TRAF6 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description TNF receptor-associated factor 6, E3 ubiquitin protein ligase|The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported. [provided by RefSeq, Feb 2012] (NCBI Entrez Gene Database, 7189)
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Genes

378 genes differentially expressed following the TRAF6 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ZNF98 zinc finger protein 98 3.41097
ASB9 ankyrin repeat and SOCS box containing 9 3.41097
SVOP SV2 related protein homolog (rat) 3.41097
CD80 CD80 molecule 3.41097
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 3.41097
ISM2 isthmin 2 3.41097
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 3.41097
IL1B interleukin 1, beta 3.41097
PNPLA1 patatin-like phospholipase domain containing 1 3.41097
MMP3 matrix metallopeptidase 3 3.41097
PIWIL3 piwi-like RNA-mediated gene silencing 3 3.41097
PSKH2 protein serine kinase H2 3.41097
ROM1 retinal outer segment membrane protein 1 3.41097
NUTM2A NUT family member 2A 3.41097
NPIPB9 nuclear pore complex interacting protein family, member B9 3.41097
ECM1 extracellular matrix protein 1 3.41097
GNG8 guanine nucleotide binding protein (G protein), gamma 8 3.41097
GPR68 G protein-coupled receptor 68 3.41097
STING1 stimulator of interferon response cGAMP interactor 1 3.41097
GMNC geminin coiled-coil domain containing 3.41097
CCDC177 coiled-coil domain containing 177 3.41097
ITGA11 integrin, alpha 11 3.41097
ANKRD42-DT ANKRD42 divergent transcript 3.41097
C4ORF54 chromosome 4 open reading frame 54 3.41097
OR10A2 olfactory receptor, family 10, subfamily A, member 2 3.32787
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 3.32787
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 3.32787
DDO D-aspartate oxidase 3.32787
PODN podocan 3.32787
KRT26 keratin 26, type I 3.32787
UNC13C unc-13 homolog C (C. elegans) 3.32787
THRSP thyroid hormone responsive 3.32787
PCDHB9 protocadherin beta 9 3.32787
SPINK6 serine peptidase inhibitor, Kazal type 6 3.32787
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.32787
NPAP1 nuclear pore associated protein 1 3.32787
CEMP1 cementum protein 1 3.32787
EVPL envoplakin 3.32787
PRSS36 protease, serine, 36 3.32787
PDZD9 PDZ domain containing 9 3.32787
DPPA3 developmental pluripotency associated 3 3.32787
CHL1 cell adhesion molecule L1-like 3.32787
CLEC5A C-type lectin domain family 5, member A 3.32787
TTLL8 tubulin tyrosine ligase-like family member 8 3.32787
PCDHB1 protocadherin beta 1 3.32787
CRX cone-rod homeobox 3.32787
RXRG retinoid X receptor, gamma 3.32787
ADAT3 adenosine deaminase, tRNA-specific 3 3.32787
SMIM5 small integral membrane protein 5 3.32787
COL15A1 collagen, type XV, alpha 1 3.32787
LRRC63 leucine rich repeat containing 63 3.32787
OXT oxytocin/neurophysin I prepropeptide 3.32787
ATOH1 atonal homolog 1 (Drosophila) 3.32787
ASB10 ankyrin repeat and SOCS box containing 10 3.32787
HBA1 hemoglobin, alpha 1 3.32787
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 3.32787
CABS1 calcium-binding protein, spermatid-specific 1 3.32787
FOLR1 folate receptor 1 (adult) 3.32787
CFHR1 complement factor H-related 1 3.32787
WASL-DT WASL divergent transcript 3.32787
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 3.32787
PNLIPRP1 pancreatic lipase-related protein 1 3.32787
HTRA4 HtrA serine peptidase 4 3.32787
ADRB3 adrenoceptor beta 3 3.32787
TREX2 three prime repair exonuclease 2 3.32787
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 3.32787
RDH8 retinol dehydrogenase 8 (all-trans) 3.32787
TSPAN1 tetraspanin 1 3.32787
C3AR1 complement component 3a receptor 1 3.32787
KIAA0040 KIAA0040 3.32787
SMIM40 small integral membrane protein 40 3.32787
AKAIN1 A-kinase anchor inhibitor 1 3.32787
CFAP73 cilia and flagella associated protein 73 3.32787
