TRIM27 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description tripartite motif containing 27|This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5987)
External Link http://www.ncbi.nlm.nih.gov/gene/5987
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Genes

179 interacting proteins for TRIM27 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD17A abhydrolase domain containing 17A
ACIN1 apoptotic chromatin condensation inducer 1
ALMS1 Alstrom syndrome protein 1
AMER1 APC membrane recruitment protein 1
AMOTL1 angiomotin like 1
AMOTL2 angiomotin like 2
ANAPC1 anaphase promoting complex subunit 1
ANAPC5 anaphase promoting complex subunit 5
APC adenomatous polyposis coli
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATXN7 ataxin 7
BAG2 BCL2-associated athanogene 2
BAG5 BCL2-associated athanogene 5
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BEGAIN brain-enriched guanylate kinase-associated
BMI1 BMI1 proto-oncogene, polycomb ring finger
C1ORF109 chromosome 1 open reading frame 109
CCDC77 coiled-coil domain containing 77
CCDC88C coiled-coil domain containing 88C
CDC23 cell division cycle 23
CEP192 centrosomal protein 192kDa
CEP295 centrosomal protein 295kDa
CEP57 centrosomal protein 57kDa
CEP72 centrosomal protein 72kDa
CEP85 centrosomal protein 85kDa
CEP89 centrosomal protein 89kDa
CHD4 chromodomain helicase DNA binding protein 4
CHUK conserved helix-loop-helix ubiquitous kinase
CNTROB centrobin, centrosomal BRCA2 interacting protein
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL4B cullin 4B
CUL5 cullin 5
DAXX death-domain associated protein
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DGCR6 DiGeorge syndrome critical region gene 6
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
EID1 EP300 interacting inhibitor of differentiation 1
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF4E eukaryotic translation initiation factor 4E
EPC1 enhancer of polycomb homolog 1 (Drosophila)
ERC1 ELKS/RAB6-interacting/CAST family member 1
ETV6 ets variant 6
FBF1 Fas (TNFRSF6) binding factor 1
FBXL19 F-box and leucine-rich repeat protein 19
FXYD6 FXYD domain containing ion transport regulator 6
GFI1B growth factor independent 1B transcription repressor
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
HDAC1 histone deacetylase 1
HDAC6 histone deacetylase 6
HR hair growth associated
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INADL InaD-like (Drosophila)
IQCB1 IQ motif containing B1
IQCE IQ motif containing E
JOSD1 Josephin domain containing 1
KCTD15 potassium channel tetramerization domain containing 15
KDM1A lysine (K)-specific demethylase 1A
KIF1A kinesin family member 1A
LATS2 large tumor suppressor kinase 2
LZTS2 leucine zipper, putative tumor suppressor 2
MAGEA11 melanoma antigen family A11
MAGED4 melanoma antigen family D4
MAGEF1 melanoma antigen family F1
MAGEL2 melanoma antigen family L2
MBD2 methyl-CpG binding domain protein 2
MBD3 methyl-CpG binding domain protein 3
MBD4 methyl-CpG binding domain protein 4
MCOLN1 mucolipin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED21 mediator complex subunit 21
MIA3 melanoma inhibitory activity family, member 3
MPDZ multiple PDZ domain protein
MPHOSPH9 M-phase phosphoprotein 9
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MVP major vault protein
MYOD1 myogenic differentiation 1
NDE1 nudE neurodevelopment protein 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFYC nuclear transcription factor Y, gamma
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
NINL ninein-like
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH1 notch 1
NOTCH2 notch 2
NUP160 nucleoporin 160kDa
NUP50 nucleoporin 50kDa
OFD1 oral-facial-digital syndrome 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARD3 par-3 family cell polarity regulator
PAX7 paired box 7
PCM1 pericentriolar material 1
PHLDB2 pleckstrin homology-like domain, family B, member 2
PIAS1 protein inhibitor of activated STAT, 1
PIAS2 protein inhibitor of activated STAT, 2
PIAS3 protein inhibitor of activated STAT, 3
PIAS4 protein inhibitor of activated STAT, 4
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PKP4 plakophilin 4
PLAA phospholipase A2-activating protein
PML promyelocytic leukemia
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP1R18 protein phosphatase 1, regulatory subunit 18
PRAM1 PML-RARA regulated adaptor molecule 1
PUF60 poly-U binding splicing factor 60KDa
RASAL2 RAS protein activator like 2
RB1 retinoblastoma 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RNF25 ring finger protein 25
SDCCAG3 serologically defined colon cancer antigen 3
SEC16A SEC16 homolog A (S. cerevisiae)
SF3A1 splicing factor 3a, subunit 1, 120kDa
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SRRM2 serine/arginine repetitive matrix 2
STXBP4 syntaxin binding protein 4
TAL1 T-cell acute lymphocytic leukemia 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBK1 TANK-binding kinase 1
TCHP trichoplein, keratin filament binding
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNRC6B trinucleotide repeat containing 6B
TP53 tumor protein p53
TRAF5 TNF receptor-associated factor 5
TRIM11 tripartite motif containing 11
TRIM21 tripartite motif containing 21
TRIM23 tripartite motif containing 23
TRIM29 tripartite motif containing 29
TRIM31 tripartite motif containing 31
TRIM32 tripartite motif containing 32
TRIM37 tripartite motif containing 37
TRIM43 tripartite motif containing 43
TRIM55 tripartite motif containing 55
TRIM9 tripartite motif containing 9
TUBGCP4 tubulin, gamma complex associated protein 4
TUFT1 tuftelin 1
UBC ubiquitin C
UBD ubiquitin D
UBE2A ubiquitin-conjugating enzyme E2A
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2H ubiquitin-conjugating enzyme E2H
UBE2I ubiquitin-conjugating enzyme E2I
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2N ubiquitin-conjugating enzyme E2N
UBE2O ubiquitin-conjugating enzyme E2O
UBE2T ubiquitin-conjugating enzyme E2T
UBE2U ubiquitin-conjugating enzyme E2U (putative)
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE2Z ubiquitin-conjugating enzyme E2Z
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
USP2 ubiquitin specific peptidase 2
USP47 ubiquitin specific peptidase 47
USP54 ubiquitin specific peptidase 54
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP9X ubiquitin specific peptidase 9, X-linked
ZBTB16 zinc finger and BTB domain containing 16
ZMYM3 zinc finger, MYM-type 3
ZNF417 zinc finger protein 417