TREM2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description triggering receptor expressed on myeloid cells 2|This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] (NCBI Entrez Gene Database, 54209)
External Link https://ncbi.nlm.nih.gov/gene/54209
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Genes

499 genes differentially expressed following the TREM2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.024693
PUF60 poly-U binding splicing factor 60KDa 0.0231173
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0135407
SLIT2 slit homolog 2 (Drosophila) 0.0133024
GNAS GNAS complex locus 0.0131155
MBD1 methyl-CpG binding domain protein 1 0.0128768
NVL nuclear VCP-like 0.0118842
FCGBP Fc fragment of IgG binding protein 0.0108242
BCHE butyrylcholinesterase 0.0104386
SCRIB scribbled planar cell polarity protein 0.0103149
REEP1 receptor accessory protein 1 0.00989082
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00980531
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00953675
PTCH1 patched 1 0.00952874
UBE2S ubiquitin-conjugating enzyme E2S 0.00935983
TM9SF3 transmembrane 9 superfamily member 3 0.00912552
PLAT plasminogen activator, tissue 0.00885595
SMC1A structural maintenance of chromosomes 1A 0.00874969
SPON2 spondin 2, extracellular matrix protein 0.00872749
FASN fatty acid synthase 0.00872704
EFNB2 ephrin-B2 0.00858974
CYC1 cytochrome c-1 0.00856838
IGFBP1 insulin-like growth factor binding protein 1 0.00856171
GPM6A glycoprotein M6A 0.00854838
CNPY3 canopy FGF signaling regulator 3 0.00853342
H2AX H2A.X variant histone 0.00851196
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00849103
EPHB2 EPH receptor B2 0.00833218
ITM2A integral membrane protein 2A 0.00826429
C1QB complement component 1, q subcomponent, B chain 0.0082187
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.00820205
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00808381
DACH1 dachshund family transcription factor 1 0.00805084
CP ceruloplasmin (ferroxidase) 0.0080493
ZBTB20 zinc finger and BTB domain containing 20 0.00801925
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00800996
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00798784
BAD BCL2-associated agonist of cell death 0.00798253
AMIGO2 adhesion molecule with Ig-like domain 2 0.00790939
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00788379
KCTD12 potassium channel tetramerization domain containing 12 0.00777758
PBK PDZ binding kinase 0.00771764
BOP1 block of proliferation 1 0.0076837
TNIK TRAF2 and NCK interacting kinase 0.00764128
MLPH melanophilin 0.00763869
ADORA2B adenosine A2b receptor 0.00763377
MTUS1 microtubule associated tumor suppressor 1 0.0076304
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00762905
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.0076239
COL4A5 collagen, type IV, alpha 5 0.00761256
PTN pleiotrophin 0.00759879
NELL1 NEL-like 1 (chicken) 0.00757969
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.0075644
MTDH metadherin 0.00753116
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00749866
SARAF store-operated calcium entry-associated regulatory factor 0.00748938
TMSB15A thymosin beta 15a 0.00741862
LAPTM4B lysosomal protein transmembrane 4 beta 0.00741843
LY6E lymphocyte antigen 6 complex, locus E 0.00740448
GTSE1 G-2 and S-phase expressed 1 0.00738934
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00737165
GPAA1 glycosylphosphatidylinositol anchor attachment 1 0.00735048
ECI2 enoyl-CoA delta isomerase 2 0.00730854
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00730005
SRPX sushi-repeat containing protein, X-linked 0.00729881
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00726137
AGR2 anterior gradient 2 0.00724609
C8ORF33 chromosome 8 open reading frame 33 0.00721359
NLGN4X neuroligin 4, X-linked 0.00720502
KANK2 KN motif and ankyrin repeat domains 2 0.00718703
JAM3 junctional adhesion molecule 3 0.00715939
CDC20 cell division cycle 20 0.00711237
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00709077
CD99 CD99 molecule 0.00707407
AXL AXL receptor tyrosine kinase 0.00705818
NSD2 nuclear receptor binding SET domain protein 2 0.00702671
