TPM2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description tropomyosin 2 (beta)|This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 7169)
External Link http://www.ncbi.nlm.nih.gov/gene/7169
Similar Terms
Downloads & Tools

Genes

369 interacting proteins for TPM2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABLIM1 actin binding LIM protein 1
ABLIM3 actin binding LIM protein family, member 3
ACTA1 actin, alpha 1, skeletal muscle
ACTB actin, beta
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADRBK1 adrenergic, beta, receptor kinase 1
AHCYL1 adenosylhomocysteinase-like 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA2 annexin A2
ANXA6 annexin A6
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATAD3A ATPase family, AAA domain containing 3A
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
BCLAF1 BCL2-associated transcription factor 1
C1QBP complement component 1, q subcomponent binding protein
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CAPZB capping protein (actin filament) muscle Z-line, beta
CASC5 cancer susceptibility candidate 5
CATSPER1 cation channel, sperm associated 1
CATSPER2 cation channel, sperm associated 2
CATSPER3 cation channel, sperm associated 3
CATSPER4 cation channel, sperm associated 4
CATSPERB catsper channel auxiliary subunit beta
CATSPERD catsper channel auxiliary subunit delta
CATSPERG catsper channel auxiliary subunit gamma
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBR1 carbonyl reductase 1
CCM2L cerebral cavernous malformation 2-like
CD59 CD59 molecule, complement regulatory protein
CFL1 cofilin 1 (non-muscle)
CFL2 cofilin 2 (muscle)
CLIC2 chloride intracellular channel 2
CNGA1 cyclic nucleotide gated channel alpha 1
CNGB1 cyclic nucleotide gated channel beta 1
COG5 component of oligomeric golgi complex 5
COG7 component of oligomeric golgi complex 7
CORO1B coronin, actin binding protein, 1B
CORO1C coronin, actin binding protein, 1C
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTTN cortactin
DAPK3 death-associated protein kinase 3
DBN1 drebrin 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DLD dihydrolipoamide dehydrogenase
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DSN1 DSN1, MIS12 kinetochore complex component
DST dystonin
DSTN destrin (actin depolymerizing factor)
DUT deoxyuridine triphosphatase
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNLL1 dynein, light chain, LC8-type 1
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1G eukaryotic translation elongation factor 1 gamma
EEF2 eukaryotic translation elongation factor 2
EGFR epidermal growth factor receptor
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4A3 eukaryotic translation initiation factor 4A3
EIF4B eukaryotic translation initiation factor 4B
EPB41 erythrocyte membrane protein band 4.1
EPPK1 epiplakin 1
EPS15 epidermal growth factor receptor pathway substrate 15
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EXOC3 exocyst complex component 3
EXOC4 exocyst complex component 4
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FLNB filamin B, beta
FOLR1 folate receptor 1 (adult)
FSCN1 fascin actin-bundling protein 1
FUS FUS RNA binding protein
GANAB glucosidase, alpha; neutral AB
GMFB glia maturation factor, beta
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GRB2 growth factor receptor-bound protein 2
GRWD1 glutamate-rich WD repeat containing 1
GSN gelsolin
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HIST1H2BH histone cluster 1, H2bh
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HIST2H2AA4 histone cluster 2, H2aa4
HMGB1 high mobility group box 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSBP1 heat shock factor binding protein 1
HSF1 heat shock transcription factor 1
HSF2 heat shock transcription factor 2
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTRA1 HtrA serine peptidase 1
ILF3 interleukin enhancer binding factor 3, 90kDa
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JUN jun proto-oncogene
KIFC3 kinesin family member C3
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT7 keratin 7, type II
KRT8 keratin 8, type II
LIMA1 LIM domain and actin binding 1
LMNA lamin A/C
LMO7 LIM domain 7
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LRRK2 leucine-rich repeat kinase 2
LUC7L2 LUC7-like 2 (S. cerevisiae)
LUZP1 leucine zipper protein 1
MAST2 microtubule associated serine/threonine kinase 2
MATR3 matrin 3
MCC mutated in colorectal cancers
MCOLN1 mucolipin 1
MCOLN2 mucolipin 2
MCOLN3 mucolipin 3
MISP mitotic spindle positioning
MPRIP myosin phosphatase Rho interacting protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH10 myosin, heavy chain 10, non-muscle
