| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | TNF receptor-associated factor 4|This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9618) |
| External Link | https://ncbi.nlm.nih.gov/gene/9618 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the TRAF4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SIRT3 | sirtuin 3 | 0.0147754 |
| XIC | X chromosome inactivation center | 0.0141141 |
| MYBPC1 | myosin binding protein C, slow type | 0.0123139 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.012245 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0120884 |
| MMP7 | matrix metallopeptidase 7 | 0.0111405 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0110469 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0109677 |
| MSMB | microseminoprotein, beta- | 0.0106012 |
| KLHL41 | kelch-like family member 41 | 0.0102861 |
| IRS2 | insulin receptor substrate 2 | 0.00999169 |
| CFI | complement factor I | 0.00996362 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00995943 |
| PTN | pleiotrophin | 0.00995794 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00987522 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00987023 |
| SERINC5 | serine incorporator 5 | 0.00965225 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00937454 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00933896 |
| YBX3 | Y box binding protein 3 | 0.00931095 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00911678 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00874629 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00855035 |
| TNNC1 | troponin C type 1 (slow) | 0.00840625 |
| EHD3 | EH-domain containing 3 | 0.00831913 |
| KRT15 | keratin 15, type I | 0.00831572 |
| MSLN | mesothelin | 0.00829109 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00820851 |
| CA3 | carbonic anhydrase III | 0.00819935 |
| CRYAB | crystallin, alpha B | 0.00813721 |
| ARG2 | arginase 2 | 0.00806654 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00803531 |
| OGN | osteoglycin | 0.00802071 |
| VPREB1 | pre-B lymphocyte 1 | 0.00793654 |
| NEFH | neurofilament, heavy polypeptide | 0.00787373 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00781438 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00776994 |
| TNNC2 | troponin C type 2 (fast) | 0.0077695 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00766366 |
| TTN | titin | 0.00766211 |
| SYT1 | synaptotagmin I | 0.00758385 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0075125 |
| CKM | creatine kinase, muscle | 0.00751028 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00743381 |
| MGP | matrix Gla protein | 0.00742586 |
| HOXC6 | homeobox C6 | 0.00741913 |
| S100A11 | S100 calcium binding protein A11 | 0.00740076 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00737353 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00736822 |
| ADD3 | adducin 3 (gamma) | 0.00735493 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.00732806 |
| MME | membrane metallo-endopeptidase | 0.00728919 |
| KLK2 | kallikrein-related peptidase 2 | 0.00727869 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00724662 |
| VCAN | versican | 0.00724613 |
| FILIP1L | filamin A interacting protein 1-like | 0.00723472 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0072227 |
| NDNF | neuron-derived neurotrophic factor | 0.00721963 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00720312 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00719804 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00716735 |
| POU4F1 | POU class 4 homeobox 1 | 0.00714083 |
| WASF1 | WAS protein family, member 1 | 0.00712404 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00711318 |
| GPM6B | glycoprotein M6B | 0.00706908 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.007035 |
| C3 | complement component 3 | 0.00702521 |
| COQ8A | coenzyme Q8A | 0.00702017 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0069223 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00688898 |
| CES1 | carboxylesterase 1 | 0.00687867 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00687786 |
| BTG2 | BTG family, member 2 | 0.0068689 |
| CHRDL1 | chordin-like 1 | 0.00686464 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00684104 |
| SMPX | small muscle protein, X-linked | 0.00679753 |
| APOD | apolipoprotein D | 0.00678557 |
| IL17RB | interleukin 17 receptor B | 0.00676126 |
| TPM3 | tropomyosin 3 | 0.00670629 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00664178 |
| DNTT | DNA nucleotidylexotransferase | 0.00663991 |
| TRIM22 | tripartite motif containing 22 | 0.0066296 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00662917 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00659518 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00656927 |
| CLDN10 | claudin 10 | 0.00656595 |
| PRKCB | protein kinase C, beta | 0.00656396 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00655184 |
| KRT14 | keratin 14, type I | 0.00654799 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00651712 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00650936 |
| MYOT | myotilin | 0.00648023 |
| TMEM135 | transmembrane protein 135 | 0.00647263 |
| RBM34 | RNA binding motif protein 34 | 0.0063562 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00633807 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00633339 |
| LDB3 | LIM domain binding 3 | 0.00632116 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.00630128 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.00630073 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00629235 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00624942 |