FOXF1 forkhead box F1 0.00701858
SREBF1 sterol regulatory element binding transcription factor 1 0.00701407
MLF1 myeloid leukemia factor 1 0.00699723
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00696266
PMP22 peripheral myelin protein 22 0.00695574
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.00695494
ZFPM2 zinc finger protein, FOG family member 2 0.00691504
CH25H cholesterol 25-hydroxylase 0.00683872
ANOS1 anosmin 1 0.00682005
C1QA complement component 1, q subcomponent, A chain 0.00677862
DOCK4 dedicator of cytokinesis 4 0.00677787
RAB40B RAB40B, member RAS oncogene family 0.00676225
DLG5 discs, large homolog 5 (Drosophila) 0.00676067
MUC16 mucin 16, cell surface associated 0.00673606
KIF13B kinesin family member 13B 0.00672592
NIPSNAP2 nipsnap homolog 2 0.00670803
OTULINL OTU deubiquitinase with linear linkage specificity like 0.00668284
RHOBTB3 Rho-related BTB domain containing 3 0.0066771
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00667255
LGALS1 lectin, galactoside-binding, soluble, 1 0.00666311
TRMT5 tRNA methyltransferase 5 0.00665069
CHEK2 checkpoint kinase 2 0.00664066
RAD21 RAD21 homolog (S. pombe) 0.00661867
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.00660283
NNMT nicotinamide N-methyltransferase 0.00657962
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00657581
TBXAS1 thromboxane A synthase 1 (platelet) 0.00652285
NKX2-2 NK2 homeobox 2 0.00650668
A2M alpha-2-macroglobulin 0.0064809
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00646827
COL3A1 collagen, type III, alpha 1 0.0064368
TACC3 transforming, acidic coiled-coil containing protein 3 0.00642326
PLEC plectin 0.00642175
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00637837
MOXD1 monooxygenase, DBH-like 1 0.00636353
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00634896
SRSF6 serine/arginine-rich splicing factor 6 0.00634751
DCPS decapping enzyme, scavenger 0.0063457
ASRGL1 asparaginase like 1 0.00634419
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00633329
AURKB aurora kinase B 0.00633073
LAMP5 lysosomal-associated membrane protein family, member 5 0.00631879
NMU neuromedin U 0.00630235
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00629246
CD163 CD163 molecule 0.00628251
DLK1 delta-like 1 homolog (Drosophila) 0.00627899
CSF1R colony stimulating factor 1 receptor 0.00627006
ADD1 adducin 1 (alpha) 0.00626555
HMGB2 high mobility group box 2 0.00622769
WWTR1 WW domain containing transcription regulator 1 0.00621277
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.00621137
PDZD2 PDZ domain containing 2 0.00620601
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00620017
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00618954
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00618276
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00617054
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00614232
ADORA3 adenosine A3 receptor 0.00614185
LPAR1 lysophosphatidic acid receptor 1 0.00609226
SPIN1 spindlin 1 0.00608599
LAMA4 laminin, alpha 4 0.00608169
TBC1D12 TBC1 domain family, member 12 0.00606073
PSRC1 proline/serine-rich coiled-coil 1 0.00605013
KIF20A kinesin family member 20A 0.00603617
PSD3 pleckstrin and Sec7 domain containing 3 0.00603515
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.00600857
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00598654
DHFR dihydrofolate reductase 0.00595961
CTBP1 C-terminal binding protein 1 0.00594691
CLCA1 chloride channel accessory 1 0.00594309
COL6A2 collagen, type VI, alpha 2 0.00593278
FABP1 fatty acid binding protein 1, liver 0.00593209
SPON1 spondin 1, extracellular matrix protein 0.00592894
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.005919
GPSM2 G-protein signaling modulator 2 0.00591691
RGS1 regulator of G-protein signaling 1 0.00591655
EGR3 early growth response 3 0.00591201
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00590621
C3 complement component 3 0.00590294
MTA1 metastasis associated 1 0.00589218
KLHL23 kelch-like family member 23 0.00588163
S100B S100 calcium binding protein B 0.0058774
PDLIM3 PDZ and LIM domain 3 0.00587297
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 0.00586484
