| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | TNF receptor-associated factor 2|The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7186) |
| External Link | https://ncbi.nlm.nih.gov/gene/7186 |
| Similar Terms | |
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496 genes differentially expressed following the TRAF2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.0196201 |
| GLOD4 | glyoxalase domain containing 4 | 0.0175591 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.0152136 |
| SIRT3 | sirtuin 3 | 0.0147576 |
| LTF | lactotransferrin | 0.0142553 |
| CA2 | carbonic anhydrase II | 0.0140392 |
| H1-0 | H1.0 linker histone | 0.0136903 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.0127983 |
| HNMT | histamine N-methyltransferase | 0.0122981 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0122732 |
| MYBPC1 | myosin binding protein C, slow type | 0.0120333 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0116075 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0112086 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0109188 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.010881 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0108717 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0108419 |
| GLUL | glutamate-ammonia ligase | 0.0102286 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.0100607 |
| PRDX3 | peroxiredoxin 3 | 0.00991955 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00987841 |
| CD200 | CD200 molecule | 0.009799 |
| GLUD1 | glutamate dehydrogenase 1 | 0.0097147 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00960666 |
| MB | myoglobin | 0.00956217 |
| MAT2B | methionine adenosyltransferase II, beta | 0.00954035 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.0094493 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00919398 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.0091151 |
| DAZAP2 | DAZ associated protein 2 | 0.00908031 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00907146 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00906684 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00903101 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00900333 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00896937 |
| GLUD2 | glutamate dehydrogenase 2 | 0.00888807 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0088332 |
| PLEK | pleckstrin | 0.00882258 |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.00874628 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00870917 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00863712 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00862889 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00862301 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00858989 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00853569 |
| CNN3 | calponin 3, acidic | 0.00842571 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00842399 |
| NTS | neurotensin | 0.00841322 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00834499 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 | 0.00833351 |
| CDK14 | cyclin-dependent kinase 14 | 0.0082838 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00827428 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.00827134 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00826494 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00825523 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 | 0.0082282 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00819345 |
| COMMD10 | COMM domain containing 10 | 0.00812947 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00805898 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00798533 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00798343 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00795742 |
| ILK | integrin-linked kinase | 0.00790435 |
| CLDND1 | claudin domain containing 1 | 0.0078552 |
| CYBRD1 | cytochrome b reductase 1 | 0.00784297 |
| GOLM1 | golgi membrane protein 1 | 0.00781804 |
| CCNA2 | cyclin A2 | 0.00774086 |
| NES | nestin | 0.0077319 |
| KIFAP3 | kinesin-associated protein 3 | 0.00772583 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00769032 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00768583 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.0076495 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00764655 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00760963 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00760801 |
| CHEK2 | checkpoint kinase 2 | 0.00760262 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00754833 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.0074813 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00741542 |
| SLN | sarcolipin | 0.00738735 |
| PFDN5 | prefoldin subunit 5 | 0.00736319 |
| TARP | TCR gamma alternate reading frame protein | 0.00735541 |
| TMEM38B | transmembrane protein 38B | 0.00735088 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00732039 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00731917 |
| CD52 | CD52 molecule | 0.00727414 |
| MRPL24 | mitochondrial ribosomal protein L24 | 0.00727359 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | 0.00725903 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00724894 |
| HBD | hemoglobin, delta | 0.00722611 |
| TMEM14B | transmembrane protein 14B | 0.00721999 |
| APOC2 | apolipoprotein C-II | 0.00721669 |
| TNC | tenascin C | 0.00718994 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00718867 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00716004 |
