| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | thymic stromal lymphopoietin|This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 85480) |
| External Link | https://ncbi.nlm.nih.gov/gene/85480 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the TSLP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.022887 |
| DAPK1 | death-associated protein kinase 1 | 0.0119909 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.01198 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0114751 |
| MMP1 | matrix metallopeptidase 1 | 0.0113171 |
| ACKR3 | atypical chemokine receptor 3 | 0.0111839 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0110624 |
| NRCAM | neuronal cell adhesion molecule | 0.0101233 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0100851 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.009798 |
| TNS3 | tensin 3 | 0.00973212 |
| GPM6B | glycoprotein M6B | 0.00949828 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00929249 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00919105 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00913011 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00887108 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00886333 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00855704 |
| CLEC2B | C-type lectin domain family 2, member B | 0.0085569 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00848619 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00841527 |
| AGR2 | anterior gradient 2 | 0.00840564 |
| HMG20B | high mobility group 20B | 0.00829486 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00825616 |
| PTCH1 | patched 1 | 0.00824407 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00823792 |
| EPHB2 | EPH receptor B2 | 0.00820423 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00816833 |
| PPAP2A | phosphatidic acid phosphatase type 2A | 0.00816678 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00815998 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00814642 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00814382 |
| DACH1 | dachshund family transcription factor 1 | 0.00810304 |
| TAC1 | tachykinin, precursor 1 | 0.00805009 |
| EDNRB | endothelin receptor type B | 0.00802165 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00791277 |
| MYOF | myoferlin | 0.00790785 |
| TMEM176B | transmembrane protein 176B | 0.00787368 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00785491 |
| CADM1 | cell adhesion molecule 1 | 0.00784205 |
| LAMA4 | laminin, alpha 4 | 0.00782738 |
| NID1 | nidogen 1 | 0.00781983 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00780488 |
| MSX1 | msh homeobox 1 | 0.00775389 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00768611 |
| SETBP1 | SET binding protein 1 | 0.00767513 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00767107 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00766517 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00766422 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00760737 |
| COL3A1 | collagen, type III, alpha 1 | 0.00751729 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00750087 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00749079 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00747458 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00743622 |
| DCLK1 | doublecortin-like kinase 1 | 0.00740113 |
| MXRA5 | matrix-remodelling associated 5 | 0.00737415 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00735999 |
| SETD5 | SET domain containing 5 | 0.00734257 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00733366 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00732655 |
| SASH1 | SAM and SH3 domain containing 1 | 0.00727298 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00724134 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0072285 |
| XIC | X chromosome inactivation center | 0.00721458 |
| STON1 | stonin 1 | 0.00720977 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00720111 |
| MID1 | midline 1 | 0.00716945 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00712069 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | 0.00711307 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00710818 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00702522 |
| DMD | dystrophin | 0.00702059 |
| SCRIB | scribbled planar cell polarity protein | 0.00700661 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00699758 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00691325 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00691189 |
| GOLGA8H | golgin A8 family, member H | 0.00690799 |
| MYO1D | myosin ID | 0.00688891 |
| COLEC12 | collectin sub-family member 12 | 0.00686391 |
| VWF | von Willebrand factor | 0.00683319 |
| HELLS | helicase, lymphoid-specific | 0.00681028 |
| CD93 | CD93 molecule | 0.00679302 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00677597 |
| CHEK2 | checkpoint kinase 2 | 0.00676935 |
| TPD52 | tumor protein D52 | 0.00676671 |
| MGLL | monoglyceride lipase | 0.00674463 |
| TBX3 | T-box 3 | 0.00670571 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00667985 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00664262 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00664192 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00662599 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00661612 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00657709 |
| PCDH17 | protocadherin 17 | 0.00655964 |
| MLPH | melanophilin | 0.00648326 |