COL1A2 collagen, type I, alpha 2 0.00585951
LIMCH1 LIM and calponin homology domains 1 0.00584871
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00583084
BHLHE41 basic helix-loop-helix family, member e41 0.00580811
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00576307
CD302 CD302 molecule 0.00575162
EGR2 early growth response 2 0.00574861
SOX17 SRY (sex determining region Y)-box 17 0.00574173
ZFHX4 zinc finger homeobox 4 0.00573088
MAN1C1 mannosidase, alpha, class 1C, member 1 0.00572768
C3AR1 complement component 3a receptor 1 0.00572577
F2R coagulation factor II (thrombin) receptor 0.00570994
TAC1 tachykinin, precursor 1 0.00569361
MVB12B multivesicular body subunit 12B 0.00568597
SYBU syntabulin (syntaxin-interacting) 0.00568528
CHN2 chimerin 2 0.00568356
BRD2 bromodomain containing 2 0.00567972
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00567475
GAS6 growth arrest-specific 6 0.00567259
RNF130 ring finger protein 130 0.00566455
NID2 nidogen 2 (osteonidogen) 0.00562033
MAP1B microtubule-associated protein 1B 0.00560745
ATP5ME ATP synthase membrane subunit e 0.00559609
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.00558327
RCAN2 regulator of calcineurin 2 0.00558012
QKI QKI, KH domain containing, RNA binding 0.0055734
ADGRF5 adhesion G protein-coupled receptor F5 0.00557244
TUBA1A tubulin, alpha 1a 0.00556619
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00556156
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00555061
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00554872
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00553887
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00553855
PRKCSH protein kinase C substrate 80K-H 0.00550804
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00549259
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.00547867
BIN1 bridging integrator 1 0.00547512
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00546403
HELLS helicase, lymphoid-specific 0.00545311
DPYSL3 dihydropyrimidinase-like 3 0.00544069
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.0054332
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.00543078
CHP2 calcineurin-like EF-hand protein 2 0.00543016
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00542868
SCG5 secretogranin V 0.00540776
ANKRD11 ankyrin repeat domain 11 0.00540715
TRIP13 thyroid hormone receptor interactor 13 0.00540314
ADGRG2 adhesion G protein-coupled receptor G2 0.00540245
MYO5C myosin VC 0.00539132
OSBPL3 oxysterol binding protein-like 3 0.00538713
STAB1 stabilin 1 0.00538461
SPA17 sperm autoantigenic protein 17 0.00538401
FRZB frizzled-related protein 0.00538026
SIDT2 SID1 transmembrane family, member 2 0.00535878
VSIG4 V-set and immunoglobulin domain containing 4 0.00534088
CDC45 cell division cycle 45 0.00533976
KIAA0232 KIAA0232 0.00533205
RAB20 RAB20, member RAS oncogene family 0.00532653
CHD4 chromodomain helicase DNA binding protein 4 0.00532262
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.00532082
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00532052
HMGB3 high mobility group box 3 0.00530728
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.0052975
NID1 nidogen 1 0.00527964
COL14A1 collagen, type XIV, alpha 1 0.00526266
MFAP2 microfibrillar-associated protein 2 0.00525359
DGAT1 diacylglycerol O-acyltransferase 1 0.00523835
HAMP hepcidin antimicrobial peptide 0.00523341
NINJ2 ninjurin 2 0.00523274
CFH complement factor H 0.00522572
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.00521233
CIT citron rho-interacting serine/threonine kinase 0.0052039
LIG1 ligase I, DNA, ATP-dependent 0.00517347
PRUNE2 prune homolog 2 (Drosophila) 0.00517347
PARP4 poly (ADP-ribose) polymerase family, member 4 0.00517114
HMGN2 high mobility group nucleosomal binding domain 2 0.00516818
SPP1 secreted phosphoprotein 1 0.00516715
SYNGR3 synaptogyrin 3 0.00516627
KRT20 keratin 20, type I 0.00515872
TRIM28 tripartite motif containing 28 0.00515675
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.00515483
MXRA5 matrix-remodelling associated 5 0.00514453
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.00514359
