TPR Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description translocated promoter region, nuclear basket protein|This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7175)
External Link https://ncbi.nlm.nih.gov/gene/7175
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Genes

499 genes differentially expressed following the TPR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL14 chemokine (C-X-C motif) ligand 14 0.0109276
PDGFD platelet derived growth factor D 0.00840668
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00792269
RGS5 regulator of G-protein signaling 5 0.00789898
LGALS1 lectin, galactoside-binding, soluble, 1 0.00762733
HSPB8 heat shock 22kDa protein 8 0.00760742
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00752845
C3ORF14 chromosome 3 open reading frame 14 0.00742307
CPE carboxypeptidase E 0.00725606
STK10 serine/threonine kinase 10 0.00721063
CPB1 carboxypeptidase B1 (tissue) 0.00719269
CCNB2 cyclin B2 0.00718397
CD36 CD36 molecule (thrombospondin receptor) 0.00717786
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00714368
DYNLL1 dynein, light chain, LC8-type 1 0.0071435
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00712701
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00708026
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00703474
MAOA monoamine oxidase A 0.00688818
TSPAN12 tetraspanin 12 0.00683191
KRT20 keratin 20, type I 0.00683071
ADIRF adipogenesis regulatory factor 0.00676816
MYH11 myosin, heavy chain 11, smooth muscle 0.00670075
FST follistatin 0.0065745
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.00653493
GCG glucagon 0.00647684
PLS3 plastin 3 0.00640175
LCN2 lipocalin 2 0.00633404
ARHGAP29 Rho GTPase activating protein 29 0.0062819
MAP7 microtubule-associated protein 7 0.00627605
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.00625387
A2M alpha-2-macroglobulin 0.00610624
REG3A regenerating islet-derived 3 alpha 0.00603407
PLIN2 perilipin 2 0.00599228
RELN reelin 0.00598087
CD320 CD320 molecule 0.0059663
DES desmin 0.00596391
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00589527
TPSAB1 tryptase alpha/beta 1 0.00588424
SST somatostatin 0.00587545
CLEC3B C-type lectin domain family 3, member B 0.00576928
MGLL monoglyceride lipase 0.00574967
AGTR1 angiotensin II receptor, type 1 0.00573651
RTN2 reticulon 2 0.00572803
TGFBR3 transforming growth factor, beta receptor III 0.00571096
KAZN kazrin, periplakin interacting protein 0.00567534
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0056751
MAN2A1 mannosidase, alpha, class 2A, member 1 0.00567282
ADGRF5 adhesion G protein-coupled receptor F5 0.00565589
FABP4 fatty acid binding protein 4, adipocyte 0.00563249
PRUNE2 prune homolog 2 (Drosophila) 0.00562642
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00562541
PKP2 plakophilin 2 0.00562428
CTBP2 C-terminal binding protein 2 0.0056101
ANKRD11 ankyrin repeat domain 11 0.00560193
HYOU1 hypoxia up-regulated 1 0.00559632
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.00557283
INSM1 insulinoma-associated 1 0.00556424
PDLIM3 PDZ and LIM domain 3 0.00554393
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.00554032
CRY1 cryptochrome circadian clock 1 0.00553281
STAG2 stromal antigen 2 0.00552744
NKG7 natural killer cell granule protein 7 0.00550574
ADGRL2 adhesion G protein-coupled receptor L2 0.0055029
ANGPTL2 angiopoietin-like 2 0.00550148
USP22 ubiquitin specific peptidase 22 0.00547086
APOLD1 apolipoprotein L domain containing 1 0.00546594
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00546388
REG1A regenerating islet-derived 1 alpha 0.00545071
ADGRG6 adhesion G protein-coupled receptor G6 0.0054403
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00539829
MMP2 matrix metallopeptidase 2 0.00535799
SEPTIN7 septin 7 0.00534359
TAGLN transgelin 0.00530826
EXPH5 exophilin 5 0.00527633
ADCY9 adenylate cyclase 9 0.00527129
TNS1 tensin 1 0.00526573
PDPK1 3-phosphoinositide dependent protein kinase 1 0.00524959
ZBTB16 zinc finger and BTB domain containing 16 0.00524927
CLCA1 chloride channel accessory 1 0.00522834
NPY1R neuropeptide Y receptor Y1 0.00522753
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.00522318
SPINK1 serine peptidase inhibitor, Kazal type 1 0.0052119
