| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | tumor protein p53|This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013] (NCBI Entrez Gene Database, 7157) |
| External Link | https://ncbi.nlm.nih.gov/gene/7157 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the TP53 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.0175693 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.013619 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0108161 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.0106038 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00959881 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0095393 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00884848 |
| CHEK1 | checkpoint kinase 1 | 0.00872495 |
| MMP8 | matrix metallopeptidase 8 | 0.00868698 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00863891 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00858673 |
| CSTA | cystatin A (stefin A) | 0.00842813 |
| ATG5 | autophagy related 5 | 0.0083893 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00835344 |
| TMSB15A | thymosin beta 15a | 0.00830099 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00823186 |
| S100A8 | S100 calcium binding protein A8 | 0.00821571 |
| TTK | TTK protein kinase | 0.00821296 |
| PLK1 | polo-like kinase 1 | 0.00814347 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00806098 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00804463 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.0079621 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00796204 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 0.00792935 |
| ELANE | elastase, neutrophil expressed | 0.00792868 |
| S100A9 | S100 calcium binding protein A9 | 0.0076966 |
| DCK | deoxycytidine kinase | 0.0076162 |
| CA2 | carbonic anhydrase II | 0.00748726 |
| PODXL | podocalyxin-like | 0.00747751 |
| TPM4 | tropomyosin 4 | 0.0074568 |
| FBXO11 | F-box protein 11 | 0.00743532 |
| CCNA2 | cyclin A2 | 0.00731938 |
| FABP7 | fatty acid binding protein 7, brain | 0.00730425 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.00730245 |
| IPO7 | importin 7 | 0.00728461 |
| AK4 | adenylate kinase 4 | 0.00725883 |
| NKX2-1 | NK2 homeobox 1 | 0.00724702 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00712932 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00706923 |
| DNTT | DNA nucleotidylexotransferase | 0.00704956 |
| MCM10 | minichromosome maintenance complex component 10 | 0.00699165 |
| CHI3L2 | chitinase 3-like 2 | 0.00693958 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00691642 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00686159 |
| TPX2 | TPX2, microtubule-associated | 0.00683697 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00682314 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 0.00681398 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0067826 |
| NRN1 | neuritin 1 | 0.00675356 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00675346 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00671866 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0067022 |
| AQP4 | aquaporin 4 | 0.00668592 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00667225 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.00665843 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00660312 |
| KIF23 | kinesin family member 23 | 0.00659895 |
| BPI | bactericidal/permeability-increasing protein | 0.00659217 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.00658184 |
| C1ORF112 | chromosome 1 open reading frame 112 | 0.00657881 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.00651142 |
| MED6 | mediator complex subunit 6 | 0.00650863 |
| PBK | PDZ binding kinase | 0.00646968 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00643418 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00643097 |
| ANXA3 | annexin A3 | 0.0063958 |
| CDC6 | cell division cycle 6 | 0.00636302 |
| PLP1 | proteolipid protein 1 | 0.00633089 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00632332 |
| RPA3 | replication protein A3, 14kDa | 0.0062473 |
| CRIPT | cysteine-rich PDZ-binding protein | 0.00624337 |
| EPHA4 | EPH receptor A4 | 0.00622012 |
| ERCC4 | excision repair cross-complementation group 4 | 0.00618546 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.00618355 |
| GLUL | glutamate-ammonia ligase | 0.00615753 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00614203 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.00613232 |
| XPO7 | exportin 7 | 0.00612527 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00609228 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.00608697 |
| TEX30 | testis expressed 30 | 0.00607971 |
| ARG1 | arginase 1 | 0.00607743 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00607435 |
| SET | SET nuclear proto-oncogene | 0.00607232 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00606963 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) | 0.00604955 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00604508 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00603872 |
| RPA2 | replication protein A2, 32kDa | 0.00603383 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00603348 |
| CDC25A | cell division cycle 25A | 0.00601575 |
| NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 | 0.0060139 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.00600236 |
| AQP9 | aquaporin 9 | 0.00600158 |
| CCNB2 | cyclin B2 | 0.0059921 |
| BEX1 | brain expressed, X-linked 1 | 0.00599012 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00597401 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | 0.00597035 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00596732 |