| MYO5C | myosin VC | 0.00647859 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00646732 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | 0.00642317 |
| COL21A1 | collagen, type XXI, alpha 1 | 0.0064122 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.00640172 |
| PLCE1 | phospholipase C, epsilon 1 | 0.00638487 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00637545 |
| TMEM47 | transmembrane protein 47 | 0.00636988 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00634786 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.00634367 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00632528 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0063248 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00632375 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00629996 |
| COPA | coatomer protein complex, subunit alpha | 0.0062937 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | 0.00628888 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00627681 |
| SNX7 | sorting nexin 7 | 0.00626704 |
| RXRA | retinoid X receptor, alpha | 0.00625557 |
| FOXF1 | forkhead box F1 | 0.00625004 |
| EFNB2 | ephrin-B2 | 0.00621551 |
| IRS2 | insulin receptor substrate 2 | 0.00620582 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00619579 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.00619239 |
| MX2 | MX dynamin-like GTPase 2 | 0.0061805 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00617028 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00615173 |
| DROSHA | drosha, ribonuclease type III | 0.00613508 |
| FCGBP | Fc fragment of IgG binding protein | 0.00612795 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00612037 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00611053 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00609996 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.00609868 |
| SDHAP1 | succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 | 0.00608596 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00606474 |
| GPM6A | glycoprotein M6A | 0.00605943 |
| CES3 | carboxylesterase 3 | 0.00603541 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00602301 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00601293 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.00600831 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00600391 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.00600371 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.00600262 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00600262 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00599556 |
| IFI44L | interferon-induced protein 44-like | 0.0059955 |
| GLA | galactosidase, alpha | 0.00597659 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0059744 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00597379 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00594726 |
| OLFML2A | olfactomedin-like 2A | 0.00594495 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00591526 |
| RRBP1 | ribosome binding protein 1 | 0.00590295 |
| PFKL | phosphofructokinase, liver | 0.00589558 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00589463 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.00589289 |
| QKI | QKI, KH domain containing, RNA binding | 0.00589176 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00588244 |
| EGR3 | early growth response 3 | 0.00585565 |
| KDR | kinase insert domain receptor | 0.00585259 |
| FRY | furry homolog (Drosophila) | 0.00585002 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | 0.00583735 |
| VCP | valosin containing protein | 0.00583729 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00580346 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0057995 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00579214 |
| KIAA0930 | KIAA0930 | 0.00578643 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.00578455 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00577361 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00575595 |
| BCHE | butyrylcholinesterase | 0.0057406 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00573939 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00573671 |
| RBPMS | RNA binding protein with multiple splicing | 0.00571241 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00568948 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00568648 |
| DST | dystonin | 0.00568369 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 0.00568266 |
| TPBG | trophoblast glycoprotein | 0.00567344 |
| RCAN2 | regulator of calcineurin 2 | 0.00566064 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00565896 |
| RALBP1 | ralA binding protein 1 | 0.00565616 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00565046 |
| NEK9 | NIMA-related kinase 9 | 0.00565022 |
| EGR1 | early growth response 1 | 0.00562457 |
| FN1 | fibronectin 1 | 0.00561995 |
| PNN | pinin, desmosome associated protein | 0.00559852 |
| MMP3 | matrix metallopeptidase 3 | 0.0055881 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00558421 |
| SNX1 | sorting nexin 1 | 0.00557498 |
| CP | ceruloplasmin (ferroxidase) | 0.00557494 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0055618 |
| ITGA6 | integrin, alpha 6 | 0.00555829 |
| KMT5B | lysine methyltransferase 5B | 0.00555092 |
| ADAR | adenosine deaminase, RNA-specific | 0.00553663 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00552201 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00551936 |
| RBM6 | RNA binding motif protein 6 | 0.00551899 |
| FBLN2 | fibulin 2 | 0.00550208 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00549985 |