| KLK6 | kallikrein-related peptidase 6 | 0.00624145 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00623549 |
| SPRR3 | small proline-rich protein 3 | 0.00622625 |
| OPN3 | opsin 3 | 0.00621079 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00620648 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00619781 |
| FHL1 | four and a half LIM domains 1 | 0.00618213 |
| INAVA | innate immunity activator | 0.00614161 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00613267 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00613137 |
| GAS7 | growth arrest-specific 7 | 0.00610095 |
| ACTN2 | actinin, alpha 2 | 0.00609314 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.0060847 |
| ACP3 | acid phosphatase 3 | 0.00607959 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00605426 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00605097 |
| KLK3 | kallikrein-related peptidase 3 | 0.00604995 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00604578 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00603481 |
| RADX | RPA1 related single stranded DNA binding protein, X-linked | 0.00600984 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00599819 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00598545 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00596783 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.0059374 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.0059287 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00591409 |
| LAMC2 | laminin, gamma 2 | 0.00591338 |
| KRT13 | keratin 13, type I | 0.00589448 |
| ALB | albumin | 0.00586152 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00581824 |
| TSPYL5 | TSPY-like 5 | 0.0058114 |
| IL1A | interleukin 1, alpha | 0.00580756 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00577468 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00576615 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00576022 |
| MUC16 | mucin 16, cell surface associated | 0.00575893 |
| MAGED1 | melanoma antigen family D1 | 0.00575739 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00575201 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00573306 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.00572483 |
| ECM1 | extracellular matrix protein 1 | 0.00569001 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00568438 |
| SLN | sarcolipin | 0.00568132 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00567574 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.00566945 |
| FHOD3 | formin homology 2 domain containing 3 | 0.00566529 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 0.00566281 |
| FMO1 | flavin containing monooxygenase 1 | 0.00566001 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00564864 |
| CAPN3 | calpain 3, (p94) | 0.00562708 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0056258 |
| JAK1 | Janus kinase 1 | 0.00562415 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00561035 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00560411 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00560382 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.00559736 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0055817 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.0055812 |
| STK38 | serine/threonine kinase 38 | 0.0055795 |
| AEBP1 | AE binding protein 1 | 0.00557116 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00556167 |
| PLLP | plasmolipin | 0.00554466 |
| SECISBP2L | SECIS binding protein 2-like | 0.0055403 |
| ZNF195 | zinc finger protein 195 | 0.00553816 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.00552467 |
| CCND2 | cyclin D2 | 0.00549557 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00548998 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.00548778 |
| FGB | fibrinogen beta chain | 0.00547246 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00546041 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.00545228 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00544502 |
| RRAD | Ras-related associated with diabetes | 0.00544307 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00544242 |
| S100P | S100 calcium binding protein P | 0.00543922 |
| MYOM2 | myomesin 2 | 0.00542904 |
| CCN2 | cellular communication network factor 2 | 0.00542463 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00542367 |
| PCDH9 | protocadherin 9 | 0.00541921 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00541738 |
| ANK2 | ankyrin 2, neuronal | 0.00541648 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00541396 |
| PEG10 | paternally expressed 10 | 0.00541221 |
| LDHB | lactate dehydrogenase B | 0.00540476 |
| MAL | mal, T-cell differentiation protein | 0.00539206 |
| HEATR1 | HEAT repeat containing 1 | 0.00538832 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00537292 |
| FAM111A | family with sequence similarity 111, member A | 0.0053578 |
| ANXA11 | annexin A11 | 0.00535276 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00534556 |
| NLGN4X | neuroligin 4, X-linked | 0.00533349 |
| PKP1 | plakophilin 1 | 0.00531275 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00531255 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00530473 |
| RGCC | regulator of cell cycle | 0.00529739 |
| PCBP2 | poly(rC) binding protein 2 | 0.0052903 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00528503 |
| CCDC69 | coiled-coil domain containing 69 | 0.00527001 |