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00520811
CENPE centromere protein E, 312kDa 0.00520518
ARG2 arginase 2 0.00518551
MXRA7 matrix-remodelling associated 7 0.00518213
TTC39A tetratricopeptide repeat domain 39A 0.00517898
NOTCH1 notch 1 0.00515033
RYBP RING1 and YY1 binding protein 0.00512399
ASPN asporin 0.00512168
VWF von Willebrand factor 0.00511615
SPEN spen family transcriptional repressor 0.00509523
OLFM4 olfactomedin 4 0.00509227
BMP2 bone morphogenetic protein 2 0.00508662
LYZ lysozyme 0.0050756
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.00507336
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00506261
TTN titin 0.00506172
HIC2 hypermethylated in cancer 2 0.00505995
ABHD17A abhydrolase domain containing 17A 0.00502976
DCLK1 doublecortin-like kinase 1 0.00498866
TSPYL5 TSPY-like 5 0.00496978
TMED5 transmembrane emp24 protein transport domain containing 5 0.00495812
HMG20B high mobility group 20B 0.00495147
PHACTR2 phosphatase and actin regulator 2 0.00494134
GLB1L2 galactosidase, beta 1-like 2 0.00493962
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.00493242
GLS glutaminase 0.00492864
FSTL1 follistatin-like 1 0.00492681
FHL1 four and a half LIM domains 1 0.00492043
FABP1 fatty acid binding protein 1, liver 0.00491669
ZNF217 zinc finger protein 217 0.00490793
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00490391
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00489777
ANPEP alanyl (membrane) aminopeptidase 0.00489605
HBD hemoglobin, delta 0.00489331
ADIPOR2 adiponectin receptor 2 0.00488444
TNNT1 troponin T type 1 (skeletal, slow) 0.00487973
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00487971
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00487202
PCSK6 proprotein convertase subtilisin/kexin type 6 0.00485897
ABHD6 abhydrolase domain containing 6 0.00485874
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00484897
FAR2 fatty acyl CoA reductase 2 0.00484408
MTF2 metal response element binding transcription factor 2 0.00484332
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00481276
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.00480096
COL15A1 collagen, type XV, alpha 1 0.00478022
SPARCL1 SPARC-like 1 (hevin) 0.00477226
FBLN1 fibulin 1 0.00476303
TARP TCR gamma alternate reading frame protein 0.00476118
IRAK1 interleukin-1 receptor-associated kinase 1 0.00474236
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00473645
NOTCH2 notch 2 0.00471591
NAV2 neuron navigator 2 0.00469863
TYROBP TYRO protein tyrosine kinase binding protein 0.00468856
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00468303
SEPTIN10 septin 10 0.0046805
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0046407
MCM7 minichromosome maintenance complex component 7 0.00463438
TNNI2 troponin I type 2 (skeletal, fast) 0.00462616
ASCL1 achaete-scute family bHLH transcription factor 1 0.00461318
NPY neuropeptide Y 0.00460532
REG1B regenerating islet-derived 1 beta 0.00460288
FBP1 fructose-1,6-bisphosphatase 1 0.00460241
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00459682
CLEC2B C-type lectin domain family 2, member B 0.0045934
CBS cystathionine-beta-synthase 0.00458117
PPARG peroxisome proliferator-activated receptor gamma 0.0045541
CTSG cathepsin G 0.00453952
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00453278
PDGFRL platelet-derived growth factor receptor-like 0.00452219
RAD51AP1 RAD51 associated protein 1 0.00451299
IFITM1 interferon induced transmembrane protein 1 0.00451086
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00450396
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00448744
H2AX H2A.X variant histone 0.00446938
RAP1GAP2 RAP1 GTPase activating protein 2 0.00445093
FRMD4B FERM domain containing 4B 0.00444544
CSRP2 cysteine and glycine-rich protein 2 0.00444249
EML3 echinoderm microtubule associated protein like 3 0.00444102
CCNE2 cyclin E2 0.00442425
VANGL1 VANGL planar cell polarity protein 1 0.00440366
ADGRA3 adhesion G protein-coupled receptor A3 0.00438118
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00437313
PANK3 pantothenate kinase 3 0.00436865
CD93 CD93 molecule 0.00436631
NRIP1 nuclear receptor interacting protein 1 0.00436347
