TNFRSF11A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description tumor necrosis factor receptor superfamily, member 11a, NFKB activator|The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 8792)
External Link https://ncbi.nlm.nih.gov/gene/8792
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Genes

498 genes differentially expressed following the TNFRSF11A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PROM1 prominin 1 0.0132684
KRT7 keratin 7, type II 0.011951
CRYAB crystallin, alpha B 0.0110229
DYNLL1 dynein, light chain, LC8-type 1 0.0104643
GNAS GNAS complex locus 0.0104343
S100A8 S100 calcium binding protein A8 0.0103028
S100A2 S100 calcium binding protein A2 0.0101645
GPNMB glycoprotein (transmembrane) nmb 0.0100903
TRIM29 tripartite motif containing 29 0.0100262
CXCL14 chemokine (C-X-C motif) ligand 14 0.0100065
LIMCH1 LIM and calponin homology domains 1 0.00974977
SMAD7 SMAD family member 7 0.0095141
IPO13 importin 13 0.00950306
MAGEA3 melanoma antigen family A3 0.00943371
CSRP2 cysteine and glycine-rich protein 2 0.00936934
IL1RN interleukin 1 receptor antagonist 0.00924652
BGN biglycan 0.00913095
CSTA cystatin A (stefin A) 0.00908131
GPX2 glutathione peroxidase 2 0.00905951
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00892234
CXCL8 chemokine (C-X-C motif) ligand 8 0.00882517
AMIGO2 adhesion molecule with Ig-like domain 2 0.00881712
CTSD cathepsin D 0.00876988
KRT14 keratin 14, type I 0.00863613
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00858361
HTRA1 HtrA serine peptidase 1 0.00857606
LYPD3 LY6/PLAUR domain containing 3 0.00853056
SNX11 sorting nexin 11 0.00842168
GLS glutaminase 0.00838253
TIMP3 TIMP metallopeptidase inhibitor 3 0.00831697
PSCA prostate stem cell antigen 0.00831076
DEPTOR DEP domain containing MTOR-interacting protein 0.00826911
HOPX HOP homeobox 0.00822167
GOLGA8H golgin A8 family, member H 0.00818455
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00811938
TACSTD2 tumor-associated calcium signal transducer 2 0.00811067
PTK2B protein tyrosine kinase 2 beta 0.00805402
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00801134
SGK1 serum/glucocorticoid regulated kinase 1 0.00797079
PERP PERP, TP53 apoptosis effector 0.00797071
CA12 carbonic anhydrase XII 0.00791538
MGLL monoglyceride lipase 0.00787453
JMJD6 jumonji domain containing 6 0.00785612
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.0077926
ANXA10 annexin A10 0.00778226
S100P S100 calcium binding protein P 0.00777375
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00777107
RRAGD Ras-related GTP binding D 0.00776147
SPRR3 small proline-rich protein 3 0.00772899
ACKR3 atypical chemokine receptor 3 0.00769376
SFN stratifin 0.00768513
KRT19 keratin 19, type I 0.00765365
MN1 meningioma (disrupted in balanced translocation) 1 0.00761733
GPX3 glutathione peroxidase 3 0.00759689
MPC2 mitochondrial pyruvate carrier 2 0.00759421
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00758799
GREM1 gremlin 1, DAN family BMP antagonist 0.00758536
ADIRF adipogenesis regulatory factor 0.00750684
KRT23 keratin 23, type I 0.00749435
S100A9 S100 calcium binding protein A9 0.00748306
LXN latexin 0.00748266
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00742427
KRT13 keratin 13, type I 0.00736883
RPS27L ribosomal protein S27-like 0.00735326
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00732943
SPRR1B small proline-rich protein 1B 0.00731505
INHBA inhibin, beta A 0.0072813
S100A11 S100 calcium binding protein A11 0.00727579
TSPAN13 tetraspanin 13 0.00726775
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 0.00719219
STK26 serine/threonine protein kinase 26 0.00718241
BICC1 BicC family RNA binding protein 1 0.00717436
MET MET proto-oncogene, receptor tyrosine kinase 0.00709391
PSD3 pleckstrin and Sec7 domain containing 3 0.00709195
ARMCX3 armadillo repeat containing, X-linked 3 0.00706605
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00704382
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 0.00704246
LAT2 linker for activation of T cells family, member 2 0.00703459
TMEM47 transmembrane protein 47 0.0070139
CLDN10 claudin 10 0.00696311
UPK1B uroplakin 1B 0.00691211