| POLB | polymerase (DNA directed), beta | 0.00713016 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.0071004 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00702906 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00701066 |
| KRT23 | keratin 23, type I | 0.00700938 |
| NEK2 | NIMA-related kinase 2 | 0.00699889 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00698612 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00689447 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00687697 |
| MMP12 | matrix metallopeptidase 12 | 0.00687692 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00681972 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0068016 |
| C11ORF58 | chromosome 11 open reading frame 58 | 0.00680118 |
| LYZ | lysozyme | 0.00678535 |
| NEK7 | NIMA-related kinase 7 | 0.0067799 |
| PER3 | period circadian clock 3 | 0.00677699 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00677628 |
| A2M | alpha-2-macroglobulin | 0.00676469 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00674598 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00672464 |
| THYN1 | thymocyte nuclear protein 1 | 0.00671983 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00668914 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00667607 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00665669 |
| NIPSNAP2 | nipsnap homolog 2 | 0.00664667 |
| IL1RN | interleukin 1 receptor antagonist | 0.00662383 |
| HAX1 | HCLS1 associated protein X-1 | 0.00661603 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00660091 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00659088 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.0065582 |
| COPS4 | COP9 signalosome subunit 4 | 0.00655247 |
| GRAMD1C | GRAM domain containing 1C | 0.00655056 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0065289 |
| PRKCA | protein kinase C, alpha | 0.00650418 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.0065014 |
| MED28 | mediator complex subunit 28 | 0.00649964 |
| ALB | albumin | 0.00649826 |
| MME | membrane metallo-endopeptidase | 0.00648536 |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 | 0.00648382 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00648059 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | 0.00646034 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.00645481 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00644418 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.00640405 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 0.00640375 |
| EAPP | E2F-associated phosphoprotein | 0.0063698 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.00633958 |
| THY1 | Thy-1 cell surface antigen | 0.00631955 |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) | 0.00631457 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00628056 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00625581 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00623586 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0062265 |
| FMO5 | flavin containing monooxygenase 5 | 0.0062175 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | 0.00620634 |
| HMGB2 | high mobility group box 2 | 0.00620236 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.00619696 |
| DOK5 | docking protein 5 | 0.00619681 |
| NCOA4 | nuclear receptor coactivator 4 | 0.00618242 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.00618087 |
| SRP9 | signal recognition particle 9kDa | 0.0061359 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00613263 |
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 | 0.00612598 |
| EXTL2 | exostosin-like glycosyltransferase 2 | 0.00611706 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00611471 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | 0.0061121 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00609845 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.0060542 |
| PEX11B | peroxisomal biogenesis factor 11 beta | 0.00604485 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00603823 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00603015 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00602857 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00602253 |
| BCL2A1 | BCL2-related protein A1 | 0.00602187 |
| RPS17 | ribosomal protein S17 | 0.0059926 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00599167 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00599062 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00598239 |
| MYOT | myotilin | 0.00597002 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.00596612 |
| RBMX | RNA binding motif protein, X-linked | 0.00596208 |
| NUP37 | nucleoporin 37kDa | 0.00596076 |
| CALML3 | calmodulin-like 3 | 0.00595921 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00591776 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00591336 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00591181 |
| RHOA | ras homolog family member A | 0.00587644 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | 0.00586849 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.00586192 |
| FN3KRP | fructosamine 3 kinase related protein | 0.00585689 |
| RPS5 | ribosomal protein S5 | 0.00585668 |
| MREG | melanoregulin | 0.00585093 |
| RAB13 | RAB13, member RAS oncogene family | 0.00584982 |
| ACP3 | acid phosphatase 3 | 0.00584385 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | 0.0058325 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.00583158 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00581418 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00581354 |
