TR4 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description nuclear receptor subfamily 2, group C, member 2|This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 7182)
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Genes

48 target genes of the TR4 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ADPGK-AS1 ADPGK antisense RNA 1
ALPI alkaline phosphatase, intestinal
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARID4B AT rich interactive domain 4B (RBP1-like)
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CRYM-AS1 CRYM antisense RNA 1
DBP D site of albumin promoter (albumin D-box) binding protein
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
EYA4 EYA transcriptional coactivator and phosphatase 4
GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene
GPR158 G protein-coupled receptor 158
HLA-DMA major histocompatibility complex, class II, DM alpha
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB6 integrin, beta 6
KDM6A lysine (K)-specific demethylase 6A
L1CAM L1 cell adhesion molecule
MDK midkine (neurite growth-promoting factor 2)
MIR921 microRNA 921
MMP11 matrix metallopeptidase 11
MPI mannose phosphate isomerase
MTCP1 mature T-cell proliferation 1
MYF5 myogenic factor 5
MYO1C myosin IC
NAV2 neuron navigator 2
NDE1 nudE neurodevelopment protein 1
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NNAT neuronatin
NOP2 NOP2 nucleolar protein
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRPH peripherin
RARG retinoic acid receptor, gamma
RPS3A ribosomal protein S3A
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SPEN spen family transcriptional repressor
STRIP2 striatin interacting protein 2
TBC1D22A TBC1 domain family, member 22A
TMEM125 transmembrane protein 125
TSPAN7 tetraspanin 7
XKR7 XK, Kell blood group complex subunit-related family, member 7
XPR1 xenotropic and polytropic retrovirus receptor 1
YPEL3 yippee-like 3 (Drosophila)
ZMYM4 zinc finger, MYM-type 4
ZNF503-AS2 ZNF503 antisense RNA 2