| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | tumor necrosis factor (ligand) superfamily, member 9|The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 8744) |
| External Link | https://ncbi.nlm.nih.gov/gene/8744 |
| Similar Terms | |
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499 genes differentially expressed following the TNFSF9 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PUF60 | poly-U binding splicing factor 60KDa | 0.0188184 |
| CLIC5 | chloride intracellular channel 5 | 0.0150122 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.0145208 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0132475 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.0132234 |
| CLDN10 | claudin 10 | 0.0126908 |
| ANOS1 | anosmin 1 | 0.0125956 |
| SNX11 | sorting nexin 11 | 0.0123809 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.0122722 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.0118948 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.0118334 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0118308 |
| TMSB15A | thymosin beta 15a | 0.0113879 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0111584 |
| DEFB1 | defensin, beta 1 | 0.0110928 |
| CA2 | carbonic anhydrase II | 0.01108 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0110412 |
| ATF3 | activating transcription factor 3 | 0.0109532 |
| PITX3 | paired-like homeodomain 3 | 0.0108584 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0108343 |
| LY86 | lymphocyte antigen 86 | 0.0107616 |
| TMEM100 | transmembrane protein 100 | 0.0106445 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0106291 |
| FAM107A | family with sequence similarity 107, member A | 0.0105642 |
| GPM6B | glycoprotein M6B | 0.0104391 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0102873 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0102406 |
| OLFML3 | olfactomedin-like 3 | 0.0101858 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0101258 |
| HOXB2 | homeobox B2 | 0.0100762 |
| DOK5 | docking protein 5 | 0.0100645 |
| BTG3 | BTG family, member 3 | 0.0100561 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.0100375 |
| ASRGL1 | asparaginase like 1 | 0.00999038 |
| CHEK2 | checkpoint kinase 2 | 0.00997857 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00997489 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00994948 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00993192 |
| MSLN | mesothelin | 0.00991089 |
| OXTR | oxytocin receptor | 0.0098613 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.009852 |
| CD93 | CD93 molecule | 0.00984048 |
| EGR3 | early growth response 3 | 0.00975082 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00968671 |
| PIP | prolactin-induced protein | 0.00966517 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00960983 |
| THBD | thrombomodulin | 0.00956456 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00954859 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00954359 |
| NRN1 | neuritin 1 | 0.0094602 |
| PLP1 | proteolipid protein 1 | 0.00945486 |
| IER5 | immediate early response 5 | 0.00939978 |
| TAC1 | tachykinin, precursor 1 | 0.0093464 |
| KLK6 | kallikrein-related peptidase 6 | 0.00922344 |
| TYRP1 | tyrosinase-related protein 1 | 0.00919925 |
| KLK10 | kallikrein-related peptidase 10 | 0.00915808 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00914933 |
| HOXB7 | homeobox B7 | 0.00910863 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00908065 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00907258 |
| OLFML2A | olfactomedin-like 2A | 0.00903988 |
| HAL | histidine ammonia-lyase | 0.0090274 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 | 0.00891577 |
| HBB | hemoglobin, beta | 0.00888511 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00886238 |
| MUC16 | mucin 16, cell surface associated | 0.00885042 |
| KLK7 | kallikrein-related peptidase 7 | 0.00880943 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00880576 |
| KLK8 | kallikrein-related peptidase 8 | 0.00879401 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00874928 |
| RET | ret proto-oncogene | 0.00874226 |
| CPM | carboxypeptidase M | 0.00871978 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00863208 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00857819 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00856763 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00855437 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00855189 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00854965 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00854312 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00849494 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00847461 |
| APOC1 | apolipoprotein C-I | 0.00843635 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00842973 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0084243 |
| PLIN2 | perilipin 2 | 0.0083909 |
| RGS1 | regulator of G-protein signaling 1 | 0.00835496 |
| IFI44L | interferon-induced protein 44-like | 0.00832047 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00829232 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00829079 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00828213 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.0082731 |
| MYO1C | myosin IC | 0.00824482 |
| FOLR1 | folate receptor 1 (adult) | 0.0082345 |
| PODXL | podocalyxin-like | 0.00818074 |
| C5ORF30 | chromosome 5 open reading frame 30 | 0.00815341 |
