TPT1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description tumor protein, translationally-controlled 1| (NCBI Entrez Gene Database, 7178)
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Genes

328 genes differentially expressed following the TPT1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PRTFDC1 phosphoribosyl transferase domain containing 1 3.21026
CLEC19A C-type lectin domain family 19, member A 3.21026
WT1 Wilms tumor 1 3.21026
GJB4 gap junction protein, beta 4, 30.3kDa 3.21026
PAX6 paired box 6 3.21026
PAX5 paired box 5 3.21026
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 3.21026
LRG1 leucine-rich alpha-2-glycoprotein 1 3.21026
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 3.21026
FLII flightless I homolog (Drosophila) 3.21026
PEAR1 platelet endothelial aggregation receptor 1 3.21026
GLYAT glycine-N-acyltransferase 3.21026
HES3 hes family bHLH transcription factor 3 3.21026
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 3.21026
FAM180A family with sequence similarity 180, member A 3.21026
EGFR epidermal growth factor receptor 3.21026
SLC26A9 solute carrier family 26 (anion exchanger), member 9 3.21026
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 3.21026
PRELP proline/arginine-rich end leucine-rich repeat protein 3.21026
BTC betacellulin 3.21026
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 3.21026
HES5 hes family bHLH transcription factor 5 3.21026
VAMP8 vesicle-associated membrane protein 8 3.21026
SLC39A4 solute carrier family 39 (zinc transporter), member 4 3.21026
DIO3 deiodinase, iodothyronine, type III 3.21026
PODNL1 podocan-like 1 3.21026
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 3.21026
HIC1 hypermethylated in cancer 1 3.21026
EVPL envoplakin 3.21026
GRIFIN galectin-related inter-fiber protein 3.21026
SPAG6 sperm associated antigen 6 3.21026
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 3.21026
CCDC83 coiled-coil domain containing 83 3.21026
MISP mitotic spindle positioning 3.21026
NPIPA8 nuclear pore complex interacting protein family, member A8 3.21026
TMEM121 transmembrane protein 121 3.21026
UNC45B unc-45 homolog B (C. elegans) 3.21026
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 3.21026
POSTN periostin, osteoblast specific factor 3.21026
NOTUM notum pectinacetylesterase homolog (Drosophila) 3.21026
UBA7 ubiquitin-like modifier activating enzyme 7 3.21026
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 3.21026
CRIP1 cysteine-rich protein 1 (intestinal) 3.21026
DLL4 delta-like 4 (Drosophila) 3.21026
ADAT3 adenosine deaminase, tRNA-specific 3 3.21026
PCDHGA12 protocadherin gamma subfamily A, 12 3.21026
SPMIP10 sperm microtubule inner protein 10 3.21026
GOLGA6L7 golgin A6 family like 7 3.21026
TMOD4 tropomodulin 4 (muscle) 3.21026
MCHR1 melanin-concentrating hormone receptor 1 3.21026
AVPR1A arginine vasopressin receptor 1A 3.21026
CAPN9 calpain 9 3.21026
LRTM3 leucine rich repeat transmembrane protein 3 3.21026
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 3.21026
MGAT4D MGAT4 family, member D 3.21026
ASB9 ankyrin repeat and SOCS box containing 9 3.21026
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 3.21026
CCDC187 coiled-coil domain containing 187 3.21026
CFAP141 cilia and flagella associated protein 141 3.21026
SPMIP2 sperm microtubule inner protein 2 3.21026
FAM237A family with sequence similarity 237 member A 3.21026
ADAMTSL4-AS2 ADAMTSL4 antisense RNA 2 3.21026
NHERF4 NHERF family PDZ scaffold protein 4 3.21026
CIMAP1D CIMAP1 family member D 3.21026
TMT1B thiol methyltransferase 1B 3.21026
SPAAR small regulatory polypeptide of amino acid response 3.21026
H4C14 H4 clustered histone 14 3.21026
H2BW1 H2B.W histone 1 3.21026
DOK7 docking protein 7 3.21026
RAB36 RAB36, member RAS oncogene family 3.21026
PTPRH protein tyrosine phosphatase, receptor type, H 3.21026
IL12RB1 interleukin 12 receptor, beta 1 3.21026
FPR2 formyl peptide receptor 2 3.21026
RAET1E retinoic acid early transcript 1E 3.21026
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 3.21026
