| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | transient receptor potential cation channel, subfamily M, member 6|This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Apr 2010] (NCBI Entrez Gene Database, 140803) |
| External Link | https://ncbi.nlm.nih.gov/gene/140803 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the TRPM6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | 0.0286015 |
| CCN2 | cellular communication network factor 2 | 0.0137387 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.0131739 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.0128652 |
| NVL | nuclear VCP-like | 0.0113324 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0108069 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0104341 |
| CD9 | CD9 molecule | 0.0104332 |
| ECM1 | extracellular matrix protein 1 | 0.0103558 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0103536 |
| LTF | lactotransferrin | 0.0102914 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00993633 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00988153 |
| NOP56 | NOP56 ribonucleoprotein | 0.00987613 |
| TFF1 | trefoil factor 1 | 0.00945635 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00912496 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00907323 |
| TPM2 | tropomyosin 2 (beta) | 0.00906582 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00894889 |
| COMP | cartilage oligomeric matrix protein | 0.00889305 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00863911 |
| CDC20 | cell division cycle 20 | 0.00854466 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00849136 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00837812 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.00835751 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00820094 |
| TSPAN8 | tetraspanin 8 | 0.00806341 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00802321 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.00800349 |
| EGR1 | early growth response 1 | 0.00799427 |
| GPX1 | glutathione peroxidase 1 | 0.00794637 |
| COG7 | component of oligomeric golgi complex 7 | 0.00793191 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00792687 |
| RRAD | Ras-related associated with diabetes | 0.00791929 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00789928 |
| AXL | AXL receptor tyrosine kinase | 0.00775233 |
| PANK2 | pantothenate kinase 2 | 0.00771002 |
| FOSL1 | FOS-like antigen 1 | 0.00769514 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00767358 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00764135 |
| FERMT1 | fermitin family member 1 | 0.00762864 |
| TMEM230 | transmembrane protein 230 | 0.00755634 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00753415 |
| ADM | adrenomedullin | 0.00750569 |
| ATF4 | activating transcription factor 4 | 0.00745142 |
| MALL | mal, T-cell differentiation protein-like | 0.00744029 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0074326 |
| DNTT | DNA nucleotidylexotransferase | 0.00740286 |
| SLC16A4 | solute carrier family 16, member 4 | 0.00739416 |
| NOP53 | NOP53 ribosome biogenesis factor | 0.00735073 |
| VPREB1 | pre-B lymphocyte 1 | 0.00732288 |
| ODC1 | ornithine decarboxylase 1 | 0.00731879 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00726568 |
| INHBA | inhibin, beta A | 0.00725883 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00724858 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | 0.00724608 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00722817 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00719783 |
| LYRM4 | LYR motif containing 4 | 0.00709272 |
| ADIRF | adipogenesis regulatory factor | 0.00708866 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.00705082 |
| TEX10 | testis expressed 10 | 0.00703085 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00702635 |
| EPCAM | epithelial cell adhesion molecule | 0.00699969 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 0.00692978 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00687642 |
| SMAD3 | SMAD family member 3 | 0.00682519 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0067914 |
| MAL | mal, T-cell differentiation protein | 0.00677528 |
| ATP9A | ATPase, class II, type 9A | 0.00674877 |
| EZR | ezrin | 0.0067393 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00670228 |
| PYGB | phosphorylase, glycogen; brain | 0.00668385 |
| POPDC3 | popeye domain containing 3 | 0.00667297 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.00665857 |
| PLIN3 | perilipin 3 | 0.00663812 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00662096 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00658217 |
| EFNA1 | ephrin-A1 | 0.00655179 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00655 |
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.00654706 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00649716 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00649505 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.00649142 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00649082 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0064744 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00646773 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00645435 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.006448 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00641767 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00641352 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00639558 |
| ZW10 | zw10 kinetochore protein | 0.00639428 |
| TRIM22 | tripartite motif containing 22 | 0.00639324 |
