TRIM24_knockout_300_GSE19675 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE19675
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Genes

600 genes differentially expressed following the TRIM24_knockout_300_GSE19675 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
CDC123 cell division cycle 123 3.79801
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 3.62242
IK IK cytokine, down-regulator of HLA II 3.5388
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 3.47888
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 3.43969
ZNF565 zinc finger protein 565 3.43337
ZMPSTE24 zinc metallopeptidase STE24 3.35173
RPP40 ribonuclease P/MRP 40kDa subunit 3.2159
CRLF3 cytokine receptor-like factor 3 3.09689
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 3.06495
CDPF1 cysteine-rich, DPF motif domain containing 1 3.03897
MAGEH1 melanoma antigen family H1 2.95872
CCDC3 coiled-coil domain containing 3 2.91285
MED20 mediator complex subunit 20 2.8682
STX16 syntaxin 16 2.79046
MBD1 methyl-CpG binding domain protein 1 2.75471
PRELID1 PRELI domain containing 1 2.70939
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 2.70599
CAMTA2 calmodulin binding transcription activator 2 2.70071
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 2.7004
SLC30A9 solute carrier family 30 (zinc transporter), member 9 2.67079
CFAP53 cilia and flagella associated protein 53 2.65421
COA3 cytochrome c oxidase assembly factor 3 2.6539
TCAIM T cell activation inhibitor, mitochondrial 2.65221
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.64999
GNL1 guanine nucleotide binding protein-like 1 2.62676
MSL2 male-specific lethal 2 homolog (Drosophila) 2.62307
XAF1 XIAP associated factor 1 2.61851
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.60972
GSTM4 glutathione S-transferase mu 4 2.59959
PLCL2 phospholipase C-like 2 2.59657
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.59314
IFI16 interferon, gamma-inducible protein 16 2.57677
PPP1R21 protein phosphatase 1, regulatory subunit 21 2.56417
COPZ1 coatomer protein complex, subunit zeta 1 2.54648
ZFAND1 zinc finger, AN1-type domain 1 2.54276
RFWD3 ring finger and WD repeat domain 3 2.52744
OLFM1 olfactomedin 1 2.52505
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 2.4884
CBFB core-binding factor, beta subunit 2.48728
C2 complement component 2 2.45498
BABAM1 BRISC and BRCA1 A complex member 1 2.44147
C11ORF58 chromosome 11 open reading frame 58 2.44064
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 2.4373
LMTK2 lemur tyrosine kinase 2 2.42262
CD151 CD151 molecule (Raph blood group) 2.39808
HDAC1 histone deacetylase 1 2.38323
SCARB2 scavenger receptor class B, member 2 2.36694
KIAA1143 KIAA1143 2.35308
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa 2.3445
RPA1 replication protein A1, 70kDa 2.34332
NANS N-acetylneuraminic acid synthase 2.33701
ZNF275 zinc finger protein 275 2.33612
UNC93B1 unc-93 homolog B1 (C. elegans) 2.33423
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.32973
RAB24 RAB24, member RAS oncogene family 2.32114
GBP3 guanylate binding protein 3 2.30827
RGN regucalcin 2.30649
FBXO25 F-box protein 25 2.29814
HPS4 Hermansky-Pudlak syndrome 4 2.29114
AP3M1 adaptor-related protein complex 3, mu 1 subunit 2.27591
LAPTM4A lysosomal protein transmembrane 4 alpha 2.27053
RRAS2 related RAS viral (r-ras) oncogene homolog 2 2.25984
TRAPPC2L trafficking protein particle complex 2-like 2.25951
LARP4 La ribonucleoprotein domain family, member 4 2.24167
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) 2.23729
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 2.23607
AARS alanyl-tRNA synthetase 2.22981
FUCA1 fucosidase, alpha-L- 1, tissue 2.22827
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.22567
