TRIM36 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description tripartite motif containing 36|The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 55521)
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Genes

330 genes differentially expressed following the TRIM36 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.74561
KPTN kaptin (actin binding protein) 2.74561
CRISP1 cysteine-rich secretory protein 1 2.74561
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 2.74561
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.74561
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.74561
SSMEM1 serine-rich single-pass membrane protein 1 2.74561
TLX2 T-cell leukemia homeobox 2 2.74561
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.74561
RGPD3 RANBP2-like and GRIP domain containing 3 2.74561
PDYN prodynorphin 2.74561
GFRA3 GDNF family receptor alpha 3 2.74561
NR1H4 nuclear receptor subfamily 1, group H, member 4 2.74561
CARD18 caspase recruitment domain family, member 18 2.74561
ADGRE3 adhesion G protein-coupled receptor E3 2.74561
IZUMO3 IZUMO family member 3 2.74561
CD19 CD19 molecule 2.74561
JUNB jun B proto-oncogene 2.74561
TMEM176B transmembrane protein 176B 2.74561
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.74561
CD160 CD160 molecule 2.74561
SHE Src homology 2 domain containing E 2.74561
OR5V1 olfactory receptor, family 5, subfamily V, member 1 2.74561
FGF9 fibroblast growth factor 9 2.74561
BTBD19 BTB (POZ) domain containing 19 2.74561
SMCO2 single-pass membrane protein with coiled-coil domains 2 2.74561
RBP4 retinol binding protein 4, plasma 2.74561
PITX3 paired-like homeodomain 3 2.74561
ICAM5 intercellular adhesion molecule 5, telencephalin 2.74561
STOML3 stomatin (EPB72)-like 3 2.74561
MEIOB meiosis specific with OB domains 2.74561
CLNK cytokine-dependent hematopoietic cell linker 2.74561
LRRC53 leucine rich repeat containing 53 2.74561
NR4A2 nuclear receptor subfamily 4, group A, member 2 2.74561
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 2.74561
ATOH8 atonal homolog 8 (Drosophila) 2.74561
TRPC5OS TRPC5 opposite strand 2.74561
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 2.74561
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.74561
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.74561
HES2 hes family bHLH transcription factor 2 2.74561
TMEM132C transmembrane protein 132C 2.74561
EPHB3 EPH receptor B3 2.74561
TEX35 testis expressed 35 2.74561
NAPSA napsin A aspartic peptidase 2.74561
C3ORF85 chromosome 3 open reading frame 85 2.74561
OR2T8 olfactory receptor, family 2, subfamily T, member 8 2.74561
COL3A1 collagen, type III, alpha 1 2.74561
TMPRSS3 transmembrane protease, serine 3 2.74561
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 2.74561
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.74561
BDKRB1 bradykinin receptor B1 2.74561
SPATA22 spermatogenesis associated 22 2.74561
BHLHE41 basic helix-loop-helix family, member e41 2.74561
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.74561
PNLIPRP1 pancreatic lipase-related protein 1 2.74561
CD300LF CD300 molecule-like family member f 2.74561
SPMIP3 sperm microtubule inner protein 3 2.74561
LOC124904542 uncharacterized LOC124904542 2.74561
H4C14 H4 clustered histone 14 2.74561
SMIM43 small integral membrane protein 43 2.74561
UBE2L5 ubiquitin conjugating enzyme E2 L5 2.74561
CCN5 cellular communication network factor 5 2.74561
H1-2 H1.2 linker histone, cluster member 2.74561
PCDHGA9 protocadherin gamma subfamily A, 9 2.74561
C3AR1 complement component 3a receptor 1 2.74561
GATA6 GATA binding protein 6 2.74561
GDF9 growth differentiation factor 9 2.74561
PCDHA3 protocadherin alpha 3 2.74561
SCRG1 stimulator of chondrogenesis 1 2.74561
RAB41 RAB41, member RAS oncogene family 2.74561
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 2.74561
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.74561
HSFX4 heat shock transcription factor family, X-linked member 4 2.74561
FPR1 formyl peptide receptor 1 2.74561
GJA9 gap junction protein, alpha 9, 59kDa 2.74561
SIX3 SIX homeobox 3 2.74561