| MT1M | metallothionein 1M | 0.00810109 |
| GPX7 | glutathione peroxidase 7 | 0.00809781 |
| IQCG | IQ motif containing G | 0.00808513 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0080763 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00807147 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00805982 |
| CLDN5 | claudin 5 | 0.0080351 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0079729 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00797269 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00793484 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00792538 |
| NNMT | nicotinamide N-methyltransferase | 0.00792487 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00792172 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00785066 |
| LRRC6 | leucine rich repeat containing 6 | 0.00785016 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.0078231 |
| RGCC | regulator of cell cycle | 0.00780448 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00775487 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00774123 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.0077373 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00773503 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00770484 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00768943 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00766021 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00764951 |
| GAS1 | growth arrest-specific 1 | 0.00763279 |
| MYOF | myoferlin | 0.00762699 |
| EMX2 | empty spiracles homeobox 2 | 0.00759755 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00757429 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00756603 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00755706 |
| MT1F | metallothionein 1F | 0.00752331 |
| QKI | QKI, KH domain containing, RNA binding | 0.00750876 |
| RBM34 | RNA binding motif protein 34 | 0.00747296 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00746339 |
| PALMD | palmdelphin | 0.00745737 |
| PTDSS1 | phosphatidylserine synthase 1 | 0.00743308 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00735999 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00735758 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.00735605 |
| GPC4 | glypican 4 | 0.00735141 |
| PMP2 | peripheral myelin protein 2 | 0.00735094 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00733393 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00732835 |
| MGLL | monoglyceride lipase | 0.00727142 |
| IL15 | interleukin 15 | 0.00726463 |
| NCALD | neurocalcin delta | 0.00725549 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0072487 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 0.00724608 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00724318 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00721605 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00720742 |
| LAPTM5 | lysosomal protein transmembrane 5 | 0.00718834 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00718469 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00717749 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00712038 |
| AQP4 | aquaporin 4 | 0.00711119 |
| TSPAN3 | tetraspanin 3 | 0.00710771 |
| MMD | monocyte to macrophage differentiation-associated | 0.00709073 |
| NTS | neurotensin | 0.00708781 |
| ACKR3 | atypical chemokine receptor 3 | 0.00708007 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00707082 |
| ADIRF | adipogenesis regulatory factor | 0.00705451 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00701545 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00700766 |
| KRT23 | keratin 23, type I | 0.00699962 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00699182 |
| PLSCR4 | phospholipid scramblase 4 | 0.00698939 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00696354 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 0.00696112 |
| NME5 | NME/NM23 family member 5 | 0.00694693 |
| ANXA1 | annexin A1 | 0.00692078 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.0069103 |
| PLSCR1 | phospholipid scramblase 1 | 0.00690564 |
| MX1 | MX dynamin-like GTPase 1 | 0.00690363 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00688577 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00688418 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00687401 |
| DAXX | death-domain associated protein | 0.00687045 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00687009 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0068643 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00685871 |
| TRIM22 | tripartite motif containing 22 | 0.0068376 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00678814 |
| IFI44 | interferon-induced protein 44 | 0.00677941 |
| LYPLA1 | lysophospholipase I | 0.00677098 |
| TMEM47 | transmembrane protein 47 | 0.00676312 |
| SELENOW | selenoprotein W | 0.00676056 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00671574 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0067052 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00669769 |
| PLAT | plasminogen activator, tissue | 0.0066368 |
| C8ORF33 | chromosome 8 open reading frame 33 | 0.0066362 |
| JAM2 | junctional adhesion molecule 2 | 0.00661343 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 | 0.00661144 |
| SP110 | SP110 nuclear body protein | 0.00660772 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.00660712 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.0065902 |
