| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | TNF receptor-associated factor 3|The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 7187) |
| External Link | https://ncbi.nlm.nih.gov/gene/7187 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the TRAF3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT14 | keratin 14, type I | 0.0147583 |
| PTK2 | protein tyrosine kinase 2 | 0.0146932 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0137723 |
| KRT6A | keratin 6A, type II | 0.0118279 |
| CD9 | CD9 molecule | 0.0118084 |
| S100A7 | S100 calcium binding protein A7 | 0.0115245 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0113482 |
| CSTA | cystatin A (stefin A) | 0.0109893 |
| KRT16 | keratin 16, type I | 0.01041 |
| SPRR2B | small proline-rich protein 2B | 0.0101586 |
| KRT5 | keratin 5, type II | 0.0100944 |
| SIRT3 | sirtuin 3 | 0.0100574 |
| S100A10 | S100 calcium binding protein A10 | 0.0100169 |
| CA12 | carbonic anhydrase XII | 0.00993728 |
| KRT13 | keratin 13, type I | 0.00973568 |
| S100A2 | S100 calcium binding protein A2 | 0.0096682 |
| SYNGR3 | synaptogyrin 3 | 0.00956593 |
| SPRR1A | small proline-rich protein 1A | 0.00955988 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00929302 |
| KRT6B | keratin 6B, type II | 0.00927448 |
| PLS3 | plastin 3 | 0.00926054 |
| S100A9 | S100 calcium binding protein A9 | 0.00914487 |
| AREG | amphiregulin | 0.00909472 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00904397 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00895811 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00894257 |
| HTRA1 | HtrA serine peptidase 1 | 0.00892083 |
| SPRR1B | small proline-rich protein 1B | 0.00885696 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00881553 |
| MMP9 | matrix metallopeptidase 9 | 0.00879944 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00876071 |
| STC2 | stanniocalcin 2 | 0.00871917 |
| SFN | stratifin | 0.00867431 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00857866 |
| KRT17 | keratin 17, type I | 0.00854771 |
| RHCG | Rh family, C glycoprotein | 0.00833376 |
| CHI3L2 | chitinase 3-like 2 | 0.00814268 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00810276 |
| RGS4 | regulator of G-protein signaling 4 | 0.00801738 |
| TMEM14A | transmembrane protein 14A | 0.0080134 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00797723 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00793068 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.00790877 |
| RCAN1 | regulator of calcineurin 1 | 0.00787775 |
| CST7 | cystatin F (leukocystatin) | 0.00787284 |
| CHEK2 | checkpoint kinase 2 | 0.00784461 |
| TRIM29 | tripartite motif containing 29 | 0.00784394 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00766043 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00764351 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00762574 |
| PTGES | prostaglandin E synthase | 0.00758829 |
| RBM34 | RNA binding motif protein 34 | 0.00753527 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00743832 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00742882 |
| FOXD1 | forkhead box D1 | 0.00735693 |
| COL5A2 | collagen, type V, alpha 2 | 0.00734479 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0073258 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00729231 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00728323 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.00720888 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.00718397 |
| SPRR3 | small proline-rich protein 3 | 0.00716099 |
| CD27 | CD27 molecule | 0.00710041 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00708275 |
| KRT15 | keratin 15, type I | 0.00706929 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00703607 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0070266 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00702185 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.00696668 |
| ADM | adrenomedullin | 0.00688689 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00679706 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0067037 |
| EREG | epiregulin | 0.00669884 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.0066924 |
| DSP | desmoplakin | 0.00664501 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00663375 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00663157 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00660793 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00659344 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.00657675 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00655538 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00651638 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00651004 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00650852 |
| CST3 | cystatin C | 0.00648463 |
| EMP3 | epithelial membrane protein 3 | 0.0064477 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00644315 |
| ITGAV | integrin, alpha V | 0.0064326 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00640932 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00638989 |
| STK17A | serine/threonine kinase 17a | 0.00638712 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00638436 |
| ANXA1 | annexin A1 | 0.00638195 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00634932 |
| CNN2 | calponin 2 | 0.00634915 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00633449 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00632312 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00629487 |