MAG myelin associated glycoprotein 2.74561
MEOX1 mesenchyme homeobox 1 2.74561
LRRC71 leucine rich repeat containing 71 2.74561
IL1R1 interleukin 1 receptor, type I 2.74561
UTS2 urotensin 2 2.74561
PIWIL3 piwi-like RNA-mediated gene silencing 3 2.74561
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 2.74561
LEF1 lymphoid enhancer-binding factor 1 2.74561
TMEM19 transmembrane protein 19 2.74561
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.74561
NR1I3 nuclear receptor subfamily 1, group I, member 3 2.74561
SPANXB1 SPANX family, member B1 2.74561
SNTN sentan, cilia apical structure protein 2.74561
SV2C synaptic vesicle glycoprotein 2C 2.74561
BAHCC1 BAH domain and coiled-coil containing 1 2.74561
IFITM5 interferon induced transmembrane protein 5 2.74561
MUC16 mucin 16, cell surface associated 2.74561
C17ORF99 chromosome 17 open reading frame 99 2.74561
MS4A7 membrane-spanning 4-domains, subfamily A, member 7 2.74561
TEKT2 tektin 2 (testicular) 2.74561
SLC22A24 solute carrier family 22, member 24 2.74561
ZNF843 zinc finger protein 843 2.74561
UBTF upstream binding transcription factor, RNA polymerase I 2.74561
DRD2 dopamine receptor D2 2.74561
CLEC4C C-type lectin domain family 4, member C 2.74561
HCRT hypocretin (orexin) neuropeptide precursor 2.74561
KLHL6 kelch-like family member 6 2.74561
AQP3 aquaporin 3 (Gill blood group) 2.74561
LRRIQ3 leucine-rich repeats and IQ motif containing 3 2.74561
TAS2R50 taste receptor, type 2, member 50 2.74561
GOLGA6C golgin A6 family, member C 2.74561
TMEM202 transmembrane protein 202 2.74561
TREH trehalase (brush-border membrane glycoprotein) 2.74561
PAGE4 P antigen family, member 4 (prostate associated) 2.74561
TBX1 T-box 1 2.74561
ITGA10 integrin, alpha 10 2.74561
IL9R interleukin 9 receptor 2.74561
CALY calcyon neuron-specific vesicular protein 2.74561
GSC2 goosecoid homeobox 2 2.74561
IGIP IgA-inducing protein 2.74561
GPR150 G protein-coupled receptor 150 2.74561
GPR142 G protein-coupled receptor 142 2.74561
IL25 interleukin 25 2.74561
OTP orthopedia homeobox 2.74561
CPN2 carboxypeptidase N, polypeptide 2 2.74561
ZPBP zona pellucida binding protein 2.74561
CLEC1A C-type lectin domain family 1, member A 2.74561
CLEC1B C-type lectin domain family 1, member B 2.74561
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 2.74561
EPHA5 EPH receptor A5 2.74561
AMN amnion associated transmembrane protein 2.74561
TPPP2 tubulin polymerization-promoting protein family member 2 2.74561
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.74561
FCRLB Fc receptor-like B 2.74561
SYNGR4 synaptogyrin 4 2.74561
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 2.74561
TRIM7 tripartite motif containing 7 2.74561
DPRX divergent-paired related homeobox 2.74561
CDC20B cell division cycle 20B 2.74561
EDN3 endothelin 3 2.74561
MMP3 matrix metallopeptidase 3 2.74561
RSAD2 radical S-adenosyl methionine domain containing 2 2.74561
PTGDS prostaglandin D2 synthase 21kDa (brain) 2.74561
KAZN kazrin, periplakin interacting protein 2.74561
EPO erythropoietin 2.74561
MORC1 MORC family CW-type zinc finger 1 2.74561
STAB1 stabilin 1 2.74561
EPX eosinophil peroxidase 2.74561
LRRC36 leucine rich repeat containing 36 2.74561
MPZL1 myelin protein zero-like 1 2.74561
POU3F2 POU class 3 homeobox 2 2.74561
PLA2G4E phospholipase A2, group IVE 2.74561
CH25H cholesterol 25-hydroxylase 2.74561
F10 coagulation factor X 2.74561
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 2.74561
DEFB134 defensin, beta 134 2.74561
ZBED6 zinc finger, BED-type containing 6 2.74561
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3 2.74561
TMEM86A transmembrane protein 86A 2.74561
SLC25A44 solute carrier family 25, member 44 2.70603
SCML1 sex comb on midleg-like 1 (Drosophila) 2.67492
LTC4S leukotriene C4 synthase 2.65407
MICALL2 MICAL-like 2 2.65407
TTC21A tetratricopeptide repeat domain 21A 2.65407
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.6496
NLRC4 NLR family, CARD domain containing 4 2.6496
ISM2 isthmin 2 2.6496
AFF3 AF4/FMR2 family, member 3 2.6496
FAHD1 fumarylacetoacetate hydrolase domain containing 1 2.58435