TMEM212 transmembrane protein 212 3.21026
TMPRSS11E transmembrane protease, serine 11E 3.21026
LAPTM5 lysosomal protein transmembrane 5 3.21026
CST11 cystatin 11 3.21026
TUBA3D tubulin, alpha 3d 3.21026
VSX2 visual system homeobox 2 3.21026
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 3.21026
TSPAN1 tetraspanin 1 3.21026
OR51M1 olfactory receptor, family 51, subfamily M, member 1 3.21026
GATA3 GATA binding protein 3 3.21026
MYO18B myosin XVIIIB 3.21026
STARD6 StAR-related lipid transfer (START) domain containing 6 3.21026
PGA5 pepsinogen 5, group I (pepsinogen A) 3.21026
GLIPR1L2 GLI pathogenesis-related 1 like 2 3.21026
CDSN corneodesmosin 3.21026
PRRT4 proline-rich transmembrane protein 4 3.21026
CD6 CD6 molecule 3.21026
IL23R interleukin 23 receptor 3.21026
KRT3 keratin 3, type II 3.21026
MAB21L3 mab-21-like 3 (C. elegans) 3.21026
NOX1 NADPH oxidase 1 3.21026
GOLGA6B golgin A6 family, member B 3.21026
TPSB2 tryptase beta 2 (gene/pseudogene) 3.21026
FAM177B family with sequence similarity 177, member B 3.21026
C11ORF16 chromosome 11 open reading frame 16 3.21026
HKDC1 hexokinase domain containing 1 3.21026
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 3.21026
CXCR4 chemokine (C-X-C motif) receptor 4 3.21026
C11ORF91 chromosome 11 open reading frame 91 3.21026
CCDC152 coiled-coil domain containing 152 3.21026
LRRC46 leucine rich repeat containing 46 3.21026
RGS13 regulator of G-protein signaling 13 3.21026
RGSL1 regulator of G-protein signaling like 1 3.21026
CST1 cystatin SN 3.21026
OTC ornithine carbamoyltransferase 3.21026
ADGRA1 adhesion G protein-coupled receptor A1 3.21026
S100A14 S100 calcium binding protein A14 3.21026
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 3.21026
C22ORF42 chromosome 22 open reading frame 42 3.21026
LMOD2 leiomodin 2 (cardiac) 3.21026
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 3.21026
LGALS12 lectin, galactoside-binding, soluble, 12 3.21026
CAPSL calcyphosine-like 3.21026
TSPAN19 tetraspanin 19 3.21026
CPN1 carboxypeptidase N, polypeptide 1 3.21026
CLEC18B C-type lectin domain family 18, member B 3.21026
DRC7 dynein regulatory complex subunit 7 3.21026
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.21026
PSG8 pregnancy specific beta-1-glycoprotein 8 3.21026
LHX9 LIM homeobox 9 3.21026
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 3.21026
SVOP SV2 related protein homolog (rat) 3.21026
EPHA10 EPH receptor A10 3.21026
CTXN2 cortexin 2 3.21026
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 3.21026
RBM24 RNA binding motif protein 24 3.21026
DMRT3 doublesex and mab-3 related transcription factor 3 3.21026
NCR3 natural cytotoxicity triggering receptor 3 3.21026
CFI complement factor I 3.21026
FBXO39 F-box protein 39 3.21026
NEUROD2 neuronal differentiation 2 3.21026
SOST sclerostin 3.21026
PSORS1C1 psoriasis susceptibility 1 candidate 1 3.21026
CHRM4 cholinergic receptor, muscarinic 4 3.21026
RNF222 ring finger protein 222 3.21026
LAMP3 lysosomal-associated membrane protein 3 3.21026
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 3.21026
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 3.21026
DSPP dentin sialophosphoprotein 3.21026
PRDX1 peroxiredoxin 1 3.21026
MSLN mesothelin 3.21026
LY6G5C lymphocyte antigen 6 complex, locus G5C 3.21026
PADI4 peptidyl arginine deiminase, type IV 3.21026
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 3.21026
DCST1 DC-STAMP domain containing 1 3.21026
KCTD4 potassium channel tetramerization domain containing 4 3.21026
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 3.21026
OXER1 oxoeicosanoid (OXE) receptor 1 3.21026
PLGLB2 plasminogen-like B2 3.21026
EPO erythropoietin 3.21026
LRRC32 leucine rich repeat containing 32 3.21026
STMND1 stathmin domain containing 1 3.21026
PRSS21 protease, serine, 21 (testisin) 3.21026
KIF4B kinesin family member 4B 3.21026
DHRS3 dehydrogenase/reductase (SDR family) member 3 3.21026
HRG histidine-rich glycoprotein 3.21026
CARD9 caspase recruitment domain family, member 9 3.21026
MAN1A2 mannosidase, alpha, class 1A, member 2 3.06233
