TRPV2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description transient receptor potential cation channel, subfamily V, member 2|This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 51393)
External Link https://ncbi.nlm.nih.gov/gene/51393
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Genes

500 genes differentially expressed following the TRPV2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
WASHC4 WASH complex subunit 4 0.0199684
GAS1 growth arrest-specific 1 0.0168565
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0164402
CXCL12 chemokine (C-X-C motif) ligand 12 0.0148829
S100A7 S100 calcium binding protein A7 0.0129332
SEPP1 selenoprotein P, plasma, 1 0.0128666
CSTA cystatin A (stefin A) 0.0117896
FCGBP Fc fragment of IgG binding protein 0.0117296
C7 complement component 7 0.0113801
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.011289
TMEM45A transmembrane protein 45A 0.0107713
TGFBR3 transforming growth factor, beta receptor III 0.0105866
LY6D lymphocyte antigen 6 complex, locus D 0.010566
TUBB2A tubulin, beta 2A class IIa 0.0104117
MARCKS myristoylated alanine-rich protein kinase C substrate 0.0103585
CHGB chromogranin B 0.0102017
OLFM1 olfactomedin 1 0.0101681
SRPX sushi-repeat containing protein, X-linked 0.00996529
MEN1 multiple endocrine neoplasia I 0.00994788
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00975073
ANK2 ankyrin 2, neuronal 0.0097493
BHLHE41 basic helix-loop-helix family, member e41 0.0096639
CCNB1 cyclin B1 0.00954676
TFRC transferrin receptor 0.00937716
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00931141
PBX1 pre-B-cell leukemia homeobox 1 0.0093049
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00915561
SPRR1B small proline-rich protein 1B 0.00910212
IGFBP5 insulin-like growth factor binding protein 5 0.00909171
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00908526
MATN2 matrilin 2 0.00890861
DCN decorin 0.00886784
FABP7 fatty acid binding protein 7, brain 0.00884949
PDE4B phosphodiesterase 4B, cAMP-specific 0.00877016
PEG3 paternally expressed 3 0.00875601
CALML5 calmodulin-like 5 0.00869872
RRM2 ribonucleotide reductase M2 0.0085708
PALLD palladin, cytoskeletal associated protein 0.00854269
LIMA1 LIM domain and actin binding 1 0.00852244
INSM1 insulinoma-associated 1 0.00849478
DEFB1 defensin, beta 1 0.0084819
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00842887
WT1 Wilms tumor 1 0.00841358
HNMT histamine N-methyltransferase 0.00840374
KLK8 kallikrein-related peptidase 8 0.00839046
MEIS1 Meis homeobox 1 0.00838699
KRT19 keratin 19, type I 0.00837945
UBE2N ubiquitin-conjugating enzyme E2N 0.00834124
MSMO1 methylsterol monooxygenase 1 0.00827727
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0082384
COL3A1 collagen, type III, alpha 1 0.00814658
SFRP4 secreted frizzled-related protein 4 0.00814612
ARHGAP32 Rho GTPase activating protein 32 0.00813299
KRT1 keratin 1, type II 0.0081304
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.00806902
CLDN10 claudin 10 0.00805789
KLK7 kallikrein-related peptidase 7 0.00801225
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00801065
GUCY2C guanylate cyclase 2C 0.00800197
PSD3 pleckstrin and Sec7 domain containing 3 0.00789997
SPARCL1 SPARC-like 1 (hevin) 0.00784595
MREG melanoregulin 0.00780686
RAB25 RAB25, member RAS oncogene family 0.00780092
FERMT1 fermitin family member 1 0.00776706
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00776584
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00776015
SSPN sarcospan 0.00774735
NFASC neurofascin 0.00771297
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00767337
CALD1 caldesmon 1 0.00767094
XPO7 exportin 7 0.00766926
SQLE squalene epoxidase 0.00766015
PMP22 peripheral myelin protein 22 0.00762738
KCTD12 potassium channel tetramerization domain containing 12 0.007579
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00752994
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00750014
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.0074927
VCAM1 vascular cell adhesion molecule 1 0.00749261
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00746587
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.00744065
LYZ lysozyme 0.00743696
TCF21 transcription factor 21 0.00741909