| TSPAN1 | tetraspanin 1 | 0.00636738 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00636017 |
| HLA-B | major histocompatibility complex, class I, B | 0.00635288 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00632752 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.00631511 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00631097 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00630773 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00628627 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.00628222 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00625832 |
| DIPK1A | divergent protein kinase domain 1A | 0.00624635 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00623184 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.0062313 |
| AGR2 | anterior gradient 2 | 0.00621667 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0062067 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.00620163 |
| L1TD1 | LINE-1 type transposase domain containing 1 | 0.00619786 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00618652 |
| TKTL1 | transketolase-like 1 | 0.00617668 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 0.00616005 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00614785 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00609344 |
| CDC123 | cell division cycle 123 | 0.00607705 |
| RAB3B | RAB3B, member RAS oncogene family | 0.00607337 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00606702 |
| RCAN1 | regulator of calcineurin 1 | 0.00605676 |
| JAM3 | junctional adhesion molecule 3 | 0.00605375 |
| EDF1 | endothelial differentiation-related factor 1 | 0.0060221 |
| RPL14 | ribosomal protein L14 | 0.00600404 |
| HMGA1 | high mobility group AT-hook 1 | 0.00597424 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00588918 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00586727 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00585426 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00584966 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 | 0.0058412 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00580647 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.00580169 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00580053 |
| ASRGL1 | asparaginase like 1 | 0.00578981 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00577898 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00576436 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.00576381 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.00575496 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00573363 |
| OGA | O-GlcNAcase | 0.00571041 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.00569531 |
| BMP2 | bone morphogenetic protein 2 | 0.00569446 |
| CHEK1 | checkpoint kinase 1 | 0.00567679 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00567189 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00566797 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00563367 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | 0.00562526 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00561043 |
| TMEM243 | transmembrane protein 243, mitochondrial | 0.00560065 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | 0.00558352 |
| MEF2A | myocyte enhancer factor 2A | 0.00554393 |
| SFTPD | surfactant protein D | 0.00553485 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00552223 |
| FBL | fibrillarin | 0.00551739 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00550447 |
| CTBP2 | C-terminal binding protein 2 | 0.00548032 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00547752 |
| GPI | glucose-6-phosphate isomerase | 0.00547156 |
| NXT1 | nuclear transport factor 2-like export factor 1 | 0.00547048 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00545585 |
| DUSP1 | dual specificity phosphatase 1 | 0.00545426 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.00545351 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.00543929 |
| H1-10 | H1.10 linker histone | 0.00543752 |
| OVOL2 | ovo-like zinc finger 2 | 0.00543651 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.0054168 |
| SIK1 | salt-inducible kinase 1 | 0.0053859 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00538576 |
| GPX4 | glutathione peroxidase 4 | 0.00537367 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00537353 |
| GFER | growth factor, augmenter of liver regeneration | 0.00536961 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.00535509 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.00535484 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00534326 |
| EDN1 | endothelin 1 | 0.00534011 |
| RRBP1 | ribosome binding protein 1 | 0.00531975 |
| MVP | major vault protein | 0.00531464 |
| MSLN | mesothelin | 0.00530915 |
| TMEM131L | transmembrane 131 like | 0.00530053 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00529983 |
| MKKS | McKusick-Kaufman syndrome | 0.00528717 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00527991 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.00526251 |
| PLCB4 | phospholipase C, beta 4 | 0.00526189 |
| NANOG | Nanog homeobox | 0.00525616 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00524515 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.00522939 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00522231 |
| CRYAB | crystallin, alpha B | 0.00521846 |
| AUTS2 | autism susceptibility candidate 2 | 0.00521394 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | 0.0052128 |
| ITGA6 | integrin, alpha 6 | 0.00519732 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00519668 |
| RPS5 | ribosomal protein S5 | 0.00518622 |
| PARN | poly(A)-specific ribonuclease | 0.00518568 |
