TNFRSF1B Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description tumor necrosis factor receptor superfamily, member 1B|The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7133)
External Link http://www.ncbi.nlm.nih.gov/gene/7133
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Genes

119 interacting proteins for hub protein TNFRSF1B from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ACTG1 actin gamma 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ASB3 ankyrin repeat and SOCS box containing 3
ATAD3A ATPase family, AAA domain containing 3A
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
BAG2 BCL2-associated athanogene 2
BIRC2 baculoviral IAP repeat containing 2
BMX BMX non-receptor tyrosine kinase
C1QBP complement component 1, q subcomponent binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAV1 caveolin 1, caveolae protein, 22kDa
CBWD2 COBW domain containing 2
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK1 cyclin-dependent kinase 1
CLTC clathrin, heavy chain (Hc)
COPB1 coatomer protein complex, subunit beta 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSNK1A1 casein kinase 1, alpha 1
DAXX death-domain associated protein
DBT dihydrolipoamide branched chain transacylase E2
DDB1 damage-specific DNA binding protein 1, 127kDa
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EMC2 ER membrane protein complex subunit 2
EPPK1 epiplakin 1
FANCD2 Fanconi anemia, complementation group D2
FANCI Fanconi anemia, complementation group I
FLNA filamin A, alpha
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HAX1 HCLS1 associated protein X-1
HEATR6 HEAT repeat containing 6
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
IPO7 importin 7
IPO8 importin 8
IRS4 insulin receptor substrate 4
KCTD12 potassium channel tetramerization domain containing 12
KPNB1 karyopherin (importin) beta 1
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LTA lymphotoxin alpha
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAPK8 mitogen-activated protein kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MON2 MON2 homolog (S. cerevisiae)
MYH10 myosin, heavy chain 10, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYLK2 myosin light chain kinase 2
MYO6 myosin VI
PFKP phosphofructokinase, platelet
PHGDH phosphoglycerate dehydrogenase
PKN1 protein kinase N1
POTEKP POTE ankyrin domain family, member K, pseudogene
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RPL23 ribosomal protein L23
RPL38 ribosomal protein L38
RPS14 ribosomal protein S14
RPS16 ribosomal protein S16
RPS18 ribosomal protein S18
RPS27 ribosomal protein S27
RPS27A ribosomal protein S27a
RPS27L ribosomal protein S27-like
RPS3 ribosomal protein S3
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SSR4 signal sequence receptor, delta
STAT1 signal transducer and activator of transcription 1, 91kDa
TANK TRAF family member-associated NFKB activator
TCP1 t-complex 1
TDP2 tyrosyl-DNA phosphodiesterase 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF5 TNF receptor-associated factor 5
TRAIP TRAF interacting protein
TRIM37 tripartite motif containing 37
TRIP13 thyroid hormone receptor interactor 13
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBB tubulin, beta class I
TUBB2B tubulin, beta 2B class IIb
TUBB4A tubulin, beta 4A class IVa
TUFM Tu translation elongation factor, mitochondrial
UBB ubiquitin B
UBC ubiquitin C
VIM vimentin
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XPO1 exportin 1
XPO5 exportin 5
XPOT exportin, tRNA