SGPL1 sphingosine-1-phosphate lyase 1 3.04604
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 3.03922
GCC1 GRIP and coiled-coil domain containing 1 3.03199
PUDP pseudouridine 5'-phosphatase 2.93362
BEX3 brain expressed X-linked 3 2.93362
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 2.76132
TMEM256 transmembrane protein 256 2.74502
TRIM52 tripartite motif containing 52 2.72411
RNF152 ring finger protein 152 2.69093
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.63137
GPR39 G protein-coupled receptor 39 2.60072
AKAP11 A kinase (PRKA) anchor protein 11 2.59147
NIPSNAP2 nipsnap homolog 2 2.58764
TMEM65 transmembrane protein 65 2.58665
KASH5 KASH domain containing 5 2.57477
TMEM35A transmembrane protein 35A 2.55221
SPATA9 spermatogenesis associated 9 2.53237
CEP44 centrosomal protein 44kDa 2.53056
KCP kielin/chordin-like protein 2.48745
GRAMD1C GRAM domain containing 1C 2.4839
CFAP96 cilia and flagella associated protein 96 2.47192
ADI1 acireductone dioxygenase 1 2.38949
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.35465
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 2.3474
ZNF451 zinc finger protein 451 2.32513
MORF4L1 mortality factor 4 like 1 2.32289
C22ORF23 chromosome 22 open reading frame 23 2.3093
ERICH5 glutamate-rich 5 2.3093
OAZ3 ornithine decarboxylase antizyme 3 2.3093
C1ORF56 chromosome 1 open reading frame 56 2.30372
ARL4A ADP-ribosylation factor-like 4A 2.30372
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 2.29946
NUP93 nucleoporin 93kDa 2.17743
PGRMC1 progesterone receptor membrane component 1 2.17598
SLC25A53 solute carrier family 25, member 53 2.17251
SGO1 shugoshin 1 2.16291
HMGXB4 HMG box domain containing 4 2.16074
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 2.15973
AP3B1 adaptor-related protein complex 3, beta 1 subunit 2.15963
NNT nicotinamide nucleotide transhydrogenase 2.15941
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 2.15941
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 2.15941
TXNDC17 thioredoxin domain containing 17 2.14921
DPP9 dipeptidyl-peptidase 9 2.14876
QDPR quinoid dihydropteridine reductase 2.11938
WDR83OS WD repeat domain 83 opposite strand 2.1158
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.09468
ZMYM1 zinc finger, MYM-type 1 2.09367
SYNE2 spectrin repeat containing, nuclear envelope 2 2.0902
KLHL12 kelch-like family member 12 2.08299
ZWILCH zwilch kinetochore protein 2.07299
TMEM116 transmembrane protein 116 2.06931
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 2.06
CA4 carbonic anhydrase IV 2.05481
ANAPC7 anaphase promoting complex subunit 7 2.05304
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 2.02384
RENBP renin binding protein 2.02354
MPP1 membrane protein, palmitoylated 1, 55kDa 2.01935

decreased expression

Symbol Name Standardized Value
DKKL1 dickkopf-like 1 -3.21026
NTF4 neurotrophin 4 -3.21026
NWD2 NACHT and WD repeat domain containing 2 -3.21026
NHLH1 nescient helix loop helix 1 -3.21026
CAPN6 calpain 6 -3.21026
BBOF1 basal body orientation factor 1 -3.21026
TMEM205 transmembrane protein 205 -3.12148
IL18BP interleukin 18 binding protein -2.95818
TBCD tubulin folding cofactor D -2.95768
SYNPO2L synaptopodin 2-like -2.93362
TMEM86B transmembrane protein 86B -2.93362
MYD88 myeloid differentiation primary response 88 -2.93362
ADGB androglobin -2.93362
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 -2.93362
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -2.93362
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -2.93362
CHAD chondroadherin -2.93362
AKAP14 A kinase (PRKA) anchor protein 14 -2.93362
NAPSA napsin A aspartic peptidase -2.93362
JOSD2 Josephin domain containing 2 -2.93362
PVALEF parvalbumin like EF-hand containing -2.93362
CCER2 coiled-coil glutamate-rich protein 2 -2.93362
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -2.93362
HSH2D hematopoietic SH2 domain containing -2.93362
ACE2 angiotensin I converting enzyme 2 -2.93362
PCDHGC3 protocadherin gamma subfamily C, 3 -2.93362
LGSN lengsin, lens protein with glutamine synthetase domain -2.93362