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.22086
MTPN myotrophin 2.21693
MFSD5 major facilitator superfamily domain containing 5 2.20864
TMCC3 transmembrane and coiled-coil domain family 3 2.20393
FAM114A1 family with sequence similarity 114, member A1 2.19657
TMEM261 transmembrane protein 261 2.18702
MASP2 mannan-binding lectin serine peptidase 2 2.18404
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.18258
TMEM9B TMEM9 domain family, member B 2.17904
RFC2 replication factor C (activator 1) 2, 40kDa 2.17863
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 2.17738
C14ORF159 chromosome 14 open reading frame 159 2.17704
DNPEP aspartyl aminopeptidase 2.15759
BAX BCL2-associated X protein 2.15348
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.14775
TGFBI transforming growth factor, beta-induced, 68kDa 2.1448
C7ORF60 chromosome 7 open reading frame 60 2.142
ONECUT2 one cut homeobox 2 2.14016
GOLGA7 golgin A7 2.13799
CFL1 cofilin 1 (non-muscle) 2.13571
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.13166
EXOSC10 exosome component 10 2.12806
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 2.11424
RCAN1 regulator of calcineurin 1 2.11423
GPSM2 G-protein signaling modulator 2 2.1135
RPUSD3 RNA pseudouridylate synthase domain containing 3 2.11189
ACSL4 acyl-CoA synthetase long-chain family member 4 2.10493
ZFP62 ZFP62 zinc finger protein 2.10464
PCBP1 poly(rC) binding protein 1 2.09029
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.08826
UBA5 ubiquitin-like modifier activating enzyme 5 2.08353
MCL1 myeloid cell leukemia 1 2.08168
SEC23B Sec23 homolog B (S. cerevisiae) 2.08065
ZNF467 zinc finger protein 467 2.07822
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 2.06261
LDLRAP1 low density lipoprotein receptor adaptor protein 1 2.05938
ANXA3 annexin A3 2.05855
ZDHHC24 zinc finger, DHHC-type containing 24 2.04478
SRM spermidine synthase 2.03965
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.03606
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.03405
KAT2A K(lysine) acetyltransferase 2A 2.03224
ACBD5 acyl-CoA binding domain containing 5 2.03092
PRAMEF12 PRAME family member 12 2.02654
CCNG1 cyclin G1 2.02643
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.02523
NCOA3 nuclear receptor coactivator 3 2.01701
ZNF266 zinc finger protein 266 2.00427
C9ORF91 chromosome 9 open reading frame 91 2.00382
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 2.00347
IFI35 interferon-induced protein 35 2.00274
PEF1 penta-EF-hand domain containing 1 1.99742
ZNF280D zinc finger protein 280D 1.99639
PHKG2 phosphorylase kinase, gamma 2 (testis) 1.99624
DSE dermatan sulfate epimerase 1.99335
IGIP IgA-inducing protein 1.98669
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 1.98419
ABHD11 abhydrolase domain containing 11 1.98048
EIF3B eukaryotic translation initiation factor 3, subunit B 1.98044
DOCK1 dedicator of cytokinesis 1 1.97868
SHISA5 shisa family member 5 1.97627
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 1.96739
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 1.96621
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 1.96521
SDCBP syndecan binding protein (syntenin) 1.959
POLB polymerase (DNA directed), beta 1.95897
C5ORF24 chromosome 5 open reading frame 24 1.95836
ENDOG endonuclease G 1.95657
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.95344
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.93916
ZNHIT6 zinc finger, HIT-type containing 6 1.93877
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 1.92958
CDK11A cyclin-dependent kinase 11A 1.92366
HAPLN4 hyaluronan and proteoglycan link protein 4 1.92017
ELF4 E74-like factor 4 (ets domain transcription factor) 1.91875
DERL1 derlin 1 1.91406
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.91081