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00514104
SNX7 sorting nexin 7 0.00513381
SRPRA SRP receptor subunit alpha 0.0051261
TTC12 tetratricopeptide repeat domain 12 0.00512592
ANKRD10 ankyrin repeat domain 10 0.00512507
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00512488
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.00511515

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -0.0228748
S100A9 S100 calcium binding protein A9 -0.02012
CSTA cystatin A (stefin A) -0.0197699
KRT17 keratin 17, type I -0.0161666
KRT14 keratin 14, type I -0.0160809
TPD52L1 tumor protein D52-like 1 -0.0157777
LTF lactotransferrin -0.0152698
ADM adrenomedullin -0.0150966
KRT5 keratin 5, type II -0.0147948
S100P S100 calcium binding protein P -0.0145702
S100A12 S100 calcium binding protein A12 -0.0137085
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.0136439
ISG20 interferon stimulated exonuclease gene 20kDa -0.0134439
KRT15 keratin 15, type I -0.0132725
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0131976
KRT6A keratin 6A, type II -0.0130837
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0129795
SPRR3 small proline-rich protein 3 -0.0128292
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0123307
MMP9 matrix metallopeptidase 9 -0.0122057
SPRR1B small proline-rich protein 1B -0.0121712
KRT13 keratin 13, type I -0.0121304
CRISP3 cysteine-rich secretory protein 3 -0.0120193
KRT6B keratin 6B, type II -0.0119714
IL1RN interleukin 1 receptor antagonist -0.0119545
ELANE elastase, neutrophil expressed -0.0118427
MT1X metallothionein 1X -0.011776
FXYD3 FXYD domain containing ion transport regulator 3 -0.0114985
TM4SF1 transmembrane 4 L six family member 1 -0.0112727
SLPI secretory leukocyte peptidase inhibitor -0.011252
BTG1 B-cell translocation gene 1, anti-proliferative -0.0110201
ANXA1 annexin A1 -0.0107698
TRIM29 tripartite motif containing 29 -0.0107311
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0107002
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0106706
KRT16 keratin 16, type I -0.0106312
SPRR1A small proline-rich protein 1A -0.0106096
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.0105445
ABLIM1 actin binding LIM protein 1 -0.0103342
ADIRF adipogenesis regulatory factor -0.010279
RND3 Rho family GTPase 3 -0.0102666
TACSTD2 tumor-associated calcium signal transducer 2 -0.0102197
DEFA4 defensin, alpha 4, corticostatin -0.0102105
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.0100642
MSMB microseminoprotein, beta- -0.0100434
DSG3 desmoglein 3 -0.010027
GSTP1 glutathione S-transferase pi 1 -0.00993558
BEX1 brain expressed, X-linked 1 -0.00988553
C10ORF10 chromosome 10 open reading frame 10 -0.00983905
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00983586
TRIM22 tripartite motif containing 22 -0.00979175
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00974281
CD52 CD52 molecule -0.00973807
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00961196
SPRR2B small proline-rich protein 2B -0.00959807
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00955427
MXI1 MAX interactor 1, dimerization protein -0.00939072
BCL2A1 BCL2-related protein A1 -0.00934284
RHCG Rh family, C glycoprotein -0.00912036
RAB29 RAB29, member RAS oncogene family -0.00907489
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00905197
HBD hemoglobin, delta -0.0090019
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00899505
CSTB cystatin B (stefin B) -0.0088669
IRF6 interferon regulatory factor 6 -0.00885168
TP53I3 tumor protein p53 inducible protein 3 -0.008802
CDK14 cyclin-dependent kinase 14 -0.00863884
AZU1 azurocidin 1 -0.00850573
MT1G metallothionein 1G -0.00849747
PAX5 paired box 5 -0.00849369
MPO myeloperoxidase -0.00847741
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00845261
RRAGD Ras-related GTP binding D -0.00844903
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00841296
LYZ lysozyme -0.00840256
PKP1 plakophilin 1 -0.00832869
PERP PERP, TP53 apoptosis effector -0.00828802
RALB v-ral simian leukemia viral oncogene homolog B -0.00826248
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00824575
SINHCAF SIN3-HDAC complex associated factor -0.00820346
