TP53 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description tumor protein p53|This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013] (NCBI Entrez Gene Database, 7157)
External Link http://www.ncbi.nlm.nih.gov/gene/7157
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Genes

478 interacting proteins for hub protein TP53 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTA1 actin, alpha 1, skeletal muscle
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AGBL2 ATP/GTP binding protein-like 2
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALK anaplastic lymphoma receptor tyrosine kinase
ANK2 ankyrin 2, neuronal
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANXA3 annexin A3
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOH apolipoprotein H (beta-2-glycoprotein I)
APTX aprataxin
AR androgen receptor
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL3 ADP-ribosylation factor-like 3
ASF1A anti-silencing function 1A histone chaperone
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF3 activating transcription factor 3
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAG1 BCL2-associated athanogene
BAK1 BCL2-antagonist/killer 1
BANP BTG3 associated nuclear protein
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCR breakpoint cluster region
BHLHE40 basic helix-loop-helix family, member e40
BLM Bloom syndrome, RecQ helicase-like
BMP1 bone morphogenetic protein 1
BMX BMX non-receptor tyrosine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRD8 bromodomain containing 8
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTBD2 BTB (POZ) domain containing 2
BTG2 BTG family, member 2
BTK Bruton agammaglobulinemia tyrosine kinase
CA11 carbonic anhydrase XI
CABLES1 Cdk5 and Abl enzyme substrate 1
CABLES2 Cdk5 and Abl enzyme substrate 2
CAPN1 calpain 1, (mu/I) large subunit
CARM1 coactivator-associated arginine methyltransferase 1
CCAR1 cell division cycle and apoptosis regulator 1
CCDC106 coiled-coil domain containing 106
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCNA2 cyclin A2
CCNG1 cyclin G1
CCNH cyclin H
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CD40LG CD40 ligand
CDC14A cell division cycle 14A
CDC14B cell division cycle 14B
CDC25C cell division cycle 25C
CDC42 cell division cycle 42
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK7 cyclin-dependent kinase 7
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CFLAR CASP8 and FADD-like apoptosis regulator
CHD3 chromodomain helicase DNA binding protein 3
CHD8 chromodomain helicase DNA binding protein 8
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
COPS2 COP9 signalosome subunit 2
COPS3 COP9 signalosome subunit 3
COPS4 COP9 signalosome subunit 4
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COPS7A COP9 signalosome subunit 7A
COPS8 COP9 signalosome subunit 8
COX17 COX17 cytochrome c oxidase copper chaperone
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CSNK1G1 casein kinase 1, gamma 1
CSNK1G2 casein kinase 1, gamma 2
CSNK1G3 casein kinase 1, gamma 3
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTBP1 C-terminal binding protein 1
CUL7 cullin 7
CUL9 cullin 9
DAB2IP DAB2 interacting protein
DAPK1 death-associated protein kinase 1
DAPK3 death-associated protein kinase 3
DAXX death-domain associated protein
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DHCR24 24-dehydrocholesterol reductase
DHFR dihydrofolate reductase
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPH1 diphthamide biosynthesis 1
DUSP26 dual specificity phosphatase 26 (putative)
DVL2 dishevelled segment polarity protein 2
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
E2F1 E2F transcription factor 1
E4F1 E4F transcription factor 1
EEF2 eukaryotic translation elongation factor 2
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGR1 early growth response 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ELL elongation factor RNA polymerase II
ELN elastin
EP300 E1A binding protein p300
EPHA3 EPH receptor A3
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC6 excision repair cross-complementation group 6
ERH enhancer of rudimentary homolog (Drosophila)
ESR1 estrogen receptor 1
ETHE1 ethylmalonic encephalopathy 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM173A family with sequence similarity 173, member A
FBXO11 F-box protein 11
FKBP3 FK506 binding protein 3, 25kDa