| MT1E | metallothionein 1E | 0.00655639 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00652551 |
| NAV3 | neuron navigator 3 | 0.00649713 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00648791 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00648346 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00647995 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0064745 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00647144 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00646203 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | 0.0064222 |
| HEATR1 | HEAT repeat containing 1 | 0.00640949 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00637965 |
| AHR | aryl hydrocarbon receptor | 0.0063692 |
| S1PR1 | sphingosine-1-phosphate receptor 1 | 0.00635706 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0063444 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00634373 |
| CCL15 | chemokine (C-C motif) ligand 15 | 0.00634111 |
| PLK2 | polo-like kinase 2 | 0.00633526 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00632758 |
| AZIN1 | antizyme inhibitor 1 | 0.00632544 |
| PLEK | pleckstrin | 0.00632382 |
| IL1R1 | interleukin 1 receptor, type I | 0.00631492 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00628831 |
| RPS27L | ribosomal protein S27-like | 0.00628588 |
| QDPR | quinoid dihydropteridine reductase | 0.00628375 |
| MYRF | myelin regulatory factor | 0.00628069 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00627857 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00627104 |
| IL33 | interleukin 33 | 0.00626897 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00624991 |
| STOM | stomatin | 0.00622288 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00618938 |
| ASPA | aspartoacylase | 0.00618754 |
| KRT10 | keratin 10, type I | 0.00618037 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00616562 |
| MX2 | MX dynamin-like GTPase 2 | 0.00616101 |
| MEN1 | multiple endocrine neoplasia I | 0.00614625 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00613509 |
| CCDC6 | coiled-coil domain containing 6 | 0.00613026 |
| MSR1 | macrophage scavenger receptor 1 | 0.00612709 |
| CD83 | CD83 molecule | 0.00612461 |
| RND3 | Rho family GTPase 3 | 0.00612047 |
| PCDH17 | protocadherin 17 | 0.00611772 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.00611377 |
| NRCAM | neuronal cell adhesion molecule | 0.00609706 |
| FGF9 | fibroblast growth factor 9 | 0.00609606 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00608713 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00607466 |
| PIR | pirin (iron-binding nuclear protein) | 0.00606937 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.00606098 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00604165 |
| PLLP | plasmolipin | 0.00603425 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00603227 |
| CALCA | calcitonin-related polypeptide alpha | 0.00603158 |
| NPR1 | natriuretic peptide receptor 1 | 0.00601274 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.00601034 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00600811 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP9 | matrix metallopeptidase 9 | -0.0182761 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0181109 |
| OLFM4 | olfactomedin 4 | -0.0150048 |
| POU2AF1 | POU class 2 associating factor 1 | -0.0149555 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0144002 |
| SIRT3 | sirtuin 3 | -0.0143958 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0141597 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0135836 |
| MMP12 | matrix metallopeptidase 12 | -0.0132909 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0129324 |
| CD9 | CD9 molecule | -0.0128376 |
| DSP | desmoplakin | -0.0122407 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.0121853 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.0121841 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0118184 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.0112605 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0109322 |
| LYZ | lysozyme | -0.0106652 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0105589 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0105392 |
| GSTT1 | glutathione S-transferase theta 1 | -0.0104656 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.0103939 |
| NELL2 | NEL-like 2 (chicken) | -0.0103486 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.010272 |
| CHKB | choline kinase beta | -0.0102006 |
| KRT18 | keratin 18, type I | -0.0100689 |
| REG1A | regenerating islet-derived 1 alpha | -0.0100558 |
| PITX1 | paired-like homeodomain 1 | -0.00999574 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00995303 |
| CD8A | CD8a molecule | -0.00989256 |
| PERP | PERP, TP53 apoptosis effector | -0.00975156 |
| XIC | X chromosome inactivation center | -0.00952225 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00946551 |
| FGL2 | fibrinogen-like 2 | -0.00944837 |
| HIRA | histone cell cycle regulator | -0.00944002 |
| CTSZ | cathepsin Z | -0.00943306 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00936855 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00933415 |
| KRT16 | keratin 16, type I | -0.00925778 |
| BSG | basigin (Ok blood group) | -0.00915083 |
| STK39 | serine threonine kinase 39 | -0.00904517 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00893104 |
| MMP3 | matrix metallopeptidase 3 | -0.00892842 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00886265 |