SAR1A secretion associated, Ras related GTPase 1A 1.90988
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.90926
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.90579
IRF7 interferon regulatory factor 7 1.90346
NKAP NFKB activating protein 1.9019
SNX10 sorting nexin 10 1.89916
ZC3H10 zinc finger CCCH-type containing 10 1.899
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.89867
NELFB negative elongation factor complex member B 1.8985
SPINT2 serine peptidase inhibitor, Kunitz type, 2 1.89492
ELAC2 elaC ribonuclease Z 2 1.89324
USO1 USO1 vesicle transport factor 1.89148
NUDC nudC nuclear distribution protein 1.88728
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.88531
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 1.88104
LMO2 LIM domain only 2 (rhombotin-like 1) 1.87807
NHLRC3 NHL repeat containing 3 1.87188
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 1.86829
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 1.86635
UBAP2 ubiquitin associated protein 2 1.85532
UBE3B ubiquitin protein ligase E3B 1.8532
COMMD3 COMM domain containing 3 1.85288
RBBP6 retinoblastoma binding protein 6 1.85217
MARK2 MAP/microtubule affinity-regulating kinase 2 1.85137
TEKT5 tektin 5 1.84598
SPARCL1 SPARC-like 1 (hevin) 1.84582
ERMP1 endoplasmic reticulum metallopeptidase 1 1.84569
SPNS1 spinster homolog 1 (Drosophila) 1.83396
RANBP1 RAN binding protein 1 1.83224
TBRG1 transforming growth factor beta regulator 1 1.83031
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 1.82611
HDAC4 histone deacetylase 4 1.82475
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.82473
IRF5 interferon regulatory factor 5 1.81902
TMEM176A transmembrane protein 176A 1.81759
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 1.81729
NPDC1 neural proliferation, differentiation and control, 1 1.81633
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 1.81611
SSB Sjogren syndrome antigen B (autoantigen La) 1.81576
MBL2 mannose-binding lectin (protein C) 2, soluble 1.81574
SCAMP2 secretory carrier membrane protein 2 1.80866
UGDH UDP-glucose 6-dehydrogenase 1.80839
BMP2 bone morphogenetic protein 2 1.80761
F13B coagulation factor XIII, B polypeptide 1.80621
STAP2 signal transducing adaptor family member 2 1.8041
GRAMD4 GRAM domain containing 4 1.80257
PARP3 poly (ADP-ribose) polymerase family, member 3 1.80211
PAPOLA poly(A) polymerase alpha 1.80002
CENPJ centromere protein J 1.79838
ALG3 ALG3, alpha-1,3- mannosyltransferase 1.79653
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.79598
AOAH acyloxyacyl hydrolase (neutrophil) 1.79404
FAM213A family with sequence similarity 213, member A 1.79215
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 1.78843
YARS tyrosyl-tRNA synthetase 1.78464
OTUD4 OTU deubiquitinase 4 1.78308
ZNF143 zinc finger protein 143 1.78213
PDDC1 Parkinson disease 7 domain containing 1 1.7812
AMY2A amylase, alpha 2A (pancreatic) 1.77997
ARRB1 arrestin, beta 1 1.77574
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 1.77418
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 1.77267
NRROS negative regulator of reactive oxygen species 1.77205
EPS15 epidermal growth factor receptor pathway substrate 15 1.7712
FOXA2 forkhead box A2 1.77118
IRF6 interferon regulatory factor 6 1.77008
APOF apolipoprotein F 1.76742
KRTCAP2 keratinocyte associated protein 2 1.76401
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.76259
MAD2L1BP MAD2L1 binding protein 1.75585
ACSM1 acyl-CoA synthetase medium-chain family member 1 1.75506
HARS histidyl-tRNA synthetase 1.75398
RREB1 ras responsive element binding protein 1 1.75392
TRAPPC6B trafficking protein particle complex 6B 1.75271
TRIM11 tripartite motif containing 11 1.74653
ST7 suppression of tumorigenicity 7 1.74489