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00740716
OLFM4 olfactomedin 4 0.00739978
SFRP1 secreted frizzled-related protein 1 0.00734861
COL14A1 collagen, type XIV, alpha 1 0.00731188
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.007308
FGFR1 fibroblast growth factor receptor 1 0.00730623
CST6 cystatin E/M 0.00729355
OAT ornithine aminotransferase 0.00729295
ADAM28 ADAM metallopeptidase domain 28 0.00728548
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00725775
COL10A1 collagen, type X, alpha 1 0.00723083
NUSAP1 nucleolar and spindle associated protein 1 0.00722358
CFD complement factor D (adipsin) 0.00721062
HLTF helicase-like transcription factor 0.00720256
PDGFRL platelet-derived growth factor receptor-like 0.0071944
GPM6B glycoprotein M6B 0.00718684
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00714744
ASCL1 achaete-scute family bHLH transcription factor 1 0.00714208
TIMP3 TIMP metallopeptidase inhibitor 3 0.00710585
RET ret proto-oncogene 0.00710084
DOK5 docking protein 5 0.0070122
LUM lumican 0.00699515
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00696468
ZFPM2 zinc finger protein, FOG family member 2 0.00696279
S100A2 S100 calcium binding protein A2 0.00693864
SRSF6 serine/arginine-rich splicing factor 6 0.00692841
KLK6 kallikrein-related peptidase 6 0.0069141
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00687346
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00686003
TOX3 TOX high mobility group box family member 3 0.00680858
SNCAIP synuclein, alpha interacting protein 0.00679669
CRISP3 cysteine-rich secretory protein 3 0.00678517
FBXO21 F-box protein 21 0.00674887
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00673977
CHD7 chromodomain helicase DNA binding protein 7 0.00671179
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00668514
PLSCR4 phospholipid scramblase 4 0.00665408
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0066475
THBS1 thrombospondin 1 0.00662125
PDLIM3 PDZ and LIM domain 3 0.00661811
LTBP1 latent transforming growth factor beta binding protein 1 0.00658906
BMPR1A bone morphogenetic protein receptor, type IA 0.00657553
FRS2 fibroblast growth factor receptor substrate 2 0.00656957
HOXC6 homeobox C6 0.00656242
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00654868
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.00654819
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 0.00654638
NFYB nuclear transcription factor Y, beta 0.00653125
CCNA2 cyclin A2 0.00650206
SLURP1 secreted LY6/PLAUR domain containing 1 0.00649578
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00646674
SH3YL1 SH3 and SYLF domain containing 1 0.00643757
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.00642232
NFIB nuclear factor I/B 0.00639814
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00637444
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0063663
C1R complement component 1, r subcomponent 0.00634314
HEPH hephaestin 0.00633681
PLN phospholamban 0.00633308
PER3 period circadian clock 3 0.00631238
KRT2 keratin 2, type II 0.00630204
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00630166
UNG uracil-DNA glycosylase 0.00629461
KRT6A keratin 6A, type II 0.00629035
BICC1 BicC family RNA binding protein 1 0.00629012
FOXC1 forkhead box C1 0.00628893
SPRR2B small proline-rich protein 2B 0.00628656
LOXL1 lysyl oxidase-like 1 0.00628501
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00627386
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 0.00627144
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00626906
TLCD3A TLC domain containing 3A 0.00626829
PI3 peptidase inhibitor 3, skin-derived 0.00626699
PLAGL1 pleiomorphic adenoma gene-like 1 0.00626383
TACC1 transforming, acidic coiled-coil containing protein 1 0.00624655
HOXA5 homeobox A5 0.00623994
DMXL2 Dmx-like 2 0.00622504
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00621033
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00619488
GAL galanin/GMAP prepropeptide 0.00619424
SPRR1A small proline-rich protein 1A 0.00619102
WFDC1 WAP four-disulfide core domain 1 0.00617861
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00617608
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00617409
NEBL nebulette 0.00617182