ELN elastin 0.00687464
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00685182
CLEC3B C-type lectin domain family 3, member B 0.00682986
PLAGL1 pleiomorphic adenoma gene-like 1 0.00681858
SLPI secretory leukocyte peptidase inhibitor 0.00681225
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00678621
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00676999
KRT6A keratin 6A, type II 0.00674035
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00672205
KLF2 Kruppel-like factor 2 0.00671406
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0067036
PLAAT3 phospholipase A and acyltransferase 3 0.00663066
COX17 COX17 cytochrome c oxidase copper chaperone 0.00662019
THBS2 thrombospondin 2 0.0065908
MID1 midline 1 0.00658561
WASF1 WAS protein family, member 1 0.00657326
ZDHHC6 zinc finger, DHHC-type containing 6 0.0065632
LOC283683 uncharacterized LOC283683 0.00654274
NOTCH1 notch 1 0.00648207
ELF4 E74-like factor 4 (ets domain transcription factor) 0.0064583
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00645151
VAMP8 vesicle-associated membrane protein 8 0.00644154
HPGDS hematopoietic prostaglandin D synthase 0.00643442
MX1 MX dynamin-like GTPase 1 0.00640064
AQP3 aquaporin 3 (Gill blood group) 0.00639782
GPX7 glutathione peroxidase 7 0.00634022
SDC2 syndecan 2 0.00633998
PIP prolactin-induced protein 0.00633272
HEATR1 HEAT repeat containing 1 0.00632128
SC5D sterol-C5-desaturase 0.00631496
HMOX1 heme oxygenase 1 0.00630421
FSCN1 fascin actin-bundling protein 1 0.0062546
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.0062515
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00622363
OGFRL1 opioid growth factor receptor-like 1 0.00620742
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00615062
LACTB2 lactamase, beta 2 0.00607764
IER5 immediate early response 5 0.00606998
PLK2 polo-like kinase 2 0.00606082
CD37 CD37 molecule 0.00604678
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00602735
MAST4 microtubule associated serine/threonine kinase family member 4 0.006018
MFAP5 microfibrillar associated protein 5 0.00599511
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00598691
TUBA4A tubulin, alpha 4a 0.00596503
TSPO translocator protein (18kDa) 0.00596487
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00595498
RAB9A RAB9A, member RAS oncogene family 0.00588351
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00587952
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00587571
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00587276
SSH3 slingshot protein phosphatase 3 0.00582502
LAMP5 lysosomal-associated membrane protein family, member 5 0.00581709
QKI QKI, KH domain containing, RNA binding 0.00578117
ATP5MG ATP synthase membrane subunit g 0.00576449
RND3 Rho family GTPase 3 0.00574354
BBX bobby sox homolog (Drosophila) 0.00573975
GPR137B G protein-coupled receptor 137B 0.00573287
SMC1A structural maintenance of chromosomes 1A 0.00571353
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00570289
VCAM1 vascular cell adhesion molecule 1 0.00569881
PHYH phytanoyl-CoA 2-hydroxylase 0.00569057
NNMT nicotinamide N-methyltransferase 0.00568878
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00568195
AHR aryl hydrocarbon receptor 0.00567078
TDG thymine-DNA glycosylase 0.00566864
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00563667
TTC9 tetratricopeptide repeat domain 9 0.00562537
FGFR3 fibroblast growth factor receptor 3 0.00561372
CALB1 calbindin 1, 28kDa 0.0056021
ITGB4 integrin, beta 4 0.00560174
APOC1 apolipoprotein C-I 0.00560162
RHOD ras homolog family member D 0.00559755
SIK1 salt-inducible kinase 1 0.00559391
COMT catechol-O-methyltransferase 0.00559086
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00558052
CHIC2 cysteine-rich hydrophobic domain 2 0.00556626
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.00553208
PMP22 peripheral myelin protein 22 0.00552126
PCDH17 protocadherin 17 0.005512
CYBA cytochrome b-245, alpha polypeptide 0.00551177
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0055091
SPRR1A small proline-rich protein 1A 0.00550688
DUSP2 dual specificity phosphatase 2 0.00548971
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00548948