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.73884
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 1.73775
LY6E lymphocyte antigen 6 complex, locus E 1.73459
PNPO pyridoxamine 5'-phosphate oxidase 1.73101
PDGFA platelet-derived growth factor alpha polypeptide 1.73029
STK4 serine/threonine kinase 4 1.7289
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 1.72634
MFN1 mitofusin 1 1.72228
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 1.7166
PGAM5 phosphoglycerate mutase family member 5 1.71603
HEXB hexosaminidase B (beta polypeptide) 1.71587
LRRC3 leucine rich repeat containing 3 1.71375
WARS tryptophanyl-tRNA synthetase 1.71282
BLMH bleomycin hydrolase 1.71248
TMEM141 transmembrane protein 141 1.71222
ZNF778 zinc finger protein 778 1.70656
SLPI secretory leukocyte peptidase inhibitor 1.70628
MED19 mediator complex subunit 19 1.70549
TUSC2 tumor suppressor candidate 2 1.70474
VSIG4 V-set and immunoglobulin domain containing 4 1.70345
METAP1 methionyl aminopeptidase 1 1.70112
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.70071
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 1.69954
CXCL16 chemokine (C-X-C motif) ligand 16 1.69702
STAT1 signal transducer and activator of transcription 1, 91kDa 1.69414
IGFALS insulin-like growth factor binding protein, acid labile subunit 1.69306
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 1.693
GM2A GM2 ganglioside activator 1.69166
SPATS2 spermatogenesis associated, serine-rich 2 1.69107
INTS2 integrator complex subunit 2 1.68574
MEF2BNB MEF2B neighbor 1.68423
ILF2 interleukin enhancer binding factor 2 1.67881
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 1.67705
TMEM179B transmembrane protein 179B 1.67662
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.67219
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 1.67002
SUGP1 SURP and G patch domain containing 1 1.66831
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 1.66776
RNPEP arginyl aminopeptidase (aminopeptidase B) 1.66559
CSF1R colony stimulating factor 1 receptor 1.66478
CDK10 cyclin-dependent kinase 10 1.66278
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 1.66273
SELK selenoprotein K 1.66168
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 1.65619
FLNA filamin A, alpha 1.65478
TADA1 transcriptional adaptor 1 1.65409
GTPBP4 GTP binding protein 4 1.65114
WBP4 WW domain binding protein 4 1.6495
NKIRAS2 NFKB inhibitor interacting Ras-like 2 1.64928
FAF2 Fas associated factor family member 2 1.64906
PLXNB1 plexin B1 1.64505
TEC tec protein tyrosine kinase 1.6448
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.64215
MYDGF myeloid-derived growth factor 1.64125
SLC39A3 solute carrier family 39 (zinc transporter), member 3 1.64003
SERP1 stress-associated endoplasmic reticulum protein 1 1.64001
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 1.63919
RARB retinoic acid receptor, beta 1.63815
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 1.63385
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.63265
VIMP VCP-interacting membrane selenoprotein 1.63221
RHOJ ras homolog family member J 1.63084
EDC4 enhancer of mRNA decapping 4 1.62744
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 1.62302
SPOP speckle-type POZ protein 1.61867
RNASEH2A ribonuclease H2, subunit A 1.61813
BCAR1 breast cancer anti-estrogen resistance 1 1.61605
HPS5 Hermansky-Pudlak syndrome 5 1.61499
CHPF2 chondroitin polymerizing factor 2 1.61449
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 1.61309
FAM208A family with sequence similarity 208, member A 1.61245
AP1AR adaptor-related protein complex 1 associated regulatory protein 1.61114
F12 coagulation factor XII (Hageman factor) 1.60856
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.6025
