TPM2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description tropomyosin 2 (beta)|This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 7169)
External Link https://ncbi.nlm.nih.gov/gene/7169
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Genes

499 genes differentially expressed following the TPM2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0226833
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.016526
CIAO3 cytosolic iron-sulfur assembly component 3 0.0132609
RBM34 RNA binding motif protein 34 0.0128698
MAP7 microtubule-associated protein 7 0.01239
CEMIP cell migration inducing protein, hyaluronan binding 0.0120718
ANO10 anoctamin 10 0.01185
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.011635
HSPA1A heat shock 70kDa protein 1A 0.0104659
BTF3P11 basic transcription factor 3 pseudogene 11 0.010343
PRAME preferentially expressed antigen in melanoma 0.0101136
KRT13 keratin 13, type I 0.00993401
MAGEA3 melanoma antigen family A3 0.00984963
ABLIM1 actin binding LIM protein 1 0.0097072
SPRR3 small proline-rich protein 3 0.00952614
RGS13 regulator of G-protein signaling 13 0.00947544
PRKCA protein kinase C, alpha 0.00943054
COCH cochlin 0.00908464
TP53I3 tumor protein p53 inducible protein 3 0.00904328
DRAM1 DNA-damage regulated autophagy modulator 1 0.00896068
ZDHHC6 zinc finger, DHHC-type containing 6 0.00891904
SMAGP small cell adhesion glycoprotein 0.00887291
PTK2 protein tyrosine kinase 2 0.00887077
RHCG Rh family, C glycoprotein 0.00885141
RPL14 ribosomal protein L14 0.0088495
MAL mal, T-cell differentiation protein 0.00874543
GDI2 GDP dissociation inhibitor 2 0.008609
CRISP3 cysteine-rich secretory protein 3 0.00859398
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00859147
TCL1A T-cell leukemia/lymphoma 1A 0.00858769
ADM adrenomedullin 0.00842725
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00842146
DLK1 delta-like 1 homolog (Drosophila) 0.00834955
CDH13 cadherin 13 0.00830972
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.0082874
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00824337
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00816482
H1-0 H1.0 linker histone 0.00814123
CD79B CD79b molecule, immunoglobulin-associated beta 0.00809775
SERP1 stress-associated endoplasmic reticulum protein 1 0.00800471
NEBL nebulette 0.00796004
RPS26 ribosomal protein S26 0.00793201
GRB7 growth factor receptor-bound protein 7 0.00783546
KRT18 keratin 18, type I 0.00782116
KRT6A keratin 6A, type II 0.00779011
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 0.00778264
TSC22D1 TSC22 domain family, member 1 0.00774859
ISG20 interferon stimulated exonuclease gene 20kDa 0.00772332
S100A8 S100 calcium binding protein A8 0.00771049
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.0077049
POU4F1 POU class 4 homeobox 1 0.00755688
CD52 CD52 molecule 0.00752026
CXCL13 chemokine (C-X-C motif) ligand 13 0.00741246
NOP53 NOP53 ribosome biogenesis factor 0.00738754
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00734986
ICA1 islet cell autoantigen 1, 69kDa 0.00729297
MALL mal, T-cell differentiation protein-like 0.00728874
IGBP1 immunoglobulin (CD79A) binding protein 1 0.0072634
ECM1 extracellular matrix protein 1 0.00725326
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0071841
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00714942
IGFBP6 insulin-like growth factor binding protein 6 0.00713223
BMP7 bone morphogenetic protein 7 0.00711577
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00709162
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.00707405
YPEL5 yippee-like 5 (Drosophila) 0.00703728
YBX1 Y box binding protein 1 0.00701468
PAX5 paired box 5 0.00701048
HSPA8 heat shock 70kDa protein 8 0.00700218
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00699511
SGK1 serum/glucocorticoid regulated kinase 1 0.00697486
THOC5 THO complex 5 0.00694514
TPD52L1 tumor protein D52-like 1 0.00694375
LTA4H leukotriene A4 hydrolase 0.00691946
KRT81 keratin 81, type II 0.00689347
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00688277
WEE1 WEE1 G2 checkpoint kinase 0.00684155
KRT6B keratin 6B, type II 0.00679936
MAP3K7CL MAP3K7 C-terminal like 0.00678241
VEGFC vascular endothelial growth factor C 0.00677821