| ZNF638 | zinc finger protein 638 | 0.00549786 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00549198 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.00547096 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00546131 |
| EMC2 | ER membrane protein complex subunit 2 | 0.00545771 |
| BRD4 | bromodomain containing 4 | 0.00543737 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.00543432 |
| A2M | alpha-2-macroglobulin | 0.00543042 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00541345 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0054011 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00539722 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.00538685 |
| CALCA | calcitonin-related polypeptide alpha | 0.00537673 |
| CCN2 | cellular communication network factor 2 | 0.0053541 |
| HMGB3 | high mobility group box 3 | 0.00534936 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00533443 |
| PDCD6 | programmed cell death 6 | 0.00532633 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.00532277 |
| MATN2 | matrilin 2 | 0.00532079 |
| COL4A1 | collagen, type IV, alpha 1 | 0.00531766 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00530985 |
| APOD | apolipoprotein D | 0.005306 |
| FLT1 | fms-related tyrosine kinase 1 | 0.00530275 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00530019 |
| PRDX1 | peroxiredoxin 1 | 0.0052931 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00527581 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00526412 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0052334 |
| MRPS28 | mitochondrial ribosomal protein S28 | 0.00521347 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00521301 |
| CHP2 | calcineurin-like EF-hand protein 2 | 0.0052047 |
| PDGFD | platelet derived growth factor D | 0.00519229 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00518685 |
| NOTCH2NL | notch 2 N-terminal like | 0.00517731 |
| EGR2 | early growth response 2 | 0.0051745 |
| PUM1 | pumilio RNA-binding family member 1 | 0.00516762 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.00514054 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00513687 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0051314 |
| TKTL1 | transketolase-like 1 | 0.00512865 |
| INHBB | inhibin, beta B | 0.00512609 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.0051237 |
| PROCR | protein C receptor, endothelial | 0.00512128 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00512068 |
| IGF2R | insulin-like growth factor 2 receptor | 0.00510788 |
| HOXB6 | homeobox B6 | 0.00510283 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00509272 |
| TXN | thioredoxin | 0.00506961 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 | 0.00506932 |
| JAM3 | junctional adhesion molecule 3 | 0.0050676 |
| PALMD | palmdelphin | 0.00505378 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00505093 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00503531 |
| SELE | selectin E | 0.00502371 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | -0.0224477 |
| S100A9 | S100 calcium binding protein A9 | -0.0207266 |
| S100A8 | S100 calcium binding protein A8 | -0.0193128 |
| CSTA | cystatin A (stefin A) | -0.0160729 |
| LCN2 | lipocalin 2 | -0.0141178 |
| HBD | hemoglobin, delta | -0.0126805 |
| MXRA7 | matrix-remodelling associated 7 | -0.0114539 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0112951 |
| LYZ | lysozyme | -0.0112124 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.0111146 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.010855 |
| KRT19 | keratin 19, type I | -0.0107587 |
| S100A12 | S100 calcium binding protein A12 | -0.0103599 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.0102127 |
| RGS4 | regulator of G-protein signaling 4 | -0.0101463 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.010008 |
| NIBAN1 | niban apoptosis regulator 1 | -0.010007 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00973948 |
| IL7R | interleukin 7 receptor | -0.00946882 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00934433 |
| S100P | S100 calcium binding protein P | -0.00931556 |
| CST7 | cystatin F (leukocystatin) | -0.0091444 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00911778 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00907415 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00904754 |
| JMJD6 | jumonji domain containing 6 | -0.00903321 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00897906 |
| MMP9 | matrix metallopeptidase 9 | -0.00894481 |
| MPO | myeloperoxidase | -0.00893319 |
| CD52 | CD52 molecule | -0.00890155 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00888804 |
| TARP | TCR gamma alternate reading frame protein | -0.0088865 |
| BPI | bactericidal/permeability-increasing protein | -0.00881359 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00881007 |
| FST | follistatin | -0.00880147 |
| BCL2A1 | BCL2-related protein A1 | -0.00864866 |
| ANXA3 | annexin A3 | -0.00853806 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.00852061 |
| ELANE | elastase, neutrophil expressed | -0.00849822 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00849269 |
| TPM4 | tropomyosin 4 | -0.00834653 |
| KRT13 | keratin 13, type I | -0.00834083 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00829057 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0082016 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.00819882 |
| ANXA1 | annexin A1 | -0.00816903 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00803652 |
| RGS10 | regulator of G-protein signaling 10 | -0.00797519 |