PRKCZ protein kinase C, zeta 0.00435975
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.00435834
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00435311
PLXNC1 plexin C1 0.00433842
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00433609
RNPS1 RNA binding protein S1, serine-rich domain 0.00433078
ZMYND8 zinc finger, MYND-type containing 8 0.00432801
ACE2 angiotensin I converting enzyme 2 0.00432753
BEX1 brain expressed, X-linked 1 0.00432635
SOCS2 suppressor of cytokine signaling 2 0.00431919
WFDC1 WAP four-disulfide core domain 1 0.00431763
ELN elastin 0.00431426
CYTL1 cytokine-like 1 0.00430244
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00427559
SMTN smoothelin 0.00427175
LOC283683 uncharacterized LOC283683 0.0042603
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00425664
SPRY2 sprouty homolog 2 (Drosophila) 0.00425543
CTSW cathepsin W 0.00424504
XIC X chromosome inactivation center 0.00423747
TSPAN4 tetraspanin 4 0.0042331
DACH1 dachshund family transcription factor 1 0.00423151
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.00422687
RAD21 RAD21 homolog (S. pombe) 0.00421238
PLK2 polo-like kinase 2 0.00421128
EIF3B eukaryotic translation initiation factor 3, subunit B 0.00421106
SPAG1 sperm associated antigen 1 0.00420934
GALC galactosylceramidase 0.0042049
SPON2 spondin 2, extracellular matrix protein 0.00419733
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00419718
POGLUT2 protein O-glucosyltransferase 2 0.00418591
KANK2 KN motif and ankyrin repeat domains 2 0.00418545
ACTA1 actin, alpha 1, skeletal muscle 0.00416541
KLF10 Kruppel-like factor 10 0.00415678
CLDN4 claudin 4 0.00414931
RSBN1 round spermatid basic protein 1 0.00414781
PAX6 paired box 6 0.00412565
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00411767
MEN1 multiple endocrine neoplasia I 0.00411465
KAT2B K(lysine) acetyltransferase 2B 0.00409511
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.00407462
FBXO5 F-box protein 5 0.00406952
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.00406106
PKN2 protein kinase N2 0.00405984
AXIN1 axin 1 0.00405807
CGRRF1 cell growth regulator with ring finger domain 1 0.00405405
NECTIN3 nectin cell adhesion molecule 3 0.00403999
CKM creatine kinase, muscle 0.00403977
GOLGA8H golgin A8 family, member H 0.00403617
MPRIP myosin phosphatase Rho interacting protein 0.00403575
ANGPTL4 angiopoietin-like 4 0.00400693
IGF1R insulin-like growth factor 1 receptor 0.00399469
NUDCD3 NudC domain containing 3 0.0039928
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.00399064
MFAP2 microfibrillar-associated protein 2 0.00397476
IL17B interleukin 17B 0.00397007
KIF20A kinesin family member 20A 0.00396948
DAAM2 dishevelled associated activator of morphogenesis 2 0.00396644
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00395808
DBF4 DBF4 zinc finger 0.00395317
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.00394866
ADRB2 adrenoceptor beta 2, surface 0.00394812
CELF2 CUGBP, Elav-like family member 2 0.00393817
SI sucrase-isomaltase (alpha-glucosidase) 0.00393678
NOTCH2NL notch 2 N-terminal like 0.00393327
TMEM248 transmembrane protein 248 0.00393124
DAPK1 death-associated protein kinase 1 0.00392081
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00391535
SLCO4C1 solute carrier organic anion transporter family, member 4C1 0.00391143
FYN FYN proto-oncogene, Src family tyrosine kinase 0.00390975
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.00390798
SOX2 SRY (sex determining region Y)-box 2 0.00390465
SYT1 synaptotagmin I 0.00390431
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.00390037
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00389712
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00389371
PHKA2 phosphorylase kinase, alpha 2 (liver) 0.00389026
METTL9 methyltransferase like 9 0.00389007
C1ORF115 chromosome 1 open reading frame 115 0.00388869
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.00387433

decreased expression

Symbol Name Standardized Value
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00997133
EIF5A eukaryotic translation initiation factor 5A -0.00987471
POU2AF1 POU class 2 associating factor 1 -0.00922632
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00917324
