TRPC1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description transient receptor potential cation channel, subfamily C, member 1|The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 7220)
External Link https://ncbi.nlm.nih.gov/gene/7220
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Genes

496 genes differentially expressed following the TRPC1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0242064
PHACTR2 phosphatase and actin regulator 2 0.0189428
TXLNA taxilin alpha 0.0177271
TPSAB1 tryptase alpha/beta 1 0.0150158
SOX9 SRY (sex determining region Y)-box 9 0.014568
PMP22 peripheral myelin protein 22 0.0143871
CXCL10 chemokine (C-X-C motif) ligand 10 0.0143839
CXCL9 chemokine (C-X-C motif) ligand 9 0.0138728
DYNLL1 dynein, light chain, LC8-type 1 0.0137445
EGR1 early growth response 1 0.0132354
HSPG2 heparan sulfate proteoglycan 2 0.0130933
MMP2 matrix metallopeptidase 2 0.0128829
RCAN2 regulator of calcineurin 2 0.0127165
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.012621
KCTD14 potassium channel tetramerization domain containing 14 0.0125413
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0122017
CXCL11 chemokine (C-X-C motif) ligand 11 0.0121677
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.0121586
RTN2 reticulon 2 0.0120942
CREB1 cAMP responsive element binding protein 1 0.0120737
CPE carboxypeptidase E 0.0120459
ANKRD10 ankyrin repeat domain 10 0.0119666
PEG10 paternally expressed 10 0.0119333
SLC38A1 solute carrier family 38, member 1 0.0117989
AMOTL2 angiomotin like 2 0.0116859
KRT18 keratin 18, type I 0.0116453
MTCL1 microtubule crosslinking factor 1 0.0116322
ABHD3 abhydrolase domain containing 3 0.0113456
CPB1 carboxypeptidase B1 (tissue) 0.0112344
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.011104
GBP1 guanylate binding protein 1, interferon-inducible 0.0110615
RHOB ras homolog family member B 0.0110599
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.0110193
COL15A1 collagen, type XV, alpha 1 0.0109081
TENT4A terminal nucleotidyltransferase 4A 0.0108432
NXN nucleoredoxin 0.0108308
MAGEA3 melanoma antigen family A3 0.0107894
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.0107631
CCNL2 cyclin L2 0.0106112
AKR1C3 aldo-keto reductase family 1, member C3 0.0104873
MTA1 metastasis associated 1 0.0104727
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.0103963
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.010371
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.0103569
TARS1 threonyl-tRNA synthetase 1 0.0102689
AKAP8 A kinase (PRKA) anchor protein 8 0.0101103
AMIGO2 adhesion molecule with Ig-like domain 2 0.0100569
KRT16 keratin 16, type I 0.0100506
PPL periplakin 0.0100462
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0100092
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00987513
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00981517
NIT1 nitrilase 1 0.00980228
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00975425
EPHA2 EPH receptor A2 0.0096966
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00967803
TYMP thymidine phosphorylase 0.00964761
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0095927
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.00950708
OSBPL10 oxysterol binding protein-like 10 0.00950315
C1QA complement component 1, q subcomponent, A chain 0.00949645
SCGN secretagogin, EF-hand calcium binding protein 0.00949296
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00949223
WSB1 WD repeat and SOCS box containing 1 0.0094522
COL4A5 collagen, type IV, alpha 5 0.00944969
ZEB1 zinc finger E-box binding homeobox 1 0.00944608
SLIT2 slit homolog 2 (Drosophila) 0.00943419
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00942432
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.00941919
RIN2 Ras and Rab interactor 2 0.00935313
TGFB1 transforming growth factor, beta 1 0.00935005
DOCK9 dedicator of cytokinesis 9 0.00934653
PMM2 phosphomannomutase 2 0.0093219
HSPB8 heat shock 22kDa protein 8 0.00931162
SOCS1 suppressor of cytokine signaling 1 0.00929983
CXCL14 chemokine (C-X-C motif) ligand 14 0.00928163
KIF5B kinesin family member 5B 0.00923338
HHEX hematopoietically expressed homeobox 0.00922624