CD79B CD79b molecule, immunoglobulin-associated beta -0.00818229
PPL periplakin -0.0081771
RHOB ras homolog family member B -0.00812429
SIRPA signal-regulatory protein alpha -0.00807898
HK2 hexokinase 2 -0.00806892
CD9 CD9 molecule -0.00806306
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00804993
RBM34 RNA binding motif protein 34 -0.00804991
IGFBP5 insulin-like growth factor binding protein 5 -0.00804058
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00800436
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00800305
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00799959
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00796126
MT1HL1 metallothionein 1H-like 1 -0.00794993
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00787172
STC2 stanniocalcin 2 -0.007867
SFRP1 secreted frizzled-related protein 1 -0.00785551
S100A7 S100 calcium binding protein A7 -0.00784792
IL32 interleukin 32 -0.00783723
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00782624
TGIF1 TGFB-induced factor homeobox 1 -0.00782497
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00781707
ANO10 anoctamin 10 -0.00779045
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -0.00775843
STX7 syntaxin 7 -0.00759969
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00758838
HIST1H2AC histone cluster 1, H2ac -0.00758288
ANXA3 annexin A3 -0.00757934
HIST1H2BD histone cluster 1, H2bd -0.00752803
COG7 component of oligomeric golgi complex 7 -0.00752703
S100A2 S100 calcium binding protein A2 -0.00749203
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00745312
DUSP5 dual specificity phosphatase 5 -0.00741876
FABP4 fatty acid binding protein 4, adipocyte -0.0074179
S100A14 S100 calcium binding protein A14 -0.0074056
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00737541
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00734169
DAXX death-domain associated protein -0.00733343
NCF2 neutrophil cytosolic factor 2 -0.00730972
MT1E metallothionein 1E -0.00727491
HDDC2 HD domain containing 2 -0.00725367
HBB hemoglobin, beta -0.00724596
PLSCR1 phospholipid scramblase 1 -0.00723962
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00722795
RIPOR2 RHO family interacting cell polarization regulator 2 -0.00721323
PDZK1IP1 PDZK1 interacting protein 1 -0.00720224
PI3 peptidase inhibitor 3, skin-derived -0.00719809
PRTN3 proteinase 3 -0.00719434
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00717814
TCL1A T-cell leukemia/lymphoma 1A -0.00715267
ORM1 orosomucoid 1 -0.00714471
SORBS2 sorbin and SH3 domain containing 2 -0.0071423
LYPD3 LY6/PLAUR domain containing 3 -0.00709583
AIM2 absent in melanoma 2 -0.00707675
VSNL1 visinin-like 1 -0.0070162
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00701358
IGFBP6 insulin-like growth factor binding protein 6 -0.0069912
WIF1 WNT inhibitory factor 1 -0.00698551
CD59 CD59 molecule, complement regulatory protein -0.0069835
GM2A GM2 ganglioside activator -0.00698113
CHIT1 chitinase 1 (chitotriosidase) -0.00697978
NDRG1 N-myc downstream regulated 1 -0.00695779
BLNK B-cell linker -0.00695577
MT1H metallothionein 1H -0.00693744
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00692966
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00690864
VPREB3 pre-B lymphocyte 3 -0.00689311
MREG melanoregulin -0.00688655
CLCA2 chloride channel accessory 2 -0.00688592
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00686742
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00685065
LAMC2 laminin, gamma 2 -0.00683752
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00682164
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00681778
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma -0.00678482
MALL mal, T-cell differentiation protein-like -0.00678369
TERF2 telomeric repeat binding factor 2 -0.00677112
AHSP alpha hemoglobin stabilizing protein -0.00676816
POU2AF1 POU class 2 associating factor 1 -0.00676386
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00674005
RGS13 regulator of G-protein signaling 13 -0.00673195
CD19 CD19 molecule -0.0067317
TDRD12 tudor domain containing 12 -0.00669916
AFTPH aftiphilin -0.006688
CAST calpastatin -0.00668241
CNN3 calponin 3, acidic -0.00668221