| CSNK2A1 | casein kinase 2, alpha 1 polypeptide | 0.00516185 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00516181 |
| UFSP2 | UFM1-specific peptidase 2 | 0.00515481 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00514709 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00514565 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00512857 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.00512601 |
| JUP | junction plakoglobin | 0.00512466 |
| SLIRP | SRA stem-loop interacting RNA binding protein | 0.00511961 |
| NKX2-1 | NK2 homeobox 1 | 0.00511751 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | 0.00510133 |
| EAF2 | ELL associated factor 2 | 0.0050957 |
| PHB | prohibitin | 0.00509335 |
| CAVIN1 | caveolae associated protein 1 | 0.00508223 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00507769 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00507218 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.00506413 |
| NRG1 | neuregulin 1 | 0.00506257 |
| HOXB7 | homeobox B7 | 0.00506149 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 0.00505729 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00504937 |
| SMAGP | small cell adhesion glycoprotein | 0.00504837 |
| CHMP1B | charged multivesicular body protein 1B | 0.00503551 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00503245 |
| FZD7 | frizzled class receptor 7 | 0.00502958 |
| MT1G | metallothionein 1G | 0.00502604 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | 0.00502314 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00501453 |
| RTCB | RNA 2',3'-cyclic phosphate and 5'-OH ligase | 0.00501361 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.00501249 |
| RPS9 | ribosomal protein S9 | 0.00500065 |
| AGPS | alkylglycerone phosphate synthase | 0.00500025 |
| DDRGK1 | DDRGK domain containing 1 | 0.00500011 |
| THBS2 | thrombospondin 2 | 0.00497174 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00495294 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.00495131 |
| VIL1 | villin 1 | 0.00495085 |
| H1-2 | H1.2 linker histone, cluster member | 0.00494745 |
| MICA | MHC class I polypeptide-related sequence A | 0.00494346 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 | 0.00493442 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00491751 |
| GATA6 | GATA binding protein 6 | 0.00491577 |
| SAV1 | salvador family WW domain containing protein 1 | 0.00491297 |
| ANXA3 | annexin A3 | 0.00490305 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00490104 |
| DSTN | destrin (actin depolymerizing factor) | 0.00488421 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00488034 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | 0.0048757 |
| NANS | N-acetylneuraminic acid synthase | 0.00486793 |
| OLFML3 | olfactomedin-like 3 | 0.00485482 |
| SMOX | spermine oxidase | 0.00482401 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.00482175 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00482175 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00482139 |
| LAS1L | LAS1-like (S. cerevisiae) | 0.00480035 |
| ELANE | elastase, neutrophil expressed | 0.0047782 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0142895 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0123906 |
| GNAS | GNAS complex locus | -0.0119739 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0115738 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.011237 |
| PCP4 | Purkinje cell protein 4 | -0.0108727 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.0106719 |
| RTN2 | reticulon 2 | -0.0104376 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0104045 |
| METTL7A | methyltransferase like 7A | -0.0103017 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0101959 |
| S100A2 | S100 calcium binding protein A2 | -0.0101756 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.0101181 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00998761 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00968033 |
| PEG10 | paternally expressed 10 | -0.00958827 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00957039 |
| WT1 | Wilms tumor 1 | -0.00947891 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00930264 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.009139 |
| PLTP | phospholipid transfer protein | -0.00913706 |
| HNMT | histamine N-methyltransferase | -0.00909494 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00907475 |
| CPE | carboxypeptidase E | -0.00902148 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00893668 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00892651 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00879226 |
| TNC | tenascin C | -0.00879196 |
| PEG3 | paternally expressed 3 | -0.00875314 |
| PLXNC1 | plexin C1 | -0.00872254 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00868346 |
| S100A8 | S100 calcium binding protein A8 | -0.0086335 |
| ELOVL2 | ELOVL fatty acid elongase 2 | -0.00862173 |
| ALB | albumin | -0.00861784 |
| TES | testin LIM domain protein | -0.00848111 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00843572 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00842876 |
| CLU | clusterin | -0.00838356 |
| AIF1 | allograft inflammatory factor 1 | -0.0083832 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00833086 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00827233 |
| TMEM176A | transmembrane protein 176A | -0.00818499 |
| OBSL1 | obscurin-like 1 | -0.00814365 |
| MEIS2 | Meis homeobox 2 | -0.00813176 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00810123 |
| TMEM45A | transmembrane protein 45A | -0.00807985 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00807934 |
