TSPO Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description translocator protein (18kDa)|Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012] (NCBI Entrez Gene Database, 706)
External Link https://ncbi.nlm.nih.gov/gene/706
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Genes

471 genes differentially expressed following the TSPO gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HSPB1 heat shock 27kDa protein 1 0.0226978
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.015187
CCN2 cellular communication network factor 2 0.0132972
AKAP12 A kinase (PRKA) anchor protein 12 0.0126585
HOPX HOP homeobox 0.0125413
DAPK1 death-associated protein kinase 1 0.0121458
TM4SF1 transmembrane 4 L six family member 1 0.0119639
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.0119312
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.0111443
XIC X chromosome inactivation center 0.0109858
ARID4A AT rich interactive domain 4A (RBP1-like) 0.010948
AUTS2 autism susceptibility candidate 2 0.0109125
LMO3 LIM domain only 3 (rhombotin-like 2) 0.0109093
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.0107038
SCD5 stearoyl-CoA desaturase 5 0.010672
GIMAP6 GTPase, IMAP family member 6 0.0105818
SPRR1B small proline-rich protein 1B 0.0104718
FABP1 fatty acid binding protein 1, liver 0.0104318
KRT20 keratin 20, type I 0.0104236
CLEC2B C-type lectin domain family 2, member B 0.010304
DIPK1A divergent protein kinase domain 1A 0.0102995
GPA33 glycoprotein A33 (transmembrane) 0.0102604
OPHN1 oligophrenin 1 0.0101283
SPON1 spondin 1, extracellular matrix protein 0.0101195
CLIC5 chloride intracellular channel 5 0.0101049
LY96 lymphocyte antigen 96 0.0100189
TSPYL5 TSPY-like 5 0.0100155
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00999594
LPIN1 lipin 1 0.00995038
MEF2C myocyte enhancer factor 2C 0.0098995
KLK5 kallikrein-related peptidase 5 0.00987437
CXADR coxsackie virus and adenovirus receptor 0.00982803
LAMP3 lysosomal-associated membrane protein 3 0.00980458
BMP7 bone morphogenetic protein 7 0.00979709
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00971691
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.00970033
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00968723
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00967417
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00963902
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00959156
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00954004
LRP4 low density lipoprotein receptor-related protein 4 0.00947679
LAPTM4B lysosomal protein transmembrane 4 beta 0.00936849
TYRP1 tyrosinase-related protein 1 0.00931765
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00925141
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00925133
PROM1 prominin 1 0.00924931
MAB21L2 mab-21-like 2 (C. elegans) 0.00923783
IL13RA2 interleukin 13 receptor, alpha 2 0.009229
DOK5 docking protein 5 0.00917316
AQP3 aquaporin 3 (Gill blood group) 0.00909188
CPVL carboxypeptidase, vitellogenic-like 0.00901986
VSIG4 V-set and immunoglobulin domain containing 4 0.00896598
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00894358
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.0088404
S100A8 S100 calcium binding protein A8 0.00883217
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00878114
CD59 CD59 molecule, complement regulatory protein 0.00876998
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00866901
DUSP5 dual specificity phosphatase 5 0.00866866
RGCC regulator of cell cycle 0.00864729
AMDHD2 amidohydrolase domain containing 2 0.00864703
CEMIP cell migration inducing protein, hyaluronan binding 0.00859426
CRABP2 cellular retinoic acid binding protein 2 0.00859282
FCGBP Fc fragment of IgG binding protein 0.00858515
S100A9 S100 calcium binding protein A9 0.00853511
DCN decorin 0.00850609
MYH10 myosin, heavy chain 10, non-muscle 0.00850455
TOX thymocyte selection-associated high mobility group box 0.00845434
KRT1 keratin 1, type II 0.00841283
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00837437
BEX4 brain expressed, X-linked 4 0.00835401
PI3 peptidase inhibitor 3, skin-derived 0.00833356
CXCL8 chemokine (C-X-C motif) ligand 8 0.0083108
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00828191
PEG3 paternally expressed 3 0.00827133
IGFBP5 insulin-like growth factor binding protein 5 0.00816647
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.00816041
PELI1 pellino E3 ubiquitin protein ligase 1 0.00805919
RHOC ras homolog family member C 0.00804659
TP53I3 tumor protein p53 inducible protein 3 0.00802174
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00799541
MCL1 myeloid cell leukemia 1 0.00797916
APOLD1 apolipoprotein L domain containing 1 0.00797622
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.00795769
