TORC2 complex Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p. (Gene Ontology, GO_0031932)
External Link http://amigo.geneontology.org/amigo/term/GO:0031932
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Genes

8 proteins localized to the TORC2 complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
MAPKAP1 mitogen-activated protein kinase associated protein 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
PRR5 proline rich 5 (renal)
PRR5L proline rich 5 like
RICTOR RPTOR independent companion of MTOR, complex 2
SESN2 sestrin 2
TTI1 TELO2 interacting protein 1