| NDRG1 | N-myc downstream regulated 1 | -0.00884495 |
| KRT15 | keratin 15, type I | -0.00880192 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00875165 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00868073 |
| MAP7 | microtubule-associated protein 7 | -0.00858441 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00845396 |
| PRDX2 | peroxiredoxin 2 | -0.00845273 |
| LCN2 | lipocalin 2 | -0.00841689 |
| DUOX2 | dual oxidase 2 | -0.00837966 |
| CD2 | CD2 molecule | -0.00829743 |
| REG1B | regenerating islet-derived 1 beta | -0.00829398 |
| IL32 | interleukin 32 | -0.00818526 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00811517 |
| BLNK | B-cell linker | -0.00808729 |
| CLCA1 | chloride channel accessory 1 | -0.00808296 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00802042 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0079849 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00791323 |
| IL7R | interleukin 7 receptor | -0.00789387 |
| MTA1 | metastasis associated 1 | -0.00777371 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00775787 |
| RXRA | retinoid X receptor, alpha | -0.00774904 |
| ALB | albumin | -0.00774489 |
| TBX3 | T-box 3 | -0.00769988 |
| COQ8A | coenzyme Q8A | -0.00768548 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00766031 |
| PAGE4 | P antigen family, member 4 (prostate associated) | -0.00765786 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00760813 |
| SVIL | supervillin | -0.0075563 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00747052 |
| PAX5 | paired box 5 | -0.00746966 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00745696 |
| CST7 | cystatin F (leukocystatin) | -0.00745093 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.00738554 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0073523 |
| DES | desmin | -0.00734246 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00729305 |
| PCP4 | Purkinje cell protein 4 | -0.00728803 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00723103 |
| HK2 | hexokinase 2 | -0.00718365 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00713373 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00711799 |
| ORM1 | orosomucoid 1 | -0.00710647 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00708225 |
| PLBD1 | phospholipase B domain containing 1 | -0.00707409 |
| GSE1 | Gse1 coiled-coil protein | -0.00707304 |
| CLIC3 | chloride intracellular channel 3 | -0.00702292 |
| NKG7 | natural killer cell granule protein 7 | -0.00700828 |
| APOA2 | apolipoprotein A-II | -0.00698194 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00696302 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00695699 |
| PRF1 | perforin 1 (pore forming protein) | -0.00695568 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00693833 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0069316 |
| FST | follistatin | -0.00690312 |
| REG3A | regenerating islet-derived 3 alpha | -0.00687683 |
| CD19 | CD19 molecule | -0.00686338 |
| KRT13 | keratin 13, type I | -0.00678331 |
| PRKCZ | protein kinase C, zeta | -0.00673003 |
| DICER1 | dicer 1, ribonuclease type III | -0.00671317 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.0067008 |
| PKM | pyruvate kinase, muscle | -0.00668255 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00667088 |
| CDC34 | cell division cycle 34 | -0.00666829 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00665884 |
| APOB | apolipoprotein B | -0.00665348 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00665161 |
| LMOD1 | leiomodin 1 (smooth muscle) | -0.00664953 |
| ABHD2 | abhydrolase domain containing 2 | -0.00664215 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00663443 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00663227 |
| PKP1 | plakophilin 1 | -0.00661189 |
| CES1 | carboxylesterase 1 | -0.0065931 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00658265 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00655872 |
| CD27 | CD27 molecule | -0.00654571 |
| SDC2 | syndecan 2 | -0.00654496 |
| SMAD7 | SMAD family member 7 | -0.00653111 |
| DENND1B | DENN/MADD domain containing 1B | -0.00652096 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00651583 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00649286 |
| GNLY | granulysin | -0.00648743 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | -0.0064856 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00647661 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00646795 |
| MXRA7 | matrix-remodelling associated 7 | -0.0064669 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00645688 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00643768 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00643287 |
| CLDN4 | claudin 4 | -0.00642852 |
| FABP1 | fatty acid binding protein 1, liver | -0.00642007 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.0064108 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00640896 |
| NAGK | N-acetylglucosamine kinase | -0.00640722 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00640667 |
| EPHB2 | EPH receptor B2 | -0.00640001 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00639494 |
| GLS | glutaminase | -0.00639334 |
| APOA1 | apolipoprotein A-I | -0.00635869 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00635512 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | -0.00635021 |
| USP20 | ubiquitin specific peptidase 20 | -0.00634477 |
| MLXIP | MLX interacting protein | -0.00633424 |
| SERINC5 | serine incorporator 5 | -0.00631336 |
