TRIM28 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description tripartite motif containing 28|The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10155)
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Genes

338 genes differentially expressed following the TRIM28 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PRB3 proline-rich protein BstNI subfamily 3 3.38454
PRELP proline/arginine-rich end leucine-rich repeat protein 3.38454
TRIM17 tripartite motif containing 17 3.38454
GLUD2 glutamate dehydrogenase 2 3.38454
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 3.38454
CELA3B chymotrypsin-like elastase family, member 3B 3.38454
PON1 paraoxonase 1 3.38454
PCDHB4 protocadherin beta 4 3.38454
FOXA2 forkhead box A2 3.38454
WNT3A wingless-type MMTV integration site family, member 3A 3.38454
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 3.38454
PRICKLE4 prickle homolog 4 (Drosophila) 3.38454
PI15 peptidase inhibitor 15 3.38454
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 3.38454
OASL 2'-5'-oligoadenylate synthetase-like 3.38454
IL12RB1 interleukin 12 receptor, beta 1 3.38454
OVGP1 oviductal glycoprotein 1, 120kDa 3.38454
SBK2 SH3 domain binding kinase family, member 2 3.38454
HRH1 histamine receptor H1 3.38454
COL20A1 collagen, type XX, alpha 1 3.38454
CEMP1 cementum protein 1 3.38454
FGF22 fibroblast growth factor 22 3.38454
RP1L1 retinitis pigmentosa 1-like 1 3.38454
ZNF492 zinc finger protein 492 3.38454
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 3.38454
UNC13C unc-13 homolog C (C. elegans) 3.38454
HIST1H2BI histone cluster 1, H2bi 3.38454
THRSP thyroid hormone responsive 3.38454
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 3.38454
RAPSN receptor-associated protein of the synapse 3.38454
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 3.38454
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 3.38454
RPL3L ribosomal protein L3-like 3.38454
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 3.38454
MS4A18 membrane-spanning 4-domains, subfamily A, member 18 3.38454
RGPD6 RANBP2-like and GRIP domain containing 6 3.38454
LYZL6 lysozyme-like 6 3.38454
PECAM1 platelet/endothelial cell adhesion molecule 1 3.38454
SPINT3 serine peptidase inhibitor, Kunitz type, 3 3.38454
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 3.38454
RIMBP2 RIMS binding protein 2 3.38454
CLEC19A C-type lectin domain family 19, member A 3.38454
C8ORF48 chromosome 8 open reading frame 48 3.38454
CD300A CD300a molecule 3.38454
SIGLEC9 sialic acid binding Ig-like lectin 9 3.38454
ASB14 ankyrin repeat and SOCS box containing 14 3.38454
TUBB1 tubulin, beta 1 class VI 3.38454
DIRAS2 DIRAS family, GTP-binding RAS-like 2 3.38454
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 3.38454
CPB2 carboxypeptidase B2 (plasma) 3.38454
LOC124900192 uncharacterized LOC124900192 3.38454
PNMA8B PNMA family member 8B 3.38454
GOLGA6L7 golgin A6 family like 7 3.38454
CES4A carboxylesterase 4A 3.38454
HAO2 hydroxyacid oxidase 2 (long chain) 3.38454
GBP4 guanylate binding protein 4 3.38454
BGN biglycan 3.38454
EFNB1 ephrin-B1 3.38454
CLDN16 claudin 16 3.38454
ALX3 ALX homeobox 3 3.38454
BATF3 basic leucine zipper transcription factor, ATF-like 3 3.38454
ODAD1 outer dynein arm docking complex subunit 1 3.38454
PWWP3B PWWP domain containing 3B 3.38454
MYOCOS myocilin opposite strand 3.38454
OR56B2 olfactory receptor family 56 subfamily B member 2 3.38454
WASL-DT WASL divergent transcript 3.38454
RPS21-DT RPS21 divergent transcript 3.38454
DUSP13B dual specificity phosphatase 13B 3.38454
LINC02798 long intergenic non-protein coding RNA 2798 3.38454
FNDC11 fibronectin type III domain containing 11 3.38454
ATP5MGL ATP synthase membrane subunit g like 3.38454
TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 3.38454
NTMT2 N-terminal Xaa-Pro-Lys N-methyltransferase 2 3.38454
MINAR2 membrane integral NOTCH2 associated receptor 2 3.38454
ACSL5 acyl-CoA synthetase long-chain family member 5 3.38454
WDR64 WD repeat domain 64 3.38454
TFEC transcription factor EC 3.38454
TLR8 toll-like receptor 8 3.38454
TLR5 toll-like receptor 5 3.38454
C1ORF167 chromosome 1 open reading frame 167 3.38454
STYK1 serine/threonine/tyrosine kinase 1 3.38454
