TROP2 regulatory signaling Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP5300.html
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Genes

45 proteins participating in the TROP2 regulatory signaling pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACVRL1 activin A receptor type II-like 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
CCND1 cyclin D1
CCNE1 cyclin E1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHEK1 checkpoint kinase 1
CLDN1 claudin 1
CLDN7 claudin 7
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
EGFR epidermal growth factor receptor
FN1 fibronectin 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK2 Janus kinase 2
JUN jun proto-oncogene
MDK midkine (neurite growth-promoting factor 2)
MMP13 matrix metallopeptidase 13
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOTCH1 notch 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACK1 receptor for activated C kinase 1
RB1 retinoblastoma 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
TACSTD2 tumor-associated calcium signal transducer 2
TLN1 talin 1
VIM vimentin