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) 2.54554
PUDP pseudouridine 5'-phosphatase 2.50239
THOC7 THO complex 7 2.49714
FBXO5 F-box protein 5 2.48457
DYDC1 DPY30 domain containing 1 2.48249
PARP10 poly (ADP-ribose) polymerase family, member 10 2.44862
ZNF823 zinc finger protein 823 2.40256
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 2.40256
RPA4 replication protein A4, 30kDa 2.40256
ZFR2 zinc finger RNA binding protein 2 2.35427
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 2.34251
ATF2 activating transcription factor 2 2.34251
C19ORF12 chromosome 19 open reading frame 12 2.34251
FAM76A family with sequence similarity 76, member A 2.33544
RPP21 ribonuclease P/MRP 21kDa subunit 2.27993
CLTB clathrin, light chain B 2.2623
MZB1 marginal zone B and B1 cell-specific protein 2.25684
SPACDR sperm acrosome developmental regulator 2.25684
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.24918
RPP14 ribonuclease P/MRP 14kDa subunit 2.24182
ABI1 abl-interactor 1 2.24182
CDK18 cyclin-dependent kinase 18 2.23681
TXLNA taxilin alpha 2.23673
H2AC13 H2A clustered histone 13 2.22877
LIMS2 LIM and senescent cell antigen-like domains 2 2.20888
ACO1 aconitase 1, soluble 2.20068
PIEZO2 piezo-type mechanosensitive ion channel component 2 2.19409
H3C12 H3 clustered histone 12 2.18334
CD320 CD320 molecule 2.14771
ORC4 origin recognition complex, subunit 4 2.12236
GLE1 GLE1 RNA export mediator 2.1093
CNOT11 CCR4-NOT transcription complex, subunit 11 2.10692
OSBP2 oxysterol binding protein 2 2.08937
CCNJL cyclin J-like 2.08496
ZW10 zw10 kinetochore protein 2.06833
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 2.06833
CCDC28A coiled-coil domain containing 28A 2.06545
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 2.05823
CAPZB capping protein (actin filament) muscle Z-line, beta 2.05823
FMO5 flavin containing monooxygenase 5 2.02941
CCM2L cerebral cavernous malformation 2-like 2.02447
GYPE glycophorin E (MNS blood group) 2.00625
MEAF6 MYST/Esa1-associated factor 6 2.00625
CENPT centromere protein T 2.00086

decreased expression

Symbol Name Standardized Value
NANP N-acetylneuraminic acid phosphatase -2.74561
KIFC2 kinesin family member C2 -2.74561
SPATA2L spermatogenesis associated 2-like -2.74561
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.74561
SAMD1 sterile alpha motif domain containing 1 -2.74561
ZNF572 zinc finger protein 572 -2.74561
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.74561
PCDHGB6 protocadherin gamma subfamily B, 6 -2.74561
JAKMIP1 janus kinase and microtubule interacting protein 1 -2.74561
IRAK2 interleukin-1 receptor-associated kinase 2 -2.74561
MED26 mediator complex subunit 26 -2.74561
HARBI1 harbinger transposase derived 1 -2.74561
IGSF10 immunoglobulin superfamily, member 10 -2.74561
SELENBP1 selenium binding protein 1 -2.74561
COA7 cytochrome c oxidase assembly factor 7 (putative) -2.74561
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -2.74561
ZNF222 zinc finger protein 222 -2.74561
GPX2 glutathione peroxidase 2 -2.74561
DEPDC1 DEP domain containing 1 -2.73807
ICE2 interactor of little elongation complex ELL subunit 2 -2.65699
PRSS22 protease, serine, 22 -2.65407
SYNDIG1L synapse differentiation inducing 1-like -2.65407
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 -2.65407
NLRP10 NLR family, pyrin domain containing 10 -2.65407
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) -2.65407
GPR179 G protein-coupled receptor 179 -2.65407
ZSCAN22 zinc finger and SCAN domain containing 22 -2.65407
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -2.65407
GPRASP1 G protein-coupled receptor associated sorting protein 1 -2.65407
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 -2.65407
LINC02798 long intergenic non-protein coding RNA 2798 -2.65407
INSYN1 inhibitory synaptic factor 1 -2.65407
IQCN IQ motif containing N -2.65407
CHCT1 CHD1 helical C-terminal domain containing 1 -2.65407
LOC107985101 uncharacterized LOC107985101 -2.65407
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -2.65407
IAPP islet amyloid polypeptide -2.65407