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00547621
ZBED2 zinc finger, BED-type containing 2 0.00547196
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00546263
TGFA transforming growth factor, alpha 0.00545165
TFPI2 tissue factor pathway inhibitor 2 0.0054411
ICAM2 intercellular adhesion molecule 2 0.00540768
COMP cartilage oligomeric matrix protein 0.00540425
ACTN4 actinin, alpha 4 0.00540016
ATP5F1E ATP synthase F1 subunit epsilon 0.00539757
XYLT1 xylosyltransferase I 0.00539213
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 0.00537646
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00537615
SDC1 syndecan 1 0.00536816
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00536266
LRRC32 leucine rich repeat containing 32 0.00535766
MXRA5 matrix-remodelling associated 5 0.00533661
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 0.00532304
LYPLA1 lysophospholipase I 0.00530918
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.00530159
KRT17 keratin 17, type I 0.00529218
SDC4 syndecan 4 0.00528755
TSC22D2 TSC22 domain family, member 2 0.00528042
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00527564
KIAA0040 KIAA0040 0.00526087
CNOT7 CCR4-NOT transcription complex, subunit 7 0.0052553
PLTP phospholipid transfer protein 0.00525505
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00523961
HACD2 3-hydroxyacyl-CoA dehydratase 2 0.00521314
CCNA2 cyclin A2 0.00520504
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00519709
PDLIM5 PDZ and LIM domain 5 0.00518935
PENK proenkephalin 0.0051846
LYZ lysozyme 0.00518293
LTBP2 latent transforming growth factor beta binding protein 2 0.00517912
ADGRF5 adhesion G protein-coupled receptor F5 0.00516957
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00515407
HAUS3 HAUS augmin-like complex, subunit 3 0.00514782
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.00514477
CTSW cathepsin W 0.00513594
SPON2 spondin 2, extracellular matrix protein 0.00513291
EHD3 EH-domain containing 3 0.00511869
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.00510898
HMGN3 high mobility group nucleosomal binding domain 3 0.00510349
KRT6B keratin 6B, type II 0.00507905
PXDC1 PX domain containing 1 0.00505525
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00503798
TRAPPC6A trafficking protein particle complex 6A 0.00503281
TUFT1 tuftelin 1 0.00503279
WASL Wiskott-Aldrich syndrome-like 0.00503034
JUP junction plakoglobin 0.00502771
ARMCX1 armadillo repeat containing, X-linked 1 0.00502708
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00502351
AKAP8 A kinase (PRKA) anchor protein 8 0.00502278
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00502104
RNF6 ring finger protein (C3H2C3 type) 6 0.00501574
SNF8 SNF8, ESCRT-II complex subunit 0.00501129
FTH1 ferritin, heavy polypeptide 1 0.00500826
TPD52L1 tumor protein D52-like 1 0.00498876
ISYNA1 inositol-3-phosphate synthase 1 0.00498318
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.00497836
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00496997
GCHFR GTP cyclohydrolase I feedback regulator 0.00493711
RHOBTB1 Rho-related BTB domain containing 1 0.00492753
LAD1 ladinin 1 0.00491538
FNDC3B fibronectin type III domain containing 3B 0.00490571
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 0.00490531
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00490092
MYD88 myeloid differentiation primary response 88 0.00487616
FRZB frizzled-related protein 0.00487276
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.0048712
ALOX5 arachidonate 5-lipoxygenase 0.00486617
JPT1 Jupiter microtubule associated homolog 1 0.00485958
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.0048447
PLXND1 plexin D1 0.00483927
CYB5A cytochrome b5 type A (microsomal) 0.00482309
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.00481659
SLIT1 slit homolog 1 (Drosophila) 0.00479711
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00479385
NME5 NME/NM23 family member 5 0.00477877
EYA1 EYA transcriptional coactivator and phosphatase 1 0.00477079
TM4SF4 transmembrane 4 L six family member 4 0.00476037
XAF1 XIAP associated factor 1 0.00475015

decreased expression