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00667121
FGG fibrinogen gamma chain -0.006656
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00661765
PSCA prostate stem cell antigen -0.00659818
CRABP2 cellular retinoic acid binding protein 2 -0.0065941
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.0065835
CTSG cathepsin G -0.00656294
CLIC3 chloride intracellular channel 3 -0.00655183
MAL mal, T-cell differentiation protein -0.00654745
YPEL5 yippee-like 5 (Drosophila) -0.0065413
HSPA1A heat shock 70kDa protein 1A -0.00649757
SH3YL1 SH3 and SYLF domain containing 1 -0.0064829
EAF2 ELL associated factor 2 -0.00647441
RFTN1 raftlin, lipid raft linker 1 -0.00645636
SIRT3 sirtuin 3 -0.00643015
RAB21 RAB21, member RAS oncogene family -0.00642172
FOLR1 folate receptor 1 (adult) -0.00641156
CCN3 cellular communication network factor 3 -0.00640326
ABHD5 abhydrolase domain containing 5 -0.00637692
LAMP3 lysosomal-associated membrane protein 3 -0.00635832
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00635396
CCNG2 cyclin G2 -0.00634724
DGKA diacylglycerol kinase, alpha 80kDa -0.00634641
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00633747
TSPAN1 tetraspanin 1 -0.00632907
GJA1 gap junction protein, alpha 1, 43kDa -0.00632698
POSTN periostin, osteoblast specific factor -0.0063228
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00631559
MMP8 matrix metallopeptidase 8 -0.00627214
ZFP36L2 ZFP36 ring finger protein-like 2 -0.00627109
ALB albumin -0.00626365
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00626361
NFE2L1 nuclear factor, erythroid 2-like 1 -0.00626249
RPS26 ribosomal protein S26 -0.00625342
IFI30 interferon, gamma-inducible protein 30 -0.00623581
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00621013
STK26 serine/threonine protein kinase 26 -0.00617963
STATH statherin -0.00615861
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00615833
RNASE3 ribonuclease, RNase A family, 3 -0.00614643
PDE8B phosphodiesterase 8B -0.00614112
MT1F metallothionein 1F -0.00613803
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00613007
TP63 tumor protein p63 -0.00612762
GRN granulin -0.00610228
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00610094
RAB9A RAB9A, member RAS oncogene family -0.0060984
LY6D lymphocyte antigen 6 complex, locus D -0.00608537
CORO1C coronin, actin binding protein, 1C -0.0060819
DIO1 deiodinase, iodothyronine, type I -0.00606756
XIC X chromosome inactivation center -0.00604701
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.0060422
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00603541
COCH cochlin -0.00602162
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00600783
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00598888
DNM1L dynamin 1-like -0.00598597
QPCT glutaminyl-peptide cyclotransferase -0.00598577
TARP TCR gamma alternate reading frame protein -0.00596994
KLHL24 kelch-like family member 24 -0.00596943
GABARAPL2 GABA(A) receptor-associated protein-like 2 -0.0059682
ACP1 acid phosphatase 1, soluble -0.00595654
SH3GLB1 SH3-domain GRB2-like endophilin B1 -0.00595346
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00595287
BMP2 bone morphogenetic protein 2 -0.00595165
PRAME preferentially expressed antigen in melanoma -0.00593276
CEMIP cell migration inducing protein, hyaluronan binding -0.00592941
NOP10 NOP10 ribonucleoprotein -0.00592376
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.0058963
HLA-DOB major histocompatibility complex, class II, DO beta -0.00586439
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00585783
ELMO1 engulfment and cell motility 1 -0.00585758
PCLO piccolo presynaptic cytomatrix protein -0.00583666
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00583271
CTSE cathepsin E -0.0058227
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -0.00581589
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00581448
TMEM131L transmembrane 131 like -0.0057961
CA2 carbonic anhydrase II -0.00579404
G0S2 G0/G1 switch 2 -0.00578646
CD38 CD38 molecule -0.0057771
IFIH1 interferon induced with helicase C domain 1 -0.00577664
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 -0.00577115