| IL2RG | interleukin 2 receptor, gamma | 0.00628047 |
| SIK1 | salt-inducible kinase 1 | 0.00625869 |
| IFT20 | intraflagellar transport 20 | 0.00625462 |
| JAG1 | jagged 1 | 0.00625034 |
| MARCKSL1 | MARCKS-like 1 | 0.00624914 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00619907 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00618347 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00614561 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00613116 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00611326 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00610516 |
| JUP | junction plakoglobin | 0.00609605 |
| HOXC10 | homeobox C10 | 0.00609309 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00605898 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00604348 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 0.00602415 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00601844 |
| GLTP | glycolipid transfer protein | 0.00600484 |
| TSPO | translocator protein (18kDa) | 0.00590969 |
| COCH | cochlin | 0.00589904 |
| UPK1B | uroplakin 1B | 0.00585562 |
| OFD1 | oral-facial-digital syndrome 1 | 0.00582926 |
| FOXC1 | forkhead box C1 | 0.00581153 |
| PDCD10 | programmed cell death 10 | 0.00575347 |
| COMMD3 | COMM domain containing 3 | 0.00574397 |
| IQCG | IQ motif containing G | 0.00574077 |
| DSG3 | desmoglein 3 | 0.00573583 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00573575 |
| CLU | clusterin | 0.00570682 |
| CHPT1 | choline phosphotransferase 1 | 0.00569992 |
| CTSD | cathepsin D | 0.00566199 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.00563999 |
| MLF1 | myeloid leukemia factor 1 | 0.00561388 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00559878 |
| NDRG1 | N-myc downstream regulated 1 | 0.00558183 |
| PITX3 | paired-like homeodomain 3 | 0.00556282 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00555703 |
| IL32 | interleukin 32 | 0.00555557 |
| TOB1 | transducer of ERBB2, 1 | 0.00555048 |
| PSPH | phosphoserine phosphatase | 0.00554216 |
| C1S | complement component 1, s subcomponent | 0.0055287 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00552727 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00552457 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.00550693 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | 0.00546458 |
| AIM2 | absent in melanoma 2 | 0.0054501 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | 0.00542518 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00541353 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00540248 |
| RFK | riboflavin kinase | 0.00537913 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.0053533 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.00533872 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00533084 |
| PKM | pyruvate kinase, muscle | 0.00530346 |
| LYRM4 | LYR motif containing 4 | 0.00527896 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00527857 |
| ANXA2 | annexin A2 | 0.00526195 |
| TWF1 | twinfilin actin binding protein 1 | 0.0052491 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00520114 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00516791 |
| RPS5 | ribosomal protein S5 | 0.0051663 |
| GOLT1B | golgi transport 1B | 0.0051512 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00515073 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.00512099 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.00511723 |
| PKP1 | plakophilin 1 | 0.00508264 |
| NUTF2 | nuclear transport factor 2 | 0.00507466 |
| NOSIP | nitric oxide synthase interacting protein | 0.0050703 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00505981 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.0050571 |
| MXRA7 | matrix-remodelling associated 7 | 0.00505356 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00504731 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00504308 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00501742 |
| MAL | mal, T-cell differentiation protein | 0.00501196 |
| IL18 | interleukin 18 | 0.00500017 |
| CLIC3 | chloride intracellular channel 3 | 0.00499815 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00499437 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00497642 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.004921 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00490868 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00489753 |
| TMEM41B | transmembrane protein 41B | 0.00488737 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00486818 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00486681 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00483168 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00482579 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00481379 |
| HDDC2 | HD domain containing 2 | 0.00480681 |
| IL2RB | interleukin 2 receptor, beta | 0.00480665 |
| SMOX | spermine oxidase | 0.00479294 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00479123 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00479069 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 0.00478689 |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | 0.00477109 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00475774 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00475269 |
| NOTCH3 | notch 3 | 0.00474896 |
| MPC2 | mitochondrial pyruvate carrier 2 | 0.00474719 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00473967 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00473878 |