Symbol Name Standardized Value
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0125106
SIRT3 sirtuin 3 -0.0115464
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00983112
GREB1 growth regulation by estrogen in breast cancer 1 -0.00955644
CD9 CD9 molecule -0.00901083
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00887019
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00877054
SYNGR3 synaptogyrin 3 -0.00870531
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00859472
KIF1B kinesin family member 1B -0.00853167
NELL2 NEL-like 2 (chicken) -0.00813931
TUBB2A tubulin, beta 2A class IIa -0.00807382
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00805188
ENO2 enolase 2 (gamma, neuronal) -0.00803711
TSPAN8 tetraspanin 8 -0.00798423
IL27RA interleukin 27 receptor, alpha -0.00778647
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00778382
COL1A2 collagen, type I, alpha 2 -0.00760765
GAB2 GRB2-associated binding protein 2 -0.00729245
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00728875
NEFH neurofilament, heavy polypeptide -0.00723531
SPON1 spondin 1, extracellular matrix protein -0.00701641
CLCA1 chloride channel accessory 1 -0.00701626
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00697839
ACOT7 acyl-CoA thioesterase 7 -0.00695872
ACP3 acid phosphatase 3 -0.00685074
CA2 carbonic anhydrase II -0.00684251
WNT5A wingless-type MMTV integration site family, member 5A -0.00682316
APOA1 apolipoprotein A-I -0.0067976
RAD23B RAD23 homolog B (S. cerevisiae) -0.00677165
OLFM1 olfactomedin 1 -0.00674675
TM9SF3 transmembrane 9 superfamily member 3 -0.00671939
APOC3 apolipoprotein C-III -0.00666443
PGD phosphogluconate dehydrogenase -0.0066425
PSAT1 phosphoserine aminotransferase 1 -0.00664086
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00661104
GANAB glucosidase, alpha; neutral AB -0.0065996
NCAPD2 non-SMC condensin I complex, subunit D2 -0.00656697
CAVIN2 caveolae associated protein 2 -0.00655436
AMDHD2 amidohydrolase domain containing 2 -0.00651744
SYT1 synaptotagmin I -0.00649232
KIF5C kinesin family member 5C -0.00647404
ANXA2 annexin A2 -0.00640737
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00640579
COL4A5 collagen, type IV, alpha 5 -0.00635261
BEX1 brain expressed, X-linked 1 -0.00633456
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00633256
PRKCA protein kinase C, alpha -0.00632501
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00630955
CD1D CD1d molecule -0.00627916
PKP2 plakophilin 2 -0.00625199
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.0062217
OGN osteoglycin -0.00621694
RSL1D1 ribosomal L1 domain containing 1 -0.00619941
ANO10 anoctamin 10 -0.00617139
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00616544
MMP12 matrix metallopeptidase 12 -0.00612318
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.00611151
SI sucrase-isomaltase (alpha-glucosidase) -0.00607652
SEPP1 selenoprotein P, plasma, 1 -0.0060715
ABHD6 abhydrolase domain containing 6 -0.00606782
L1CAM L1 cell adhesion molecule -0.00602916
DPYSL3 dihydropyrimidinase-like 3 -0.00601958
GLO1 glyoxalase I -0.00601647
SORD sorbitol dehydrogenase -0.00600538
APOA2 apolipoprotein A-II -0.00594661
MEX3D mex-3 RNA binding family member D -0.00591766
TMC5 transmembrane channel-like 5 -0.00591591
CLEC2B C-type lectin domain family 2, member B -0.005904
ANXA6 annexin A6 -0.00589809
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.00585143
NVL nuclear VCP-like -0.00584122
GPC3 glypican 3 -0.0058391
SVIL supervillin -0.0058176
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00579203
PTCH1 patched 1 -0.00578054
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.00575304
PHB2 prohibitin 2 -0.00574012
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00572258
HIST3H2A histone cluster 3, H2a -0.00571533
DCTN4 dynactin 4 (p62) -0.0057059
SRR serine racemase -0.00567663
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -0.00565099
TMEM135 transmembrane protein 135 -0.00564293
KRT18 keratin 18, type I -0.00563089
FAM198B family with sequence similarity 198, member B -0.00562609
ARG2 arginase 2 -0.00559227
LOC730101 uncharacterized LOC730101 -0.00559222