EIF5A eukaryotic translation initiation factor 5A 1.60179
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.60063
PINK1 PTEN induced putative kinase 1 1.59891

decreased expression

Symbol Name Standardized Value
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -3.71329
FCGRT Fc fragment of IgG, receptor, transporter, alpha -3.70761
ANKRD28 ankyrin repeat domain 28 -3.38283
OAT ornithine aminotransferase -3.38024
HACD2 3-hydroxyacyl-CoA dehydratase 2 -3.26927
FZD1 frizzled class receptor 1 -3.09423
C1ORF131 chromosome 1 open reading frame 131 -2.92493
GLUL glutamate-ammonia ligase -2.91996
ZSWIM7 zinc finger, SWIM-type containing 7 -2.66583
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -2.60784
NR1H2 nuclear receptor subfamily 1, group H, member 2 -2.58248
TLK2 tousled-like kinase 2 -2.54884
TBC1D12 TBC1 domain family, member 12 -2.48202
EIF4A2 eukaryotic translation initiation factor 4A2 -2.47786
ARSA arylsulfatase A -2.47773
TIPRL TOR signaling pathway regulator -2.45848
FAM45A family with sequence similarity 45, member A -2.45398
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.45055
USP22 ubiquitin specific peptidase 22 -2.44747
CDC37L1 cell division cycle 37-like 1 -2.44455
GSTO1 glutathione S-transferase omega 1 -2.423
C17ORF85 chromosome 17 open reading frame 85 -2.40449
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase -2.40185
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -2.39491
GCGR glucagon receptor -2.37973
LYPLA2 lysophospholipase II -2.37911
CCNG2 cyclin G2 -2.35846
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -2.34675
LMBRD1 LMBR1 domain containing 1 -2.32692
SMAP1 small ArfGAP 1 -2.32215
PERP PERP, TP53 apoptosis effector -2.32079
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -2.31678
MTA1 metastasis associated 1 -2.29571
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -2.28724
TPD52L1 tumor protein D52-like 1 -2.27578
JDP2 Jun dimerization protein 2 -2.27474
SRP9 signal recognition particle 9kDa -2.24004
C16ORF13 chromosome 16 open reading frame 13 -2.23608
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -2.22074
POU2F1 POU class 2 homeobox 1 -2.21942
PDHX pyruvate dehydrogenase complex, component X -2.21664
EVA1A eva-1 homolog A (C. elegans) -2.21371
ITFG3 integrin alpha FG-GAP repeat containing 3 -2.20623
TCEAL8 transcription elongation factor A (SII)-like 8 -2.19055
ETNK2 ethanolamine kinase 2 -2.18831
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -2.17728
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 -2.176
HPN hepsin -2.17544
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.16601
IRF2 interferon regulatory factor 2 -2.15029
MIB2 mindbomb E3 ubiquitin protein ligase 2 -2.12907
KLHL17 kelch-like family member 17 -2.11471
TAPBP TAP binding protein (tapasin) -2.1102
DGKA diacylglycerol kinase, alpha 80kDa -2.10602
MANBA mannosidase, beta A, lysosomal -2.07802
WDR33 WD repeat domain 33 -2.078
GTF2IRD1 GTF2I repeat domain containing 1 -2.06877
PARD3 par-3 family cell polarity regulator -2.06655
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa -2.06116
NCAPH2 non-SMC condensin II complex, subunit H2 -2.05198
ERN1 endoplasmic reticulum to nucleus signaling 1 -2.04892
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -2.04638
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase -2.0459
ZBTB22 zinc finger and BTB domain containing 22 -2.03908
CXXC5 CXXC finger protein 5 -2.03867
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -2.03214
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -2.02792
VPS9D1 VPS9 domain containing 1 -2.02239
THOC3 THO complex 3 -2.02136
FAM210B family with sequence similarity 210, member B -2.00254
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -1.99645
ACAD11 acyl-CoA dehydrogenase family, member 11 -1.99529