HIST1H2AC histone cluster 1, H2ac -0.00889498
KRT15 keratin 15, type I -0.00878846
AQP3 aquaporin 3 (Gill blood group) -0.00876169
BAMBI BMP and activin membrane-bound inhibitor -0.00874589
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00865819
DSP desmoplakin -0.00837112
RBM34 RNA binding motif protein 34 -0.00831904
KRT7 keratin 7, type II -0.00820091
IQCG IQ motif containing G -0.0080339
LTF lactotransferrin -0.00800712
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00793496
C6ORF48 chromosome 6 open reading frame 48 -0.00791636
GPX1 glutathione peroxidase 1 -0.00777477
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.00769516
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00753285
C1QBP complement component 1, q subcomponent binding protein -0.00745804
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00731576
PPA1 pyrophosphatase (inorganic) 1 -0.00729785
HMGA1 high mobility group AT-hook 1 -0.00714295
LAMP3 lysosomal-associated membrane protein 3 -0.00707863
FTH1 ferritin, heavy polypeptide 1 -0.00693006
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00685239
VSNL1 visinin-like 1 -0.00674124
HNMT histamine N-methyltransferase -0.00659688
ISG20 interferon stimulated exonuclease gene 20kDa -0.00652387
ENAH enabled homolog (Drosophila) -0.00651962
IRS2 insulin receptor substrate 2 -0.00646044
NRN1 neuritin 1 -0.00644351
PPIF peptidylprolyl isomerase F -0.00631003
KIAA0226L KIAA0226-like -0.00624126
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00621998
KRT19 keratin 19, type I -0.00619468
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00615152
H1-2 H1.2 linker histone, cluster member -0.00612307
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00609629
DOK5 docking protein 5 -0.00607431
KRT13 keratin 13, type I -0.00606976
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00605799
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00600427
F3 coagulation factor III (thromboplastin, tissue factor) -0.0059227
ATF3 activating transcription factor 3 -0.00592032
MTARC2 mitochondrial amidoxime reducing component 2 -0.00587361
GBP2 guanylate binding protein 2, interferon-inducible -0.0058641
MMP12 matrix metallopeptidase 12 -0.00586347
PALLD palladin, cytoskeletal associated protein -0.00585863
CSTA cystatin A (stefin A) -0.00585245
TPM4 tropomyosin 4 -0.00585167
TRPS1 trichorhinophalangeal syndrome I -0.00584992
CFI complement factor I -0.00584536
MREG melanoregulin -0.00578939
BTG2 BTG family, member 2 -0.0057703
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -0.00575905
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00573188
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00572317
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00569438
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00568416
ZNF185 zinc finger protein 185 (LIM domain) -0.00565562
MVP major vault protein -0.00559636
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00558349
FABP7 fatty acid binding protein 7, brain -0.00555558
GGPS1 geranylgeranyl diphosphate synthase 1 -0.00555074
TRIM16 tripartite motif containing 16 -0.00553662
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.0055324
RAB29 RAB29, member RAS oncogene family -0.00553126
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa -0.00552802
GRB14 growth factor receptor-bound protein 14 -0.00550056
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -0.00549921
PRKCA protein kinase C, alpha -0.00549349
ZMAT3 zinc finger, matrin-type 3 -0.00548223
ANXA6 annexin A6 -0.00547734
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00545477
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00541802
FLOT1 flotillin 1 -0.00537776
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00537029
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00535436
IL1RN interleukin 1 receptor antagonist -0.00535294
GUCY2C guanylate cyclase 2C -0.00534893
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00534322
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0053169
PSAP prosaposin -0.0053159
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00526794
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00526778
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00526661