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.0092026
DUSP5 dual specificity phosphatase 5 0.00920194
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.00911112
TCERG1 transcription elongation regulator 1 0.00909941
LPAR2 lysophosphatidic acid receptor 2 0.00907251
RHOBTB3 Rho-related BTB domain containing 3 0.00906508
CKM creatine kinase, muscle 0.00906362
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00906298
EXT1 exostosin glycosyltransferase 1 0.00906159
RAB8A RAB8A, member RAS oncogene family 0.00905591
TGM1 transglutaminase 1 0.00903419
JUNB jun B proto-oncogene 0.00902501
CXCL13 chemokine (C-X-C motif) ligand 13 0.00901981
INHBB inhibin, beta B 0.00901398
CA2 carbonic anhydrase II 0.00900407
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.00897449
FABP4 fatty acid binding protein 4, adipocyte 0.00896056
ADARB1 adenosine deaminase, RNA-specific, B1 0.00894914
TRIO trio Rho guanine nucleotide exchange factor 0.00894299
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00894113
TMEM165 transmembrane protein 165 0.00893723
REC8 REC8 meiotic recombination protein 0.00892927
RGS16 regulator of G-protein signaling 16 0.00892714
TIMP3 TIMP metallopeptidase inhibitor 3 0.00892176
BRD4 bromodomain containing 4 0.00891516
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.0089052
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.00889352
ANGPTL2 angiopoietin-like 2 0.00888171
TYMS thymidylate synthetase 0.00887946
CD320 CD320 molecule 0.00886299
HSPA1A heat shock 70kDa protein 1A 0.00884878
MAN2A1 mannosidase, alpha, class 2A, member 1 0.0088427
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00880745
PRDX2 peroxiredoxin 2 0.00880558
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.00879007
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.00875098
PLXNC1 plexin C1 0.00874277
RRBP1 ribosome binding protein 1 0.0087015
RGS5 regulator of G-protein signaling 5 0.00869343
IGHMBP2 immunoglobulin mu binding protein 2 0.00868351
REEP1 receptor accessory protein 1 0.00866967
PCGF3 polycomb group ring finger 3 0.00866804
PDGFC platelet derived growth factor C 0.00866739
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00865155
MED13 mediator complex subunit 13 0.00863086
MN1 meningioma (disrupted in balanced translocation) 1 0.00859912
CCNA2 cyclin A2 0.00856424
PAPOLA poly(A) polymerase alpha 0.00853447
SPEN spen family transcriptional repressor 0.00851234
CHIC2 cysteine-rich hydrophobic domain 2 0.00851205
ACTC1 actin, alpha, cardiac muscle 1 0.00849907
PLAAT3 phospholipase A and acyltransferase 3 0.00846274
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00846057
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.00845809
PILRB paired immunoglobin-like type 2 receptor beta 0.00843682
SMAD7 SMAD family member 7 0.00839113
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.00833376
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00831583
BMP4 bone morphogenetic protein 4 0.00831177
ACADVL acyl-CoA dehydrogenase, very long chain 0.00826323
NPEPL1 aminopeptidase-like 1 0.00825451
BST2 bone marrow stromal cell antigen 2 0.00822755
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00819178
AURKB aurora kinase B 0.00816628
MEST mesoderm specific transcript 0.00815596
ARMCX3 armadillo repeat containing, X-linked 3 0.00814934
SPATA20 spermatogenesis associated 20 0.00814642
JCHAIN joining chain of multimeric IgA and IgM 0.00813538
C1QB complement component 1, q subcomponent, B chain 0.00813085
BTG2 BTG family, member 2 0.00812412
PLXND1 plexin D1 0.00811927
ELP1 elongator acetyltransferase complex subunit 1 0.00811234
TES testin LIM domain protein 0.00810508
LGALS8 lectin, galactoside-binding, soluble, 8 0.00808092
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00806979
FSTL1 follistatin-like 1 0.00806481
TMEM259 transmembrane protein 259 0.00804646
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00804131
CD70 CD70 molecule 0.00803965
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.00803938
CERK ceramide kinase 0.00803621
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.00802257
WWC3 WWC family member 3 0.00801888
STK25 serine/threonine kinase 25 0.00801606