| MAL | mal, T-cell differentiation protein | -0.00784853 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.0078363 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00779013 |
| PYCARD | PYD and CARD domain containing | -0.0077873 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00778555 |
| CAMP | cathelicidin antimicrobial peptide | -0.00776074 |
| PITX3 | paired-like homeodomain 3 | -0.00775379 |
| TSPYL5 | TSPY-like 5 | -0.0077488 |
| EAPP | E2F-associated phosphoprotein | -0.00773077 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00771659 |
| KRT5 | keratin 5, type II | -0.00771092 |
| KRT15 | keratin 15, type I | -0.00769539 |
| IL1RN | interleukin 1 receptor antagonist | -0.00769163 |
| CLIC3 | chloride intracellular channel 3 | -0.00763535 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00762623 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00760872 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00759259 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00751643 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00734601 |
| CD2 | CD2 molecule | -0.0073079 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00730661 |
| IL2RG | interleukin 2 receptor, gamma | -0.00730061 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00725019 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00724895 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00724631 |
| AZU1 | azurocidin 1 | -0.00724327 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00719836 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00717692 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00716612 |
| AHSG | alpha-2-HS-glycoprotein | -0.0071453 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00707811 |
| TPD52L1 | tumor protein D52-like 1 | -0.00703813 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00701481 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.0069899 |
| SPRR3 | small proline-rich protein 3 | -0.00698415 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00697117 |
| CTSG | cathepsin G | -0.00691385 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00688429 |
| ARG1 | arginase 1 | -0.00684344 |
| TGFA | transforming growth factor, alpha | -0.00683929 |
| DEFB1 | defensin, beta 1 | -0.00682806 |
| LXN | latexin | -0.00681019 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00674759 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00674031 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00673527 |
| FPR1 | formyl peptide receptor 1 | -0.00672858 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.0067181 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00668436 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00667959 |
| DCK | deoxycytidine kinase | -0.00664957 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -0.00664579 |
| PGLYRP1 | peptidoglycan recognition protein 1 | -0.0066158 |
| ASGR2 | asialoglycoprotein receptor 2 | -0.00658548 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0065854 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00651777 |
| CTSW | cathepsin W | -0.00650623 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00648512 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.00647955 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00646224 |
| C5AR1 | complement component 5a receptor 1 | -0.00644084 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00641289 |
| CDK14 | cyclin-dependent kinase 14 | -0.00639755 |
| INHBA | inhibin, beta A | -0.00637514 |
| METTL7A | methyltransferase like 7A | -0.00637404 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | -0.00636653 |
| SELENBP1 | selenium binding protein 1 | -0.00635073 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00632695 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0062238 |
| PF4 | platelet factor 4 | -0.00622105 |
| MMP8 | matrix metallopeptidase 8 | -0.00621373 |
| GUCY2C | guanylate cyclase 2C | -0.00621228 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00618553 |
| PDGFC | platelet derived growth factor C | -0.00617588 |
| PITX1 | paired-like homeodomain 1 | -0.00615504 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00614329 |
| MPC1 | mitochondrial pyruvate carrier 1 | -0.00612856 |
| VPREB3 | pre-B lymphocyte 3 | -0.00606299 |
| RWDD2B | RWD domain containing 2B | -0.00606156 |
| HTRA1 | HtrA serine peptidase 1 | -0.00606138 |
| TGFB1 | transforming growth factor, beta 1 | -0.00604389 |
| G0S2 | G0/G1 switch 2 | -0.00603543 |
| PADI4 | peptidyl arginine deiminase, type IV | -0.00603463 |
| MGAM | maltase-glucoamylase | -0.00602422 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00601644 |
| RPA3 | replication protein A3, 14kDa | -0.00595953 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00593012 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00591028 |
| FOLR1 | folate receptor 1 (adult) | -0.00589555 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00589068 |
| KLHL2 | kelch-like family member 2 | -0.00586905 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00585839 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00585473 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00585343 |
| LST1 | leukocyte specific transcript 1 | -0.00584495 |
| SIRT3 | sirtuin 3 | -0.00583034 |
| PRKCA | protein kinase C, alpha | -0.00582539 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.00579368 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00579367 |
| ILK | integrin-linked kinase | -0.00577766 |
| FYB1 | FYN binding protein 1 | -0.00575743 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 | -0.00573591 |