| GPX2 | glutathione peroxidase 2 | 0.00473229 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00473132 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00472839 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00472655 |
| SMS | spermine synthase | 0.00472264 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00470413 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.0047023 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0046889 |
| NNMT | nicotinamide N-methyltransferase | 0.00468846 |
| ADD2 | adducin 2 (beta) | 0.00468027 |
| PMP2 | peripheral myelin protein 2 | 0.00466736 |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.00466611 |
| CD2 | CD2 molecule | 0.00466238 |
| ANO3 | anoctamin 3 | 0.00465441 |
| CRIPT | cysteine-rich PDZ-binding protein | 0.00465391 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.00465308 |
| PRKCI | protein kinase C, iota | 0.00464715 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00464675 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.00463494 |
| ADD3 | adducin 3 (gamma) | 0.00463357 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.00463324 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0045958 |
| TCL1B | T-cell leukemia/lymphoma 1B | 0.00458948 |
| H1-2 | H1.2 linker histone, cluster member | 0.00457773 |
| TMEM9B | TMEM9 domain family, member B | 0.00456661 |
| SFXN1 | sideroflexin 1 | 0.00456204 |
| CD58 | CD58 molecule | 0.00456125 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.00456028 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.00455366 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) | 0.00454291 |
| IER3IP1 | immediate early response 3 interacting protein 1 | 0.00454016 |
| MICB | MHC class I polypeptide-related sequence B | 0.00452691 |
| LRRC17 | leucine rich repeat containing 17 | 0.00451705 |
| KRT10 | keratin 10, type I | 0.00451047 |
| CCNB1 | cyclin B1 | 0.00448529 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 | 0.00448459 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00447707 |
| CD19 | CD19 molecule | 0.00447288 |
| IL7R | interleukin 7 receptor | 0.00447192 |
| DEFB4A | defensin, beta 4A | 0.00444712 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00443521 |
| SATB2 | SATB homeobox 2 | 0.00441733 |
| CNN3 | calponin 3, acidic | 0.00440867 |
| HCCS | holocytochrome c synthase | 0.00440478 |
| KLHL2 | kelch-like family member 2 | 0.00440339 |
| LTF | lactotransferrin | 0.00440076 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00439596 |
| COMMD8 | COMM domain containing 8 | 0.00438463 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.00437309 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -0.0149764 |
| GLOD4 | glyoxalase domain containing 4 | -0.0135649 |
| A2M | alpha-2-macroglobulin | -0.0122485 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.011668 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0110094 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0109171 |
| CPE | carboxypeptidase E | -0.0109046 |
| PROM1 | prominin 1 | -0.0105441 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.0100813 |
| SCG5 | secretogranin V | -0.00998211 |
| MGLL | monoglyceride lipase | -0.00995803 |
| NCAM1 | neural cell adhesion molecule 1 | -0.009805 |
| STON1 | stonin 1 | -0.00979193 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00978305 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00973005 |
| PLN | phospholamban | -0.0097225 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00962115 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00958979 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00954704 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00946549 |
| PRDX2 | peroxiredoxin 2 | -0.00941273 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00936082 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00928699 |
| FHL1 | four and a half LIM domains 1 | -0.00907181 |
| CES1 | carboxylesterase 1 | -0.00898903 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00896495 |
| AOX1 | aldehyde oxidase 1 | -0.00895476 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00894292 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00891634 |
| SFTPA2 | surfactant protein A2 | -0.00880979 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00875034 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00859471 |
| TNS1 | tensin 1 | -0.00858668 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00857853 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00855885 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00853344 |
| DACH1 | dachshund family transcription factor 1 | -0.00850781 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00846631 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00843274 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0083627 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00834483 |
| CHGB | chromogranin B | -0.00833002 |
| TMSB15A | thymosin beta 15a | -0.00830195 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00826296 |
| BCHE | butyrylcholinesterase | -0.00822113 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00818407 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00818131 |
| LUM | lumican | -0.00808659 |
| MAP7 | microtubule-associated protein 7 | -0.00808178 |
| DPT | dermatopontin | -0.00801278 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00800177 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00797408 |