EZHIP EZH inhibitory protein 3.32787
UBE2L5 ubiquitin conjugating enzyme E2 L5 3.32787
TMEM270 transmembrane protein 270 3.32787
SPEM2 SPEM family member 2 3.32787
ODAPH odontogenesis associated phosphoprotein 3.32787
RTL9 retrotransposon Gag like 9 3.32787
IMPG1 interphotoreceptor matrix proteoglycan 1 3.32787
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 3.32787
NPIPB8 nuclear pore complex interacting protein family, member B8 3.32787
PRB4 proline-rich protein BstNI subfamily 4 3.32787
REG4 regenerating islet-derived family, member 4 3.32787
KLHL38 kelch-like family member 38 3.32787
FLG filaggrin 3.32787
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 3.32787
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 3.32787
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.32787
SBK3 SH3 domain binding kinase family, member 3 3.32787
IRF5 interferon regulatory factor 5 3.32787
PANX3 pannexin 3 3.32787
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 3.32787
LRRC72 leucine rich repeat containing 72 3.32787
HAL histidine ammonia-lyase 3.32787
C7 complement component 7 3.32787
SASH3 SAM and SH3 domain containing 3 3.32787
CCR3 chemokine (C-C motif) receptor 3 3.32787
MYH13 myosin, heavy chain 13, skeletal muscle 3.32787
ADGRG1 adhesion G protein-coupled receptor G1 3.32787
CATSPER3 cation channel, sperm associated 3 3.32787
CFHR4 complement factor H-related 4 3.32787
NR2F2 nuclear receptor subfamily 2, group F, member 2 3.32787
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 3.32787
CT55 cancer/testis antigen 55 3.32787
OR56A3 olfactory receptor, family 56, subfamily A, member 3 3.32787
EDN2 endothelin 2 3.32787
TESPA1 thymocyte expressed, positive selection associated 1 3.32787
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 3.32787
DUOX2 dual oxidase 2 3.32787
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 3.32787
TIGD3 tigger transposable element derived 3 3.32787
NOG noggin 3.32787
MR1 major histocompatibility complex, class I-related 3.32787
FRS3 fibroblast growth factor receptor substrate 3 3.32787
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 3.32787
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 3.32787
TIGIT T cell immunoreceptor with Ig and ITIM domains 3.32787
APOF apolipoprotein F 3.32787
PCDHGB5 protocadherin gamma subfamily B, 5 3.32787
TMEM132D transmembrane protein 132D 3.32787
KCNK3 potassium channel, two pore domain subfamily K, member 3 3.32787
PRKD2 protein kinase D2 3.32787
IL21R interleukin 21 receptor 3.32787
OR5B2 olfactory receptor, family 5, subfamily B, member 2 3.32787
SLC38A3 solute carrier family 38, member 3 3.32787
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 3.32787
IGIP IgA-inducing protein 3.32787
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 3.32787
C22ORF31 chromosome 22 open reading frame 31 3.32787
SYT5 synaptotagmin V 3.32787
STRC stereocilin 3.32787
SCRIB scribbled planar cell polarity protein 3.32787
ANKRD20A1 ankyrin repeat domain 20 family, member A1 3.32787
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 3.32787
TMEM204 transmembrane protein 204 3.32787
TRIM50 tripartite motif containing 50 3.32787
C2CD4B C2 calcium-dependent domain containing 4B 3.32787
BAHCC1 BAH domain and coiled-coil containing 1 3.32787
COX7B2 cytochrome c oxidase subunit VIIb2 3.32787
VWA7 von Willebrand factor A domain containing 7 3.32787
PNLIPRP3 pancreatic lipase-related protein 3 3.32787
PRSS57 protease, serine, 57 3.32787
CHAD chondroadherin 3.32787
IL17D interleukin 17D 3.32787
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 3.32787
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 3.32787
ALLC allantoicase 3.32787
MSLN mesothelin 3.32787
TGM6 transglutaminase 6 3.32787
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 3.32787