AIM2 absent in melanoma 2 0.0080057
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00799078
GAB2 GRB2-associated binding protein 2 0.0079562
CDA cytidine deaminase 0.00795203
EXOC7 exocyst complex component 7 0.0079452
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00794453
AKAP17A A kinase (PRKA) anchor protein 17A 0.00793419
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.00791309
FRZB frizzled-related protein 0.00789572
CCL8 chemokine (C-C motif) ligand 8 0.00788226
USP48 ubiquitin specific peptidase 48 0.00787646
PLVAP plasmalemma vesicle associated protein 0.0078523
TRIB3 tribbles pseudokinase 3 0.00784126
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.00782535
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.00782338
MFAP4 microfibrillar-associated protein 4 0.00782107
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.00781213
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.0078032
BTBD3 BTB (POZ) domain containing 3 0.00778613
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00778253
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.00776586
PAX6 paired box 6 0.00776501
ELN elastin 0.00776217
FNDC3B fibronectin type III domain containing 3B 0.00774902
SPANXD SPANX family, member D 0.00771846
P3H2 prolyl 3-hydroxylase 2 0.00771796
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.00771465
PLXNA2 plexin A2 0.0076968
FHL2 four and a half LIM domains 2 0.0076699
CCN2 cellular communication network factor 2 0.00766181
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.00763116
NBPF10 neuroblastoma breakpoint family, member 10 0.00762646
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00761393
NPC1 Niemann-Pick disease, type C1 0.00760005
RND3 Rho family GTPase 3 0.00759223
PROCR protein C receptor, endothelial 0.00755267
MAP7 microtubule-associated protein 7 0.00754604
CDC34 cell division cycle 34 0.00753025
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.00752857
GLS glutaminase 0.00752041
ASXL1 additional sex combs like transcriptional regulator 1 0.0075129
PCP4 Purkinje cell protein 4 0.00749587
PDGFD platelet derived growth factor D 0.00749229
ABAT 4-aminobutyrate aminotransferase 0.00747679
IRS1 insulin receptor substrate 1 0.0074692
PLIN1 perilipin 1 0.00746717
ADCY9 adenylate cyclase 9 0.00746706
FBLN1 fibulin 1 0.00744597
WIZ widely interspaced zinc finger motifs 0.00743899
PLEC plectin 0.00743448
MARCHF6 membrane associated ring-CH-type finger 6 0.0074285
NNT nicotinamide nucleotide transhydrogenase 0.00742708
CCNE1 cyclin E1 0.00740657
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00739759
GOLGA8A golgin A8 family, member A 0.00739449
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00739071
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00738789
WASL Wiskott-Aldrich syndrome-like 0.00732375
TNNC2 troponin C type 2 (fast) 0.00730329
ACKR3 atypical chemokine receptor 3 0.00729571
ICE1 interactor of little elongation complex ELL subunit 1 0.00729523
TNS3 tensin 3 0.00729415
PDLIM7 PDZ and LIM domain 7 (enigma) 0.0072901
DICER1 dicer 1, ribonuclease type III 0.0072806
CCND2 cyclin D2 0.00727439
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.00726701
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.00726241
DSC2 desmocollin 2 0.00726124
GOLM1 golgi membrane protein 1 0.00725085
XAF1 XIAP associated factor 1 0.00723689
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.00723293
H1-0 H1.0 linker histone 0.00721684
RABGGTB Rab geranylgeranyltransferase, beta subunit 0.00721528
MRPS30 mitochondrial ribosomal protein S30 0.00721356
GRK5 G protein-coupled receptor kinase 5 0.00721019
ASPN asporin 0.00720963
RASL12 RAS-like, family 12 0.00720811
PNN pinin, desmosome associated protein 0.00720467
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 0.00717135
ZBTB35 zinc finger and BTB domain containing 35 0.0071684
PGF placental growth factor 0.00716122
ACTN4 actinin, alpha 4 0.00715946
PRKCZ protein kinase C, zeta 0.00715868
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.00715595
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00714758
MCM2 minichromosome maintenance complex component 2 0.00714702

decreased expression