| MX1 | MX dynamin-like GTPase 1 | 0.00524232 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00524109 |
| NELL2 | NEL-like 2 (chicken) | 0.00523816 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00521958 |
| THBS4 | thrombospondin 4 | 0.00521575 |
| AZIN1 | antizyme inhibitor 1 | 0.00521124 |
| TPD52L1 | tumor protein D52-like 1 | 0.00520945 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00518883 |
| TCAP | titin-cap | 0.00518835 |
| PYGM | phosphorylase, glycogen, muscle | 0.005186 |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) | 0.00517584 |
| MYBPC2 | myosin binding protein C, fast type | 0.0051689 |
| STK32B | serine/threonine kinase 32B | 0.00516158 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00515947 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0051509 |
| FBLN5 | fibulin 5 | 0.00514993 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00513315 |
| OPTN | optineurin | 0.00512667 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00511621 |
| KMT5B | lysine methyltransferase 5B | 0.00511227 |
| MATN2 | matrilin 2 | 0.0051071 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00509734 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 | 0.00509005 |
| KLF10 | Kruppel-like factor 10 | 0.00508746 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.00508391 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00507857 |
| ASS1 | argininosuccinate synthase 1 | 0.0050654 |
| MAGEA4 | melanoma antigen family A4 | 0.00504432 |
| TMPRSS11E | transmembrane protease, serine 11E | 0.00504101 |
| FGF13 | fibroblast growth factor 13 | 0.00503966 |
| KRT19 | keratin 19, type I | 0.0050309 |
| SPAG1 | sperm associated antigen 1 | 0.00502758 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00500017 |
| MAOB | monoamine oxidase B | 0.00498904 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00498588 |
| SC5D | sterol-C5-desaturase | 0.00498223 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00497978 |
| SSPN | sarcospan | 0.00497401 |
| RBM38 | RNA binding motif protein 38 | 0.00495947 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00494543 |
| MAGEA3 | melanoma antigen family A3 | 0.00493176 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00491503 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | 0.0048951 |
| SNX1 | sorting nexin 1 | 0.00489443 |
| MAGEA12 | melanoma antigen family A12 | 0.00488322 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.00488217 |
| COBL | cordon-bleu WH2 repeat protein | 0.00487733 |
| KLK11 | kallikrein-related peptidase 11 | 0.00487339 |
| PNMA8A | PNMA family member 8A | 0.0048665 |
| MTF2 | metal response element binding transcription factor 2 | 0.00486469 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00486397 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0184191 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0156562 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0140899 |
| SNX11 | sorting nexin 11 | -0.013687 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0110399 |
| ACKR3 | atypical chemokine receptor 3 | -0.0103638 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00990705 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00990587 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00974465 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00956068 |
| AURKB | aurora kinase B | -0.00947539 |
| PMP22 | peripheral myelin protein 22 | -0.00945065 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00926806 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00913435 |
| ZG16 | zymogen granule protein 16 | -0.0086981 |
| CA2 | carbonic anhydrase II | -0.00867267 |
| DNASE1L3 | deoxyribonuclease I-like 3 | -0.00847003 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00839841 |
| MMP12 | matrix metallopeptidase 12 | -0.00828143 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00810762 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00766362 |
| ALDOA | aldolase A, fructose-bisphosphate | -0.00763268 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00751372 |
| TOX3 | TOX high mobility group box family member 3 | -0.00746378 |
| FST | follistatin | -0.00742121 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | -0.00736445 |
| ARG1 | arginase 1 | -0.00733818 |
| PLEK | pleckstrin | -0.00728838 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00727391 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00726308 |
| HOXB7 | homeobox B7 | -0.0072574 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00724669 |
| TGFB1 | transforming growth factor, beta 1 | -0.0072067 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.0071843 |
| ACTN4 | actinin, alpha 4 | -0.00709903 |
| CLCA1 | chloride channel accessory 1 | -0.00705231 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0070368 |
| SRGN | serglycin | -0.00702577 |
| BCL2A1 | BCL2-related protein A1 | -0.00693337 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00691986 |
| FAM162A | family with sequence similarity 162, member A | -0.00691765 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00687055 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00679755 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00678987 |
| TFRC | transferrin receptor | -0.00676376 |
| CA12 | carbonic anhydrase XII | -0.00675372 |
| HOXB6 | homeobox B6 | -0.00672902 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00657463 |
| CLTB | clathrin, light chain B | -0.0065739 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00649813 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00649551 |