GPR17 G protein-coupled receptor 17 3.32787
OR5A2 olfactory receptor, family 5, subfamily A, member 2 3.32787
FGF10 fibroblast growth factor 10 3.32787
CHRM4 cholinergic receptor, muscarinic 4 3.32787
DUOXA1 dual oxidase maturation factor 1 3.32787
TMEM278 transmembrane protein 278 3.28528
OLFML1 olfactomedin-like 1 3.28528
GAMT guanidinoacetate N-methyltransferase 3.15533
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) 3.1221
MAPK3 mitogen-activated protein kinase 3 3.08454
CEP250 centrosomal protein 250kDa 3.08203
RAB3A RAB3A, member RAS oncogene family 3.06357
ELF2 E74-like factor 2 (ets domain transcription factor) 2.75613
IRS1 insulin receptor substrate 1 2.70852
WLS wntless Wnt ligand secretion mediator 2.69164
GPSM3 G-protein signaling modulator 3 2.68602
ZSWIM4 zinc finger, SWIM-type containing 4 2.68137
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 2.64614
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.63686
TMEM254 transmembrane protein 254 2.6302
GXYLT2 glucoside xylosyltransferase 2 2.57155
PLCB4 phospholipase C, beta 4 2.55282
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13 2.53824
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) 2.50248
AUH AU RNA binding protein/enoyl-CoA hydratase 2.50155
NUSAP1 nucleolar and spindle associated protein 1 2.47768
CDC45 cell division cycle 45 2.46413
BAG3 BCL2-associated athanogene 3 2.45516
KLHDC8A kelch domain containing 8A 2.44213
RETREG1 reticulophagy regulator 1 2.44102
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.42558
SUCLG1 succinate-CoA ligase, alpha subunit 2.39745
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.39086
ATG13 autophagy related 13 2.39036
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.38365
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 2.37662
MXD1 MAX dimerization protein 1 2.37498
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.36434
ADA2 adenosine deaminase 2 2.36434
MTLN mitoregulin 2.35949
YJU2B YJU2 splicing factor homolog B 2.33366
CPXM1 carboxypeptidase X (M14 family), member 1 2.33366
COPG2 coatomer protein complex, subunit gamma 2 2.33245
TBC1D31 TBC1 domain family, member 31 2.32206
RASD1 RAS, dexamethasone-induced 1 2.31666
TEX29 testis expressed 29 2.31666
TMEM238L transmembrane protein 238 like 2.31666
SYP synaptophysin 2.31666
CDH9 cadherin 9, type 2 (T1-cadherin) 2.31666
LGSN lengsin, lens protein with glutamine synthetase domain 2.31666
C10ORF90 chromosome 10 open reading frame 90 2.31666
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2.31666
C11ORF96 chromosome 11 open reading frame 96 2.31666
NWD1 NACHT and WD repeat domain containing 1 2.31269
ZDHHC14 zinc finger, DHHC-type containing 14 2.312
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) 2.30769
SEC14L6 SEC14-like 6 (S. cerevisiae) 2.30055
MOSMO modulator of smoothened 2.26647
MAP2K6 mitogen-activated protein kinase kinase 6 2.2466
ASCC2 activating signal cointegrator 1 complex subunit 2 2.23417
ZNF737 zinc finger protein 737 2.23282
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 2.21651
FXYD1 FXYD domain containing ion transport regulator 1 2.17883
TMEM130 transmembrane protein 130 2.14952
ZNF488 zinc finger protein 488 2.13917
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.13588
TELO2 telomere maintenance 2 2.12632
AQP11 aquaporin 11 2.12344
CCDC157 coiled-coil domain containing 157 2.11539
GPHN gephyrin 2.11336
SAXO6 stabilizer of axonemal microtubules 6 2.1042
GPR173 G protein-coupled receptor 173 2.09599
ATP5MJ ATP synthase membrane subunit j 2.09599
ZNHIT1 zinc finger, HIT-type containing 1 2.09599
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 2.09599
MICU1 mitochondrial calcium uptake 1 2.09176
PRC1 protein regulator of cytokinesis 1 2.08324
ALX3 ALX homeobox 3 2.06539