ANXA13 annexin A13 3.38454
LIX1 Lix1 homolog (chicken) 3.38454
CHRD chordin 3.38454
SERTAD4 SERTA domain containing 4 3.38454
TUBA3D tubulin, alpha 3d 3.38454
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 3.38454
SPDYE16 speedy/RINGO cell cycle regulator family member E16 3.38454
GJD4 gap junction protein, delta 4, 40.1kDa 3.38454
ZNF441 zinc finger protein 441 3.38454
ZNF446 zinc finger protein 446 3.38454
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 3.38454
HNF1A HNF1 homeobox A 3.38454
WDR93 WD repeat domain 93 3.38454
PCDHGC3 protocadherin gamma subfamily C, 3 3.38454
NPIPB7 nuclear pore complex interacting protein family, member B7 3.38454
SAMD10 sterile alpha motif domain containing 10 3.38454
IL1R2 interleukin 1 receptor, type II 3.38454
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 3.38454
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 3.38454
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 3.38454
CD177 CD177 molecule 3.38454
CELA2B chymotrypsin-like elastase family, member 2B 3.38454
CIDEC cell death-inducing DFFA-like effector c 3.38454
COL11A2 collagen, type XI, alpha 2 3.38454
PLA2G4E phospholipase A2, group IVE 3.38454
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1 3.38454
CABP7 calcium binding protein 7 3.38454
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 3.38454
NUTM2G NUT family member 2G 3.38454
AOC3 amine oxidase, copper containing 3 3.38454
PSORS1C2 psoriasis susceptibility 1 candidate 2 3.38454
REEP1 receptor accessory protein 1 3.38454
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 3.38454
ADM5 adrenomedullin 5 (putative) 3.38454
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 3.38454
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 3.38454
FGF18 fibroblast growth factor 18 3.38454
USP17L7 ubiquitin specific peptidase 17-like family member 7 3.38454
DAND5 DAN domain family member 5, BMP antagonist 3.38454
FNDC8 fibronectin type III domain containing 8 3.38454
CCL25 chemokine (C-C motif) ligand 25 3.38454
NLRC3 NLR family, CARD domain containing 3 3.38454
SIAH3 siah E3 ubiquitin protein ligase family member 3 3.38454
OR4D1 olfactory receptor, family 4, subfamily D, member 1 3.38454
CALY calcyon neuron-specific vesicular protein 3.38454
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 3.38454
ETV3L ets variant 3-like 3.38454
ALOX12B arachidonate 12-lipoxygenase, 12R type 3.38454
TTC22 tetratricopeptide repeat domain 22 3.38454
ZNF831 zinc finger protein 831 3.38454
PCDH12 protocadherin 12 3.38454
IL19 interleukin 19 3.38454
MUC16 mucin 16, cell surface associated 3.38454
C18ORF63 chromosome 18 open reading frame 63 3.38454
PHOX2A paired-like homeobox 2a 3.38454
ETNPPL ethanolamine-phosphate phospho-lyase 3.38454
TSLP thymic stromal lymphopoietin 3.38454
CTAGE9 CTAGE family, member 9 3.38454
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 3.38454
GOLGA6C golgin A6 family, member C 3.38454
SH2D4B SH2 domain containing 4B 3.38454
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 3.38454
GRAPL GRB2-related adaptor protein-like 3.38454
CRIP2 cysteine-rich protein 2 3.38454
TLDC2 TBC/LysM-associated domain containing 2 3.38454
ADRB2 adrenoceptor beta 2, surface 3.38454
PROM2 prominin 2 3.38454
BTBD16 BTB (POZ) domain containing 16 3.38454
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 3.38454
SMCO1 single-pass membrane protein with coiled-coil domains 1 3.38454
SCIN scinderin 3.38454
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 3.38454
TMEM52B transmembrane protein 52B 3.38454
DNAH2 dynein, axonemal, heavy chain 2 3.38454
PMCH pro-melanin-concentrating hormone 3.38454
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 3.38454
FAM89A family with sequence similarity 89, member A 3.38454
KYNU kynureninase 3.38454
IDUA iduronidase, alpha-L- 3.38454
TAS2R19 taste receptor, type 2, member 19 3.38454
MYO1G myosin IG 3.38454
MRC1 mannose receptor, C type 1 3.38454
BEGAIN brain-enriched guanylate kinase-associated 3.38454
CRYAA crystallin, alpha A 3.38454
OIT3 oncoprotein induced transcript 3 3.38454
PRR22 proline rich 22 3.38454
DCST2 DC-STAMP domain containing 2 3.38454