| CDCA4 | cell division cycle associated 4 | 0.00581287 |
| SELL | selectin L | 0.00581099 |
| CANX | calnexin | 0.00580845 |
| WDR61 | WD repeat domain 61 | 0.00580769 |
| RAD51C | RAD51 paralog C | 0.00580176 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00579199 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | 0.00578162 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 0.00577517 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | 0.005775 |
| IL15 | interleukin 15 | 0.00577441 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00577242 |
| HPX | hemopexin | 0.00576344 |
| PGD | phosphogluconate dehydrogenase | 0.00576304 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00575751 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00575305 |
| GJB1 | gap junction protein, beta 1, 32kDa | 0.00574708 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 | 0.00574325 |
| ERGIC2 | ERGIC and golgi 2 | 0.00574052 |
| CPOX | coproporphyrinogen oxidase | 0.00573203 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.00572953 |
| ATG5 | autophagy related 5 | 0.00571539 |
| MYO1C | myosin IC | 0.00570949 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0057076 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | 0.00570679 |
| SUSD4 | sushi domain containing 4 | 0.00570528 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.00570378 |
| PEX2 | peroxisomal biogenesis factor 2 | 0.00569713 |
| DAP | death-associated protein | 0.00569355 |
| STOML2 | stomatin (EPB72)-like 2 | 0.00568765 |
| HAL | histidine ammonia-lyase | 0.00568553 |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.00568389 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00567926 |
| PCYOX1L | prenylcysteine oxidase 1 like | 0.00567911 |
| CCL17 | chemokine (C-C motif) ligand 17 | 0.00566933 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.0056678 |
| TERF2 | telomeric repeat binding factor 2 | 0.00566522 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00565855 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00564773 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | 0.00564297 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00564198 |
| MYOZ1 | myozenin 1 | 0.00563917 |
| TTN | titin | 0.00563401 |
| DHPS | deoxyhypusine synthase | 0.00562605 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 0.00560322 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00557879 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.0055764 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00555747 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00553619 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00553164 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.00551953 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00551839 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00551428 |
| SET | SET nuclear proto-oncogene | 0.00550958 |
| ANO10 | anoctamin 10 | 0.005507 |
| FGG | fibrinogen gamma chain | 0.0055014 |
| CD69 | CD69 molecule | 0.0055002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTK2 | protein tyrosine kinase 2 | -0.0156181 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0140949 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0139175 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.0139087 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0138516 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0132557 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.0129299 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0129072 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0127676 |
| AEBP1 | AE binding protein 1 | -0.0125384 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0118479 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0116668 |
| LAMB1 | laminin, beta 1 | -0.011153 |
| BRD2 | bromodomain containing 2 | -0.0111067 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0110749 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0108142 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.010712 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0106347 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0106225 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.0104301 |
| ACKR3 | atypical chemokine receptor 3 | -0.0103085 |
| APOD | apolipoprotein D | -0.0102254 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0102168 |
| SIK1 | salt-inducible kinase 1 | -0.0101113 |
| PNMA8A | PNMA family member 8A | -0.010003 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00983239 |
| STC1 | stanniocalcin 1 | -0.00977849 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00977787 |
| NDRG1 | N-myc downstream regulated 1 | -0.009627 |
| ZNF423 | zinc finger protein 423 | -0.00959321 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00947658 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0094571 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00940179 |
| CFD | complement factor D (adipsin) | -0.00938777 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00936764 |
| TUFT1 | tuftelin 1 | -0.00934206 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00930174 |
| NVL | nuclear VCP-like | -0.00925539 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00918764 |
| NRCAM | neuronal cell adhesion molecule | -0.0091858 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.0091827 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00910827 |