| CTSK | cathepsin K | -0.00626993 |
| CST3 | cystatin C | -0.00626141 |
| JUP | junction plakoglobin | -0.00626134 |
| DSE | dermatan sulfate epimerase | -0.00625322 |
| CALD1 | caldesmon 1 | -0.00623852 |
| FBLN1 | fibulin 1 | -0.0062061 |
| FLNA | filamin A, alpha | -0.00618368 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00618274 |
| LPIN1 | lipin 1 | -0.00617401 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00616788 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0061403 |
| TRIB2 | tribbles pseudokinase 2 | -0.00613552 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00612062 |
| KRT19 | keratin 19, type I | -0.00611778 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00610013 |
| MMP1 | matrix metallopeptidase 1 | -0.00609115 |
| PFKL | phosphofructokinase, liver | -0.00608763 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00608354 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00608286 |
| HIC2 | hypermethylated in cancer 2 | -0.00607774 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00607131 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | -0.00605334 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00603114 |
| ARG2 | arginase 2 | -0.00602956 |
| FOXF2 | forkhead box F2 | -0.00602904 |
| CBX6 | chromobox homolog 6 | -0.0060203 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00600267 |
| PRSS8 | protease, serine, 8 | -0.00600023 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00599603 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.00599303 |
| COMP | cartilage oligomeric matrix protein | -0.00597492 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 | -0.00593676 |
| TCAF1 | TRPM8 channel-associated factor 1 | -0.00593514 |
| ELN | elastin | -0.00593445 |
| SYNGR3 | synaptogyrin 3 | -0.00592444 |
| COL2A1 | collagen, type II, alpha 1 | -0.00590734 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00589897 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00588822 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00587484 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00586677 |
| EPS8L2 | EPS8-like 2 | -0.0058652 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00585626 |
| WSB2 | WD repeat and SOCS box containing 2 | -0.00584995 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00584021 |
| PALLD | palladin, cytoskeletal associated protein | -0.00583757 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00582156 |
| SNX10 | sorting nexin 10 | -0.00582048 |
| DGS2 | DiGeorge syndrome/velocardiofacial syndrome complex 2 | -0.00580723 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00577693 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00577237 |
| HBZ | hemoglobin, zeta | -0.00577117 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 | -0.00576597 |
| VIL1 | villin 1 | -0.00575058 |
| PMM2 | phosphomannomutase 2 | -0.00574093 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene | -0.00572696 |
| DBF4 | DBF4 zinc finger | -0.00572502 |
| FN1 | fibronectin 1 | -0.00572008 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | -0.00570866 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00564749 |
| NPTN | neuroplastin | -0.00563111 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.00560062 |
| ITK | IL2-inducible T-cell kinase | -0.00559437 |
| TSPAN4 | tetraspanin 4 | -0.00559022 |
| CTSB | cathepsin B | -0.00557192 |
| NMU | neuromedin U | -0.00557084 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.0055656 |
| SDC1 | syndecan 1 | -0.00554978 |
| TTR | transthyretin | -0.00553806 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00553801 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00553304 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00553103 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00551593 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.0055087 |
| TSC2 | tuberous sclerosis 2 | -0.00550807 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00549017 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00548321 |
| EXOSC4 | exosome component 4 | -0.00547926 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00546916 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00546718 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00546334 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00545287 |
| NVL | nuclear VCP-like | -0.0054508 |
| ESRP2 | epithelial splicing regulatory protein 2 | -0.00544451 |
| DTX2 | deltex 2, E3 ubiquitin ligase | -0.00543949 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00543867 |
| S100A7 | S100 calcium binding protein A7 | -0.00542471 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00542189 |
| NFE2 | nuclear factor, erythroid 2 | -0.00541853 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -0.00541295 |
| INTS1 | integrator complex subunit 1 | -0.00539211 |
| SBF1 | SET binding factor 1 | -0.00538861 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00536735 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | -0.00535867 |
| CKM | creatine kinase, muscle | -0.00535769 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00535717 |
| AHSG | alpha-2-HS-glycoprotein | -0.00534887 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.00534879 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | -0.00534603 |
| KRT14 | keratin 14, type I | -0.00534412 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | -0.00534169 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | -0.00533834 |