| NDNF | neuron-derived neurotrophic factor | -0.0078803 |
| OLFM4 | olfactomedin 4 | -0.00776439 |
| MGP | matrix Gla protein | -0.00775143 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0076941 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00769311 |
| RYBP | RING1 and YY1 binding protein | -0.00756194 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.0074639 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00744299 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.0074416 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00744076 |
| MYLK | myosin light chain kinase | -0.00732201 |
| PER3 | period circadian clock 3 | -0.00731546 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00730628 |
| ADAMTSL3 | ADAMTS-like 3 | -0.00729715 |
| POSTN | periostin, osteoblast specific factor | -0.00729701 |
| SFTPB | surfactant protein B | -0.00716329 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.00715475 |
| ACKR3 | atypical chemokine receptor 3 | -0.00714864 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0071481 |
| TMEM176B | transmembrane protein 176B | -0.00714194 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00712168 |
| PCP4 | Purkinje cell protein 4 | -0.00710701 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00708978 |
| TFF1 | trefoil factor 1 | -0.00700641 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00698843 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00698565 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00696836 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00691894 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00686126 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00685103 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00684094 |
| KCTD14 | potassium channel tetramerization domain containing 14 | -0.00681226 |
| RBPMS | RNA binding protein with multiple splicing | -0.00677898 |
| DIXDC1 | DIX domain containing 1 | -0.00674485 |
| MSLN | mesothelin | -0.00674251 |
| TBX3 | T-box 3 | -0.00670591 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00668346 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00664436 |
| AOC3 | amine oxidase, copper containing 3 | -0.00663903 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0066295 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.00655427 |
| MMP2 | matrix metallopeptidase 2 | -0.00652634 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00652505 |
| CHRDL1 | chordin-like 1 | -0.00652039 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.00650389 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00648048 |
| ASS1 | argininosuccinate synthase 1 | -0.00646194 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.00643896 |
| CLGN | calmegin | -0.00643851 |
| MEIS2 | Meis homeobox 2 | -0.00642165 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00642009 |
| NPTX2 | neuronal pentraxin II | -0.00641236 |
| HNMT | histamine N-methyltransferase | -0.00639974 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00632926 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00632121 |
| INSR | insulin receptor | -0.00629413 |
| SETD5 | SET domain containing 5 | -0.00624835 |
| IRS2 | insulin receptor substrate 2 | -0.00623734 |
| MYL9 | myosin, light chain 9, regulatory | -0.00623587 |
| GOLGA8H | golgin A8 family, member H | -0.00620817 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00620586 |
| CD200 | CD200 molecule | -0.00620489 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00620375 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00620215 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00619543 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.0061861 |
| NFASC | neurofascin | -0.00612665 |
| CD93 | CD93 molecule | -0.00609193 |
| GPC3 | glypican 3 | -0.00609112 |
| MAOA | monoamine oxidase A | -0.00607615 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00605607 |
| MX1 | MX dynamin-like GTPase 1 | -0.00604443 |
| DES | desmin | -0.00602717 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -0.00601326 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00601111 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00601083 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00600931 |
| GPX3 | glutathione peroxidase 3 | -0.00599129 |
| MEIS1 | Meis homeobox 1 | -0.00595891 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00595775 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00593919 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00592132 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00589407 |
| COLEC12 | collectin sub-family member 12 | -0.00587827 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00586585 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00584549 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.00583495 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00582765 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.0058092 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00580387 |
| TXNIP | thioredoxin interacting protein | -0.00578445 |
| MLPH | melanophilin | -0.00577517 |
| PRPF8 | pre-mRNA processing factor 8 | -0.00575685 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00573271 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.00572755 |
| CPM | carboxypeptidase M | -0.00571456 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00569548 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.00568461 |