PLAT plasminogen activator, tissue 0.00616931
TYRP1 tyrosinase-related protein 1 0.0061658
FBLN1 fibulin 1 0.00615298
ZNF185 zinc finger protein 185 (LIM domain) 0.00613929
COL4A5 collagen, type IV, alpha 5 0.00612044
MEIS2 Meis homeobox 2 0.0061197
HOPX HOP homeobox 0.00611605
CCNE2 cyclin E2 0.00611349
CAND1 cullin-associated and neddylation-dissociated 1 0.00609962
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00609917
ASPN asporin 0.0060819
LYPD3 LY6/PLAUR domain containing 3 0.00607346
KIAA0226L KIAA0226-like 0.0060674
RBM38 RNA binding motif protein 38 0.00605251
SGCE sarcoglycan, epsilon 0.00599411
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00598197
STON1 stonin 1 0.00597848
CLDN8 claudin 8 0.00597093
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00597082
C12ORF29 chromosome 12 open reading frame 29 0.00595626
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.00593809
TRIM14 tripartite motif containing 14 0.00592761
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.0059232
IMPACT impact RWD domain protein 0.00590197
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.00589813
TTC3 tetratricopeptide repeat domain 3 0.0058744
AHNAK2 AHNAK nucleoprotein 2 0.00587336
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.00586627
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00585082
PBX3 pre-B-cell leukemia homeobox 3 0.00582629
PTK6 protein tyrosine kinase 6 0.00581021
COG5 component of oligomeric golgi complex 5 0.00580245
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00579664
FXYD3 FXYD domain containing ion transport regulator 3 0.0057854
RAB4A RAB4A, member RAS oncogene family 0.00578236
MFAP4 microfibrillar-associated protein 4 0.00577309
XK X-linked Kx blood group 0.00576239
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00576218
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.00574324
DLD dihydrolipoamide dehydrogenase 0.00572811
MMP12 matrix metallopeptidase 12 0.00568924
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00568702
NAP1L3 nucleosome assembly protein 1-like 3 0.00567929
TMEM255A transmembrane protein 255A 0.00567792
PDLIM5 PDZ and LIM domain 5 0.00567155
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00566817
KIF1B kinesin family member 1B 0.00564878
PMP2 peripheral myelin protein 2 0.00564346
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00563454
USP46 ubiquitin specific peptidase 46 0.00563148
S100A14 S100 calcium binding protein A14 0.00562634
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00562352
TMPRSS4 transmembrane protease, serine 4 0.00562026
COL16A1 collagen, type XVI, alpha 1 0.00559548
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00559346
PERP PERP, TP53 apoptosis effector 0.00557679
BUB3 BUB3 mitotic checkpoint protein 0.00557246
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.0055716
PRUNE2 prune homolog 2 (Drosophila) 0.00556102
PRSS3 protease, serine, 3 0.00555371
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.00554541
TNC tenascin C 0.00553879
ADAMDEC1 ADAM-like, decysin 1 0.00553513
CLCA4 chloride channel accessory 4 0.00552897
CSDE1 cold shock domain containing E1, RNA-binding 0.00552726
KRT13 keratin 13, type I 0.00552711
SET SET nuclear proto-oncogene 0.00552568
MXRA5 matrix-remodelling associated 5 0.00549842
TACSTD2 tumor-associated calcium signal transducer 2 0.00549439
COL9A3 collagen, type IX, alpha 3 0.00548799
PLAU plasminogen activator, urokinase 0.00548422
TFDP1 transcription factor Dp-1 0.00547825
DZIP1 DAZ interacting zinc finger protein 1 0.00547295
DPYSL3 dihydropyrimidinase-like 3 0.00547034
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.00543436
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00543015
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00541606
POU4F1 POU class 4 homeobox 1 0.00541535
FXYD6 FXYD domain containing ion transport regulator 6 0.00541399
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00541206
THBS2 thrombospondin 2 0.00540853
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00539921
KIF11 kinesin family member 11 0.00539891

decreased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0184328
CHP1 calcineurin-like EF-hand protein 1 -0.0169802
MET MET proto-oncogene, receptor tyrosine kinase -0.0128452
