TRPV1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description transient receptor potential cation channel, subfamily V, member 1|Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7442)
External Link https://ncbi.nlm.nih.gov/gene/7442
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Genes

498 genes differentially expressed following the TRPV1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
FGFR3 fibroblast growth factor receptor 3 0.0192213
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0161278
SEPP1 selenoprotein P, plasma, 1 0.0157549
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0151185
KDM5D lysine (K)-specific demethylase 5D 0.0135943
CA2 carbonic anhydrase II 0.0131139
DCK deoxycytidine kinase 0.0117463
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.0116644
NRN1 neuritin 1 0.0115405
ASCL1 achaete-scute family bHLH transcription factor 1 0.0113621
HMGB1 high mobility group box 1 0.0110157
CPVL carboxypeptidase, vitellogenic-like 0.0109418
METTL7A methyltransferase like 7A 0.0108551
PRDX2 peroxiredoxin 2 0.0107359
MAP7 microtubule-associated protein 7 0.0105485
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.0104769
CCNA2 cyclin A2 0.0104475
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.010443
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0103831
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.0101833
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00998829
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00996138
CXCL14 chemokine (C-X-C motif) ligand 14 0.00977926
ZBTB18 zinc finger and BTB domain containing 18 0.00977611
HOXC6 homeobox C6 0.00975682
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0097356
ELANE elastase, neutrophil expressed 0.00972578
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00969265
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00968735
GCA grancalcin, EF-hand calcium binding protein 0.00959958
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00957781
SLC2A4RG SLC2A4 regulator 0.00951688
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00950756
MNDA myeloid cell nuclear differentiation antigen 0.00945537
DCXR dicarbonyl/L-xylulose reductase 0.00945072
DUT deoxyuridine triphosphatase 0.00942923
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00941635
AUTS2 autism susceptibility candidate 2 0.00940974
B3GNT1 0.00938676
KIF20A kinesin family member 20A 0.0093417
TFDP1 transcription factor Dp-1 0.00932254
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00930317
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.0090428
MCM6 minichromosome maintenance complex component 6 0.00904067
ACAT2 acetyl-CoA acetyltransferase 2 0.00895735
FBXO3 F-box protein 3 0.00893768
DHFR dihydrofolate reductase 0.00892481
FTO fat mass and obesity associated 0.0087716
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.00872736
NTS neurotensin 0.00861667
FBXO5 F-box protein 5 0.00860499
PARM1 prostate androgen-regulated mucin-like protein 1 0.00857499
COL4A5 collagen, type IV, alpha 5 0.00853498
CPA3 carboxypeptidase A3 (mast cell) 0.00853298
RPA3 replication protein A3, 14kDa 0.00851845
LMNB1 lamin B1 0.00847389
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00845938
HMGB2 high mobility group box 2 0.00843289
LIG1 ligase I, DNA, ATP-dependent 0.00843278
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00842848
RNF167 ring finger protein 167 0.00842092
LBR lamin B receptor 0.00840171
KIF15 kinesin family member 15 0.00839528
SRRM1 serine/arginine repetitive matrix 1 0.0083071
PER3 period circadian clock 3 0.00820718
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0081421
FAM46C family with sequence similarity 46, member C 0.00812387
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00812052
PCYOX1 prenylcysteine oxidase 1 0.00811267
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00804999
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00803118
ACE2 angiotensin I converting enzyme 2 0.00800428
TRMT5 tRNA methyltransferase 5 0.00800298
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00798899
GANAB glucosidase, alpha; neutral AB 0.00796875