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00794246
RGS1 regulator of G-protein signaling 1 0.00790926
ICAM2 intercellular adhesion molecule 2 0.00789578
TCTN2 tectonic family member 2 0.00783085
CD200 CD200 molecule 0.00780484
SFRP4 secreted frizzled-related protein 4 0.00780305
ATP10B ATPase, class V, type 10B 0.00777806
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00777633
CFI complement factor I 0.00777437
SMAGP small cell adhesion glycoprotein 0.00772831
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00772133
SOX11 SRY (sex determining region Y)-box 11 0.00771
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.007643
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00762549
BEX1 brain expressed, X-linked 1 0.0076198
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00761814
KLK10 kallikrein-related peptidase 10 0.0075294
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.00749935
DOCK4 dedicator of cytokinesis 4 0.00749895
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00748632
EDN3 endothelin 3 0.00746432
F2R coagulation factor II (thrombin) receptor 0.00745092
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.00744749
KLF6 Kruppel-like factor 6 0.00743365
MTUS1 microtubule associated tumor suppressor 1 0.00743226
PRDX4 peroxiredoxin 4 0.00741762
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00741539
GIMAP4 GTPase, IMAP family member 4 0.00736539
GSTA4 glutathione S-transferase alpha 4 0.00735702
MYO5A myosin VA (heavy chain 12, myoxin) 0.00735087
ADM adrenomedullin 0.00734805
PON2 paraoxonase 2 0.00733693
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00732876
RCAN1 regulator of calcineurin 1 0.00732786
PLAU plasminogen activator, urokinase 0.00730226
TSC22D2 TSC22 domain family, member 2 0.00728404
S100A7 S100 calcium binding protein A7 0.00728103
SFRP1 secreted frizzled-related protein 1 0.00725567
HSPA1A heat shock 70kDa protein 1A 0.00725475
CIAO3 cytosolic iron-sulfur assembly component 3 0.00725085
KLF4 Kruppel-like factor 4 (gut) 0.00725005
WWTR1 WW domain containing transcription regulator 1 0.00724863
GNAS GNAS complex locus 0.00723482
LGALS4 lectin, galactoside-binding, soluble, 4 0.00720128
IFI27 interferon, alpha-inducible protein 27 0.00718354
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00717437
C1ORF115 chromosome 1 open reading frame 115 0.00717376
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00717344
AHNAK AHNAK nucleoprotein 0.00708115
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00707819
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00704737
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 0.00703923
NDN necdin, melanoma antigen (MAGE) family member 0.00703497
RHOB ras homolog family member B 0.00701716
SGCE sarcoglycan, epsilon 0.00701054
SYNE1 spectrin repeat containing, nuclear envelope 1 0.00700915
IFITM2 interferon induced transmembrane protein 2 0.0070066
SCEL sciellin 0.00700651
TSPAN7 tetraspanin 7 0.00699286
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.00699286
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00698928
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00698873
FNBP1 formin binding protein 1 0.00698794
SIRT3 sirtuin 3 0.00696518
NEBL nebulette 0.00693014
CD34 CD34 molecule 0.00692221
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00689516
ACP6 acid phosphatase 6, lysophosphatidic 0.00688823
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00687921
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 0.0068292
CCNA2 cyclin A2 0.00681513
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00680532
PRKCB protein kinase C, beta 0.00680415
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00680335
SPP1 secreted phosphoprotein 1 0.00679046
ASS1 argininosuccinate synthase 1 0.0067844
VNN1 vanin 1 0.00677726
TMEM100 transmembrane protein 100 0.00675236
NOX1 NADPH oxidase 1 0.00674608
PALLD palladin, cytoskeletal associated protein 0.00670966
GUSBP3 glucuronidase, beta pseudogene 3 0.00670524
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00669978
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00669946
DEFB1 defensin, beta 1 0.00669483
IER5 immediate early response 5 0.00669366
PLK2 polo-like kinase 2 0.00667969
ISG20 interferon stimulated exonuclease gene 20kDa 0.00667889
POU2AF1 POU class 2 associating factor 1 0.00667728
NRN1 neuritin 1 0.00667085
ADI1 acireductone dioxygenase 1 0.00666028
PDZK1IP1 PDZK1 interacting protein 1 0.00663967
FKBP11 FK506 binding protein 11, 19 kDa 0.00663642
EFNA1 ephrin-A1 0.00662482
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00662239
SCGB2A2 secretoglobin, family 2A, member 2 0.00662007
OPN3 opsin 3 0.00661275
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00661262
CCNG1 cyclin G1 0.00660104
CD53 CD53 molecule 0.00658884