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00524807
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00524456
NEBL nebulette -0.0052249
LTBP2 latent transforming growth factor beta binding protein 2 -0.00519554
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00518714
ZYX zyxin -0.00517663
MAOB monoamine oxidase B -0.0051529
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00514689
TCTN2 tectonic family member 2 -0.00513964
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00513482
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00512953
SCGB2A2 secretoglobin, family 2A, member 2 -0.00510958
GLRX glutaredoxin (thioltransferase) -0.0050944
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00505571
SCAND1 SCAN domain containing 1 -0.00502968
NRCAM neuronal cell adhesion molecule -0.00500407
PDE4B phosphodiesterase 4B, cAMP-specific -0.00495505
FOXC1 forkhead box C1 -0.00494266
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -0.00494036
ACOX2 acyl-CoA oxidase 2, branched chain -0.00493758
MBD2 methyl-CpG binding domain protein 2 -0.00493475
FDX1 ferredoxin 1 -0.00493073
SUSD4 sushi domain containing 4 -0.0049215
PERP PERP, TP53 apoptosis effector -0.00491447
C1S complement component 1, s subcomponent -0.00490194
HOXB7 homeobox B7 -0.0048905
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -0.00488929
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00488532
PITX3 paired-like homeodomain 3 -0.00487369
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -0.00487353
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.00487221
ADSS2 adenylosuccinate synthase 2 -0.00487112
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.00485669
IPW imprinted in Prader-Willi syndrome (non-protein coding) -0.00485353
RAI14 retinoic acid induced 14 -0.0048397
CDC37L1 cell division cycle 37-like 1 -0.00483267
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 -0.00482714
LAMB3 laminin, beta 3 -0.00481922
SLPI secretory leukocyte peptidase inhibitor -0.00481407
TPM2 tropomyosin 2 (beta) -0.00481057
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00480238
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00480177
FGB fibrinogen beta chain -0.00479118
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0047849
PITX1 paired-like homeodomain 1 -0.00477663
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00476365
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00475866
BTG1 B-cell translocation gene 1, anti-proliferative -0.00474426
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00473042
FZD7 frizzled class receptor 7 -0.00472196
SELL selectin L -0.00471425
ADM adrenomedullin -0.00470113
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00468717
CP ceruloplasmin (ferroxidase) -0.00468165
TRIM22 tripartite motif containing 22 -0.00467131
TBCE tubulin folding cofactor E -0.00466317
CRIP1 cysteine-rich protein 1 (intestinal) -0.00465771
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00465479
FGG fibrinogen gamma chain -0.00465346
SCD5 stearoyl-CoA desaturase 5 -0.00464913
DAP3 death associated protein 3 -0.00461837
SMYD3 SET and MYND domain containing 3 -0.00461758
CD59 CD59 molecule, complement regulatory protein -0.00461654
BAG1 BCL2-associated athanogene -0.00461504
WNT5A wingless-type MMTV integration site family, member 5A -0.00460869
DAXX death-domain associated protein -0.00460359
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -0.00459281
SRSF6 serine/arginine-rich splicing factor 6 -0.0045888
PLAUR plasminogen activator, urokinase receptor -0.00458496
PEG3 paternally expressed 3 -0.00457782
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -0.00457406
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -0.00454767
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -0.00454296
TMPRSS4 transmembrane protease, serine 4 -0.00453508
TCL1A T-cell leukemia/lymphoma 1A -0.00452353
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00451214
HMOX1 heme oxygenase 1 -0.00450686
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -0.00450391
MOXD1 monooxygenase, DBH-like 1 -0.00450371
ZNF232 zinc finger protein 232 -0.00450136
RAB4A RAB4A, member RAS oncogene family -0.00450024
LAMC2 laminin, gamma 2 -0.00449975