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00794701
TXNIP thioredoxin interacting protein 0.00794671
OLFM4 olfactomedin 4 0.00794426
F13A1 coagulation factor XIII, A1 polypeptide 0.00790849
CDC20 cell division cycle 20 0.00790434
CST3 cystatin C 0.00789599
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 0.00788091
ZNF204P zinc finger protein 204, pseudogene 0.00787369
ZNF652 zinc finger protein 652 0.00786244
NUSAP1 nucleolar and spindle associated protein 1 0.00784035
TSPAN5 tetraspanin 5 0.0078233
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.00776661
PSRC1 proline/serine-rich coiled-coil 1 0.00776048
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00773438
FAR2 fatty acyl CoA reductase 2 0.00773295
KLHL23 kelch-like family member 23 0.00773237
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.0076996
SRSF1 serine/arginine-rich splicing factor 1 0.00767734
HDAC6 histone deacetylase 6 0.00766111
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.00763323
UNC13B unc-13 homolog B (C. elegans) 0.0076325
TMX1 thioredoxin-related transmembrane protein 1 0.00759274
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00758329
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.00756396
GLUL glutamate-ammonia ligase 0.00754091
RRM1 ribonucleotide reductase M1 0.00752903
ZNF124 zinc finger protein 124 0.00751417
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00751248
KHK ketohexokinase (fructokinase) 0.0075058
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 0.00749117
PEX3 peroxisomal biogenesis factor 3 0.00748477
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00745864
SRP9 signal recognition particle 9kDa 0.00743532
TFF3 trefoil factor 3 (intestinal) 0.00742248
SEPHS1 selenophosphate synthetase 1 0.00742075
RSBN1 round spermatid basic protein 1 0.00741031
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.00739733
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.00738821
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00738519
CCNF cyclin F 0.00735108
KRT1 keratin 1, type II 0.00734931
PLPBP pyridoxal phosphate binding protein 0.00733807
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00733
CCNE2 cyclin E2 0.00731479
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00730597
PDHX pyruvate dehydrogenase complex, component X 0.00730408
PDZK1 PDZ domain containing 1 0.00729892
ADAM28 ADAM metallopeptidase domain 28 0.00729536
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.00729149
IL17RB interleukin 17 receptor B 0.00728811
APIP APAF1 interacting protein 0.00726872
FZD5 frizzled class receptor 5 0.00726863
HELLS helicase, lymphoid-specific 0.00722591
CRLF1 cytokine receptor-like factor 1 0.00721761
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.00719659
OLFM1 olfactomedin 1 0.00718804
SNRPA small nuclear ribonucleoprotein polypeptide A 0.00714508
BEX1 brain expressed, X-linked 1 0.00714189
FCGBP Fc fragment of IgG binding protein 0.00713502
PRTN3 proteinase 3 0.00713481
HAT1 histone acetyltransferase 1 0.0071183
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00709558
NCAPG2 non-SMC condensin II complex, subunit G2 0.0070816
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00707334
ZNF274 zinc finger protein 274 0.00705625
PRC1 protein regulator of cytokinesis 1 0.0070484
CNTNAP2 contactin associated protein-like 2 0.00703721
OIP5 Opa interacting protein 5 0.00703057
BCL2 B-cell CLL/lymphoma 2 0.00695123
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.00694695
C12ORF29 chromosome 12 open reading frame 29 0.00694033
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00693071
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00691399
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00690437
LRP2 low density lipoprotein receptor-related protein 2 0.00690407
CLEC10A C-type lectin domain family 10, member A 0.00690365
AOC1 amine oxidase, copper containing 1 0.00689666
TMEM106B transmembrane protein 106B 0.00688745
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00686543
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 0.00686406
PDIA3 protein disulfide isomerase family A, member 3 0.0068631