SRSF1 serine/arginine-rich splicing factor 1 -0.00558526
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.00557284
APOB apolipoprotein B -0.00555971
CD8A CD8a molecule -0.00554367
LRRC17 leucine rich repeat containing 17 -0.00553431
MAPK1 mitogen-activated protein kinase 1 -0.00552813
CD1E CD1e molecule -0.00552242
AARS1 alanyl-tRNA synthetase 1 -0.00550438
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -0.00549192
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.00548367
MMP3 matrix metallopeptidase 3 -0.00546569
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00546037
NPTXR neuronal pentraxin receptor -0.00545194
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.00543466
STMN2 stathmin 2 -0.00542794
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.00540999
CNTNAP2 contactin associated protein-like 2 -0.00540353
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00539731
IFITM1 interferon induced transmembrane protein 1 -0.00538968
XK X-linked Kx blood group -0.00537927
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00536449
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00536327
CASP8 caspase 8, apoptosis-related cysteine peptidase -0.00528419
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -0.00527675
CAV1 caveolin 1, caveolae protein, 22kDa -0.0052668
IFI16 interferon, gamma-inducible protein 16 -0.00526373
CDK14 cyclin-dependent kinase 14 -0.00523694
CALCA calcitonin-related polypeptide alpha -0.00523595
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.005235
ECI2 enoyl-CoA delta isomerase 2 -0.00523362
SET SET nuclear proto-oncogene -0.00522051
SLC35E2B solute carrier family 35, member E2B -0.00521862
KIF20A kinesin family member 20A -0.00521325
FGF13 fibroblast growth factor 13 -0.00518577
PER3 period circadian clock 3 -0.00517858
HOXB6 homeobox B6 -0.00516559
ODC1 ornithine decarboxylase 1 -0.00516416
TAL1 T-cell acute lymphocytic leukemia 1 -0.00515981
AHNAK AHNAK nucleoprotein -0.00514419
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00514288
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00513194
IARS1 isoleucyl-tRNA synthetase 1 -0.00512194
COL4A2 collagen, type IV, alpha 2 -0.00511757
ADGRE1 adhesion G protein-coupled receptor E1 -0.00509863
TRIM36 tripartite motif containing 36 -0.00508862
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) -0.00508622
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) -0.00507097
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -0.00507036
GDI2 GDP dissociation inhibitor 2 -0.00506427
TLR4 toll-like receptor 4 -0.00505345
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00505209
PCLO piccolo presynaptic cytomatrix protein -0.00500083
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -0.00498464
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -0.00496812
SHTN1 shootin 1 -0.00496401
H1-10 H1.10 linker histone -0.0049578
PAGE4 P antigen family, member 4 (prostate associated) -0.00494401
FABP1 fatty acid binding protein 1, liver -0.00494393
ARG1 arginase 1 -0.00492157
WARS1 tryptophanyl-tRNA synthetase 1 -0.00491218
CDCA3 cell division cycle associated 3 -0.00490575
PEX5 peroxisomal biogenesis factor 5 -0.00489845
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00489075
EXOC5 exocyst complex component 5 -0.0048829
KLK3 kallikrein-related peptidase 3 -0.00486609
TYRO3 TYRO3 protein tyrosine kinase -0.00486018
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -0.00485637
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.0048328
RMI1 RecQ mediated genome instability 1 -0.00483189
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -0.00482262
CBS cystathionine-beta-synthase -0.00481572
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00480258
SARS1 seryl-tRNA synthetase 1 -0.00479953
CANX calnexin -0.00479829
C9ORF40 chromosome 9 open reading frame 40 -0.00479709
GAB1 GRB2-associated binding protein 1 -0.00479266
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00479256
SCARB2 scavenger receptor class B, member 2 -0.00478876
TEAD4 TEA domain family member 4 -0.0047858
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.00475225
RGS10 regulator of G-protein signaling 10 -0.00473577