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO1A myosin IA
MYO1B myosin IB
MYO1C myosin IC
MYO3B myosin IIIB
MYO6 myosin VI
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NDC80 NDC80 kinetochore complex component
NDE1 nudE neurodevelopment protein 1
NDEL1 nudE neurodevelopment protein 1-like 1
NEXN nexilin (F actin binding protein)
NONO non-POU domain containing, octamer-binding
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUCLEOLIN nucleolin multifunctional protein
NUF2 NUF2, NDC80 kinetochore complex component
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
ORAI1 ORAI calcium release-activated calcium modulator 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PABPC1 poly(A) binding protein, cytoplasmic 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAWR PRKC, apoptosis, WT1, regulator
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PDCD6 programmed cell death 6
PDLIM7 PDZ and LIM domain 7 (enigma)
PHGDH phosphoglycerate dehydrogenase
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKM pyruvate kinase, muscle
PLEC plectin
PLS3 plastin 3
PMF1 polyamine-modulated factor 1
POC1A POC1 centriolar protein A
POC1B POC1 centriolar protein B
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R18 protein phosphatase 1, regulatory subunit 18
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRDX1 peroxiredoxin 1
PRKCSH protein kinase C substrate 80K-H
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT5 protein arginine methyltransferase 5
PTBP1 polypyrimidine tract binding protein 1
PTMS parathymosin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PYGM phosphorylase, glycogen, muscle
RACGAP1 Rac GTPase activating protein 1
RAI14 retinoic acid induced 14
RBBP7 retinoblastoma binding protein 7
RCC2 regulator of chromosome condensation 2
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RPL10 ribosomal protein L10
RPL12 ribosomal protein L12
RPL18 ribosomal protein L18
RPL18A ribosomal protein L18a
RPL21 ribosomal protein L21
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL3 ribosomal protein L3
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL35A ribosomal protein L35a
RPL36 ribosomal protein L36
RPL4 ribosomal protein L4
RPL7 ribosomal protein L7
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS18 ribosomal protein S18
RPS20 ribosomal protein S20
RPS23 ribosomal protein S23
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS28 ribosomal protein S28
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS5 ribosomal protein S5
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RRAD Ras-related associated with diabetes
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
RYR3 ryanodine receptor 3
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
S100A6 S100 calcium binding protein A6
SAFB2 scaffold attachment factor B2
SCIN scinderin
SERBP1 SERPINE1 mRNA binding protein 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SF3B2 splicing factor 3b, subunit 2, 145kDa
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SKIL SKI-like proto-oncogene
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNAPIN SNAP-associated protein
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SOS1 son of sevenless homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SPC24 SPC24, NDC80 kinetochore complex component
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SQSTM1 sequestosome 1
SRI sorcin
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRSF10 serine/arginine-rich splicing factor 10
SRXN1 sulfiredoxin 1
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STIM1 stromal interaction molecule 1
STMN1 stathmin 1
STOM stomatin
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SVIL supervillin
SYNPO synaptopodin
TACC3 transforming, acidic coiled-coil containing protein 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK2 TAO kinase 2
THAP11 THAP domain containing 11
THRAP3 thyroid hormone receptor associated protein 3
TIAF1 TGFB1-induced anti-apoptotic factor 1
TMOD3 tropomodulin 3 (ubiquitous)
TPCN1 two pore segment channel 1
TPCN2 two pore segment channel 2
TPM1 tropomyosin 1 (alpha)
TPM3 tropomyosin 3
TPM4 tropomyosin 4
TRDN triadin
TRHDE thyrotropin-releasing hormone degrading enzyme
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA1B tubulin, alpha 1b
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
TUFM Tu translation elongation factor, mitochondrial
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBB ubiquitin B
UBC ubiquitin C
UGDH UDP-glucose 6-dehydrogenase
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VIM vimentin
WDR1 WD repeat domain 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6