGB2A2 secretoglobin, family 2A, member 2 -0.00807912
CLCA4 chloride channel accessory 4 -0.00806203
PXDC1 PX domain containing 1 -0.0080197
PHACTR2 phosphatase and actin regulator 2 -0.00801869
KIF5B kinesin family member 5B -0.00799582
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.00799327
PRSS23 protease, serine, 23 -0.00797788
BCL3 B-cell CLL/lymphoma 3 -0.00797566
FBXO2 F-box protein 2 -0.00797253
RTN4 reticulon 4 -0.00795207
LPAR1 lysophosphatidic acid receptor 1 -0.00792471
EIF5A eukaryotic translation initiation factor 5A -0.00787839
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00785615
LIMS1 LIM and senescent cell antigen-like domains 1 -0.00781159
KLF7 Kruppel-like factor 7 (ubiquitous) -0.00780219
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00777685
CTSZ cathepsin Z -0.00775838
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.0077374
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00770786
ANKRD12 ankyrin repeat domain 12 -0.00766181
ARMCX3 armadillo repeat containing, X-linked 3 -0.00764407
ADM adrenomedullin -0.00764384
MPC2 mitochondrial pyruvate carrier 2 -0.00760697
RETREG1 reticulophagy regulator 1 -0.00759529
TPD52L1 tumor protein D52-like 1 -0.00758413
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.00758383
HIST1H2BK histone cluster 1, H2bk -0.00758095
SIRT3 sirtuin 3 -0.00757844
TMBIM1 transmembrane BAX inhibitor motif containing 1 -0.00757533
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00755489
HIST1H2AC histone cluster 1, H2ac -0.00755128
TGFBI transforming growth factor, beta-induced, 68kDa -0.00752055
NOTCH1 notch 1 -0.00751937
AOC1 amine oxidase, copper containing 1 -0.00751488
BCAS1 breast carcinoma amplified sequence 1 -0.00751077
AKIRIN1 akirin 1 -0.00747889
TCF4 transcription factor 4 -0.0074763
TRIM29 tripartite motif containing 29 -0.00747036
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00746228
NDRG1 N-myc downstream regulated 1 -0.00745507
SDC4 syndecan 4 -0.00742412
INSR insulin receptor -0.00741266
KLHL24 kelch-like family member 24 -0.00739147
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00737663
TUBA4A tubulin, alpha 4a -0.00736435
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -0.0073523
THBS4 thrombospondin 4 -0.00734446
SPATA20 spermatogenesis associated 20 -0.00728642
ANO10 anoctamin 10 -0.00727288
SPAG9 sperm associated antigen 9 -0.00726329
MBD2 methyl-CpG binding domain protein 2 -0.00724117
RIDA reactive intermediate imine deaminase A homolog -0.00723749
ABHD3 abhydrolase domain containing 3 -0.00722499
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00721431
G0S2 G0/G1 switch 2 -0.00721199
MMP10 matrix metallopeptidase 10 -0.00718972
SQSTM1 sequestosome 1 -0.0071798
PLPP3 phospholipid phosphatase 3 -0.00717348
SENP6 SUMO1/sentrin specific peptidase 6 -0.00715522
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00714046
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00712878
ZBTB35 zinc finger and BTB domain containing 35 -0.00711817
MCM2 minichromosome maintenance complex component 2 -0.0071179
SEC62 SEC62 homolog (S. cerevisiae) -0.0071023
KRT5 keratin 5, type II -0.00709089
DAPK1 death-associated protein kinase 1 -0.00706436
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.00706003
CHP1 calcineurin-like EF-hand protein 1 -0.00704699
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.00703465
PTK2B protein tyrosine kinase 2 beta -0.00702168
IGF2R insulin-like growth factor 2 receptor -0.0070055
ALAS1 5'-aminolevulinate synthase 1 -0.00699715
EFHD1 EF-hand domain family, member D1 -0.00698519
HSPB8 heat shock 22kDa protein 8 -0.00698086
VAMP8 vesicle-associated membrane protein 8 -0.006954
CCNG2 cyclin G2 -0.00694581
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.0069424
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00693877
ANKRD11 ankyrin repeat domain 11 -0.00691758
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00691393
AREG amphiregulin -0.00690656
OLFML2A olfactomedin-like 2A -0.00688713
MT1M metallothionein 1M -0.00685563
ANGPTL4 angiopoietin-like 4 -0.00685513
MYO1E myosin IE -0.00685371
IER5 immediate early response 5 -0.00684787
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00682995
KLF13 Kruppel-like factor 13 -0.00681502
EDN1 endothelin 1 -0.0067965
ECM1 extracellular matrix protein 1 -0.00678842
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00678492
OLFML2B olfactomedin-like 2B -0.00677876
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00675297
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -0.00673364
CUX1 cut-like homeobox 1 -0.00671747
PCDH9 protocadherin 9 -0.0067038
CLU clusterin -0.00670195
DYNLL1 dynein, light chain, LC8-type 1 -0.00668151
ETNPPL ethanolamine-phosphate phospho-lyase -0.00667734
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.00666391
USP47 ubiquitin specific peptidase 47 -0.0066502
PIGR polymeric immunoglobulin receptor -0.0066435
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00663868
HK2 hexokinase 2 -0.00661969
MED13 mediator complex subunit 13 -0.00661452
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -0.0066142
ISG20 interferon stimulated exonuclease gene 20kDa -0.00660861
TPSAB1 tryptase alpha/beta 1 -0.00659875
MSX1 msh homeobox 1 -0.00659793
PROM1 prominin 1 -0.00659398
FBLN2 fibulin 2 -0.00658953
DUSP5 dual specificity phosphatase 5 -0.00653738
ANGPT1 angiopoietin 1 -0.00652638
FAM107A family with sequence similarity 107, member A -0.00652496
SPP1 secreted phosphoprotein 1 -0.00652191
NRCAM neuronal cell adhesion molecule -0.00649096
AUTS2 autism susceptibility candidate 2 -0.0064898
FHL2 four and a half LIM domains 2 -0.00648205
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -0.00648062
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00647267
CDO1 cysteine dioxygenase type 1 -0.0064679
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00645435
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00641705
EPS8L2 EPS8-like 2 -0.00641176
ZG16 zymogen granule protein 16 -0.00639448
HOXC10 homeobox C10 -0.00639126
ZNF91 zinc finger protein 91 -0.00639101
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0063817
RRBP1 ribosome binding protein 1 -0.00636929
SASH1 SAM and SH3 domain containing 1 -0.00632392
RHOB ras homolog family member B -0.00632334