BARX1 BARX homeobox 1 -2.65407
GGACT gamma-glutamylamine cyclotransferase -2.65407
ZFP28 ZFP28 zinc finger protein -2.65407
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) -2.65407
OR2A42 olfactory receptor, family 2, subfamily A, member 42 -2.65407
SYT15B synaptotagmin 15B -2.65407
TGM1 transglutaminase 1 -2.65407
LOXHD1 lipoxygenase homology domains 1 -2.65407
ABHD1 abhydrolase domain containing 1 -2.65407
CRYBA4 crystallin, beta A4 -2.65407
KRT17 keratin 17, type I -2.65407
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -2.65407
LMOD3 leiomodin 3 (fetal) -2.65407
SH2D4B SH2 domain containing 4B -2.65407
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa -2.65407
F11 coagulation factor XI -2.65407
WFDC1 WAP four-disulfide core domain 1 -2.65407
HFE hemochromatosis -2.65407
POTEJ POTE ankyrin domain family, member J -2.65407
RAD9B RAD9 homolog B (S. pombe) -2.65407
PLA2G5 phospholipase A2, group V -2.65407
FZD8 frizzled class receptor 8 -2.63931
LRRC51 leucine rich repeat containing 51 -2.63931
FAM151B family with sequence similarity 151, member B -2.6274
TAMALIN trafficking regulator and scaffold protein tamalin -2.58766
DZIP1L DAZ interacting zinc finger protein 1-like -2.57596
CETN2 centrin, EF-hand protein, 2 -2.55908
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 -2.53439
CACTIN cactin, spliceosome C complex subunit -2.51235
ZNF233 zinc finger protein 233 -2.49006
FTCD formimidoyltransferase cyclodeaminase -2.49006
NT5C2 5'-nucleotidase, cytosolic II -2.47446
ZNF829 zinc finger protein 829 -2.39404
DEF8 differentially expressed in FDCP 8 homolog (mouse) -2.38761
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.3626
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -2.35882
BBS10 Bardet-Biedl syndrome 10 -2.34719
EMC4 ER membrane protein complex subunit 4 -2.32911
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -2.31732
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 -2.315
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.31434
IKZF5 IKAROS family zinc finger 5 (Pegasus) -2.31434
STK32B serine/threonine kinase 32B -2.29781
TNNT1 troponin T type 1 (skeletal, slow) -2.28626
ANKDD1A ankyrin repeat and death domain containing 1A -2.28626
KCNT2 potassium channel, sodium activated subfamily T, member 2 -2.27993
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -2.22877
MISO1 mitochondrial inner membrane subdomain organizer 1 -2.2167
FMNL2 formin-like 2 -2.21543
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -2.20068
KIFC1 kinesin family member C1 -2.20068
DGLUCY D-glutamate cyclase -2.19913
FBXO4 F-box protein 4 -2.18334
C5 complement component 5 -2.16859
NICOL1 NELL2 interacting cell ontogeny regulator 1 -2.14771
PGF placental growth factor -2.14771
TBP TATA box binding protein -2.136
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 -2.13577
MBOAT7 membrane bound O-acyltransferase domain containing 7 -2.12235
RGMB repulsive guidance molecule family member b -2.12093
CDC73 cell division cycle 73 -2.11443
NUTM2E NUT family member 2E -2.1093
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.10267
PRDX4 peroxiredoxin 4 -2.095
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -2.07299
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -2.06833
MAP7 microtubule-associated protein 7 -2.06833
ZFP36 ZFP36 ring finger protein -2.06833
TATDN1 TatD DNase domain containing 1 -2.06545
ZSWIM4 zinc finger, SWIM-type containing 4 -2.06349
CDKN2AIP CDKN2A interacting protein -2.05823
CENPA centromere protein A -2.04687
PTPRN protein tyrosine phosphatase, receptor type, N -2.04446
CCNK cyclin K -2.0424
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.03281
ZBED5 zinc finger, BED-type containing 5 -2.0161
DNASE2 deoxyribonuclease II, lysosomal -2.01535
ZNF839 zinc finger protein 839 -2.01535
HAGHL hydroxyacylglutathione hydrolase-like -2.00892
ARL13B ADP-ribosylation factor-like 13B -2.00826
XKR8 XK, Kell blood group complex subunit-related family, member 8 -2.00385
KLF11 Kruppel-like factor 11 -2.00385
ZNG1F Zn regulated GTPase metalloprotein activator 1F -2.00385