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00473439
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00473377
XPO7 exportin 7 -0.00473223
NDC1 NDC1 transmembrane nucleoporin -0.0047215
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00471723
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.00470985
A2M alpha-2-macroglobulin -0.00470846
MMP1 matrix metallopeptidase 1 -0.004702
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.00469599
TPX2 TPX2, microtubule-associated -0.00468464
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00468279
FBXW2 F-box and WD repeat domain containing 2 -0.00468125
SPARCL1 SPARC-like 1 (hevin) -0.0046804
CRELD2 cysteine-rich with EGF-like domains 2 -0.00467941
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -0.00467362
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.00467318
NMT2 N-myristoyltransferase 2 -0.0046679
CETN2 centrin, EF-hand protein, 2 -0.00466176
CYBRD1 cytochrome b reductase 1 -0.00466175
RTN1 reticulon 1 -0.00465745
CD1B CD1b molecule -0.00464957
RAB20 RAB20, member RAS oncogene family -0.00464793
EPHB2 EPH receptor B2 -0.00462731
ADAM22 ADAM metallopeptidase domain 22 -0.00462503
MYOF myoferlin -0.00461873
SOX11 SRY (sex determining region Y)-box 11 -0.00461184
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 -0.00460098
CD36 CD36 molecule (thrombospondin receptor) -0.00457544
MRPS16 mitochondrial ribosomal protein S16 -0.00456623
HIST1H2AC histone cluster 1, H2ac -0.00456456
NFE2L3 nuclear factor, erythroid 2-like 3 -0.00453956
ITGA6 integrin, alpha 6 -0.00453899
FGR FGR proto-oncogene, Src family tyrosine kinase -0.00453856
HLA-DOB major histocompatibility complex, class II, DO beta -0.00453426
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00453215
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00453046
GOLM1 golgi membrane protein 1 -0.00451414
CFB complement factor B -0.00450338
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00448957
ZG16 zymogen granule protein 16 -0.00448115
PSRC1 proline/serine-rich coiled-coil 1 -0.00448108
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00447592
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -0.00447071
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00446481
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.00446283
GBP1 guanylate binding protein 1, interferon-inducible -0.00446201
FZD5 frizzled class receptor 5 -0.00445885
CCK cholecystokinin -0.00445386
GLG1 golgi glycoprotein 1 -0.00444387
NID1 nidogen 1 -0.00444211
CCKBR cholecystokinin B receptor -0.00442188
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -0.00441842
PEG3 paternally expressed 3 -0.00441253
KLK2 kallikrein-related peptidase 2 -0.00439794
POT1 protection of telomeres 1 -0.00439671
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00439445
FSD1 fibronectin type III and SPRY domain containing 1 -0.00438441
CPE carboxypeptidase E -0.00437858
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -0.00437783
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00436472
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.00436346
TFDP1 transcription factor Dp-1 -0.00436008
KIFAP3 kinesin-associated protein 3 -0.00435681
DHCR7 7-dehydrocholesterol reductase -0.00434873
ABI2 abl-interactor 2 -0.00434537
NECAB3 N-terminal EF-hand calcium binding protein 3 -0.00433825
SLAMF7 SLAM family member 7 -0.00433397
OCRL oculocerebrorenal syndrome of Lowe -0.00433018
GYPC glycophorin C (Gerbich blood group) -0.00432949
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.00432152
MNDA myeloid cell nuclear differentiation antigen -0.00431689
TWSG1 twisted gastrulation BMP signaling modulator 1 -0.00430868
DIAPH2 diaphanous-related formin 2 -0.00430405
MAVS mitochondrial antiviral signaling protein -0.0043003
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00429275
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00428514
NIBAN1 niban apoptosis regulator 1 -0.00428267
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.00428039
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.00427314
RBM5 RNA binding motif protein 5 -0.00427126
POFUT1 protein O-fucosyltransferase 1 -0.00426574