DKK2 dickkopf WNT signaling pathway inhibitor 2 3.38454
AZU1 azurocidin 1 3.38454
KIF19 kinesin family member 19 3.38454
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 3.38454
TGM6 transglutaminase 6 3.38454
LPO lactoperoxidase 3.38454
NLRP7 NLR family, pyrin domain containing 7 3.38454
FRMPD2 FERM and PDZ domain containing 2 3.38454
LY6G5C lymphocyte antigen 6 complex, locus G5C 3.38454
RASAL1 RAS protein activator like 1 (GAP1 like) 3.33011
ELOVL6 ELOVL fatty acid elongase 6 3.32798
WNT2B wingless-type MMTV integration site family, member 2B 3.29503
CDYL2 chromodomain protein, Y-like 2 3.29503
CEP295 centrosomal protein 295kDa 3.26031
TMEM144 transmembrane protein 144 3.21038
GAL3ST1 galactose-3-O-sulfotransferase 1 3.12112
RELL1 RELT-like 1 3.02989
CNTNAP2 contactin associated protein-like 2 2.90067
PRKCA protein kinase C, alpha 2.88193
FOXP1 forkhead box P1 2.86187
PLA2G15 phospholipase A2, group XV 2.79524
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.7915
ZNF649 zinc finger protein 649 2.77292
TRIM23 tripartite motif containing 23 2.67403
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 2.67403
FOXK2 forkhead box K2 2.59447
NFYC nuclear transcription factor Y, gamma 2.57293
FCHO1 FCH domain only 1 2.56295
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 2.54043
NOTCH2 notch 2 2.53807
SV2A synaptic vesicle glycoprotein 2A 2.51316
CLDN14 claudin 14 2.47203
CBX5 chromobox homolog 5 2.46525
FUNDC2 FUN14 domain containing 2 2.44384
RAP1A RAP1A, member of RAS oncogene family 2.40839
SAC3D1 SAC3 domain containing 1 2.39779
ELOVL1 ELOVL fatty acid elongase 1 2.36379
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 2.3535
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 2.35297
CEACAM19 carcinoembryonic antigen-related cell adhesion molecule 19 2.35034
TMC6 transmembrane channel-like 6 2.31604
TMEM11 transmembrane protein 11 2.31269
GLI1 GLI family zinc finger 1 2.28954
RPA2 replication protein A2, 32kDa 2.28139
ASPHD2 aspartate beta-hydroxylase domain containing 2 2.23023
MEMO1 mediator of cell motility 1 2.21185
LEPROT leptin receptor overlapping transcript 2.19054
ZSCAN2 zinc finger and SCAN domain containing 2 2.14947
PRICKLE2 prickle homolog 2 (Drosophila) 2.12876
RALGDS ral guanine nucleotide dissociation stimulator 2.09084
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2.05559
BANP BTG3 associated nuclear protein 2.0297
PDZD8 PDZ domain containing 8 2.0172
GPNMB glycoprotein (transmembrane) nmb 2.00588

decreased expression

Symbol Name Standardized Value
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -3.38454
MEGF10-DT MEGF10 divergent transcript -3.38454
MTCP1 mature T-cell proliferation 1 -3.38454
KLHL25 kelch-like family member 25 -3.38454
SPDYE5 speedy/RINGO cell cycle regulator family member E5 -3.38454
SLC30A3 solute carrier family 30 (zinc transporter), member 3 -3.38454
DMGDH dimethylglycine dehydrogenase -3.33559
NHP2 NHP2 ribonucleoprotein -3.2905
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -3.28757
DEFB134 defensin, beta 134 -3.26031
CORIN corin, serine peptidase -3.26031
C17ORF100 chromosome 17 open reading frame 100 -3.26031
NLRP2 NLR family, pyrin domain containing 2 -3.26031
LTBP2 latent transforming growth factor beta binding protein 2 -3.26031
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -3.26031
LRRC39 leucine rich repeat containing 39 -3.26031
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -3.26031
BTN3A2 butyrophilin, subfamily 3, member A2 -3.26031
CIITA class II, major histocompatibility complex, transactivator -3.26031
KCNIP2 Kv channel interacting protein 2 -3.26031
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) -3.26031
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 -3.26031
NPIPA2 nuclear pore complex interacting protein family, member A2 -3.26031
HEPHL1 hephaestin-like 1 -3.26031
MRO maestro -3.26031
SLC44A4 solute carrier family 44, member 4 -3.26031
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) -3.26031
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 -3.26031
LIPH lipase, member H -3.26031
UPP2 uridine phosphorylase 2 -3.26031
STARD5 StAR-related lipid transfer (START) domain containing 5 -3.26031
TRIM68 tripartite motif containing 68 -3.26031