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0065856
MALL mal, T-cell differentiation protein-like 0.00658312
ADAT1 adenosine deaminase, tRNA-specific 1 0.00657154
RRAGD Ras-related GTP binding D 0.00651988
UPP1 uridine phosphorylase 1 0.00651225
KIAA0125 KIAA0125 0.00650457
DSG3 desmoglein 3 0.00649992
EIF5 eukaryotic translation initiation factor 5 0.00649573
ARL4A ADP-ribosylation factor-like 4A 0.00649206
C1QB complement component 1, q subcomponent, B chain 0.00647183
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00646331
PNMA2 paraneoplastic Ma antigen 2 0.00645668
POU4F1 POU class 4 homeobox 1 0.00645064
GPR137B G protein-coupled receptor 137B 0.00643651
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00643454
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00642469
SPRR1A small proline-rich protein 1A 0.00641951
FGFBP1 fibroblast growth factor binding protein 1 0.0064185
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00640468
XPO7 exportin 7 0.00640177
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00639037
LY6D lymphocyte antigen 6 complex, locus D 0.00638146
MYO1B myosin IB 0.00637224
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00635717
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00634861
INAVA innate immunity activator 0.00634619
MDK midkine (neurite growth-promoting factor 2) 0.0063437
KLF7 Kruppel-like factor 7 (ubiquitous) 0.00633646
ZHX2 zinc fingers and homeoboxes 2 0.00631219
PDE4B phosphodiesterase 4B, cAMP-specific 0.0063091
ATXN1 ataxin 1 0.00628995
ANXA1 annexin A1 0.00627093
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00625797
CD163 CD163 molecule 0.00623062
FAR2 fatty acyl CoA reductase 2 0.00622406
CA12 carbonic anhydrase XII 0.00620548
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00618602
MEP1A meprin A, alpha (PABA peptide hydrolase) 0.00617456
CD96 CD96 molecule 0.0061712
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00617011
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00614751
HMOX1 heme oxygenase 1 0.00614545
CD99 CD99 molecule 0.00613857
ECM1 extracellular matrix protein 1 0.00613768
ATP5PD ATP synthase peripheral stalk subunit d 0.0061282
C1QA complement component 1, q subcomponent, A chain 0.00611228
ZNF395 zinc finger protein 395 0.00610556
PNMA1 paraneoplastic Ma antigen 1 0.00609859
CHP1 calcineurin-like EF-hand protein 1 0.00609221
SETD5 SET domain containing 5 0.00609105
ATF3 activating transcription factor 3 0.00607441
GAS6 growth arrest-specific 6 0.00606332
EMX2 empty spiracles homeobox 2 0.00606052
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00603076
DYNLL1 dynein, light chain, LC8-type 1 0.00602132
MERTK MER proto-oncogene, tyrosine kinase 0.00601089
EMP1 epithelial membrane protein 1 0.00599418
RBM34 RNA binding motif protein 34 0.00599337
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 0.00598404
TRIM29 tripartite motif containing 29 0.00597936
DAD1 defender against cell death 1 0.00595678

decreased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.023876
PCNA proliferating cell nuclear antigen -0.0180425
LYZ lysozyme -0.0157472
MMP1 matrix metallopeptidase 1 -0.0144771
NEFH neurofilament, heavy polypeptide -0.0141706
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0140249
S100P S100 calcium binding protein P -0.0124288
RNF167 ring finger protein 167 -0.0121917
MSMB microseminoprotein, beta- -0.0121377
CD9 CD9 molecule -0.0121314
CCNB1 cyclin B1 -0.0120969
CNPY3 canopy FGF signaling regulator 3 -0.0117514
KRT19 keratin 19, type I -0.011484
IGF1 insulin-like growth factor 1 (somatomedin C) -0.0113854
TFF1 trefoil factor 1 -0.0107887
GSTM3 glutathione S-transferase mu 3 (brain) -0.0107416
LUM lumican -0.0107168
HK2 hexokinase 2 -0.0106694
TGFBI transforming growth factor, beta-induced, 68kDa -0.0105367
TACSTD2 tumor-associated calcium signal transducer 2 -0.0100813
EGR2 early growth response 2 -0.0100718
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.0100473
AGR2 anterior gradient 2 -0.00998418
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00995855
MLPH melanophilin -0.00993243
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.0097244
SORD sorbitol dehydrogenase -0.00938963
G0S2 G0/G1 switch 2 -0.00935504
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00932786
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00920051
RTN1 reticulon 1 -0.00919882
PLCB4 phospholipase C, beta 4 -0.0091705
NIBAN1 niban apoptosis regulator 1 -0.00908877
RCAN2 regulator of calcineurin 2 -0.00906368
PLD3 phospholipase D family, member 3 -0.00905805
TXNDC9 thioredoxin domain containing 9 -0.00904365
MMP7 matrix metallopeptidase 7 -0.00899029
MOK MOK protein kinase -0.00887841
CFD complement factor D (adipsin) -0.00864794
LMNB1 lamin B1 -0.00862085
MAOA monoamine oxidase A -0.00860523
SLC44A4 solute carrier family 44, member 4 -0.00851344