Symbol Name Standardized Value
FABP7 fatty acid binding protein 7, brain -0.0169845
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0166918
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0165722
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.0161562
ADD3 adducin 3 (gamma) -0.0160699
MAL mal, T-cell differentiation protein -0.0159472
COPS7A COP9 signalosome subunit 7A -0.0147295
CSTA cystatin A (stefin A) -0.0144386
XPO7 exportin 7 -0.0143125
NEBL nebulette -0.0137951
S100A8 S100 calcium binding protein A8 -0.0137123
CXCL12 chemokine (C-X-C motif) ligand 12 -0.0136361
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.0134877
CLDN8 claudin 8 -0.0131958
GRB7 growth factor receptor-bound protein 7 -0.0131827
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.0129884
DAXX death-domain associated protein -0.0124138
SELL selectin L -0.0120997
CRELD2 cysteine-rich with EGF-like domains 2 -0.0120883
S100A9 S100 calcium binding protein A9 -0.0120865
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0120811
MLF1 myeloid leukemia factor 1 -0.0120509
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.0118331
PNMA8A PNMA family member 8A -0.0117494
PECR peroxisomal trans-2-enoyl-CoA reductase -0.0117183
BHLHE41 basic helix-loop-helix family, member e41 -0.0117027
RGS10 regulator of G-protein signaling 10 -0.0116806
BCL2A1 BCL2-related protein A1 -0.0115575
MME membrane metallo-endopeptidase -0.0115493
LEFTY1 left-right determination factor 1 -0.0115166
DNTT DNA nucleotidylexotransferase -0.0114863
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.0114503
CD59 CD59 molecule, complement regulatory protein -0.0113863
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -0.0113362
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.0113255
AK4 adenylate kinase 4 -0.0111921
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0111633
FOXG1 forkhead box G1 -0.0109881
ANXA1 annexin A1 -0.0109553
TREM1 triggering receptor expressed on myeloid cells 1 -0.0109549
FGFR3 fibroblast growth factor receptor 3 -0.0109459
KRT13 keratin 13, type I -0.0109453
CTSS cathepsin S -0.0109291
CRYBG1 crystallin beta-gamma domain containing 1 -0.0109192
HLA-DRA major histocompatibility complex, class II, DR alpha -0.0108892
GYPC glycophorin C (Gerbich blood group) -0.0108381
FAR2 fatty acyl CoA reductase 2 -0.0107912
LAMP3 lysosomal-associated membrane protein 3 -0.0107747
LINC00623 long intergenic non-protein coding RNA 623 -0.0107654
AZIN1 antizyme inhibitor 1 -0.0106907
IL7R interleukin 7 receptor -0.010636
PADI2 peptidyl arginine deiminase, type II -0.0105957
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.0105799
C1ORF54 chromosome 1 open reading frame 54 -0.0105512
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.0105404
SRPX2 sushi-repeat containing protein, X-linked 2 -0.010491
ACTA2 actin, alpha 2, smooth muscle, aorta -0.0104652
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0103584
TSPYL5 TSPY-like 5 -0.0103113
GPM6B glycoprotein M6B -0.0102425
SLC44A4 solute carrier family 44, member 4 -0.0101289
PRKCA protein kinase C, alpha -0.0101203
AQP9 aquaporin 9 -0.00999705
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00985445
MFAP3L microfibrillar-associated protein 3-like -0.00985329
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.00972095
GRAMD1C GRAM domain containing 1C -0.00971878
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00971373
MMP12 matrix metallopeptidase 12 -0.00971336
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00970092
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00969849
CALB1 calbindin 1, 28kDa -0.00967378
CD1E CD1e molecule -0.00965527
NKX2-1 NK2 homeobox 1 -0.00962622
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00961696
ARL3 ADP-ribosylation factor-like 3 -0.00960995
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00960018
ASRGL1 asparaginase like 1 -0.00950751
BAMBI BMP and activin membrane-bound inhibitor -0.00950145
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00948473
FAM107A family with sequence similarity 107, member A -0.00948356
TYRP1 tyrosinase-related protein 1 -0.00948088
ALCAM activated leukocyte cell adhesion molecule -0.00947953