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00675015
SOX11 SRY (sex determining region Y)-box 11 0.00672202
RAB29 RAB29, member RAS oncogene family 0.00671092
JUNB jun B proto-oncogene 0.00669301
S100A10 S100 calcium binding protein A10 0.0066182
CD19 CD19 molecule 0.00661696
ADGRE1 adhesion G protein-coupled receptor E1 0.0066133
DAXX death-domain associated protein 0.00656266
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.00656212
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00654245
PLCB4 phospholipase C, beta 4 0.00651105
MTIF2 mitochondrial translational initiation factor 2 0.0065019
SOX10 SRY (sex determining region Y)-box 10 0.00649507
CD9 CD9 molecule 0.00649201
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.00647696
FCMR Fc fragment of IgM receptor 0.00646636
BABAM2 BRISC and BRCA1 A complex member 2 0.00645672
QPCT glutaminyl-peptide cyclotransferase 0.00643849
EIF3F eukaryotic translation initiation factor 3, subunit F 0.00639325
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00638479
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00637317
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.0063637
PGD phosphogluconate dehydrogenase 0.00636203
FLT3 fms-related tyrosine kinase 3 0.00635697
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00635319
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00634959
IL32 interleukin 32 0.00634812
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00634683
KRT7 keratin 7, type II 0.00630297
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00627163
ARF3 ADP-ribosylation factor 3 0.00625662
S100A7 S100 calcium binding protein A7 0.00625047
HIGD2A HIG1 hypoxia inducible domain family, member 2A 0.00623929
FABP6 fatty acid binding protein 6, ileal 0.00623637
ALCAM activated leukocyte cell adhesion molecule 0.00623586
SEC13 SEC13 homolog (S. cerevisiae) 0.00621289
UFC1 ubiquitin-fold modifier conjugating enzyme 1 0.00619039
EIF3L eukaryotic translation initiation factor 3, subunit L 0.00618314
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.00617979
ANKRD28 ankyrin repeat domain 28 0.00617091
CD27 CD27 molecule 0.00613276
STON1 stonin 1 0.00611528
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.00611499
GBP2 guanylate binding protein 2, interferon-inducible 0.00609294
ODC1 ornithine decarboxylase 1 0.00609056
UPK1B uroplakin 1B 0.0060748
TMPRSS11E transmembrane protease, serine 11E 0.00606618
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.00605941
RPS17 ribosomal protein S17 0.00604112
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00603463
GM2A GM2 ganglioside activator 0.00603359
PF4 platelet factor 4 0.00603201
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00603045
TLE4 transducin-like enhancer of split 4 0.00600855
SPRR2B small proline-rich protein 2B 0.00600829
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00598847
GRWD1 glutamate-rich WD repeat containing 1 0.00598312
CALB1 calbindin 1, 28kDa 0.00598249
POU2AF1 POU class 2 associating factor 1 0.00597172
NAGK N-acetylglucosamine kinase 0.00596031
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00595776
WSB2 WD repeat and SOCS box containing 2 0.00595592
RAB13 RAB13, member RAS oncogene family 0.00594959
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0059464
VPREB3 pre-B lymphocyte 3 0.00594542
KIAA0226L KIAA0226-like 0.0059294
ABHD5 abhydrolase domain containing 5 0.00591643
SCEL sciellin 0.00589762
LETMD1 LETM1 domain containing 1 0.00588073
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.0058806
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.0058528
OFD1 oral-facial-digital syndrome 1 0.00583817
NARF nuclear prelamin A recognition factor 0.00583681
PKP1 plakophilin 1 0.00583421
STATH statherin 0.00582842
GCH1 GTP cyclohydrolase 1 0.00580846
CRELD1 cysteine-rich with EGF-like domains 1 0.00580651
NIPSNAP1 nipsnap homolog 1 (C. elegans) 0.00580253
ERGIC3 ERGIC and golgi 3 0.00580002
WBP2 WW domain binding protein 2 0.00578805
LMCD1 LIM and cysteine-rich domains 1 0.00577099
PRODH proline dehydrogenase (oxidase) 1 0.00575719
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00575552
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00575047
