TORC1 complex Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p. (Gene Ontology, GO_0031931)
External Link http://amigo.geneontology.org/amigo/term/GO:0031931
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Genes

6 proteins localized to the TORC1 complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
AKT1S1 AKT1 substrate 1 (proline-rich)
LARP1 La ribonucleoprotein domain family, member 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
RPTOR regulatory associated protein of MTOR, complex 1
TTI1 TELO2 interacting protein 1