| SYNGR3 | synaptogyrin 3 | -0.0090992 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.008925 |
| NOTCH2NL | notch 2 N-terminal like | -0.00891631 |
| PROCR | protein C receptor, endothelial | -0.0088654 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00881522 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00880923 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00879301 |
| FN1 | fibronectin 1 | -0.00868304 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00860036 |
| AXL | AXL receptor tyrosine kinase | -0.00852984 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00850278 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.00850054 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00846499 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00841569 |
| PROM1 | prominin 1 | -0.00839974 |
| SMAD7 | SMAD family member 7 | -0.0083772 |
| GPX3 | glutathione peroxidase 3 | -0.00832968 |
| ANGPTL4 | angiopoietin-like 4 | -0.00832832 |
| MID1 | midline 1 | -0.00832549 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0082891 |
| HMOX1 | heme oxygenase 1 | -0.00827988 |
| PMP22 | peripheral myelin protein 22 | -0.0082557 |
| GOLGA8H | golgin A8 family, member H | -0.00823099 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00822226 |
| AMOTL2 | angiomotin like 2 | -0.00820996 |
| LIPG | lipase, endothelial | -0.00816913 |
| CRY1 | cryptochrome circadian clock 1 | -0.00816353 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00815321 |
| LAMA2 | laminin, alpha 2 | -0.00809706 |
| MIR22HG | MIR22 host gene | -0.00808154 |
| NPTX2 | neuronal pentraxin II | -0.00807442 |
| IPO13 | importin 13 | -0.00806424 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00801938 |
| FBLN2 | fibulin 2 | -0.0079848 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00797349 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0079717 |
| MYO1B | myosin IB | -0.00797116 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00790412 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00788818 |
| DCLK1 | doublecortin-like kinase 1 | -0.00788395 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00787577 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00786011 |
| LAMA5 | laminin, alpha 5 | -0.00783436 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00782914 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00782498 |
| AGR2 | anterior gradient 2 | -0.00781901 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00775332 |
| PXDC1 | PX domain containing 1 | -0.00774165 |
| THBS4 | thrombospondin 4 | -0.00773748 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00773173 |
| MYO6 | myosin VI | -0.00769028 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00769025 |
| EZR | ezrin | -0.00765356 |
| AKIRIN1 | akirin 1 | -0.00765051 |
| PLK2 | polo-like kinase 2 | -0.00761397 |
| MMP3 | matrix metallopeptidase 3 | -0.00759502 |
| RGS5 | regulator of G-protein signaling 5 | -0.00758507 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00758001 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00755502 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00752769 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00752423 |
| SPP1 | secreted phosphoprotein 1 | -0.00748431 |
| S100P | S100 calcium binding protein P | -0.00744708 |
| TAC1 | tachykinin, precursor 1 | -0.00744022 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00742845 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.0074041 |
| LOXL2 | lysyl oxidase-like 2 | -0.00738922 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00737167 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0073663 |
| SPATA20 | spermatogenesis associated 20 | -0.00734347 |
| EFNA1 | ephrin-A1 | -0.00729395 |
| ASPN | asporin | -0.00729214 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00729035 |
| CCND3 | cyclin D3 | -0.00727938 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00725893 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.00724449 |
| S100A11 | S100 calcium binding protein A11 | -0.00723423 |
| TSPAN13 | tetraspanin 13 | -0.00722662 |
| MAP7 | microtubule-associated protein 7 | -0.00721515 |
| TGFA | transforming growth factor, alpha | -0.00721285 |
| COMP | cartilage oligomeric matrix protein | -0.00720254 |
| FOXJ3 | forkhead box J3 | -0.00717737 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.00712367 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00712212 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00712131 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00711673 |
| FBLN1 | fibulin 1 | -0.00711313 |
| RHOB | ras homolog family member B | -0.00709789 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0070969 |
| H1-2 | H1.2 linker histone, cluster member | -0.00708942 |
| DACH1 | dachshund family transcription factor 1 | -0.00708413 |
| IRF7 | interferon regulatory factor 7 | -0.00708372 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.00706879 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00705898 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00705555 |
| GNAS | GNAS complex locus | -0.00698802 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00697386 |
| MINK1 | misshapen-like kinase 1 | -0.00696962 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0069608 |
| CTSL | cathepsin L | -0.00694261 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00692294 |
| LEFTY1 | left-right determination factor 1 | -0.00690699 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00689994 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00689287 |