| DEK | DEK proto-oncogene | -0.0064933 |
| POSTN | periostin, osteoblast specific factor | -0.00648616 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00646649 |
| MAP7 | microtubule-associated protein 7 | -0.00645657 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00643822 |
| FOXF1 | forkhead box F1 | -0.00639622 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -0.00639277 |
| S100A7 | S100 calcium binding protein A7 | -0.00635569 |
| PCGF2 | polycomb group ring finger 2 | -0.00634231 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.0062844 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00624651 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00623428 |
| PXDC1 | PX domain containing 1 | -0.00619055 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00617861 |
| TMEM14B | transmembrane protein 14B | -0.00616382 |
| CTSG | cathepsin G | -0.00614394 |
| LOXL2 | lysyl oxidase-like 2 | -0.00612374 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00607858 |
| CBS | cystathionine-beta-synthase | -0.00606321 |
| SFN | stratifin | -0.00605476 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00604326 |
| RGS1 | regulator of G-protein signaling 1 | -0.00600292 |
| JMJD6 | jumonji domain containing 6 | -0.00596916 |
| VEGFC | vascular endothelial growth factor C | -0.00595695 |
| FASN | fatty acid synthase | -0.00589914 |
| LOX | lysyl oxidase | -0.00586063 |
| IRX5 | iroquois homeobox 5 | -0.00584069 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00582337 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | -0.0057817 |
| LASP1 | LIM and SH3 protein 1 | -0.00577649 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00576317 |
| TPM4 | tropomyosin 4 | -0.00574214 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | -0.00572874 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00572019 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | -0.0057121 |
| ANO10 | anoctamin 10 | -0.00570663 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -0.00566842 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00565516 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | -0.00562966 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00562571 |
| GATA6 | GATA binding protein 6 | -0.00560946 |
| FBL | fibrillarin | -0.00559993 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00559567 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00558514 |
| ZNF580 | zinc finger protein 580 | -0.00558105 |
| CBX1 | chromobox homolog 1 | -0.00558088 |
| SYT17 | synaptotagmin XVII | -0.00555211 |
| EPHB2 | EPH receptor B2 | -0.00555128 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00553112 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | -0.00552014 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -0.00551383 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00550114 |
| SNU13 | small nuclear ribonucleoprotein 13 | -0.00546094 |
| ACTN1 | actinin, alpha 1 | -0.00545855 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | -0.00545262 |
| L1CAM | L1 cell adhesion molecule | -0.00542051 |
| ENO1 | enolase 1, (alpha) | -0.00535756 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00534556 |
| CLC | Charcot-Leyden crystal galectin | -0.00532431 |
| CD83 | CD83 molecule | -0.00531942 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.00530489 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0052954 |
| CD164 | CD164 molecule, sialomucin | -0.00528985 |
| CENPM | centromere protein M | -0.00527506 |
| HTRA1 | HtrA serine peptidase 1 | -0.0052702 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00526924 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00526108 |
| HHEX | hematopoietically expressed homeobox | -0.00525303 |
| CENPX | centromere protein X | -0.00524739 |
| CRIP2 | cysteine-rich protein 2 | -0.0052413 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00523561 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00522455 |
| MARCKSL1 | MARCKS-like 1 | -0.00522414 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00521772 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00520208 |
| FABP1 | fatty acid binding protein 1, liver | -0.00517756 |
| RAB32 | RAB32, member RAS oncogene family | -0.00516515 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00514307 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00512317 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00511515 |
| LIMA1 | LIM domain and actin binding 1 | -0.00511051 |
| CALR | calreticulin | -0.00507128 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -0.00505663 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.0050446 |
| CREM | cAMP responsive element modulator | -0.0050426 |
| NAT2 | N-acetyltransferase 2 (arylamine N-acetyltransferase) | -0.00503141 |
| ILK | integrin-linked kinase | -0.0050297 |
| GPR183 | G protein-coupled receptor 183 | -0.00501063 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.00501056 |
| HOXB5 | homeobox B5 | -0.00500933 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -0.00497485 |
| REG1B | regenerating islet-derived 1 beta | -0.00497145 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00495838 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 | -0.00495365 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | -0.00494704 |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | -0.00492901 |
| NXN | nucleoredoxin | -0.00492263 |
| LOR | loricrin | -0.00491621 |
| HDAC9 | histone deacetylase 9 | -0.00491582 |