FXYD6 FXYD domain containing ion transport regulator 6
GADD45A growth arrest and DNA-damage-inducible, alpha
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GPS1 G protein pathway suppressor 1
GPS2 G protein pathway suppressor 2
GRK5 G protein-coupled receptor kinase 5
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSTM4 glutathione S-transferase mu 4
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTPBP4 GTP binding protein 4
GUSBP1 glucuronidase, beta pseudogene 1
H2AFX H2A histone family, member X
HABP4 hyaluronan binding protein 4
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
HIPK3 homeodomain interacting protein kinase 3
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HTT huntingtin
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFI16 interferon, gamma-inducible protein 16
IFRD1 interferon-related developmental regulator 1
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ING1 inhibitor of growth family, member 1
ING2 inhibitor of growth family, member 2
ING4 inhibitor of growth family, member 4
ING5 inhibitor of growth family, member 5
IRF9 interferon regulatory factor 9
ITCH itchy E3 ubiquitin protein ligase
JMY junction mediating and regulatory protein, p53 cofactor
KANSL1 KAT8 regulatory NSL complex subunit 1
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
KAT5 K(lysine) acetyltransferase 5
KAT6A K(lysine) acetyltransferase 6A
KAT7 K(lysine) acetyltransferase 7
KAT8 K(lysine) acetyltransferase 8
KDM1A lysine (K)-specific demethylase 1A
KIAA0087 KIAA0087
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KMT2A lysine (K)-specific methyltransferase 2A
KMT2E lysine (K)-specific methyltransferase 2E
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNB1 karyopherin (importin) beta 1
LAMA4 laminin, alpha 4
LINC01194 long intergenic non-protein coding RNA 1194
LOC613037 nuclear pore complex interacting protein pseudogene
LRPPRC leucine-rich pentatricopeptide repeat containing
MAD2L1BP MAD2L1 binding protein
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAGEA2 melanoma antigen family A2
MAGEB18 melanoma antigen family B18
MAP1B microtubule-associated protein 1B
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MED1 mediator complex subunit 1
MED17 mediator complex subunit 17
MEN1 multiple endocrine neoplasia I
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MNAT1 MNAT CDK-activating kinase assembly factor 1
MNDA myeloid cell nuclear differentiation antigen
MPHOSPH6 M-phase phosphoprotein 6
MSH2 mutS homolog 2
MSX1 msh homeobox 1
MT1A metallothionein 1A
MTA1 metastasis associated 1
MTA2 metastasis associated 1 family, member 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYL9 myosin, light chain 9, regulatory
NAP1L1 nucleosome assembly protein 1-like 1
NCL nucleolin
NCOA2 nuclear receptor coactivator 2
NCOR1 nuclear receptor corepressor 1
NDN necdin, melanoma antigen (MAGE) family member
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFYA nuclear transcription factor Y, alpha
NFYB nuclear transcription factor Y, beta
NMT1 N-myristoyltransferase 1
NMT2 N-myristoyltransferase 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUMB numb homolog (Drosophila)
OTUD5 OTU deubiquitinase 5
PADI4 peptidyl arginine deiminase, type IV
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAGR1 PAXIP1 associated glutamate-rich protein 1
PARP1 poly (ADP-ribose) polymerase 1
PBK PDZ binding kinase
PCDHA4 protocadherin alpha 4
PHB prohibitin
PHF1 PHD finger protein 1
PIAS1 protein inhibitor of activated STAT, 1
PIAS2 protein inhibitor of activated STAT, 2
PIAS4 protein inhibitor of activated STAT, 4
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIWIL1 piwi-like RNA-mediated gene silencing 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PNP purine nucleoside phosphorylase
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PPA1 pyrophosphatase (inorganic) 1
PPID peptidylprolyl isomerase D
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP4C protein phosphatase 4, catalytic subunit
PRAM1 PML-RARA regulated adaptor molecule 1
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PRMT1 protein arginine methyltransferase 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTTG1 pituitary tumor-transforming 1
RAB4A RAB4A, member RAS oncogene family
RAD23A RAD23 homolog A (S. cerevisiae)
RAD51 RAD51 recombinase
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RB1 retinoblastoma 1