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.00571828
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00571658
NCOA4 nuclear receptor coactivator 4 0.00571364
LBH limb bud and heart development 0.00571166
MRPL33 mitochondrial ribosomal protein L33 0.00570889
PARL presenilin associated, rhomboid-like 0.00569302
GPNMB glycoprotein (transmembrane) nmb 0.00568585
EIF3G eukaryotic translation initiation factor 3, subunit G 0.00567293
DRG1 developmentally regulated GTP binding protein 1 0.00566429
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.00565401
PDE4B phosphodiesterase 4B, cAMP-specific 0.00565362
HAVCR1 hepatitis A virus cellular receptor 1 0.00565021
NUPR1 nuclear protein, transcriptional regulator, 1 0.00564834
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 0.00564653
C3 complement component 3 0.0056355
F12 coagulation factor XII (Hageman factor) 0.00563438
TNIP1 TNFAIP3 interacting protein 1 0.00563059
NDRG1 N-myc downstream regulated 1 0.00562113
RAB11FIP3 RAB11 family interacting protein 3 (class II) 0.00561133
AMACR alpha-methylacyl-CoA racemase 0.00560915
BCR breakpoint cluster region 0.00560244
ABHD4 abhydrolase domain containing 4 0.00559512
RPL36 ribosomal protein L36 0.00559346
AIP aryl hydrocarbon receptor interacting protein 0.00558863
MVP major vault protein 0.00558713
COG7 component of oligomeric golgi complex 7 0.00558142
CLIC3 chloride intracellular channel 3 0.00558125
SIK1 salt-inducible kinase 1 0.00556462
STX7 syntaxin 7 0.00556102
MFAP3L microfibrillar-associated protein 3-like 0.00555179
EIF3H eukaryotic translation initiation factor 3, subunit H 0.0055412
DEPTOR DEP domain containing MTOR-interacting protein 0.00553064
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00552022
HBB hemoglobin, beta 0.00551908
EPHB2 EPH receptor B2 0.00551245
SOD2 superoxide dismutase 2, mitochondrial 0.00551114
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00550987
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.00550685
CCNG1 cyclin G1 0.00550125
GAL galanin/GMAP prepropeptide 0.00549704
ATOX1 antioxidant 1 copper chaperone 0.00549623
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00545994
TACC2 transforming, acidic coiled-coil containing protein 2 0.00545588
PRKD3 protein kinase D3 0.00542204
MT1X metallothionein 1X 0.00542015
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00541817
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.0054181
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.005418
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00541126
ACAN aggrecan 0.00541101
PDE10A phosphodiesterase 10A 0.00539757
C1ORF105 chromosome 1 open reading frame 105 0.00538775
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 0.00537022
EIF4B eukaryotic translation initiation factor 4B 0.00536296
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.00535615
CST3 cystatin C 0.00535425
FUCA1 fucosidase, alpha-L- 1, tissue 0.00535402
C1S complement component 1, s subcomponent 0.00534915
DGKA diacylglycerol kinase, alpha 80kDa 0.00534605
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00533755
CNN1 calponin 1, basic, smooth muscle 0.00533064
LRRC31 leucine rich repeat containing 31 0.00532577
SAP30BP SAP30 binding protein 0.00532127
SPRR1A small proline-rich protein 1A 0.0053205
AIM2 absent in melanoma 2 0.00531684
CYB5R2 cytochrome b5 reductase 2 0.00531332
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.00531216
RPL29 ribosomal protein L29 0.00531
CHI3L2 chitinase 3-like 2 0.00530593
UFD1 ubiquitin recognition factor in ER associated degradation 1 0.0053046
CSTA cystatin A (stefin A) 0.00530106
VAMP8 vesicle-associated membrane protein 8 0.00529042
NAP1L1 nucleosome assembly protein 1-like 1 0.00528401
TMEM43 transmembrane protein 43 0.00527917
PDLIM1 PDZ and LIM domain 1 0.00527278
ACP1 acid phosphatase 1, soluble 0.00526257
OSBPL10 oxysterol binding protein-like 10 0.00526158
R3HDM4 R3H domain containing 4 0.00525506
SPRR1B small proline-rich protein 1B 0.00524908
DSG3 desmoglein 3 0.00524813
MPV17 MpV17 mitochondrial inner membrane protein 0.00524264
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.00524014
RFTN1 raftlin, lipid raft linker 1 0.00523676