| TMEM176B | transmembrane protein 176B | -0.00806309 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00804677 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00798411 |
| TSPYL5 | TSPY-like 5 | -0.00796749 |
| KRT23 | keratin 23, type I | -0.00787298 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00777813 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | -0.00777469 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00771082 |
| HOPX | HOP homeobox | -0.00768194 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00763378 |
| CD302 | CD302 molecule | -0.00758834 |
| TARP | TCR gamma alternate reading frame protein | -0.0075557 |
| PRKCB | protein kinase C, beta | -0.00752357 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0075152 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00750233 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00744636 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00742907 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00740787 |
| IFNGR1 | interferon gamma receptor 1 | -0.0074043 |
| SNX10 | sorting nexin 10 | -0.00739655 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00736517 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00735307 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00734353 |
| TSPAN5 | tetraspanin 5 | -0.00732223 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00725213 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.00724318 |
| NOTCH2 | notch 2 | -0.00724276 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00718962 |
| SNAI2 | snail family zinc finger 2 | -0.00717065 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00715862 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.00715268 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00714514 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00714375 |
| C1R | complement component 1, r subcomponent | -0.00712027 |
| CD84 | CD84 molecule | -0.00709135 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00708274 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00708157 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00706662 |
| MCOLN1 | mucolipin 1 | -0.00705967 |
| TMEM106B | transmembrane protein 106B | -0.00705197 |
| SELL | selectin L | -0.00703797 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00703694 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00702716 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00701815 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.006994 |
| PANK3 | pantothenate kinase 3 | -0.00699089 |
| COMT | catechol-O-methyltransferase | -0.00694981 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00691945 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00677664 |
| KRT1 | keratin 1, type II | -0.00676475 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00673458 |
| C4BPB | complement component 4 binding protein, beta | -0.00671354 |
| CHN1 | chimerin 1 | -0.00671115 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00670274 |
| MMP7 | matrix metallopeptidase 7 | -0.00668658 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00667816 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00666123 |
| FAM3C | family with sequence similarity 3, member C | -0.00658821 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.0065605 |
| NCKAP1 | NCK-associated protein 1 | -0.00653656 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.0065169 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00650625 |
| S100A9 | S100 calcium binding protein A9 | -0.00650159 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | -0.0064346 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00640021 |
| WSB2 | WD repeat and SOCS box containing 2 | -0.00638971 |
| RBL2 | retinoblastoma-like 2 | -0.00636959 |
| MT3 | metallothionein 3 | -0.00628298 |
| NDRG2 | NDRG family member 2 | -0.00628157 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00622253 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00617937 |
| KYNU | kynureninase | -0.00617909 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00615441 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00613186 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0061176 |
| DCLK1 | doublecortin-like kinase 1 | -0.00610543 |
| OLFM1 | olfactomedin 1 | -0.0061002 |
| TMEM165 | transmembrane protein 165 | -0.00608837 |
| DCP2 | decapping mRNA 2 | -0.00608047 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00607987 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00607323 |
| MPZL2 | myelin protein zero-like 2 | -0.00606272 |
| PPL | periplakin | -0.00606034 |
| FGL2 | fibrinogen-like 2 | -0.00605519 |
| KIF1A | kinesin family member 1A | -0.00605005 |
| ABHD3 | abhydrolase domain containing 3 | -0.0060459 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00604251 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | -0.00602136 |
| PRDX2 | peroxiredoxin 2 | -0.00601998 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00601833 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.0060158 |
| ACP2 | acid phosphatase 2, lysosomal | -0.00601512 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00601067 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00598247 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00596487 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00596436 |
| C1ORF174 | chromosome 1 open reading frame 174 | -0.00595309 |
| CCR1 | chemokine (C-C motif) receptor 1 | -0.0059465 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00593823 |
| ACYP2 | acylphosphatase 2, muscle type | -0.00592678 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00592674 |