SCAMP5 secretory carrier membrane protein 5 2.04782
MEI1 meiosis inhibitor 1 2.04648
SMIM11 small integral membrane protein 11 2.0457
GABPA GA binding protein transcription factor, alpha subunit 60kDa 2.03058
MRGBP MRG/MORF4L binding protein 2.02618
VASH2 vasohibin 2 2.02601
NMT1 N-myristoyltransferase 1 2.02153
FAM110C family with sequence similarity 110, member C 2.01306
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 2.01306
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.01258
SAMD14 sterile alpha motif domain containing 14 2.00794
DBNL drebrin-like 2.00472

decreased expression

Symbol Name Standardized Value
LECT2 leukocyte cell-derived chemotaxin 2 -3.41097
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 -3.41097
LRRC3 leucine rich repeat containing 3 -3.41097
HJV hemojuvelin BMP co-receptor -3.41097
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -3.41097
AKAP14 A kinase (PRKA) anchor protein 14 -3.41097
TNS1-AS1 TNS1 antisense RNA 1 -3.41097
PRSS50 protease, serine, 50 -3.41097
TMPRSS7 transmembrane protease, serine 7 -3.32787
SPDYE2B speedy/RINGO cell cycle regulator family member E2B -3.32787
CHADL chondroadherin-like -3.32787
SLCO1C1 solute carrier organic anion transporter family, member 1C1 -3.32787
FPR1 formyl peptide receptor 1 -3.32787
AGBL1 ATP/GTP binding protein-like 1 -3.32787
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 -3.32787
GPBAR1 G protein-coupled bile acid receptor 1 -3.32787
CARNS1 carnosine synthase 1 -3.32787
SP100 SP100 nuclear antigen -3.32787
CXCL13 chemokine (C-X-C motif) ligand 13 -3.32787
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 -3.32787
MYEOV myeloma overexpressed -3.32787
CNTN6 contactin 6 -3.32787
TBX20 T-box 20 -3.32787
LTC4S leukotriene C4 synthase -3.32787
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E -3.32787
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -3.32787
MBLAC1 metallo-beta-lactamase domain containing 1 -3.32787
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -3.32787
ASB12 ankyrin repeat and SOCS box containing 12 -3.32787
EPCIP exosomal polycystin 1 interacting protein -3.32787
TRPV5 transient receptor potential cation channel, subfamily V, member 5 -3.32787
NPFF neuropeptide FF-amide peptide precursor -3.32787
BLNK B-cell linker -3.32787
MOGAT3 monoacylglycerol O-acyltransferase 3 -3.32787
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -3.32787
HIGD1C HIG1 hypoxia inducible domain family, member 1C -3.32787
ZNF703 zinc finger protein 703 -3.32787
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -3.32787
SMIM10 small integral membrane protein 10 -3.32787
DND1 DND microRNA-mediated repression inhibitor 1 -3.32787
THSD8 thrombospondin type 1 domain containing 8 -3.32787
ADAP1 ArfGAP with dual PH domains 1 -3.32787
SPATS1 spermatogenesis associated, serine-rich 1 -3.32787
APOH apolipoprotein H (beta-2-glycoprotein I) -3.32787
ZNRD2 zinc ribbon domain containing 2 -3.29485
A4GALT alpha 1,4-galactosyltransferase -3.23111
BEST1 bestrophin 1 -3.23111
GHRL ghrelin/obestatin prepropeptide -3.22487
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) -3.16078
SLC26A8 solute carrier family 26 (anion exchanger), member 8 -2.9393
FUS FUS RNA binding protein -2.93307
TMEM39B transmembrane protein 39B -2.81976
PABIR3 PABIR family member 3 -2.81488
LRRC19 leucine rich repeat containing 19 -2.7183
NR5A2 nuclear receptor subfamily 5, group A, member 2 -2.70357
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -2.69327
FNIP1 folliculin interacting protein 1 -2.64614
KLKB1 kallikrein B, plasma (Fletcher factor) 1 -2.63511
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.63209
VAV2 vav 2 guanine nucleotide exchange factor -2.5941
OXCT2 3-oxoacid CoA transferase 2 -2.55589
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -2.55589