WIF1 WNT inhibitory factor 1 -0.0125129
HSPA1A heat shock 70kDa protein 1A -0.0119869
MEF2C myocyte enhancer factor 2C -0.0118584
TGFB1 transforming growth factor, beta 1 -0.011614
AKR1C3 aldo-keto reductase family 1, member C3 -0.0114722
AKR1C1 aldo-keto reductase family 1, member C1 -0.0105709
PLK2 polo-like kinase 2 -0.0104713
ABHD4 abhydrolase domain containing 4 -0.010415
IFI6 interferon, alpha-inducible protein 6 -0.0099691
WARS1 tryptophanyl-tRNA synthetase 1 -0.00996419
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00994353
DDR2 discoidin domain receptor tyrosine kinase 2 -0.0096914
NRGN neurogranin (protein kinase C substrate, RC3) -0.00928824
IFITM1 interferon induced transmembrane protein 1 -0.00923704
WFDC2 WAP four-disulfide core domain 2 -0.00910365
PXDC1 PX domain containing 1 -0.0089918
DYNLL1 dynein, light chain, LC8-type 1 -0.00895888
KRT18 keratin 18, type I -0.00891797
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00886268
AKR1C2 aldo-keto reductase family 1, member C2 -0.00883697
TPBG trophoblast glycoprotein -0.00875259
RHOB ras homolog family member B -0.00863221
IFITM2 interferon induced transmembrane protein 2 -0.00853511
EXT1 exostosin glycosyltransferase 1 -0.00836646
ADM adrenomedullin -0.00828402
JUP junction plakoglobin -0.00826347
STC2 stanniocalcin 2 -0.00823696
MYOF myoferlin -0.00822473
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00822325
TFPI2 tissue factor pathway inhibitor 2 -0.00821146
CNPY3 canopy FGF signaling regulator 3 -0.00818123
S100A12 S100 calcium binding protein A12 -0.0081249
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -0.00808978
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00804039
GIMAP6 GTPase, IMAP family member 6 -0.00798511
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.00796925
G6PD glucose-6-phosphate dehydrogenase -0.00788588
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00782647
FTH1 ferritin, heavy polypeptide 1 -0.00778845
S100A11 S100 calcium binding protein A11 -0.00771478
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00769329
NEU1 sialidase 1 (lysosomal sialidase) -0.00768315
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00768179
TPD52L1 tumor protein D52-like 1 -0.00760612
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00757674
IFI30 interferon, gamma-inducible protein 30 -0.00755916
FPR1 formyl peptide receptor 1 -0.00747331
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00744544
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00740511
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -0.007401
RETREG1 reticulophagy regulator 1 -0.00734146
PRAME preferentially expressed antigen in melanoma -0.00729602
ADGRF5 adhesion G protein-coupled receptor F5 -0.00728969
HMOX1 heme oxygenase 1 -0.00724447
GPX3 glutathione peroxidase 3 -0.00723421
TAC1 tachykinin, precursor 1 -0.00720029
ERGIC3 ERGIC and golgi 3 -0.00718637
RNF167 ring finger protein 167 -0.00718089
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00715952
FXR1 fragile X mental retardation, autosomal homolog 1 -0.00713224
GADD45B growth arrest and DNA-damage-inducible, beta -0.00711258
ECM1 extracellular matrix protein 1 -0.0071037
RIT1 Ras-like without CAAX 1 -0.00709099
HIST1H2BK histone cluster 1, H2bk -0.00707669
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00699585
IER5 immediate early response 5 -0.00698185
S100A10 S100 calcium binding protein A10 -0.00698087
C4BPA complement component 4 binding protein, alpha -0.00693752
BAG3 BCL2-associated athanogene 3 -0.0069031
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00689082
TRIP6 thyroid hormone receptor interactor 6 -0.00686232
PGF placental growth factor -0.00685997
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00684127
TGIF1 TGFB-induced factor homeobox 1 -0.00684126
FXYD5 FXYD domain containing ion transport regulator 5 -0.00681078
MECOM MDS1 and EVI1 complex locus -0.0068019
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00668447
PRKCSH protein kinase C substrate 80K-H -0.00666971
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00666771
VGLL4 vestigial-like family member 4 -0.00655491
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00653117
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00652822
