TNFRSF1B Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description tumor necrosis factor receptor superfamily, member 1B|The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7133)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TNFRSF1B
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Genes

65 co-expressed genes for TNFRSF1B from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADGRE1 adhesion G protein-coupled receptor E1
AIF1 allograft inflammatory factor 1
AOAH acyloxyacyl hydrolase (neutrophil)
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ARRB2 arrestin, beta 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCR1 chemokine (C-C motif) receptor 1
CD1D CD1d molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CFP complement factor properdin
CLEC4A C-type lectin domain family 4, member A
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
CNPY3 canopy FGF signaling regulator 3
COTL1 coactosin-like F-actin binding protein 1
CPVL carboxypeptidase, vitellogenic-like
CTSS cathepsin S
CYBB cytochrome b-245, beta polypeptide
DOK2 docking protein 2, 56kDa
DPEP2 dipeptidase 2
DUSP1 dual specificity phosphatase 1
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGL2 fibrinogen-like 2
FGR FGR proto-oncogene, Src family tyrosine kinase
GMIP GEM interacting protein
HCK HCK proto-oncogene, Src family tyrosine kinase
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGSF6 immunoglobulin superfamily, member 6
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LST1 leukocyte specific transcript 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYD88 myeloid differentiation primary response 88
NAGK N-acetylglucosamine kinase
NCF2 neutrophil cytosolic factor 2
NOD2 nucleotide-binding oligomerization domain containing 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PILRA paired immunoglobin-like type 2 receptor alpha
PPT1 palmitoyl-protein thioesterase 1
PSAP prosaposin
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PYCARD PYD and CARD domain containing
RGS2 regulator of G-protein signaling 2
RHOG ras homolog family member G
RIN3 Ras and Rab interactor 3
RNF130 ring finger protein 130
S100A4 S100 calcium binding protein A4
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
STXBP2 syntaxin binding protein 2
TBXAS1 thromboxane A synthase 1 (platelet)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
THEMIS2 thymocyte selection associated family member 2
TLR2 toll-like receptor 2
TMEM127 transmembrane protein 127
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TYMP thymidine phosphorylase
TYROBP TYRO protein tyrosine kinase binding protein