| EDNRA | endothelin receptor type A | -0.0056831 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.0056705 |
| DCHS1 | dachsous cadherin-related 1 | -0.00566357 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00566011 |
| TULP3 | tubby like protein 3 | -0.00562106 |
| EPCAM | epithelial cell adhesion molecule | -0.00561354 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00561231 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00560873 |
| NFIB | nuclear factor I/B | -0.0056079 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00560272 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00558516 |
| MTMR11 | myotubularin related protein 11 | -0.00558179 |
| FNBP1 | formin binding protein 1 | -0.00557626 |
| DCLK1 | doublecortin-like kinase 1 | -0.00557079 |
| DCN | decorin | -0.00554455 |
| KLF3-AS1 | KLF3 antisense RNA 1 | -0.00554306 |
| MATN2 | matrilin 2 | -0.00550524 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00548301 |
| MXRA5 | matrix-remodelling associated 5 | -0.00547778 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.00547607 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.00547018 |
| OGN | osteoglycin | -0.00546942 |
| FAM117A | family with sequence similarity 117, member A | -0.00546845 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00544362 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00544042 |
| NAV2 | neuron navigator 2 | -0.00543257 |
| SFTPC | surfactant protein C | -0.00542167 |
| HYOU1 | hypoxia up-regulated 1 | -0.00540781 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00539499 |
| FILIP1L | filamin A interacting protein 1-like | -0.00538992 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.00538749 |
| C7 | complement component 7 | -0.00537472 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00534769 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00533744 |
| NINL | ninein-like | -0.00533497 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00531788 |
| IL1R1 | interleukin 1 receptor, type I | -0.00531361 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00530364 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00530355 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00528196 |
| EXPH5 | exophilin 5 | -0.00528028 |
| PLCB4 | phospholipase C, beta 4 | -0.00527834 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.0052675 |
| BEX4 | brain expressed, X-linked 4 | -0.00523537 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.00522914 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00522567 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00520593 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00519602 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00518862 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00518158 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00517846 |
| CDC25B | cell division cycle 25B | -0.00517682 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00516711 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00516425 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00516306 |
| TSPAN8 | tetraspanin 8 | -0.00515708 |
| CCND2 | cyclin D2 | -0.00515493 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.00515461 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00514571 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.00513414 |
| CD300A | CD300a molecule | -0.00512003 |
| ANGPTL2 | angiopoietin-like 2 | -0.00511766 |
| WASHC5 | WASH complex subunit 5 | -0.0051143 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00510632 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00509467 |
| SDHAP1 | succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 | -0.00507598 |
| SNX7 | sorting nexin 7 | -0.00506533 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00506399 |
| MPDZ | multiple PDZ domain protein | -0.00505965 |
| PLPP3 | phospholipid phosphatase 3 | -0.00505645 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00505617 |
| FOXF1 | forkhead box F1 | -0.0050472 |
| GAB2 | GRB2-associated binding protein 2 | -0.00500872 |
| ISL1 | ISL LIM homeobox 1 | -0.00500268 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00500189 |
| SETBP1 | SET binding protein 1 | -0.00497406 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00496402 |
| PUM1 | pumilio RNA-binding family member 1 | -0.00496305 |
| INTS6 | integrator complex subunit 6 | -0.00494748 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00492328 |
| PNMA8A | PNMA family member 8A | -0.0049095 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 | -0.00490679 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -0.00489285 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00489188 |
| FAM193A | family with sequence similarity 193, member A | -0.00488974 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00487803 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00487767 |
| MT1E | metallothionein 1E | -0.00487737 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00487079 |
| ANOS1 | anosmin 1 | -0.00486738 |
| REEP1 | receptor accessory protein 1 | -0.00486488 |
| TOX3 | TOX high mobility group box family member 3 | -0.00486206 |
| NEFH | neurofilament, heavy polypeptide | -0.00485747 |
| DAPK1 | death-associated protein kinase 1 | -0.00485691 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00484815 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00484454 |
| SSPN | sarcospan | -0.00484146 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00482455 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00482323 |