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00685379
NEK4 NIMA-related kinase 4 0.00684751
MMP12 matrix metallopeptidase 12 0.00684465
THAP12 THAP domain containing 12 0.00683853
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00683404
CANX calnexin 0.00683345
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.0068269
AQP1 aquaporin 1 (Colton blood group) 0.00680932
ACYP1 acylphosphatase 1, erythrocyte (common) type 0.00679207
ARG1 arginase 1 0.00677684
CALML4 calmodulin-like 4 0.00677332
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00677002
PDK1 pyruvate dehydrogenase kinase, isozyme 1 0.0067626
DDHD2 DDHD domain containing 2 0.00674946
ADD3 adducin 3 (gamma) 0.00674923
FAM3C family with sequence similarity 3, member C 0.00674853
FOXC1 forkhead box C1 0.00674589
MAP2K6 mitogen-activated protein kinase kinase 6 0.00674339
RAD23B RAD23 homolog B (S. cerevisiae) 0.00674248
DMAC2L distal membrane arm assembly component 2 like 0.00673619
GCK glucokinase (hexokinase 4) 0.0067282
AMACR alpha-methylacyl-CoA racemase 0.00669385
DHRS11 dehydrogenase/reductase (SDR family) member 11 0.00665269
EGLN3 egl-9 family hypoxia-inducible factor 3 0.00664715
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00663599
CDCA4 cell division cycle associated 4 0.00662804
GET1 guided entry of tail-anchored proteins factor 1 0.00661548
LTBP1 latent transforming growth factor beta binding protein 1 0.00660589
TIMELESS timeless circadian clock 0.00658888
ABHD10 abhydrolase domain containing 10 0.00658285
TSPAN6 tetraspanin 6 0.00658107
VANGL1 VANGL planar cell polarity protein 1 0.00656945
XPO7 exportin 7 0.00656913
NIPSNAP2 nipsnap homolog 2 0.00654529
H1-10 H1.10 linker histone 0.00654361
MPO myeloperoxidase 0.00652955
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.00651794
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00651555
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00651512
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00650884
LOR loricrin 0.00650402
TMBIM4 transmembrane BAX inhibitor motif containing 4 0.00650014
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00649346
IGFBP5 insulin-like growth factor binding protein 5 0.00649212
TDP1 tyrosyl-DNA phosphodiesterase 1 0.00648563
NRGN neurogranin (protein kinase C substrate, RC3) 0.00648441
PSIP1 PC4 and SFRS1 interacting protein 1 0.00647824
CBR4 carbonyl reductase 4 0.00647531
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.006474
SUB1 SUB1 homolog (S. cerevisiae) 0.00647296
FASN fatty acid synthase 0.00642968
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00641885
EPHA4 EPH receptor A4 0.00641872
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 0.00641807
RESF1 retroelement silencing factor 1 0.00640313
ECI2 enoyl-CoA delta isomerase 2 0.0063945
CCND2 cyclin D2 0.00638276
EXOC5 exocyst complex component 5 0.0063736
NEMP1 nuclear envelope integral membrane protein 1 0.00635238
SCAMP1 secretory carrier membrane protein 1 0.00635082
MCM2 minichromosome maintenance complex component 2 0.00634705
SATB2 SATB homeobox 2 0.00634688
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.00633738
CLC Charcot-Leyden crystal galectin 0.00632377
CDC42 cell division cycle 42 0.0063073
GPSM2 G-protein signaling modulator 2 0.00630588
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00630415
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.00630065
CDK14 cyclin-dependent kinase 14 0.00628963
UFL1 UFM1-specific ligase 1 0.00628913
MDM1 Mdm1 nuclear protein homolog (mouse) 0.00628847
ATG5 autophagy related 5 0.00628605
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.00628161
TOX3 TOX high mobility group box family member 3 0.00626608
RBBP4 retinoblastoma binding protein 4 0.00625538
PLPP3 phospholipid phosphatase 3 0.00625471
DBF4 DBF4 zinc finger 0.00624742
SIRT3 sirtuin 3 0.00624297
LEFTY1 left-right determination factor 1 0.00623852
POT1 protection of telomeres 1 0.00623161
AZU1 azurocidin 1 0.00622725
ZCCHC10 zinc finger, CCHC domain containing 10 0.00621728
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.00621409
CFD complement factor D (adipsin) 0.00621328
NBPF10 neuroblastoma breakpoint family, member 10 0.00620274