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.00523133
AGBL5 ATP/GTP binding protein-like 5 0.00522585

decreased expression

Symbol Name Standardized Value
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0145918
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0136404
SEPP1 selenoprotein P, plasma, 1 -0.0130306
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0127229
SLIT2 slit homolog 2 (Drosophila) -0.0123748
LAMP5 lysosomal-associated membrane protein family, member 5 -0.0123151
NEFH neurofilament, heavy polypeptide -0.0114178
MBL2 mannose-binding lectin (protein C) 2, soluble -0.0104686
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0103529
CPM carboxypeptidase M -0.0102014
ESR1 estrogen receptor 1 -0.0100099
CLEC2B C-type lectin domain family 2, member B -0.00993466
EFNB2 ephrin-B2 -0.00993274
RBBP8 retinoblastoma binding protein 8 -0.00984084
FCGBP Fc fragment of IgG binding protein -0.00961289
PEG3 paternally expressed 3 -0.00955517
SPIN1 spindlin 1 -0.009505
KCTD12 potassium channel tetramerization domain containing 12 -0.00948425
CP ceruloplasmin (ferroxidase) -0.00947431
FRZB frizzled-related protein -0.00938477
TMPRSS4 transmembrane protease, serine 4 -0.00933724
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00933495
GPM6B glycoprotein M6B -0.00933469
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00924276
SDC2 syndecan 2 -0.00912856
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00910192
A2M alpha-2-macroglobulin -0.00909223
KLK5 kallikrein-related peptidase 5 -0.00906623
TYROBP TYRO protein tyrosine kinase binding protein -0.00905738
NELL1 NEL-like 1 (chicken) -0.00904126
TSPAN8 tetraspanin 8 -0.00892172
COLEC12 collectin sub-family member 12 -0.00892
IFI44L interferon-induced protein 44-like -0.00883037
SCGB1D2 secretoglobin, family 1D, member 2 -0.00880984
SEPTIN10 septin 10 -0.00876523
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.00873172
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00868923
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00867708
ARHGAP29 Rho GTPase activating protein 29 -0.00864653
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0086045
WSB1 WD repeat and SOCS box containing 1 -0.00851651
SPARCL1 SPARC-like 1 (hevin) -0.00849124
PER3 period circadian clock 3 -0.00846249
BST2 bone marrow stromal cell antigen 2 -0.00845014
BRD2 bromodomain containing 2 -0.00844732
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -0.00841403
NXN nucleoredoxin -0.00840698
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00840066
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00829602
RCAN2 regulator of calcineurin 2 -0.00823829
RDX radixin -0.00820333
CALD1 caldesmon 1 -0.00818063
LY6E lymphocyte antigen 6 complex, locus E -0.0081664
CFI complement factor I -0.00816357
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.0081311
PLXNC1 plexin C1 -0.00813056
COL3A1 collagen, type III, alpha 1 -0.00812695
MYLK myosin light chain kinase -0.00812502
PUF60 poly-U binding splicing factor 60KDa -0.00809343
CTSZ cathepsin Z -0.00808414
GUCY1B3 guanylate cyclase 1, soluble, beta 3 -0.00806435
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00806226
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00805202
OLFM1 olfactomedin 1 -0.00804939
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00804362
HMGB1 high mobility group box 1 -0.00802754
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00802359
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00800121
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00793649
PLS1 plastin 1 -0.0079347
FGL2 fibrinogen-like 2 -0.00791983
CD93 CD93 molecule -0.00788602
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00787115
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00786901
CTBP1 C-terminal binding protein 1 -0.00786377
RNF38 ring finger protein 38 -0.00781394
SCGB2A1 secretoglobin, family 2A, member 1 -0.00780595
WASL Wiskott-Aldrich syndrome-like -0.0078007
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00777392
SMC1A structural maintenance of chromosomes 1A -0.00777255
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00776913
PNMA1 paraneoplastic Ma antigen 1 -0.00774364
