TRIMETHOPRIM Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge. (Chemical Entities of Biological Interest Ontology, CHEBI_45924)
External Link https://dgidb.org/results?searchType=drug&searchTerms=TRIMETHOPRIM
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Genes

12 interacting proteins for the TRIMETHOPRIM drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.7644
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.7644
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.326741
MPO myeloperoxidase 0.252057
DHFR dihydrofolate reductase 0.129735
G6PD glucose-6-phosphate dehydrogenase 0.0445555
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.0302123
CBX1 chromobox homolog 1 0.0234628
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.0202339
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.0184948
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.0144386
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.00995711