WDR61 WD repeat domain 61 0.00619628
TIPRL TOR signaling pathway regulator 0.00619316
GLO1 glyoxalase I 0.00619185
KIF1B kinesin family member 1B 0.00618821
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.00618686
LIPT1 lipoyltransferase 1 0.00616314
SMC2 structural maintenance of chromosomes 2 0.00616217
RMI1 RecQ mediated genome instability 1 0.00615391
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.00614038

decreased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A -0.029578
KRT7 keratin 7, type II -0.0213335
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0203068
HSPB1 heat shock 27kDa protein 1 -0.0190312
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0188142
ATF3 activating transcription factor 3 -0.0187386
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0184433
TM4SF1 transmembrane 4 L six family member 1 -0.0183247
IFI27 interferon, alpha-inducible protein 27 -0.0180162
MX1 MX dynamin-like GTPase 1 -0.0174978
ECM1 extracellular matrix protein 1 -0.017363
LCN2 lipocalin 2 -0.017222
IER5 immediate early response 5 -0.017172
HMOX1 heme oxygenase 1 -0.0170264
ISG15 ISG15 ubiquitin-like modifier -0.0165433
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0164222
AKR1C2 aldo-keto reductase family 1, member C2 -0.0159403
XIC X chromosome inactivation center -0.0154402
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0153158
PLK2 polo-like kinase 2 -0.0152098
FTH1 ferritin, heavy polypeptide 1 -0.0149203
HSPB8 heat shock 22kDa protein 8 -0.014567
TNNC1 troponin C type 1 (slow) -0.0145315
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0143182
CTSL cathepsin L -0.0140991
C3 complement component 3 -0.0140325
VEGFA vascular endothelial growth factor A -0.0140146
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0137899
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0137495
HIST1H2BK histone cluster 1, H2bk -0.0136622
KRT19 keratin 19, type I -0.0136545
MMP7 matrix metallopeptidase 7 -0.013621
CXCL2 chemokine (C-X-C motif) ligand 2 -0.0131206
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0130412
CKM creatine kinase, muscle -0.0130138
IFI6 interferon, alpha-inducible protein 6 -0.0129443
C1S complement component 1, s subcomponent -0.0129241
MYBPC1 myosin binding protein C, slow type -0.012768
CCL20 chemokine (C-C motif) ligand 20 -0.0127616
INHBA inhibin, beta A -0.0127533
MGLL monoglyceride lipase -0.0127128
FN1 fibronectin 1 -0.0126764
KLK11 kallikrein-related peptidase 11 -0.0125878
RND3 Rho family GTPase 3 -0.0124851
AKR1C1 aldo-keto reductase family 1, member C1 -0.0122967
TGFBI transforming growth factor, beta-induced, 68kDa -0.0122702
MVP major vault protein -0.0122495
CRYAB crystallin, alpha B -0.0121766
THBS2 thrombospondin 2 -0.0121559
IFI44 interferon-induced protein 44 -0.0121089
IL32 interleukin 32 -0.0120474
SQSTM1 sequestosome 1 -0.0119269
IRS1 insulin receptor substrate 1 -0.0118646
MLPH melanophilin -0.0118584
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0117832
SIK1 salt-inducible kinase 1 -0.0116884
SPON2 spondin 2, extracellular matrix protein -0.0115662
DYNLL1 dynein, light chain, LC8-type 1 -0.0115266
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -0.0115245
BIK BCL2-interacting killer (apoptosis-inducing) -0.0114568
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.0114363
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0113983
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.011376
CEL carboxyl ester lipase -0.0113619
CCN2 cellular communication network factor 2 -0.0113062
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.011289
KRT8 keratin 8, type II -0.0112641
ABHD4 abhydrolase domain containing 4 -0.0112345
SRPX sushi-repeat containing protein, X-linked -0.0111799
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0111326
ASS1 argininosuccinate synthase 1 -0.0111255
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.0111199
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0111185
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0110746
DSP desmoplakin -0.011003
KYNU kynureninase -0.0109784
TUBB6 tubulin, beta 6 class V -0.0109763