PLP1 proteolipid protein 1 -0.0094702
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00946095
ZIC1 Zic family member 1 -0.00944542
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00943379
PEBP1 phosphatidylethanolamine binding protein 1 -0.00941948
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00941781
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00940528
GREB1 growth regulation by estrogen in breast cancer 1 -0.00939357
NMRK1 nicotinamide riboside kinase 1 -0.00938795
FBXO11 F-box protein 11 -0.00937004
GLDC glycine dehydrogenase (decarboxylating) -0.00936233
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -0.00933599
C8ORF4 chromosome 8 open reading frame 4 -0.00932551
PDE4B phosphodiesterase 4B, cAMP-specific -0.00926625
DDIT4 DNA-damage-inducible transcript 4 -0.00921777
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00920699
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 -0.0091992
EMX2 empty spiracles homeobox 2 -0.00916108
AQP3 aquaporin 3 (Gill blood group) -0.00915735
DAZAP2 DAZ associated protein 2 -0.00914013
LPXN leupaxin -0.00909989
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00905951
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00905387
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00904551
CD52 CD52 molecule -0.0089657
MAP9 microtubule-associated protein 9 -0.00895123
SIRT5 sirtuin 5 -0.00890286
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -0.00889819
VCAN versican -0.00888856
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.0088519
MT1X metallothionein 1X -0.00885054
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.00884575
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 -0.00884556
TSPAN31 tetraspanin 31 -0.00884274
AOC1 amine oxidase, copper containing 1 -0.00881465
NRN1 neuritin 1 -0.00878408
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00878178
DEFB1 defensin, beta 1 -0.00877067
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -0.00876642
CLEC11A C-type lectin domain family 11, member A -0.00875346
FXYD2 FXYD domain containing ion transport regulator 2 -0.00874204
ZNF226 zinc finger protein 226 -0.00873861
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00873379
YPEL5 yippee-like 5 (Drosophila) -0.00873028
UMOD uromodulin -0.00872304
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -0.00871679
GPR137B G protein-coupled receptor 137B -0.00870082
EPCAM epithelial cell adhesion molecule -0.00869857
DOK5 docking protein 5 -0.00869333
IL2RG interleukin 2 receptor, gamma -0.00867725
SOSTDC1 sclerostin domain containing 1 -0.00866443
AGTR1 angiotensin II receptor, type 1 -0.00862501
C5AR1 complement component 5a receptor 1 -0.00860017
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.00859861
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00859642
AK5 adenylate kinase 5 -0.00855867
HMGA1 high mobility group AT-hook 1 -0.00854718
CD1B CD1b molecule -0.00853367
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00852014
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -0.00850369
SPA17 sperm autoantigenic protein 17 -0.00845012
CYBA cytochrome b-245, alpha polypeptide -0.00843532
NME5 NME/NM23 family member 5 -0.00843269
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.00842326
LCK LCK proto-oncogene, Src family tyrosine kinase -0.0083717
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00836712
GSTO1 glutathione S-transferase omega 1 -0.00833007
PTGES prostaglandin E synthase -0.00829831
SH3YL1 SH3 and SYLF domain containing 1 -0.00829384
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -0.00828864
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) -0.00828314
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00821496
KYNU kynureninase -0.00821467
CD9 CD9 molecule -0.00820049
AMACR alpha-methylacyl-CoA racemase -0.00819433
BMP7 bone morphogenetic protein 7 -0.00817632
UGP2 UDP-glucose pyrophosphorylase 2 -0.00814116
ARHGAP6 Rho GTPase activating protein 6 -0.00813923
PSAP prosaposin -0.00813663
PRKCQ protein kinase C, theta -0.00811571
RCAN1 regulator of calcineurin 1 -0.00810885
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.00807806
MRPS16 mitochondrial ribosomal protein S16 -0.00806659
