TPR Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description translocated promoter region, nuclear basket protein|This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7175)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_TPR
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Genes

174 co-expressed genes for TPR from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
ARCN1 archain 1
ATG9A autophagy related 9A
ATRX alpha thalassemia/mental retardation syndrome X-linked
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
BAG1 BCL2-associated athanogene
BAHD1 bromo adjacent homology domain containing 1
BECN1 beclin 1, autophagy related
BPHL biphenyl hydrolase-like (serine hydrolase)
BRD3 bromodomain containing 3
BTD biotinidase
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CAPRIN1 cell cycle associated protein 1
CDK13 cyclin-dependent kinase 13
CDK8 cyclin-dependent kinase 8
CDYL chromodomain protein, Y-like
CETN3 centrin, EF-hand protein, 3
CHD3 chromodomain helicase DNA binding protein 3
CHD8 chromodomain helicase DNA binding protein 8
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNOT2 CCR4-NOT transcription complex, subunit 2
COPA coatomer protein complex, subunit alpha
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CSNK1D casein kinase 1, delta
CSNK1G2 casein kinase 1, gamma 2
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTAGE5 CTAGE family, member 5
CTR9 CTR9, Paf1/RNA polymerase II complex component
CUL4B cullin 4B
CYHR1 cysteine/histidine-rich 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DENND4A DENN/MADD domain containing 4A
DHPS deoxyhypusine synthase
DHRS1 dehydrogenase/reductase (SDR family) member 1
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EML3 echinoderm microtubule associated protein like 3
ERCC2 excision repair cross-complementation group 2
EXTL3 exostosin-like glycosyltransferase 3
FAF2 Fas associated factor family member 2
FAM189B family with sequence similarity 189, member B
FANCG Fanconi anemia, complementation group G
FANCI Fanconi anemia, complementation group I
FDXR ferredoxin reductase
FOXK2 forkhead box K2
FRYL FRY-like
FUS FUS RNA binding protein
GGPS1 geranylgeranyl diphosphate synthase 1
GPATCH8 G patch domain containing 8
GSK3B glycogen synthase kinase 3 beta
HTATSF1 HIV-1 Tat specific factor 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IARS isoleucyl-tRNA synthetase
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IGBP1 immunoglobulin (CD79A) binding protein 1
IK IK cytokine, down-regulator of HLA II
ILF2 interleukin enhancer binding factor 2
ILVBL ilvB (bacterial acetolactate synthase)-like
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2 interferon regulatory factor 2
JRK Jrk homolog (mouse)
KDM3B lysine (K)-specific demethylase 3B
KDM5C lysine (K)-specific demethylase 5C
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0195 KIAA0195
KIAA0586 KIAA0586
KLHDC10 kelch domain containing 10
KPNA6 karyopherin alpha 6 (importin alpha 7)
MEA1 male-enhanced antigen 1
MEN1 multiple endocrine neoplasia I
METAP1 methionyl aminopeptidase 1
MFN2 mitofusin 2
MPST mercaptopyruvate sulfurtransferase
MPV17 MpV17 mitochondrial inner membrane protein
MR1 major histocompatibility complex, class I-related
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MRPL28 mitochondrial ribosomal protein L28
MTX1 metaxin 1
MYCBP MYC binding protein
NCOA6 nuclear receptor coactivator 6
NELFB negative elongation factor complex member B
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
NFRKB nuclear factor related to kappaB binding protein
NFYB nuclear transcription factor Y, beta
NKRF NFKB repressing factor
NMT1 N-myristoyltransferase 1
NUBP1 nucleotide binding protein 1
NUP62 nucleoporin 62kDa
NUP88 nucleoporin 88kDa
OSR1 odd-skipped related transciption factor 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PARN poly(A)-specific ribonuclease
PCBP1 poly(rC) binding protein 1
PCGF1 polycomb group ring finger 1
PCGF2 polycomb group ring finger 2
PCM1 pericentriolar material 1
PDCD10 programmed cell death 10
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PHB prohibitin
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLIN3 perilipin 3
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKCSH protein kinase C substrate 80K-H
PRPF4 pre-mRNA processing factor 4
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PTGES3 prostaglandin E synthase 3 (cytosolic)
PWP1 PWP1 homolog (S. cerevisiae)
RAB11A RAB11A, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAD21 RAD21 homolog (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALB v-ral simian leukemia viral oncogene homolog B
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RING1 ring finger protein 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SEC23IP SEC23 interacting protein
SEC31A SEC31 homolog A (S. cerevisiae)
SETDB1 SET domain, bifurcated 1
SF1 splicing factor 1
SFSWAP splicing factor, suppressor of white-apricot family
SH2B1 SH2B adaptor protein 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SMAD2 SMAD family member 2
SNX4 sorting nexin 4
SP3 Sp3 transcription factor
SRRT serrate, RNA effector molecule
SS18 synovial sarcoma translocation, chromosome 18
SSR1 signal sequence receptor, alpha
STK38 serine/threonine kinase 38
STXBP3 syntaxin binding protein 3
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TBCE tubulin folding cofactor E
TBPL1 TBP-like 1
TERF2IP telomeric repeat binding factor 2, interacting protein
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM11 transmembrane protein 11
TOR1AIP1 torsin A interacting protein 1
TPR translocated promoter region, nuclear basket protein
TRA2B transformer 2 beta homolog (Drosophila)
TRIM26 tripartite motif containing 26
TSN translin
TSTA3 tissue specific transplantation antigen P35B
TTF2 transcription termination factor, RNA polymerase II
TTI1 TELO2 interacting protein 1
TTLL5 tubulin tyrosine ligase-like family member 5
TUBGCP2 tubulin, gamma complex associated protein 2
UBE2A ubiquitin-conjugating enzyme E2A
UFD1L ubiquitin fusion degradation 1 like (yeast)
WAPAL wings apart-like homolog (Drosophila)
WWOX WW domain containing oxidoreductase
XPC xeroderma pigmentosum, complementation group C
XPO6 exportin 6
ZBTB22 zinc finger and BTB domain containing 22
ZNF592 zinc finger protein 592
ZNHIT1 zinc finger, HIT-type containing 1
ZNHIT3 zinc finger, HIT-type containing 3