CEMIP cell migration inducing protein, hyaluronan binding -0.0109728
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.0109085
G0S2 G0/G1 switch 2 -0.0108825
SMAD3 SMAD family member 3 -0.0108773
TFPI2 tissue factor pathway inhibitor 2 -0.0108568
KRT23 keratin 23, type I -0.0108464
KRT18 keratin 18, type I -0.010816
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0108134
ISG20 interferon stimulated exonuclease gene 20kDa -0.0107866
MMP1 matrix metallopeptidase 1 -0.0107813
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.0107714
GBP2 guanylate binding protein 2, interferon-inducible -0.0107588
PRSS23 protease, serine, 23 -0.0107442
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0106301
GPNMB glycoprotein (transmembrane) nmb -0.0106282
HIST1H2BD histone cluster 1, H2bd -0.010619
PLPP2 phospholipid phosphatase 2 -0.0105853
PDLIM5 PDZ and LIM domain 5 -0.0105471
ETFB electron-transfer-flavoprotein, beta polypeptide -0.0105089
RTN2 reticulon 2 -0.0104523
TNIP1 TNFAIP3 interacting protein 1 -0.010444
S100P S100 calcium binding protein P -0.0104304
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.0104259
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.0104141
KLHL41 kelch-like family member 41 -0.0102815
COL6A3 collagen, type VI, alpha 3 -0.0102805
SYNM synemin, intermediate filament protein -0.010272
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.0102594
NRCAM neuronal cell adhesion molecule -0.0102539
FHL2 four and a half LIM domains 2 -0.0102491
S100A11 S100 calcium binding protein A11 -0.0102424
EGFL6 EGF-like-domain, multiple 6 -0.0102163
IL1RN interleukin 1 receptor antagonist -0.0101915
MIR22HG MIR22 host gene -0.0101579
FGG fibrinogen gamma chain -0.0101272
MAGEA3 melanoma antigen family A3 -0.0101003
S100A10 S100 calcium binding protein A10 -0.0100139
TNNC2 troponin C type 2 (fast) -0.00999971
DCN decorin -0.00997237
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00994285
MMP19 matrix metallopeptidase 19 -0.00989218
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00988516
TUFT1 tuftelin 1 -0.00987357
KLK10 kallikrein-related peptidase 10 -0.00982101
FGB fibrinogen beta chain -0.00976302
ANXA1 annexin A1 -0.00973604
DES desmin -0.00971311
NEU1 sialidase 1 (lysosomal sialidase) -0.00968419
SLPI secretory leukocyte peptidase inhibitor -0.00967628
MX2 MX dynamin-like GTPase 2 -0.00964989
GPX3 glutathione peroxidase 3 -0.00964873
LAMB3 laminin, beta 3 -0.00962279
SGK1 serum/glucocorticoid regulated kinase 1 -0.00959787
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00959638
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00956729
S100A4 S100 calcium binding protein A4 -0.00954246
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0095232
AMOTL2 angiomotin like 2 -0.0094849
TRIM16 tripartite motif containing 16 -0.00942997
SLN sarcolipin -0.00941576
MET MET proto-oncogene, receptor tyrosine kinase -0.00938806
C9ORF3 chromosome 9 open reading frame 3 -0.00938093
IFI35 interferon-induced protein 35 -0.00935878
IFI44L interferon-induced protein 44-like -0.00933403
RPS27L ribosomal protein S27-like -0.00930063
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00929005
VGLL4 vestigial-like family member 4 -0.00928224
TTN titin -0.00924896
MFAP5 microfibrillar associated protein 5 -0.00923575
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00915307
MEIS1 Meis homeobox 1 -0.00912742
LAMB1 laminin, beta 1 -0.009109
RFTN1 raftlin, lipid raft linker 1 -0.00907963
VNN1 vanin 1 -0.00905886
MYOT myotilin -0.00905815
TPM1 tropomyosin 1 (alpha) -0.00903938
FABP4 fatty acid binding protein 4, adipocyte -0.0090093
NUPR1 nuclear protein, transcriptional regulator, 1 -0.009006
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00900418
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00900415
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00899771
LUM lumican -0.00897366
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00895874
MYOF myoferlin -0.00893747
ACTA1 actin, alpha 1, skeletal muscle -0.00890398
MITF microphthalmia-associated transcription factor -0.00890375
MB myoglobin -0.00888582
EPHA2 EPH receptor A2 -0.0088797