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00770802
GAS2 growth arrest-specific 2 -0.00769996
PTCH1 patched 1 -0.00764258
NID2 nidogen 2 (osteonidogen) -0.00756247
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00755829
IFI44 interferon-induced protein 44 -0.00755384
CAV1 caveolin 1, caveolae protein, 22kDa -0.00751435
BRD4 bromodomain containing 4 -0.00749527
STK10 serine/threonine kinase 10 -0.00747631
NBPF10 neuroblastoma breakpoint family, member 10 -0.00745916
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -0.00744347
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00744123
EFHD1 EF-hand domain family, member D1 -0.00743653
CD300A CD300a molecule -0.00741725
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00741624
TPD52 tumor protein D52 -0.00740124
KAZN kazrin, periplakin interacting protein -0.00739097
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00736172
SCRIB scribbled planar cell polarity protein -0.00735824
ZBTB20 zinc finger and BTB domain containing 20 -0.00732723
NFIB nuclear factor I/B -0.00731991
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00731065
TGFBR3 transforming growth factor, beta receptor III -0.00727972
TRIP13 thyroid hormone receptor interactor 13 -0.00727757
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.00727465
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00726436
TMEM106C transmembrane protein 106C -0.00723468
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00723277
MTERF3 mitochondrial transcription termination factor 3 -0.00723066
CCR1 chemokine (C-C motif) receptor 1 -0.00721551
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00720213
PTN pleiotrophin -0.00717456
KIF3A kinesin family member 3A -0.00712342
CPVL carboxypeptidase, vitellogenic-like -0.00709961
SFRP4 secreted frizzled-related protein 4 -0.00706631
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.00706187
BCHE butyrylcholinesterase -0.00705355
CCL13 chemokine (C-C motif) ligand 13 -0.00702347
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -0.00702303
ATAD2 ATPase family, AAA domain containing 2 -0.00702004
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -0.00700258
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -0.00697281
PRDX2 peroxiredoxin 2 -0.00697172
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00697055
SPRY2 sprouty homolog 2 (Drosophila) -0.00695951
SST somatostatin -0.00693902
PROM1 prominin 1 -0.00691882
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00691417
GCLM glutamate-cysteine ligase, modifier subunit -0.00691408
NSD2 nuclear receptor binding SET domain protein 2 -0.00690709
BBX bobby sox homolog (Drosophila) -0.00685713
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00685364
FPR3 formyl peptide receptor 3 -0.0068482
ADCY7 adenylate cyclase 7 -0.00684372
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00679448
COL6A2 collagen, type VI, alpha 2 -0.00678383
RAB20 RAB20, member RAS oncogene family -0.00675113
STK3 serine/threonine kinase 3 -0.00670817
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00668303
MGP matrix Gla protein -0.00664477
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00664167
DENND1B DENN/MADD domain containing 1B -0.0066398
SLBP stem-loop binding protein -0.00663819
TACC1 transforming, acidic coiled-coil containing protein 1 -0.00663604
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00662066
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00662037
WWTR1 WW domain containing transcription regulator 1 -0.00660921
FRMD4B FERM domain containing 4B -0.00660698
BARD1 BRCA1 associated RING domain 1 -0.00659549
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -0.00659485
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00659173
CALCA calcitonin-related polypeptide alpha -0.00658226
KIAA0232 KIAA0232 -0.00653503
H2AX H2A.X variant histone -0.00653442
HIP1 huntingtin interacting protein 1 -0.00653012
NIPSNAP2 nipsnap homolog 2 -0.00651057
MFSD10 major facilitator superfamily domain containing 10 -0.00650016
SLA Src-like-adaptor -0.00647568
TYMS thymidylate synthetase -0.00646321
AOC1 amine oxidase, copper containing 1 -0.00645368
MXRA5 matrix-remodelling associated 5 -0.00644841
MCAM melanoma cell adhesion molecule -0.00644648