RB1CC1 RB1-inducible coiled-coil 1
RBBP5 retinoblastoma binding protein 5
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RFC1 replication factor C (activator 1) 1, 145kDa
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNF38 ring finger protein 38
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPA1 replication protein A1, 70kDa
RPL11 ribosomal protein L11
RPL23 ribosomal protein L23
RPL5 ribosomal protein L5
RPS27A ribosomal protein S27a
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS7 ribosomal protein S7
RRM2 ribonucleotide reductase M2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RYBP RING1 and YY1 binding protein
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
S100B S100 calcium binding protein B
SAE1 SUMO1 activating enzyme subunit 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAMP1 secretory carrier membrane protein 1
SERBP1 SERPINE1 mRNA binding protein 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD2 SET domain containing 2
SETD7 SET domain containing (lysine methyltransferase) 7
SFN stratifin
SHISA5 shisa family member 5
SIN3A SIN3 transcription regulator family member A
SIN3B SIN3 transcription regulator family member B
SIRT1 sirtuin 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMN1 survival of motor neuron 1, telomeric
SMYD2 SET and MYND domain containing 2
SNRPN small nuclear ribonucleoprotein polypeptide N
SNURF SNRPN upstream reading frame
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSTR3 somatostatin receptor 3
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
STK17A serine/threonine kinase 17a
STK4 serine/threonine kinase 4
STRA13 stimulated by retinoic acid 13
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX5 syntaxin 5
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SUMO1 small ubiquitin-like modifier 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TADA1 transcriptional adaptor 1
TADA2A transcriptional adaptor 2A
TADA3 transcriptional adaptor 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBP TATA box binding protein
TDG thymine-DNA glycosylase
TEC tec protein tyrosine kinase
TEP1 telomerase-associated protein 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFDP1 transcription factor Dp-1
THAP8 THAP domain containing 8
THRB thyroid hormone receptor, beta
TIMP3 TIMP metallopeptidase inhibitor 3
TK1 thymidine kinase 1, soluble
TMSB4X thymosin beta 4, X-linked
TOE1 target of EGR1, member 1 (nuclear)
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP53BP2 tumor protein p53 binding protein 2
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP53RK TP53 regulating kinase
TP53TG1 TP53 target 1 (non-protein coding)
TP63 tumor protein p63
TP73 tumor protein p73
TRAPPC11 trafficking protein particle complex 11
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRIM3 tripartite motif containing 3
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRRAP transformation/transcription domain-associated protein
TSG101 tumor susceptibility 101
TTK TTK protein kinase
TTLL5 tubulin tyrosine ligase-like family member 5
TXN thioredoxin
UBB ubiquitin B
UBC ubiquitin C
UBE2A ubiquitin-conjugating enzyme E2A
UBE2I ubiquitin-conjugating enzyme E2I
UBE2K ubiquitin-conjugating enzyme E2K
UBE2N ubiquitin-conjugating enzyme E2N
UBE3A ubiquitin protein ligase E3A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP11 ubiquitin specific peptidase 11
USP39 ubiquitin specific peptidase 39
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VRK1 vaccinia related kinase 1
VRK2 vaccinia related kinase 2
WDR33 WD repeat domain 33
WDR48 WD repeat domain 48
WDR5 WD repeat domain 5
WRN Werner syndrome, RecQ helicase-like
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XPO1 exportin 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRN1 5'-3' exoribonuclease 1
YBX1 Y box binding protein 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor
ZBTB2 zinc finger and BTB domain containing 2
ZBTB7A zinc finger and BTB domain containing 7A
ZCCHC10 zinc finger, CCHC domain containing 10
ZHX1 zinc fingers and homeoboxes 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZMYND11 zinc finger, MYND-type containing 11
ZNF148 zinc finger protein 148
ZNF24 zinc finger protein 24
ZNF385A zinc finger protein 385A
ZNF420 zinc finger protein 420
ZNF585B zinc finger protein 585B
ZNHIT1 zinc finger, HIT-type containing 1