TMEM200B transmembrane protein 200B -3.26031
EMILIN1 elastin microfibril interfacer 1 -3.26031
SLC7A14 solute carrier family 7, member 14 -3.26031
VSTM5 V-set and transmembrane domain containing 5 -3.26031
NEIL1 nei endonuclease VIII-like 1 (E. coli) -3.26031
ODAD4 outer dynein arm docking complex subunit 4 -3.26031
GPR68 G protein-coupled receptor 68 -3.26031
ERFE erythroferrone -3.26031
DHFR2 dihydrofolate reductase 2 -3.26031
PNMA8C PNMA family member 8C -3.26031
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -3.26031
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -3.26031
FAM209B family with sequence similarity 209, member B -3.26031
ZNF524 zinc finger protein 524 -3.26031
HKDC1 hexokinase domain containing 1 -3.26031
PEX12 peroxisomal biogenesis factor 12 -3.26031
PRH1-TAS2R14 PRH1-TAS2R14 readthrough -3.26031
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -3.26031
DNAH10 dynein, axonemal, heavy chain 10 -3.26031
DYDC1 DPY30 domain containing 1 -3.26031
CSP2 CS pseudogene 2 -3.26031
SCN7A sodium channel, voltage gated, type VII alpha subunit -3.26031
C1QTNF7 C1q and tumor necrosis factor related protein 7 -3.26031
TNN tenascin N -3.26031
TCF24 transcription factor 24 -3.26031
ACTL6B actin-like 6B -3.26031
MIEF2 mitochondrial elongation factor 2 -3.26031
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -3.19079
UBXN6 UBX domain protein 6 -3.11823
MFAP3 microfibrillar-associated protein 3 -3.10362
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -2.99547
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.99547
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -2.99178
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -2.96896
THAP2 THAP domain containing, apoptosis associated protein 2 -2.88193
RWDD2A RWD domain containing 2A -2.83806
NDC80 NDC80 kinetochore complex component -2.81834
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.80824
FLT4 fms-related tyrosine kinase 4 -2.70383
PNMA6A paraneoplastic Ma antigen family member 6A -2.70383
NPIPA5 nuclear pore complex interacting protein family, member A5 -2.70383
CXCL5 chemokine (C-X-C motif) ligand 5 -2.70383
NOTCH2NLA notch 2 N-terminal like A -2.70383
DPP7 dipeptidyl-peptidase 7 -2.68531
TTI1 TELO2 interacting protein 1 -2.59447
PHF21B PHD finger protein 21B -2.56295
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -2.55226
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.55226
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa -2.51316
ZNF74 zinc finger protein 74 -2.48332
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -2.45971
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit -2.39779
EYS eyes shut homolog (Drosophila) -2.39396
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 -2.39396
UBE2A ubiquitin-conjugating enzyme E2A -2.37611
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -2.37611
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -2.37173
CASC3 cancer susceptibility candidate 3 -2.36464
TMEM51 transmembrane protein 51 -2.36018
GPC2 glypican 2 -2.36018
SDR42E2 short chain dehydrogenase/reductase family 42E, member 2 -2.35649
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.35649
KDF1 keratinocyte differentiation factor 1 -2.35649
PHKG1 phosphorylase kinase, gamma 1 (muscle) -2.35649
GDF3 growth differentiation factor 3 -2.35649
DSC3 desmocollin 3 -2.35649
PTPRN protein tyrosine phosphatase, receptor type, N -2.35649
EIF5A eukaryotic translation initiation factor 5A -2.3172
ELOB elongin B -2.26353
DUSP7 dual specificity phosphatase 7 -2.26341
ZNF469 zinc finger protein 469 -2.26341
FAM135A family with sequence similarity 135, member A -2.24299
CPT2 carnitine palmitoyltransferase 2 -2.22386
BIRC6 baculoviral IAP repeat containing 6 -2.21896
PRR14 proline rich 14 -2.14972
MSMO1 methylsterol monooxygenase 1 -2.12928
NAAA N-acylethanolamine acid amidase -2.12594
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -2.12556
TCF7 transcription factor 7 (T-cell specific, HMG-box) -2.11945
FMO4 flavin containing monooxygenase 4 -2.10502
THOC1 THO complex 1 -2.08837
PLPP6 phospholipid phosphatase 6 -2.04921
HDGFL3 HDGF like 3 -2.02173
RASIP1 Ras interacting protein 1 -2.00588