INSIG1 insulin induced gene 1 -0.00644599
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00644124
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00642469
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00640731
TXN thioredoxin -0.0063939
TFDP1 transcription factor Dp-1 -0.00637403
F2R coagulation factor II (thrombin) receptor -0.00637342
PRNP prion protein -0.00636715
PKP2 plakophilin 2 -0.00636638
SREBF1 sterol regulatory element binding transcription factor 1 -0.00636606
HCRTR1 hypocretin (orexin) receptor 1 -0.00636171
KRT23 keratin 23, type I -0.00636129
CD14 CD14 molecule -0.00635902
CAVIN1 caveolae associated protein 1 -0.00635185
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00634887
EDNRA endothelin receptor type A -0.00632901
LST1 leukocyte specific transcript 1 -0.00630994
SPP1 secreted phosphoprotein 1 -0.00630913
PBK PDZ binding kinase -0.00630491
PLXDC1 plexin domain containing 1 -0.00629108
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.0062874
SYNGR3 synaptogyrin 3 -0.0062753
TMEM70 transmembrane protein 70 -0.00627452
OLFML2A olfactomedin-like 2A -0.00627403
KLF13 Kruppel-like factor 13 -0.00626216
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.0062598
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00625832
MYO5C myosin VC -0.00624712
PER2 period circadian clock 2 -0.006238
EXPH5 exophilin 5 -0.00622111
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 -0.0062189
CRABP2 cellular retinoic acid binding protein 2 -0.00621335
ACTN4 actinin, alpha 4 -0.00620456
IGF1 insulin-like growth factor 1 (somatomedin C) -0.0061987
NEMP1 nuclear envelope integral membrane protein 1 -0.00618829
PIR pirin (iron-binding nuclear protein) -0.00618703
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.00618133
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00617735
COL4A5 collagen, type IV, alpha 5 -0.00616209
BCAR3 breast cancer anti-estrogen resistance 3 -0.0061604
ADGRG2 adhesion G protein-coupled receptor G2 -0.00615381
MGLL monoglyceride lipase -0.00614533
HTRA1 HtrA serine peptidase 1 -0.00614492
CCL8 chemokine (C-C motif) ligand 8 -0.00613899
RXRA retinoid X receptor, alpha -0.0061371
ANKRD11 ankyrin repeat domain 11 -0.00612855
ADGRL2 adhesion G protein-coupled receptor L2 -0.0061255
COL14A1 collagen, type XIV, alpha 1 -0.00612542
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.00612456
TXNIP thioredoxin interacting protein -0.00611793
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.00608653
KLF5 Kruppel-like factor 5 (intestinal) -0.00608027
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00607738
NUP210 nucleoporin 210kDa -0.00607059
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.0060677
LPIN2 lipin 2 -0.00606753
PALMD palmdelphin -0.0060585
SNAP25 synaptosomal-associated protein, 25kDa -0.00605539
DPYD dihydropyrimidine dehydrogenase -0.0060552
PCLAF PCNA clamp associated factor -0.0060457
ASRGL1 asparaginase like 1 -0.00604399
SELENBP1 selenium binding protein 1 -0.00603583
FERMT2 fermitin family member 2 -0.00603132
GLOD4 glyoxalase domain containing 4 -0.00601924
ADD1 adducin 1 (alpha) -0.00600476
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00599835
ISOC1 isochorismatase domain containing 1 -0.00598728
C1QB complement component 1, q subcomponent, B chain -0.00598595
RBM12B RNA binding motif protein 12B -0.0059715
TRPS1 trichorhinophalangeal syndrome I -0.0059403
CELF2 CUGBP, Elav-like family member 2 -0.00592824
MATN2 matrilin 2 -0.00591746
CKS1B CDC28 protein kinase regulatory subunit 1B -0.00590744
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.00590144
TMEM176B transmembrane protein 176B -0.00589998
MRPS28 mitochondrial ribosomal protein S28 -0.00589829
ANXA3 annexin A3 -0.00589651
ITGA6 integrin, alpha 6 -0.00589532
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.00589527
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00589189
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -0.00588989
SACS sacsin molecular chaperone -0.00588895
PCNXL4 pecanex-like 4 (Drosophila) -0.00588736
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00585662
FNBP1 formin binding protein 1 -0.00585568
PNMA8A PNMA family member 8A -0.0058553