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00886004
IL6 interleukin 6 -0.00882146
KRT14 keratin 14, type I -0.00881453
AK1 adenylate kinase 1 -0.00880519
IFI30 interferon, gamma-inducible protein 30 -0.0087907
RGS4 regulator of G-protein signaling 4 -0.00873539
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00873314
PDE4DIP phosphodiesterase 4D interacting protein -0.00872557
TFRC transferrin receptor -0.00870816
CYTH1 cytohesin 1 -0.0086858
EMP1 epithelial membrane protein 1 -0.00865573
ITGAV integrin, alpha V -0.0086534
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00863268
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00863031
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00862516
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00859135
H1-2 H1.2 linker histone, cluster member -0.00857933
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00857365
NNMT nicotinamide N-methyltransferase -0.00852397
CFB complement factor B -0.00852098
TNNI2 troponin I type 2 (skeletal, fast) -0.00851365
LRRC15 leucine rich repeat containing 15 -0.00850075
OXTR oxytocin receptor -0.00847161
COL15A1 collagen, type XV, alpha 1 -0.00846986
GEM GTP binding protein overexpressed in skeletal muscle -0.00845642
FILIP1L filamin A interacting protein 1-like -0.00844808
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00843751
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.0084149
NPC1 Niemann-Pick disease, type C1 -0.00840124
KLF6 Kruppel-like factor 6 -0.0083951
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00838283
SCGB2A1 secretoglobin, family 2A, member 1 -0.00838052
ZMAT3 zinc finger, matrin-type 3 -0.00837332
PLK3 polo-like kinase 3 -0.00837217
LMCD1 LIM and cysteine-rich domains 1 -0.00836477
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00836137
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00836096
IFRD1 interferon-related developmental regulator 1 -0.00835568
PERP PERP, TP53 apoptosis effector -0.00833905
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00830777
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00828733
JMJD6 jumonji domain containing 6 -0.00826389
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00822231
IRS2 insulin receptor substrate 2 -0.00819192
SMPX small muscle protein, X-linked -0.0081549
MXRA5 matrix-remodelling associated 5 -0.00815361
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -0.00814859
EGR2 early growth response 2 -0.00811468
GNAS GNAS complex locus -0.0080686
OSR2 odd-skipped related transciption factor 2 -0.00803615
LIMCH1 LIM and calponin homology domains 1 -0.00802816
MOXD1 monooxygenase, DBH-like 1 -0.0080102
PLAAT3 phospholipase A and acyltransferase 3 -0.00798109
APOD apolipoprotein D -0.00794469
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.0079417
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00794158
MUC16 mucin 16, cell surface associated -0.00793977
CTSB cathepsin B -0.00793965
NAMPT nicotinamide phosphoribosyltransferase -0.00793491
IL1R1 interleukin 1 receptor, type I -0.00792367
TM4SF4 transmembrane 4 L six family member 4 -0.00790702
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00789615
RAB9A RAB9A, member RAS oncogene family -0.00788102
AHNAK2 AHNAK nucleoprotein 2 -0.00787918
OASL 2'-5'-oligoadenylate synthetase-like -0.00787247
PHLDA3 pleckstrin homology-like domain, family A, member 3 -0.00785701
PSCA prostate stem cell antigen -0.0078555
ZFPM2 zinc finger protein, FOG family member 2 -0.00785428
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00783257
EFNA1 ephrin-A1 -0.00782765
VEGFC vascular endothelial growth factor C -0.00780644
ANXA2P2 annexin A2 pseudogene 2 -0.00775506
KRT15 keratin 15, type I -0.00773215
STC2 stanniocalcin 2 -0.00771336
JUNB jun B proto-oncogene -0.00770181
HIST1H2AC histone cluster 1, H2ac -0.00770081
PEG10 paternally expressed 10 -0.00769979
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00769781
THBS4 thrombospondin 4 -0.00768654
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00768451
TNS3 tensin 3 -0.00767175
HOMER1 homer scaffolding protein 1 -0.00767007
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle -0.00766853