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00650336
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00649971
CST3 cystatin C -0.00641702
MYH10 myosin, heavy chain 10, non-muscle -0.0064131
TIMP1 TIMP metallopeptidase inhibitor 1 -0.006376
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00636933
ANXA4 annexin A4 -0.0063652
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00635752
MVP major vault protein -0.0063497
CCDC92 coiled-coil domain containing 92 -0.00633627
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00633031
TMEM140 transmembrane protein 140 -0.00633006
PKP4 plakophilin 4 -0.006321
TNNT1 troponin T type 1 (skeletal, slow) -0.00629916
KLHL24 kelch-like family member 24 -0.00629347
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -0.00629201
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.00621146
SORBS2 sorbin and SH3 domain containing 2 -0.0062061
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -0.0061955
BST2 bone marrow stromal cell antigen 2 -0.0061783
DLX5 distal-less homeobox 5 -0.00615621
IGFBP6 insulin-like growth factor binding protein 6 -0.00614486
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00614417
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0060956
CALCOCO2 calcium binding and coiled-coil domain 2 -0.00609163
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00606144
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00606074
LPAR6 lysophosphatidic acid receptor 6 -0.00604078
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00603555
SELL selectin L -0.0060231
FKBP11 FK506 binding protein 11, 19 kDa -0.00601897
EGFL7 EGF-like-domain, multiple 7 -0.00601598
TPST2 tyrosylprotein sulfotransferase 2 -0.00598991
GIMAP4 GTPase, IMAP family member 4 -0.00598839
RBM42 RNA binding motif protein 42 -0.00597601
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00597568
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.00596928
ABHD2 abhydrolase domain containing 2 -0.00595489
UPP1 uridine phosphorylase 1 -0.00595148
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 -0.0059512
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00594171
LRP4 low density lipoprotein receptor-related protein 4 -0.00592962
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00588934
PLXND1 plexin D1 -0.00588912
NKX2-1 NK2 homeobox 1 -0.00587952
HSPB1 heat shock 27kDa protein 1 -0.00587868
ELOVL5 ELOVL fatty acid elongase 5 -0.00585685
ZBTB38 zinc finger and BTB domain containing 38 -0.00585456
MINK1 misshapen-like kinase 1 -0.0058505
FLT1 fms-related tyrosine kinase 1 -0.00584381
BSG basigin (Ok blood group) -0.00583831
GDF15 growth differentiation factor 15 -0.00580848
MDK midkine (neurite growth-promoting factor 2) -0.0057851
SQSTM1 sequestosome 1 -0.00577231
RGS4 regulator of G-protein signaling 4 -0.00577215
TNIP1 TNFAIP3 interacting protein 1 -0.00575883
PLD3 phospholipase D family, member 3 -0.00575278
HSPB8 heat shock 22kDa protein 8 -0.00574876
MLPH melanophilin -0.00573626
LY96 lymphocyte antigen 96 -0.00573002
ISG15 ISG15 ubiquitin-like modifier -0.00571892
RGS3 regulator of G-protein signaling 3 -0.00568872
ARF3 ADP-ribosylation factor 3 -0.00568609
ALCAM activated leukocyte cell adhesion molecule -0.00565942
HEXB hexosaminidase B (beta polypeptide) -0.00564474
MYO1B myosin IB -0.00560503
NPC2 Niemann-Pick disease, type C2 -0.00559026
PLAAT3 phospholipase A and acyltransferase 3 -0.00558251
IGF2R insulin-like growth factor 2 receptor -0.00558197
PKM pyruvate kinase, muscle -0.00557046
EFNA1 ephrin-A1 -0.00553527
PNKP polynucleotide kinase 3'-phosphatase -0.00552985
BRD4 bromodomain containing 4 -0.00552642
FZD2 frizzled class receptor 2 -0.00552154
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.00549775
IL13RA2 interleukin 13 receptor, alpha 2 -0.00548481
CAPNS1 calpain, small subunit 1 -0.00546352
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00546247
MT1E metallothionein 1E -0.00544356
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.00542325
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00540523
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.0054047
CCDC86 coiled-coil domain containing 86 -0.00540267
LEF1 lymphoid enhancer-binding factor 1 -0.00539884