CCR6 chemokine (C-C motif) receptor 6 -2.93362
PRB4 proline-rich protein BstNI subfamily 4 -2.93362
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -2.93362
GJA9 gap junction protein, alpha 9, 59kDa -2.93362
HRH4 histamine receptor H4 -2.93362
TLCD2 TLC domain containing 2 -2.93362
ACSS1 acyl-CoA synthetase short-chain family member 1 -2.93362
EDN1 endothelin 1 -2.93362
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -2.93362
CALR3 calreticulin 3 -2.93362
LOXHD1 lipoxygenase homology domains 1 -2.93362
AMN amnion associated transmembrane protein -2.93362
CCDC78 coiled-coil domain containing 78 -2.93362
ECE2 endothelin converting enzyme 2 -2.93362
ADRA2A adrenoceptor alpha 2A -2.93362
SYNM synemin, intermediate filament protein -2.81952
GEM GTP binding protein overexpressed in skeletal muscle -2.7449
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 -2.7449
LIMS2 LIM and senescent cell antigen-like domains 2 -2.7449
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -2.72048
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) -2.70766
KIF21A kinesin family member 21A -2.70452
ODAD2 outer dynein arm docking complex subunit 2 -2.70068
GIGYF2 GRB10 interacting GYF protein 2 -2.67381
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 -2.64402
FXR2 fragile X mental retardation, autosomal homolog 2 -2.57964
ARMCX3 armadillo repeat containing, X-linked 3 -2.57477
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.57266
DTX4 deltex 4, E3 ubiquitin ligase -2.56513
INSL6 insulin-like 6 -2.55192
SAP25 Sin3A-associated protein, 25kDa -2.55192
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.53237
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 -2.49338
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) -2.48745
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -2.48733
NPY5R neuropeptide Y receptor Y5 -2.47748
CDK9 cyclin-dependent kinase 9 -2.46315
NUP58 nucleoporin 58 -2.46275
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 -2.40424
ZNF70 zinc finger protein 70 -2.40424
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -2.39039
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.34451
USP54 ubiquitin specific peptidase 54 -2.31988
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -2.30399
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) -2.30399
MYO9B myosin IXB -2.29472
GNMT glycine N-methyltransferase -2.27147
NLRC4 NLR family, CARD domain containing 4 -2.27147
NINL ninein-like -2.25948
TRIM4 tripartite motif containing 4 -2.25142
CDC16 cell division cycle 16 -2.25142
ZNF232 zinc finger protein 232 -2.24436
TPT1 tumor protein, translationally-controlled 1 -2.22903
SRPK2 SRSF protein kinase 2 -2.2045
HOMEZ homeobox and leucine zipper encoding -2.19845
PPP1R36 protein phosphatase 1, regulatory subunit 36 -2.1841
DPP8 dipeptidyl-peptidase 8 -2.17354
KCTD19 potassium channel tetramerization domain containing 19 -2.16521
MCMBP minichromosome maintenance complex binding protein -2.1445
SMAD5 SMAD family member 5 -2.12738
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.12738
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -2.12388
SYT12 synaptotagmin XII -2.11626
TOMM34 translocase of outer mitochondrial membrane 34 -2.1158
H4C8 H4 clustered histone 8 -2.10892
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.09468
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 -2.09367
NOS3 nitric oxide synthase 3 (endothelial cell) -2.0902
ZBTB20 zinc finger and BTB domain containing 20 -2.0902
MAPK9 mitogen-activated protein kinase 9 -2.0902
NUTM1 NUT midline carcinoma, family member 1 -2.08861
MAP1A microtubule-associated protein 1A -2.08861
CCNQ cyclin Q -2.07179
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.06
UTF1 undifferentiated embryonic cell transcription factor 1 -2.05481
IQCE IQ motif containing E -2.04981
ZCCHC8 zinc finger, CCHC domain containing 8 -2.0413
GTF2H2C GTF2H2 family member C -2.03016
CENATAC centrosomal AT-AC splicing factor -2.01381
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 -2.00249