THAP11 THAP domain containing 11 -1.99457
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 -1.9927
ASCC2 activating signal cointegrator 1 complex subunit 2 -1.97967
ZNF276 zinc finger protein 276 -1.96351
WDR45 WD repeat domain 45 -1.96234
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.95907
RBPMS2 RNA binding protein with multiple splicing 2 -1.95658
HAUS4 HAUS augmin-like complex, subunit 4 -1.95608
PUS10 pseudouridylate synthase 10 -1.95316
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -1.94378
GPBP1L1 GC-rich promoter binding protein 1-like 1 -1.93695
SEPW1 selenoprotein W, 1 -1.93172
CHRAC1 chromatin accessibility complex 1 -1.93025
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -1.92792
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -1.92429
ZNF574 zinc finger protein 574 -1.91812
TMEM180 transmembrane protein 180 -1.91065
CPNE1 copine I -1.90948
MCUR1 mitochondrial calcium uniporter regulator 1 -1.90702
CASZ1 castor zinc finger 1 -1.90194
EIF4H eukaryotic translation initiation factor 4H -1.89983
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -1.88372
MAN1A1 mannosidase, alpha, class 1A, member 1 -1.883
MOBP myelin-associated oligodendrocyte basic protein -1.87325
DUSP23 dual specificity phosphatase 23 -1.86761
YIPF3 Yip1 domain family, member 3 -1.86256
LBR lamin B receptor -1.86142
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -1.86132
DHRS11 dehydrogenase/reductase (SDR family) member 11 -1.85835
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.8512
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -1.84926
SPPL3 signal peptide peptidase like 3 -1.84893
PPP4R2 protein phosphatase 4, regulatory subunit 2 -1.84796
VAMP4 vesicle-associated membrane protein 4 -1.84734
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -1.84521
TEX30 testis expressed 30 -1.84386
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 -1.84376
CERS5 ceramide synthase 5 -1.84325
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -1.84252
SKAP2 src kinase associated phosphoprotein 2 -1.8409
SCGB3A1 secretoglobin, family 3A, member 1 -1.8383
HSF1 heat shock transcription factor 1 -1.82813
ISOC1 isochorismatase domain containing 1 -1.82646
FUNDC1 FUN14 domain containing 1 -1.82614
MARCH5 membrane-associated ring finger (C3HC4) 5 -1.82392
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -1.82262
PRKCI protein kinase C, iota -1.80753
SLC35E3 solute carrier family 35, member E3 -1.80562
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -1.8013
PTDSS2 phosphatidylserine synthase 2 -1.79602
WBP1L WW domain binding protein 1-like -1.79201
FANCA Fanconi anemia, complementation group A -1.79139
SUCLG1 succinate-CoA ligase, alpha subunit -1.79032
SFXN1 sideroflexin 1 -1.78722
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -1.78719
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -1.78378
KCMF1 potassium channel modulatory factor 1 -1.78327
TDO2 tryptophan 2,3-dioxygenase -1.77819
TXNRD2 thioredoxin reductase 2 -1.77734
NLN neurolysin (metallopeptidase M3 family) -1.76318
PXDC1 PX domain containing 1 -1.75589
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) -1.75547
FBXL17 F-box and leucine-rich repeat protein 17 -1.75524
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 -1.7518
MRPL40 mitochondrial ribosomal protein L40 -1.75123
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -1.74773
CTSH cathepsin H -1.74714
CCAR2 cell cycle and apoptosis regulator 2 -1.74576
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -1.74503
TTC21B tetratricopeptide repeat domain 21B -1.74469
MRPL41 mitochondrial ribosomal protein L41 -1.74357
TMEM184B transmembrane protein 184B -1.74156
YPEL5 yippee-like 5 (Drosophila) -1.73926
CCDC23 coiled-coil domain containing 23 -1.73194