| SPRR1A | small proline-rich protein 1A | -0.00573163 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -0.00573116 |
| RETN | resistin | -0.00573043 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00572932 |
| PRSS8 | protease, serine, 8 | -0.00569205 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0056893 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00564847 |
| CHIT1 | chitinase 1 (chitotriosidase) | -0.00564808 |
| SDC1 | syndecan 1 | -0.00564297 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00563334 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00562111 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.00560449 |
| ORM1 | orosomucoid 1 | -0.00559895 |
| UROD | uroporphyrinogen decarboxylase | -0.00559441 |
| EVI2A | ecotropic viral integration site 2A | -0.0055867 |
| IPO13 | importin 13 | -0.00558327 |
| AK1 | adenylate kinase 1 | -0.00556142 |
| SRPRB | signal recognition particle receptor, B subunit | -0.0055575 |
| BLVRB | biliverdin reductase B | -0.00555398 |
| SVIL | supervillin | -0.0055487 |
| ZNF652 | zinc finger protein 652 | -0.00554632 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -0.00552343 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -0.00551812 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00551554 |
| TPM2 | tropomyosin 2 (beta) | -0.00550821 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0054976 |
| PSPH | phosphoserine phosphatase | -0.00548777 |
| SNX6 | sorting nexin 6 | -0.00548391 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00548169 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00546658 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00546583 |
| GPSM3 | G-protein signaling modulator 3 | -0.0054206 |
| HBZ | hemoglobin, zeta | -0.00541672 |
| DOK5 | docking protein 5 | -0.00540384 |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) | -0.00539843 |
| NFE2 | nuclear factor, erythroid 2 | -0.00537721 |
| EPB42 | erythrocyte membrane protein band 4.2 | -0.00535458 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00533998 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00533665 |
| GPR65 | G protein-coupled receptor 65 | -0.00532358 |
| FAM46C | family with sequence similarity 46, member C | -0.00532093 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00531406 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00530092 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.00528583 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00527506 |
| ERCC1 | excision repair cross-complementation group 1 | -0.00525449 |
| CDC42 | cell division cycle 42 | -0.00525143 |
| TESC | tescalcin | -0.00524866 |
| DERL2 | derlin 2 | -0.00523418 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00522661 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00522532 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -0.00522491 |
| BUD31 | BUD31 homolog (S. cerevisiae) | -0.00521399 |
| CD27 | CD27 molecule | -0.00520484 |
| GLUL | glutamate-ammonia ligase | -0.00519361 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00518176 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00518131 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | -0.00516355 |
| HAMP | hepcidin antimicrobial peptide | -0.00513358 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00513045 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00511134 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00511055 |
| GYG1 | glycogenin 1 | -0.00508925 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00508764 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00507191 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | -0.00505677 |
| IL18RAP | interleukin 18 receptor accessory protein | -0.00504642 |
| KLF1 | Kruppel-like factor 1 (erythroid) | -0.00504507 |
| NKX3-1 | NK3 homeobox 1 | -0.00504473 |
| EHD1 | EH-domain containing 1 | -0.00504288 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00504238 |
| CLEC4A | C-type lectin domain family 4, member A | -0.00504173 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00502442 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0050125 |
| SMAGP | small cell adhesion glycoprotein | -0.00500676 |
| S100A7 | S100 calcium binding protein A7 | -0.00500168 |
| OAZ3 | ornithine decarboxylase antizyme 3 | -0.00499009 |
| AFP | alpha-fetoprotein | -0.00497601 |
| AREG | amphiregulin | -0.00496713 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00496179 |
| ALB | albumin | -0.00495219 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00494201 |
| SIX2 | SIX homeobox 2 | -0.00494144 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00494107 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00493025 |
| SMYD2 | SET and MYND domain containing 2 | -0.00491981 |
| PRTN3 | proteinase 3 | -0.00489779 |
| MRPS10 | mitochondrial ribosomal protein S10 | -0.00489319 |
| CLC | Charcot-Leyden crystal galectin | -0.00488967 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00488103 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00487782 |
| VEGFA | vascular endothelial growth factor A | -0.00487734 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00487712 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.00487417 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00487182 |
| ADI1 | acireductone dioxygenase 1 | -0.00485945 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00485883 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.00484899 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | -0.00483542 |
| LIMD2 | LIM domain containing 2 | -0.00483534 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00483416 |