| RRM2 | ribonucleotide reductase M2 | 0.00596092 |
| PPID | peptidylprolyl isomerase D | 0.00595224 |
| RAD51AP1 | RAD51 associated protein 1 | 0.00593702 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00590652 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00590376 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00589303 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00589186 |
| HSPA14 | heat shock 70kDa protein 14 | 0.00587167 |
| DOP1B | DOP1 leucine zipper like protein B | 0.0058696 |
| DOK5 | docking protein 5 | 0.00585829 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00585 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.00583863 |
| PSPH | phosphoserine phosphatase | 0.00582142 |
| PRTN3 | proteinase 3 | 0.00581394 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 | 0.00580141 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | 0.00576775 |
| MKI67 | marker of proliferation Ki-67 | 0.00576059 |
| KRT15 | keratin 15, type I | 0.00576006 |
| CEP55 | centrosomal protein 55kDa | 0.00574494 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.0057326 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0057288 |
| OBI1 | ORC ubiquitin ligase 1 | 0.00572642 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00572079 |
| RBM48 | RNA binding motif protein 48 | 0.00571873 |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 | 0.0057124 |
| KIF11 | kinesin family member 11 | 0.00570663 |
| CENPU | centromere protein U | 0.00569627 |
| YEATS4 | YEATS domain containing 4 | 0.00569496 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00569147 |
| PTHLH | parathyroid hormone-like hormone | 0.00569117 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00567241 |
| TAGLN2 | transgelin 2 | 0.00567196 |
| KAT7 | K(lysine) acetyltransferase 7 | 0.00566845 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00566334 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | 0.00565488 |
| ZWILCH | zwilch kinetochore protein | 0.0056341 |
| FAIM | Fas apoptotic inhibitory molecule | 0.00562854 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 0.00561551 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.00559059 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00558513 |
| TIPIN | TIMELESS interacting protein | 0.00558064 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00557961 |
| KIF20A | kinesin family member 20A | 0.00557572 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00556674 |
| MED21 | mediator complex subunit 21 | 0.00556166 |
| CCK | cholecystokinin | 0.00555798 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00554744 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00554689 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00552712 |
| METTL18 | methyltransferase like 18 | 0.00552334 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00549932 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00548113 |
| PRKCH | protein kinase C, eta | 0.0054782 |
| OIP5 | Opa interacting protein 5 | 0.00547547 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00547412 |
| MRPL36 | mitochondrial ribosomal protein L36 | 0.005441 |
| VASH2 | vasohibin 2 | 0.00541655 |
| ZNF22 | zinc finger protein 22 | 0.0053984 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 0.00538952 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00537455 |
| PAQR3 | progestin and adipoQ receptor family member III | 0.00536857 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00535756 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00534492 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 | 0.00534402 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0053405 |
| RAD51 | RAD51 recombinase | 0.00533255 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00531745 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.00530718 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0052894 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00528555 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00527064 |
| HMGB2 | high mobility group box 2 | 0.00526375 |
| ATF4 | activating transcription factor 4 | 0.00526318 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00526202 |
| STMN1 | stathmin 1 | 0.0052374 |
| PPAT | phosphoribosyl pyrophosphate amidotransferase | 0.00523108 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.0052244 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00520274 |
| ZNF473 | zinc finger protein 473 | 0.00519806 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00518471 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0051541 |
| IRX5 | iroquois homeobox 5 | 0.00515166 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | 0.00514321 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.00513212 |
| MPHOSPH6 | M-phase phosphoprotein 6 | 0.00512381 |
| SMC2 | structural maintenance of chromosomes 2 | 0.00512356 |
| YME1L1 | YME1-like 1 ATPase | 0.00510593 |
| CCKBR | cholecystokinin B receptor | 0.00510173 |
| NAP1L2 | nucleosome assembly protein 1-like 2 | 0.00509511 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00509434 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00508177 |
| CLC | Charcot-Leyden crystal galectin | 0.00507902 |
| CDK1 | cyclin-dependent kinase 1 | 0.00507167 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00506911 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00505383 |
| FAM107A | family with sequence similarity 107, member A | 0.00504365 |