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00539787
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.00538577
GRN granulin -0.00538121
COA3 cytochrome c oxidase assembly factor 3 -0.00537223
GOLIM4 golgi integral membrane protein 4 -0.0053627
BCL2L1 BCL2-like 1 -0.0053547
JCHAIN joining chain of multimeric IgA and IgM -0.00535083
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00534228
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.00533637
GSTP1 glutathione S-transferase pi 1 -0.00530407
BASP1 brain abundant, membrane attached signal protein 1 -0.0052849
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00523243
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.00523221
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00521981
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00521608
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.00520995
BMP2 bone morphogenetic protein 2 -0.00519102
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00518715
NFE2 nuclear factor, erythroid 2 -0.00518156
NUTF2 nuclear transport factor 2 -0.00517592
AK5 adenylate kinase 5 -0.00516565
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.00516104
NECAB3 N-terminal EF-hand calcium binding protein 3 -0.00516086
CTSL cathepsin L -0.00516028
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00515458
TSPAN14 tetraspanin 14 -0.00515344
DDIT4 DNA-damage-inducible transcript 4 -0.0051533
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -0.00514022
FOLR1 folate receptor 1 (adult) -0.00513928
TNNC1 troponin C type 1 (slow) -0.00512612
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -0.00512549
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00512464
VEGFC vascular endothelial growth factor C -0.00512201
ADGRE2 adhesion G protein-coupled receptor E2 -0.00511237
BRD2 bromodomain containing 2 -0.00510074
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00510013
LGALS8 lectin, galactoside-binding, soluble, 8 -0.00508285
SH3BP4 SH3-domain binding protein 4 -0.00507776
RBPMS RNA binding protein with multiple splicing -0.0050768
LMNA lamin A/C -0.00506656
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -0.00505596
MEA1 male-enhanced antigen 1 -0.00505515
CFI complement factor I -0.00504951
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.00504179
EFNB2 ephrin-B2 -0.00503899
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00503178
CRYM crystallin, mu -0.0050291
EIF3G eukaryotic translation initiation factor 3, subunit G -0.00502713
VEGFA vascular endothelial growth factor A -0.00502297
GADD45G growth arrest and DNA-damage-inducible, gamma -0.00501614
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00501547
GAB2 GRB2-associated binding protein 2 -0.00501025
IL6 interleukin 6 -0.00501013
GLUL glutamate-ammonia ligase -0.00500624
TGFBI transforming growth factor, beta-induced, 68kDa -0.0049982
DDIT3 DNA-damage-inducible transcript 3 -0.00499305
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00499134
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00498187
ARPP21 cAMP-regulated phosphoprotein, 21kDa -0.00498025
SOX17 SRY (sex determining region Y)-box 17 -0.00495461
IPCEF1 interaction protein for cytohesin exchange factors 1 -0.00495264
RB1 retinoblastoma 1 -0.00495171
IGHMBP2 immunoglobulin mu binding protein 2 -0.0049507
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.0049455
PCGF1 polycomb group ring finger 1 -0.00493906
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.00493219
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.00493183
GPI glucose-6-phosphate isomerase -0.00491728
SP100 SP100 nuclear antigen -0.00491592
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00491358
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.0049134
FXR2 fragile X mental retardation, autosomal homolog 2 -0.00491055
TMBIM1 transmembrane BAX inhibitor motif containing 1 -0.00489981
TMEM259 transmembrane protein 259 -0.00488752
CIAO2B cytosolic iron-sulfur assembly component 2B -0.00488412
LY6E lymphocyte antigen 6 complex, locus E -0.00488342
SMAD7 SMAD family member 7 -0.00488078
TECR trans-2,3-enoyl-CoA reductase -0.00487981
TSC22D3 TSC22 domain family, member 3 -0.00487608
FN1 fibronectin 1 -0.0048686
SLIT2 slit homolog 2 (Drosophila) -0.00486546