HPCA hippocalcin -2.55429
TSKU tsukushi, small leucine rich proteoglycan -2.53104
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.524
ZFAND2A zinc finger, AN1-type domain 2A -2.51759
ADGRB1 adhesion G protein-coupled receptor B1 -2.50766
RAMAC RNA guanine-7 methyltransferase activating subunit -2.50248
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease -2.50248
RPL12 ribosomal protein L12 -2.50155
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.46741
MRPS24 mitochondrial ribosomal protein S24 -2.4479
ITLN2 intelectin 2 -2.44743
POU6F2 POU class 6 homeobox 2 -2.44102
THAP3 THAP domain containing, apoptosis associated protein 3 -2.42087
LXN latexin -2.41686
CIP2A cellular inhibitor of PP2A -2.41498
SLC35A4 solute carrier family 35, member A4 -2.40102
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 -2.39036
RIGI RNA sensor RIG-I -2.3894
KDM6A lysine (K)-specific demethylase 6A -2.38365
RPP30 ribonuclease P/MRP 30kDa subunit -2.34664
SLCO5A1 solute carrier organic anion transporter family, member 5A1 -2.3446
DPEP3 dipeptidase 3 -2.34206
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -2.33076
CRABP1 cellular retinoic acid binding protein 1 -2.31666
LINGO1 leucine rich repeat and Ig domain containing 1 -2.31269
UBXN11 UBX domain protein 11 -2.31256
RPS14 ribosomal protein S14 -2.31143
ZNF573 zinc finger protein 573 -2.29265
LTBP2 latent transforming growth factor beta binding protein 2 -2.29083
PROC protein C (inactivator of coagulation factors Va and VIIIa) -2.29083
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 -2.29083
SHISA7 shisa family member 7 -2.29083
STK31 serine/threonine kinase 31 -2.29083
ACRBP acrosin binding protein -2.26908
OLFM3 olfactomedin 3 -2.26908
HSBP1 heat shock factor binding protein 1 -2.25439
TAMALIN trafficking regulator and scaffold protein tamalin -2.25439
TECPR2 tectonin beta-propeller repeat containing 2 -2.2395
RALY RALY heterogeneous nuclear ribonucleoprotein -2.23417
TIMELESS timeless circadian clock -2.23417
NRM nurim (nuclear envelope membrane protein) -2.2299
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 -2.22854
BSG basigin (Ok blood group) -2.22415
RALB v-ral simian leukemia viral oncogene homolog B -2.22415
MRPL34 mitochondrial ribosomal protein L34 -2.21939
TMEM39A transmembrane protein 39A -2.2125
FRY furry homolog (Drosophila) -2.20057
MID2 midline 2 -2.19028
EIF4H eukaryotic translation initiation factor 4H -2.18414
ECPAS Ecm29 proteasome adaptor and scaffold -2.18286
CACNG7 calcium channel, voltage-dependent, gamma subunit 7 -2.13918
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.13889
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 -2.12344
MRPL15 mitochondrial ribosomal protein L15 -2.1201
RPL11 ribosomal protein L11 -2.11552
ERCC6 excision repair cross-complementation group 6 -2.11336
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -2.11317
HPSE heparanase -2.09599
UQCC3 ubiquinol-cytochrome c reductase complex assembly factor 3 -2.09599
EBF4 early B-cell factor 4 -2.09599
MCRIP2 MAPK regulated corepressor interacting protein 2 -2.09561
RNF24 ring finger protein 24 -2.07372
EID1 EP300 interacting inhibitor of differentiation 1 -2.07336
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase -2.06258
MEGF10 multiple EGF-like-domains 10 -2.05186
LARGE2 LARGE xylosyl- and glucuronyltransferase 2 -2.04782
DKKL1 dickkopf-like 1 -2.04648
DVL1 dishevelled segment polarity protein 1 -2.03585
RPL9 ribosomal protein L9 -2.03045
ARHGAP1 Rho GTPase activating protein 1 -2.02264
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -2.02153
COPS5 COP9 signalosome subunit 5 -2.01371
INTS15 integrator complex subunit 15 -2.01306
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -2.01258
RBM15 RNA binding motif protein 15 -2.01258