| NDC1 | NDC1 transmembrane nucleoporin | 0.00504338 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00504217 |
| MAGOH | mago-nashi homolog, proliferation-associated (Drosophila) | 0.00503609 |
| CENPQ | centromere protein Q | 0.00503353 |
| ZNF430 | zinc finger protein 430 | 0.00502905 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.00502351 |
| BRIX1 | BRX1, biogenesis of ribosomes | 0.00502238 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa | 0.00501892 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0050177 |
| SAV1 | salvador family WW domain containing protein 1 | 0.00501483 |
| MRS2 | MRS2 magnesium transporter | 0.0050148 |
| NCAPH | non-SMC condensin I complex, subunit H | 0.00500931 |
| ODC1 | ornithine decarboxylase 1 | 0.00499443 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00499199 |
| VSNL1 | visinin-like 1 | 0.00498482 |
| C9ORF91 | chromosome 9 open reading frame 91 | 0.00497929 |
| ABHD17B | abhydrolase domain containing 17B | 0.0049741 |
| TSPAN6 | tetraspanin 6 | 0.00497409 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00496777 |
| CNTN1 | contactin 1 | 0.00496671 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00495944 |
| FZD7 | frizzled class receptor 7 | 0.00495755 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00495573 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00495136 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00495091 |
| KIF18A | kinesin family member 18A | 0.00495071 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00494893 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | 0.00494436 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) | 0.00494163 |
| MYBPC1 | myosin binding protein C, slow type | 0.00491642 |
| GLO1 | glyoxalase I | 0.004904 |
| RCAN1 | regulator of calcineurin 1 | 0.0048922 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) | 0.00488872 |
| STIL | SCL/TAL1 interrupting locus | 0.00488346 |
| SETMAR | SET domain and mariner transposase fusion gene | 0.00488073 |
| CAMP | cathelicidin antimicrobial peptide | 0.00487358 |
| E2F8 | E2F transcription factor 8 | 0.00487023 |
| RPP14 | ribonuclease P/MRP 14kDa subunit | 0.00485988 |
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.00485631 |
| TMEM38B | transmembrane protein 38B | 0.00485549 |
| GAP43 | growth associated protein 43 | 0.00485487 |
| MAGOHB | mago-nashi homolog B (Drosophila) | 0.00485487 |
| GPN3 | GPN-loop GTPase 3 | 0.00485142 |
| CTSG | cathepsin G | 0.00484992 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.00484981 |
| DBF4 | DBF4 zinc finger | 0.00483419 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00483108 |
| AUNIP | aurora kinase A and ninein interacting protein | 0.00483018 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00482745 |
| CST7 | cystatin F (leukocystatin) | 0.00482285 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.00481572 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00480675 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00480499 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | 0.00480374 |
| EIF4E | eukaryotic translation initiation factor 4E | 0.00480291 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0161172 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0142409 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0134095 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0129809 |
| FBLN1 | fibulin 1 | -0.0126251 |
| C3 | complement component 3 | -0.0125815 |
| KRT18 | keratin 18, type I | -0.0122364 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0112456 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0111554 |
| TP53 | tumor protein p53 | -0.0107837 |
| DCN | decorin | -0.0107166 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0105406 |
| GOLGA8H | golgin A8 family, member H | -0.0103507 |
| GPX2 | glutathione peroxidase 2 | -0.010311 |
| APOD | apolipoprotein D | -0.0102018 |
| OLFM4 | olfactomedin 4 | -0.00998273 |
| LXN | latexin | -0.00995303 |
| KYNU | kynureninase | -0.00959241 |
| KRT7 | keratin 7, type II | -0.00948329 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00945304 |
| ADIRF | adipogenesis regulatory factor | -0.00941835 |
| PERP | PERP, TP53 apoptosis effector | -0.00935442 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00929381 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0092617 |
| SESN1 | sestrin 1 | -0.00922889 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00921039 |
| MMP1 | matrix metallopeptidase 1 | -0.00918517 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00913836 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00909971 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00909313 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00909163 |
| TUBB6 | tubulin, beta 6 class V | -0.00902473 |
| KRT8 | keratin 8, type II | -0.00899964 |
| AREG | amphiregulin | -0.00899495 |
| S100A4 | S100 calcium binding protein A4 | -0.00898085 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00893085 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00879068 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00871651 |
| MVP | major vault protein | -0.00871244 |
| PLXNB2 | plexin B2 | -0.00860239 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00857935 |
| TXLNA | taxilin alpha | -0.00857797 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | -0.00855899 |
| PON2 | paraoxonase 2 | -0.00854964 |
| ASPH | aspartate beta-hydroxylase | -0.00852955 |
| LAMB1 | laminin, beta 1 | -0.00845039 |
| SIK1 | salt-inducible kinase 1 | -0.00843757 |
| KRT19 | keratin 19, type I | -0.00843729 |