FHIT fragile histidine triad -0.00449863
SCPEP1 serine carboxypeptidase 1 -0.00449156
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -0.00448666
ANXA2P2 annexin A2 pseudogene 2 -0.00447384
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00447216
CTSB cathepsin B -0.00447172
TRIB2 tribbles pseudokinase 2 -0.0044717
LITAF lipopolysaccharide-induced TNF factor -0.00446978
MZB1 marginal zone B and B1 cell-specific protein -0.00445165
LTB lymphotoxin beta (TNF superfamily, member 3) -0.0044516
RXYLT1 ribitol xylosyltransferase 1 -0.00444944
PGD phosphogluconate dehydrogenase -0.00444807
RFX5 regulatory factor X, 5 (influences HLA class II expression) -0.00444518
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00443861
FYB1 FYN binding protein 1 -0.00443162
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00443073
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -0.00441929
HIST1H2BD histone cluster 1, H2bd -0.00441188
TMEM9B TMEM9 domain family, member B -0.00441111
TM4SF4 transmembrane 4 L six family member 4 -0.00440311
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.00439247
TMEM100 transmembrane protein 100 -0.00439105
LINC00623 long intergenic non-protein coding RNA 623 -0.00436417
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -0.00436046
RIOX2 ribosomal oxygenase 2 -0.0043593
KYNU kynureninase -0.00434617
VWA8 von Willebrand factor A domain containing 8 -0.00434292
NPC2 Niemann-Pick disease, type C2 -0.00434091
RAB25 RAB25, member RAS oncogene family -0.00434051
BIK BCL2-interacting killer (apoptosis-inducing) -0.00433246
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00433032
MAMLD1 mastermind-like domain containing 1 -0.00433
RPL14 ribosomal protein L14 -0.00432466
EGR1 early growth response 1 -0.00432305
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.00431058
C1RL complement component 1, r subcomponent-like -0.00430971
SPATS2 spermatogenesis associated, serine-rich 2 -0.00430377
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A -0.00430089
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.00429636
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00429053
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00429022
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -0.00428355
CDK14 cyclin-dependent kinase 14 -0.00428032
HLA-DOB major histocompatibility complex, class II, DO beta -0.00427172
CHP1 calcineurin-like EF-hand protein 1 -0.00425252
LYPD1 LY6/PLAUR domain containing 1 -0.00424556
CLEC7A C-type lectin domain family 7, member A -0.00424067
LETMD1 LETM1 domain containing 1 -0.00423701
KRT5 keratin 5, type II -0.00422754
MRPS33 mitochondrial ribosomal protein S33 -0.00422422
GSTK1 glutathione S-transferase kappa 1 -0.00421824
PUS3 pseudouridylate synthase 3 -0.00421549
SEC14L2 SEC14-like 2 (S. cerevisiae) -0.00421227
BCL2A1 BCL2-related protein A1 -0.00420451
NLRP2 NLR family, pyrin domain containing 2 -0.00420287
F5 coagulation factor V (proaccelerin, labile factor) -0.00420049
PHF11 PHD finger protein 11 -0.00419912
S100A2 S100 calcium binding protein A2 -0.00419833
ZIC1 Zic family member 1 -0.00419448
TNC tenascin C -0.00418913
ZNF281 zinc finger protein 281 -0.0041854
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00418309
COG7 component of oligomeric golgi complex 7 -0.00417386
BST2 bone marrow stromal cell antigen 2 -0.00417314
IFI6 interferon, alpha-inducible protein 6 -0.00416515
CETN2 centrin, EF-hand protein, 2 -0.00416352
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -0.00415995
WASHC4 WASH complex subunit 4 -0.00415706
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00414851
ZNF204P zinc finger protein 204, pseudogene -0.00413813
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.00413587
SQSTM1 sequestosome 1 -0.00412989
AKR1C2 aldo-keto reductase family 1, member C2 -0.00411578
TSNAX translin-associated factor X -0.00410277
SLC16A4 solute carrier family 16, member 4 -0.00409785
HSP90B2P heat shock protein 90kDa beta (Grp94), member 2, pseudogene -0.00408627
CHI3L2 chitinase 3-like 2 -0.0040761
EIF3I eukaryotic translation initiation factor 3, subunit I -0.00407192
ACP6 acid phosphatase 6, lysophosphatidic -0.00406653
KIAA0040 KIAA0040 -0.00406281
CD52 CD52 molecule -0.00406272