PGM2L1 phosphoglucomutase 2-like 1 -1.73086
TMEM135 transmembrane protein 135 -1.73016
C12ORF66 chromosome 12 open reading frame 66 -1.72928
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 -1.72478
BRAP BRCA1 associated protein -1.72221
FAF1 Fas (TNFRSF6) associated factor 1 -1.71958
KLC2 kinesin light chain 2 -1.71714
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) -1.71307
PIAS2 protein inhibitor of activated STAT, 2 -1.71188
FKBP2 FK506 binding protein 2, 13kDa -1.71029
XPOT exportin, tRNA -1.70034
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -1.6985
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) -1.6974
PELO pelota homolog (Drosophila) -1.69678
ATP13A1 ATPase type 13A1 -1.69299
CUL1 cullin 1 -1.69297
BOD1 biorientation of chromosomes in cell division 1 -1.69253
RHOT2 ras homolog family member T2 -1.69003
FBXO7 F-box protein 7 -1.68934
C1QBP complement component 1, q subcomponent binding protein -1.68457
FMO5 flavin containing monooxygenase 5 -1.68332
KIAA2018 KIAA2018 -1.67984
FIZ1 FLT3-interacting zinc finger 1 -1.67906
AADAT aminoadipate aminotransferase -1.67748
BCCIP BRCA2 and CDKN1A interacting protein -1.67748
PEX6 peroxisomal biogenesis factor 6 -1.6722
EMC2 ER membrane protein complex subunit 2 -1.66955
SIN3B SIN3 transcription regulator family member B -1.66936
FXR2 fragile X mental retardation, autosomal homolog 2 -1.66747
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -1.66377
SKP1 S-phase kinase-associated protein 1 -1.66348
TMPRSS6 transmembrane protease, serine 6 -1.66154
MTX2 metaxin 2 -1.65855
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -1.65849
GOT1 glutamic-oxaloacetic transaminase 1, soluble -1.65475
SCYL3 SCY1-like 3 (S. cerevisiae) -1.65359
SMAGP small cell adhesion glycoprotein -1.65302
TMCO3 transmembrane and coiled-coil domains 3 -1.64669
CLCN4 chloride channel, voltage-sensitive 4 -1.64575
TP53INP2 tumor protein p53 inducible nuclear protein 2 -1.64421
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) -1.63818
HLA-A major histocompatibility complex, class I, A -1.63816
DNASE2 deoxyribonuclease II, lysosomal -1.63546
GLB1 galactosidase, beta 1 -1.63289
S100A1 S100 calcium binding protein A1 -1.63188
RCL1 RNA terminal phosphate cyclase-like 1 -1.63174
PMPCB peptidase (mitochondrial processing) beta -1.63058
MACROD1 MACRO domain containing 1 -1.63043
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 -1.62675
GLO1 glyoxalase I -1.62629
KIAA0930 KIAA0930 -1.61369
NT5DC3 5'-nucleotidase domain containing 3 -1.6126
SCO2 SCO2 cytochrome c oxidase assembly protein -1.61157
C16ORF74 chromosome 16 open reading frame 74 -1.61108
FAHD2B fumarylacetoacetate hydrolase domain containing 2B -1.61024
C2CD2 C2 calcium-dependent domain containing 2 -1.60745
TMEM192 transmembrane protein 192 -1.60708
OAF OAF homolog (Drosophila) -1.60267
ASB13 ankyrin repeat and SOCS box containing 13 -1.60169
EBP emopamil binding protein (sterol isomerase) -1.60129
CD82 CD82 molecule -1.60061
MN1 meningioma (disrupted in balanced translocation) 1 -1.60014
AADAC arylacetamide deacetylase -1.59565
ASB8 ankyrin repeat and SOCS box containing 8 -1.59526
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.5945
APOO apolipoprotein O -1.59272
IL24 interleukin 24 -1.58927
ARHGAP23 Rho GTPase activating protein 23 -1.58439
ADIPOR1 adiponectin receptor 1 -1.5815
PCCB propionyl CoA carboxylase, beta polypeptide -1.5793
GLTSCR2 glioma tumor suppressor candidate region gene 2 -1.5788
GJC1 gap junction protein, gamma 1, 45kDa -1.57228
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -1.57206
PFDN6 prefoldin subunit 6 -1.57076
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -1.56912
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -1.56653
SLC38A4 solute carrier family 38, member 4 -1.56461