| C1S | complement component 1, s subcomponent | -0.0084104 |
| ASPN | asporin | -0.00839757 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00839401 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00837334 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00836447 |
| PDGFD | platelet derived growth factor D | -0.00831402 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00823463 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | -0.00822317 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00808225 |
| MXRA5 | matrix-remodelling associated 5 | -0.00803511 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00801419 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00800575 |
| FDXR | ferredoxin reductase | -0.00795527 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00793537 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00792663 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00790166 |
| MEIS1 | Meis homeobox 1 | -0.00786853 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00780849 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00780106 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00779914 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00777524 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00776505 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00773298 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00772419 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00770321 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00769138 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00760563 |
| CFD | complement factor D (adipsin) | -0.00758159 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00756983 |
| TBX3 | T-box 3 | -0.00754625 |
| REG1A | regenerating islet-derived 1 alpha | -0.00745841 |
| AGR2 | anterior gradient 2 | -0.00740939 |
| CCNG1 | cyclin G1 | -0.00740865 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00740782 |
| PLXNC1 | plexin C1 | -0.00732242 |
| C1R | complement component 1, r subcomponent | -0.00731528 |
| CFB | complement factor B | -0.00730079 |
| IL32 | interleukin 32 | -0.00729465 |
| CTSK | cathepsin K | -0.00728269 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00727317 |
| SFXN3 | sideroflexin 3 | -0.00723252 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00722582 |
| MAP7 | microtubule-associated protein 7 | -0.00721982 |
| WDR13 | WD repeat domain 13 | -0.00721922 |
| SMAD3 | SMAD family member 3 | -0.0071991 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00719116 |
| MIR22HG | MIR22 host gene | -0.007178 |
| METRN | meteorin, glial cell differentiation regulator | -0.00717318 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00716992 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00716227 |
| ANXA4 | annexin A4 | -0.00715373 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00714696 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00714113 |
| PMP22 | peripheral myelin protein 22 | -0.00713827 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00711138 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00706531 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00704465 |
| GAS1 | growth arrest-specific 1 | -0.00703117 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.00702093 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0070202 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00701034 |
| VCAN | versican | -0.00699354 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.0069699 |
| PLPP2 | phospholipid phosphatase 2 | -0.00695016 |
| TST | thiosulfate sulfurtransferase (rhodanese) | -0.00694575 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.0068928 |
| TUBA1A | tubulin, alpha 1a | -0.0068805 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00683296 |
| SPATA20 | spermatogenesis associated 20 | -0.00683168 |
| SPP1 | secreted phosphoprotein 1 | -0.00680413 |
| RPS27L | ribosomal protein S27-like | -0.00678674 |
| ADCY9 | adenylate cyclase 9 | -0.00676656 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.00676033 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00675991 |
| GOLGA8A | golgin A8 family, member A | -0.00672091 |
| RTL8C | retrotransposon Gag like 8C | -0.006697 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.00669511 |
| TAGLN | transgelin | -0.00667489 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00666044 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00663508 |
| FILIP1L | filamin A interacting protein 1-like | -0.00656899 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00656354 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00656157 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.00655081 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00649931 |
| LAMA5 | laminin, alpha 5 | -0.00649568 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00649079 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00647782 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00644542 |
| C1RL | complement component 1, r subcomponent-like | -0.00644477 |
| FAM50A | family with sequence similarity 50, member A | -0.0064439 |
| COLEC12 | collectin sub-family member 12 | -0.00643786 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00643663 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00642542 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00641014 |
| SH3BP4 | SH3-domain binding protein 4 | -0.00638413 |
| BICC1 | BicC family RNA binding protein 1 | -0.00637414 |
| COL5A2 | collagen, type V, alpha 2 | -0.00637312 |
| ANGPTL4 | angiopoietin-like 4 | -0.00637257 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00636444 |