| WWC3 | WWC family member 3 | -0.00591512 |
| MANSC1 | MANSC domain containing 1 | -0.00589855 |
| CD300A | CD300a molecule | -0.00589602 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0058793 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00587073 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00585272 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00585091 |
| CBX6 | chromobox homolog 6 | -0.00584644 |
| NELL2 | NEL-like 2 (chicken) | -0.005841 |
| PCDH17 | protocadherin 17 | -0.00581398 |
| S100A7 | S100 calcium binding protein A7 | -0.00581364 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00580962 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.00580738 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00579637 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00578875 |
| KAT2B | K(lysine) acetyltransferase 2B | -0.00578707 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00576121 |
| KLHDC10 | kelch domain containing 10 | -0.00574831 |
| SDC2 | syndecan 2 | -0.00573892 |
| ABLIM1 | actin binding LIM protein 1 | -0.00573566 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00572563 |
| SLC35E2B | solute carrier family 35, member E2B | -0.00571807 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00571579 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00571421 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.00570908 |
| GPR87 | G protein-coupled receptor 87 | -0.0057079 |
| FAM172A | family with sequence similarity 172, member A | -0.00570624 |
| FRY | furry homolog (Drosophila) | -0.00569656 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00568221 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00565487 |
| CD163 | CD163 molecule | -0.00564369 |
| CKAP2 | cytoskeleton associated protein 2 | -0.00563824 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.00563416 |
| DMXL2 | Dmx-like 2 | -0.00562454 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00561321 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.0056053 |
| DGKZ | diacylglycerol kinase, zeta | -0.00559675 |
| GOLGA8A | golgin A8 family, member A | -0.00558949 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | -0.00556987 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00555358 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00554466 |
| TGOLN2 | trans-golgi network protein 2 | -0.00552577 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00552092 |
| ANK2 | ankyrin 2, neuronal | -0.00551976 |
| DPY19L4 | dpy-19-like 4 (C. elegans) | -0.00551728 |
| SDC3 | syndecan 3 | -0.00551347 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00550774 |
| SNX7 | sorting nexin 7 | -0.00550472 |
| SARAF | store-operated calcium entry-associated regulatory factor | -0.00549187 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00548976 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0054735 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00546932 |
| PLEK | pleckstrin | -0.00546675 |
| STMN2 | stathmin 2 | -0.0054524 |
| MYBPC1 | myosin binding protein C, slow type | -0.00544792 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0054475 |
| XIC | X chromosome inactivation center | -0.00543684 |
| FZD6 | frizzled class receptor 6 | -0.00543454 |
| C5ORF28 | chromosome 5 open reading frame 28 | -0.00543147 |
| NIT1 | nitrilase 1 | -0.00541729 |
| IL2RB | interleukin 2 receptor, beta | -0.00540487 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00540187 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00538069 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00536879 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.00536453 |
| RTN1 | reticulon 1 | -0.00535174 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | -0.00533864 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00533429 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00533129 |
| PTN | pleiotrophin | -0.0053307 |
| SHOX2 | short stature homeobox 2 | -0.0053173 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00530908 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00529266 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00527978 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00527863 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00527821 |
| RO60 | Ro60, Y RNA binding protein | -0.00526441 |
| C3 | complement component 3 | -0.00525818 |
| AHNAK | AHNAK nucleoprotein | -0.00525392 |
| KIAA0513 | KIAA0513 | -0.00525257 |
| PURA | purine-rich element binding protein A | -0.00524686 |
| OPN3 | opsin 3 | -0.00523061 |
| NPTN | neuroplastin | -0.00520721 |
| SUSD4 | sushi domain containing 4 | -0.00520052 |
| QKI | QKI, KH domain containing, RNA binding | -0.00519861 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | -0.00519793 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00517948 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.005179 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.00517351 |
| TMOD1 | tropomodulin 1 | -0.00517326 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00515674 |
| LEPROT | leptin receptor overlapping transcript | -0.00515483 |
| BIN2 | bridging integrator 2 | -0.00515301 |
| MMP2 | matrix metallopeptidase 2 | -0.00514572 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00512749 |
| TPBG | trophoblast glycoprotein | -0.00511877 |
| IL7R | interleukin 7 receptor | -0.00511116 |
| ERGIC2 | ERGIC and golgi 2 | -0.00509596 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00508958 |
| SCG5 | secretogranin V | -0.00508915 |
| AMH | anti-Mullerian hormone | -0.005087 |
| GOLGA8H | golgin A8 family, member H | -0.00507754 |