| SRM | spermidine synthase | -0.00487489 |
| FERMT2 | fermitin family member 2 | -0.00485574 |
| BAAT | bile acid CoA:amino acid N-acyltransferase | -0.00484845 |
| MTA1 | metastasis associated 1 | -0.00484401 |
| SH3BP4 | SH3-domain binding protein 4 | -0.00483449 |
| ATP13A3 | ATPase type 13A3 | -0.0048339 |
| MMP9 | matrix metallopeptidase 9 | -0.00482568 |
| ADORA2B | adenosine A2b receptor | -0.00482016 |
| EVI2A | ecotropic viral integration site 2A | -0.00478591 |
| CCL17 | chemokine (C-C motif) ligand 17 | -0.00478547 |
| KRT10 | keratin 10, type I | -0.00474475 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00473163 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00472996 |
| NLE1 | notchless homolog 1 (Drosophila) | -0.00472978 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00471279 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.00471145 |
| TMEM14A | transmembrane protein 14A | -0.00470156 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00469063 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00469036 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00468219 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.00466147 |
| CALML3 | calmodulin-like 3 | -0.00465547 |
| NVL | nuclear VCP-like | -0.00465445 |
| WBP5 | WW domain binding protein 5 | -0.00465256 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 | -0.00465022 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.00464859 |
| SSR1 | signal sequence receptor, alpha | -0.0046468 |
| SNX6 | sorting nexin 6 | -0.00464396 |
| MCOLN1 | mucolipin 1 | -0.00463813 |
| RGS3 | regulator of G-protein signaling 3 | -0.00463018 |
| ODC1 | ornithine decarboxylase 1 | -0.00462671 |
| HMGB2 | high mobility group box 2 | -0.0046223 |
| SDC1 | syndecan 1 | -0.00461114 |
| SST | somatostatin | -0.00460853 |
| ZNF175 | zinc finger protein 175 | -0.00460752 |
| DUOX2 | dual oxidase 2 | -0.00459882 |
| NSF | N-ethylmaleimide-sensitive factor | -0.00459539 |
| CST7 | cystatin F (leukocystatin) | -0.00459266 |
| LINC00599 | long intergenic non-protein coding RNA 599 | -0.00459093 |
| TSPAN4 | tetraspanin 4 | -0.00458441 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.00457917 |
| RUNX3 | runt-related transcription factor 3 | -0.00456871 |
| SLAMF8 | SLAM family member 8 | -0.00456481 |
| AXL | AXL receptor tyrosine kinase | -0.00453256 |
| CBX6 | chromobox homolog 6 | -0.00452416 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.00452021 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.00450651 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00450564 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | -0.0045038 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00449651 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00449025 |
| PLA2G2D | phospholipase A2, group IID | -0.00447819 |
| PFN2 | profilin 2 | -0.00447805 |
| ADSL | adenylosuccinate lyase | -0.0044735 |
| LYRM4 | LYR motif containing 4 | -0.00447224 |
| FPGS | folylpolyglutamate synthase | -0.00445462 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0044544 |
| HLTF | helicase-like transcription factor | -0.00445177 |
| PLK1 | polo-like kinase 1 | -0.00444217 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | -0.00443961 |
| NNMT | nicotinamide N-methyltransferase | -0.00443538 |
| FGL2 | fibrinogen-like 2 | -0.00442893 |
| IL21R | interleukin 21 receptor | -0.00442774 |
| OLFML2A | olfactomedin-like 2A | -0.0044246 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 | -0.00441344 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.00440919 |
| CYBRD1 | cytochrome b reductase 1 | -0.00440866 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00439987 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00439046 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.0043802 |
| PRSS8 | protease, serine, 8 | -0.00437608 |
| RPA3 | replication protein A3, 14kDa | -0.00436769 |
| PTPRO | protein tyrosine phosphatase, receptor type, O | -0.0043599 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.00434601 |
| PRR7 | proline rich 7 (synaptic) | -0.00433985 |
| F12 | coagulation factor XII (Hageman factor) | -0.00432985 |
| GPR137B | G protein-coupled receptor 137B | -0.00432859 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | -0.00432851 |
| TFR2 | transferrin receptor 2 | -0.00432842 |
| MMP1 | matrix metallopeptidase 1 | -0.0043249 |
| RND3 | Rho family GTPase 3 | -0.00432114 |
| SH2D4A | SH2 domain containing 4A | -0.0043129 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0043111 |
| IGFLR1 | IGF-like family receptor 1 | -0.00430743 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | -0.00429457 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.00429411 |
| SLC2A4RG | SLC2A4 regulator | -0.00428773 |
| CD2 | CD2 molecule | -0.00428471 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -0.00428053 |
| RHOF | ras homolog family member F (in filopodia) | -0.0042724 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.00426794 |
| HOXC8 | homeobox C8 | -0.00426173 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00426113 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00425602 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00425319 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.0042442 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00424198 |
| SSBP3 | single stranded DNA binding protein 3 | -0.00422761 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa | -0.00422647 |
| DIPK1A | divergent protein kinase domain 1A | -0.00421194 |