CLDN10 claudin 10 -0.00803707
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00802434
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.0079988
PRPF4 pre-mRNA processing factor 4 -0.00799838
RPS14P3 ribosomal protein S14 pseudogene 3 -0.00798387
PDZK1 PDZ domain containing 1 -0.00797598
PAMR1 peptidase domain containing associated with muscle regeneration 1 -0.00797531
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.0079645
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 -0.00794331
CD3E CD3e molecule, epsilon (CD3-TCR complex) -0.00793808
RAB31 RAB31, member RAS oncogene family -0.00793735
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00793337
SLC16A4 solute carrier family 16, member 4 -0.00793233
GSTZ1 glutathione S-transferase zeta 1 -0.00792935
ITM2C integral membrane protein 2C -0.00792823
SALL1 spalt-like transcription factor 1 -0.007895
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -0.00788622
LCN2 lipocalin 2 -0.00788224
RPP40 ribonuclease P/MRP 40kDa subunit -0.00785647
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.00784808
EMP2 epithelial membrane protein 2 -0.00784476
TSPAN1 tetraspanin 1 -0.00784086
HHLA3 HERV-H LTR-associating 3 -0.00782602
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00779402
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00779375
CTSK cathepsin K -0.0077665
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.00776202
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00774067
SPRR3 small proline-rich protein 3 -0.00773855
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -0.00773487
PMP2 peripheral myelin protein 2 -0.00771556
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.0077086
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.00769609
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -0.00766856
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.0076668
GPNMB glycoprotein (transmembrane) nmb -0.00765924
FOLR1 folate receptor 1 (adult) -0.00763401
GPR183 G protein-coupled receptor 183 -0.00762127
CYRIA CYFIP related Rac1 interactor A -0.00762118
AHCY adenosylhomocysteinase -0.00761758
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00758738
PTHLH parathyroid hormone-like hormone -0.00758011
LTA4H leukotriene A4 hydrolase -0.00757934
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.00757898
TMEM38B transmembrane protein 38B -0.00757294
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00756376
RAP1B RAP1B, member of RAS oncogene family -0.00756073
ZNF204P zinc finger protein 204, pseudogene -0.00755909
CSRP2 cysteine and glycine-rich protein 2 -0.00755623
TFPI2 tissue factor pathway inhibitor 2 -0.0075496
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.00754758
GRIA1 glutamate receptor, ionotropic, AMPA 1 -0.00754132
TAGLN2 transgelin 2 -0.00752369
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 -0.00750535
ACAT2 acetyl-CoA acetyltransferase 2 -0.00750027
SELENOW selenoprotein W -0.00746507
CETN2 centrin, EF-hand protein, 2 -0.007463
PLK1 polo-like kinase 1 -0.00743002
SMAGP small cell adhesion glycoprotein -0.00742925
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00741126
TFF1 trefoil factor 1 -0.00740046
SRPX sushi-repeat containing protein, X-linked -0.00737803
C6ORF48 chromosome 6 open reading frame 48 -0.00737117
LITAF lipopolysaccharide-induced TNF factor -0.00736241
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.00736237
FGF2 fibroblast growth factor 2 (basic) -0.00735439
TMEM231 transmembrane protein 231 -0.00734686
KRT5 keratin 5, type II -0.00734408
LY86 lymphocyte antigen 86 -0.00734357
ESD esterase D -0.0073411
SAP18 Sin3A-associated protein, 18kDa -0.00733574
KIAA0100 KIAA0100 -0.00733385
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00732994
FBP1 fructose-1,6-bisphosphatase 1 -0.00730997
MRPS18B mitochondrial ribosomal protein S18B -0.00730556
NTS neurotensin -0.00729558
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00729107
TUBB2A tubulin, beta 2A class IIa -0.00728584
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -0.0072853
FAIM Fas apoptotic inhibitory molecule -0.0072153
KNG1 kininogen 1 -0.00721077
BST1 bone marrow stromal cell antigen 1 -0.00720028