| TNS3 | tensin 3 | -0.00635701 |
| ITGAV | integrin, alpha V | -0.00635505 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 | -0.0063469 |
| TRIM22 | tripartite motif containing 22 | -0.00633933 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00633187 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00629787 |
| MFAP4 | microfibrillar-associated protein 4 | -0.0062713 |
| NNMT | nicotinamide N-methyltransferase | -0.00626154 |
| NOTCH1 | notch 1 | -0.00625663 |
| ANXA5 | annexin A5 | -0.00625503 |
| WDR45 | WD repeat domain 45 | -0.0062538 |
| CTSB | cathepsin B | -0.0062491 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.00624666 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00624234 |
| PLXND1 | plexin D1 | -0.00623376 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00622317 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00621451 |
| NID1 | nidogen 1 | -0.00619605 |
| MTMR11 | myotubularin related protein 11 | -0.00617449 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.00615926 |
| AXL | AXL receptor tyrosine kinase | -0.00614812 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00614061 |
| CEL | carboxyl ester lipase | -0.00611554 |
| PRKCZ | protein kinase C, zeta | -0.0061033 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00610047 |
| KRT23 | keratin 23, type I | -0.00609056 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00608664 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00608558 |
| TOB1 | transducer of ERBB2, 1 | -0.00608202 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00608051 |
| FBXO2 | F-box protein 2 | -0.0060675 |
| CCN2 | cellular communication network factor 2 | -0.00606131 |
| FAS | Fas cell surface death receptor | -0.00605523 |
| MFAP5 | microfibrillar associated protein 5 | -0.00605159 |
| CD163 | CD163 molecule | -0.00604248 |
| FBN2 | fibrillin 2 | -0.00603317 |
| ATP9A | ATPase, class II, type 9A | -0.00603245 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | -0.00603007 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0059769 |
| ACKR3 | atypical chemokine receptor 3 | -0.00596495 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00594728 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.0059425 |
| NOTCH2 | notch 2 | -0.00589573 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00589499 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00589499 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.00589188 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00586441 |
| LAMA2 | laminin, alpha 2 | -0.00585433 |
| MMP7 | matrix metallopeptidase 7 | -0.00581256 |
| SDC4 | syndecan 4 | -0.00580655 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | -0.00577162 |
| PLIN2 | perilipin 2 | -0.00576781 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00574603 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00574596 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00574441 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00574311 |
| MID1 | midline 1 | -0.00573687 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00573154 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.0057212 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00572097 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -0.00570329 |
| DACH1 | dachshund family transcription factor 1 | -0.00567615 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | -0.00567356 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00567158 |
| MARCKSL1 | MARCKS-like 1 | -0.00566933 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00566378 |
| ALB | albumin | -0.00565546 |
| PLN | phospholamban | -0.00565148 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00564593 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00563466 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00562396 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00559042 |
| CEP170 | centrosomal protein 170kDa | -0.00558412 |
| MMP11 | matrix metallopeptidase 11 | -0.00558197 |
| FBLN2 | fibulin 2 | -0.00556851 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0055671 |
| TMEM131 | transmembrane protein 131 | -0.00556628 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00554562 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00553498 |
| FZD2 | frizzled class receptor 2 | -0.00552719 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | -0.00550228 |
| FBLN5 | fibulin 5 | -0.00549788 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | -0.00548414 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0054832 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.0054776 |
| ELAC2 | elaC ribonuclease Z 2 | -0.00546851 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00546659 |
| MOK | MOK protein kinase | -0.00545052 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | -0.00543418 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00542472 |
| ANGPTL2 | angiopoietin-like 2 | -0.00542289 |
| MXD4 | MAX dimerization protein 4 | -0.00542065 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00539477 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -0.00539066 |
| LOXL1 | lysyl oxidase-like 1 | -0.00536592 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00535804 |
| AHR | aryl hydrocarbon receptor | -0.00534046 |
| UROD | uroporphyrinogen decarboxylase | -0.00531311 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00529966 |
| PNMA1 | paraneoplastic Ma antigen 1 | -0.00529955 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0052826 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00528025 |