PON3 paraoxonase 3 -1.56402
TPT1 tumor protein, translationally-controlled 1 -1.55705
NUBPL nucleotide binding protein-like -1.55702
L3MBTL2 l(3)mbt-like 2 (Drosophila) -1.55666
CRBN cereblon -1.55299
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 -1.55111
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -1.55049
PARP6 poly (ADP-ribose) polymerase family, member 6 -1.54705
STARD8 StAR-related lipid transfer (START) domain containing 8 -1.54654
PPA2 pyrophosphatase (inorganic) 2 -1.54499
C2CD3 C2 calcium-dependent domain containing 3 -1.54466
MGP matrix Gla protein -1.54333
C20ORF196 chromosome 20 open reading frame 196 -1.54166
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -1.54097
RRAGC Ras-related GTP binding C -1.54058
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -1.53872
PDE3B phosphodiesterase 3B, cGMP-inhibited -1.53716
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -1.53473
FAM63B family with sequence similarity 63, member B -1.53411
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -1.53384
TSPAN31 tetraspanin 31 -1.53367
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L -1.53082
USP10 ubiquitin specific peptidase 10 -1.53056
VMP1 vacuole membrane protein 1 -1.52995
CBX7 chromobox homolog 7 -1.52624
MYF6 myogenic factor 6 (herculin) -1.52545
FAM212A family with sequence similarity 212, member A -1.52208
PQBP1 polyglutamine binding protein 1 -1.52126
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -1.52063
CHKB choline kinase beta -1.51542
SYNGR2 synaptogyrin 2 -1.51431
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) -1.5137
DPYS dihydropyrimidinase -1.51332
DAO D-amino-acid oxidase -1.51136
CLYBL citrate lyase beta like -1.50717
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -1.50287
SAA2-SAA4 SAA2-SAA4 readthrough -1.49658
RUNDC1 RUN domain containing 1 -1.49468
DOPEY2 dopey family member 2 -1.49211
ACVR2A activin A receptor, type IIA -1.49101
C18ORF8 chromosome 18 open reading frame 8 -1.4903
DDT D-dopachrome tautomerase -1.49003
ISCA1 iron-sulfur cluster assembly 1 -1.48757
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -1.48751
UBXN8 UBX domain protein 8 -1.48611
MIIP migration and invasion inhibitory protein -1.48376
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -1.48279
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -1.4826
CD1D CD1d molecule -1.48168
TM7SF2 transmembrane 7 superfamily member 2 -1.47792
TMBIM6 transmembrane BAX inhibitor motif containing 6 -1.47762
FOSL2 FOS-like antigen 2 -1.47744
AAMP angio-associated, migratory cell protein -1.47731
PLCE1 phospholipase C, epsilon 1 -1.4768
TNNI3 troponin I type 3 (cardiac) -1.47612
FBXW8 F-box and WD repeat domain containing 8 -1.47579
UBAC1 UBA domain containing 1 -1.47513
ZSWIM5 zinc finger, SWIM-type containing 5 -1.47505
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -1.4741
PEX3 peroxisomal biogenesis factor 3 -1.47404
NIPSNAP3A nipsnap homolog 3A (C. elegans) -1.47253
DNHD1 dynein heavy chain domain 1 -1.47222
B3GNT1 -1.46948
STOML2 stomatin (EPB72)-like 2 -1.46768
DZANK1 double zinc ribbon and ankyrin repeat domains 1 -1.46703
ENY2 enhancer of yellow 2 homolog (Drosophila) -1.46535
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -1.4635
TMEM126A transmembrane protein 126A -1.46025
C11ORF24 chromosome 11 open reading frame 24 -1.45971
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -1.45384
PRODH2 proline dehydrogenase (oxidase) 2 -1.45254
HELZ helicase with zinc finger -1.44668
USF2 upstream transcription factor 2, c-fos interacting -1.44667
PHKA2 phosphorylase kinase, alpha 2 (liver) -1.44451
RPL27A ribosomal protein L27a -1.4433
C8ORF4 chromosome 8 open reading frame 4 -1.44216
MAPK1 mitogen-activated protein kinase 1 -1.4402