| PLS3 | plastin 3 | -0.00688535 |
| HK2 | hexokinase 2 | -0.00687208 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00685142 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00682563 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.00682363 |
| TUBB6 | tubulin, beta 6 class V | -0.00679676 |
| S100A8 | S100 calcium binding protein A8 | -0.00679248 |
| ADCY9 | adenylate cyclase 9 | -0.00677693 |
| ATP9A | ATPase, class II, type 9A | -0.0067653 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00675982 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00675862 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.0067498 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00673538 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.00671246 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00670432 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0066952 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00668748 |
| G0S2 | G0/G1 switch 2 | -0.00665136 |
| CUX1 | cut-like homeobox 1 | -0.00663962 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.00663592 |
| CERT1 | ceramide transporter 1 | -0.00661388 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00660975 |
| TMEM260 | transmembrane protein 260 | -0.00660332 |
| COL1A1 | collagen, type I, alpha 1 | -0.00659585 |
| PRKCZ | protein kinase C, zeta | -0.00658469 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00657015 |
| LCN2 | lipocalin 2 | -0.00656907 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00656611 |
| JMJD1C | jumonji domain containing 1C | -0.00652763 |
| RBPMS | RNA binding protein with multiple splicing | -0.00651393 |
| NID2 | nidogen 2 (osteonidogen) | -0.00650985 |
| SAFB2 | scaffold attachment factor B2 | -0.00650614 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00650413 |
| GALC | galactosylceramidase | -0.0065029 |
| FAM13A | family with sequence similarity 13, member A | -0.00649778 |
| IL6 | interleukin 6 | -0.00649353 |
| MSN | moesin | -0.00647784 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00647583 |
| IGF2R | insulin-like growth factor 2 receptor | -0.00645896 |
| ZNF12 | zinc finger protein 12 | -0.00643688 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00642631 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.0064255 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00641173 |
| STAG2 | stromal antigen 2 | -0.00639725 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.00637017 |
| NKX2-1 | NK2 homeobox 1 | -0.0063696 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.00636735 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00636221 |
| INAVA | innate immunity activator | -0.00631738 |
| JAG1 | jagged 1 | -0.00630877 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00628923 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00628114 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.00627896 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | -0.00627777 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00627148 |
| CLCN4 | chloride channel, voltage-sensitive 4 | -0.00626598 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00626596 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.00626407 |
| TXLNA | taxilin alpha | -0.00626157 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00625623 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.00624866 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00623529 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00622531 |
| PRRC2C | proline-rich coiled-coil 2C | -0.00618775 |
| VLDLR | very low density lipoprotein receptor | -0.00618663 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00618246 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00617978 |
| ATP13A1 | ATPase type 13A1 | -0.00617541 |
| ING3 | inhibitor of growth family, member 3 | -0.00617008 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00616323 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00615857 |
| EGR1 | early growth response 1 | -0.00615443 |
| AGRN | agrin | -0.00615075 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0061457 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00614013 |
| KIAA0930 | KIAA0930 | -0.00613928 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00611281 |
| SYT1 | synaptotagmin I | -0.00611186 |
| FZD2 | frizzled class receptor 2 | -0.00611061 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00610867 |
| STK39 | serine threonine kinase 39 | -0.00610396 |
| MYLIP | myosin regulatory light chain interacting protein | -0.00610345 |
| PDZD2 | PDZ domain containing 2 | -0.0060764 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00606339 |
| PLXNA1 | plexin A1 | -0.00605512 |
| FRZB | frizzled-related protein | -0.00604889 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.00604842 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00604032 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0060389 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00603799 |
| TPD52 | tumor protein D52 | -0.00603797 |
| FOXD1 | forkhead box D1 | -0.00603146 |
| CTSK | cathepsin K | -0.00602872 |
| SQSTM1 | sequestosome 1 | -0.00601376 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00600369 |
| NOTCH1 | notch 1 | -0.005996 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00599569 |
| MXRA5 | matrix-remodelling associated 5 | -0.00598466 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00596426 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00596406 |
| SDCBP | syndecan binding protein (syntenin) | -0.0059612 |