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00850083
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.00848167
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -0.00844387
GPX2 glutathione peroxidase 2 -0.00843816
BASP1 brain abundant, membrane attached signal protein 1 -0.00839764
PHACTR2 phosphatase and actin regulator 2 -0.00836018
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00835303
PCP4 Purkinje cell protein 4 -0.00834515
FRS2 fibroblast growth factor receptor substrate 2 -0.00830911
IL10RA interleukin 10 receptor, alpha -0.00830389
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00828787
TFF3 trefoil factor 3 (intestinal) -0.00828387
FGL2 fibrinogen-like 2 -0.00816183
OLFM4 olfactomedin 4 -0.00815722
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00815045
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00805107
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00799983
ZBTB18 zinc finger and BTB domain containing 18 -0.00797534
PF4 platelet factor 4 -0.00796721
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00796532
AOX1 aldehyde oxidase 1 -0.00795486
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00791993
S100A4 S100 calcium binding protein A4 -0.00791858
GPX3 glutathione peroxidase 3 -0.00786847
COL4A5 collagen, type IV, alpha 5 -0.00785072
PDLIM3 PDZ and LIM domain 3 -0.00782649
CST7 cystatin F (leukocystatin) -0.00779656
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0077621
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00773248
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00772861
CTSH cathepsin H -0.00769279
RRBP1 ribosome binding protein 1 -0.00768215
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00763707
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00761
MXRA5 matrix-remodelling associated 5 -0.00756984
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -0.0075615
SIDT2 SID1 transmembrane family, member 2 -0.00754879
SNAI2 snail family zinc finger 2 -0.00754878
PRPF4 pre-mRNA processing factor 4 -0.00753458
STK10 serine/threonine kinase 10 -0.0075164
KYNU kynureninase -0.00749107
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0074758
KRT7 keratin 7, type II -0.00746679
CYTH1 cytohesin 1 -0.00746065
MB myoglobin -0.00745059
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00744243
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -0.00739676
COL16A1 collagen, type XVI, alpha 1 -0.00738794
PMP22 peripheral myelin protein 22 -0.00737233
NTS neurotensin -0.00736391
PRSS21 protease, serine, 21 (testisin) -0.0073293
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.0072754
SLC38A1 solute carrier family 38, member 1 -0.00727287
SLC43A3 solute carrier family 43, member 3 -0.007243
SCG5 secretogranin V -0.00722654
ASPN asporin -0.0072082
IL7R interleukin 7 receptor -0.00720639
SOWAHC sosondowah ankyrin repeat domain family member C -0.00719306
NXN nucleoredoxin -0.00718569
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00716461
CHKB choline kinase beta -0.00715833
FOXC1 forkhead box C1 -0.00715181
PDGFRL platelet-derived growth factor receptor-like -0.00714095
CHGB chromogranin B -0.007139
GAS1 growth arrest-specific 1 -0.00713771
FBLN1 fibulin 1 -0.0071096
PRDX2 peroxiredoxin 2 -0.0071037
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00710361
TNNT1 troponin T type 1 (skeletal, slow) -0.00709672
WASL Wiskott-Aldrich syndrome-like -0.007094
GATA2 GATA binding protein 2 -0.00708745
SELENBP1 selenium binding protein 1 -0.00705945
COL14A1 collagen, type XIV, alpha 1 -0.0070465
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00698254
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00696833
NPY1R neuropeptide Y receptor Y1 -0.00695811
TMPRSS4 transmembrane protease, serine 4 -0.00693666
METRN meteorin, glial cell differentiation regulator -0.00692415
EMP3 epithelial membrane protein 3 -0.00690429
HMGN5 high mobility group nucleosome binding domain 5 -0.00689569
COL6A3 collagen, type VI, alpha 3 -0.00689247
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00684468
MBL2 mannose-binding lectin (protein C) 2, soluble -0.0068397
MPO myeloperoxidase -0.00683016
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00682135
TGFB1 transforming growth factor, beta 1 -0.00682104
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00679273
ADCY1 adenylate cyclase 1 (brain) -0.00678465
BICC1 BicC family RNA binding protein 1 -0.00678315
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00676676
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00676403
CCDC69 coiled-coil domain containing 69 -0.0067629
BTG2 BTG family, member 2 -0.00676015
RAP1GAP2 RAP1 GTPase activating protein 2 -0.00675684
TAGLN transgelin -0.0067101
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00670378
UBE2M ubiquitin-conjugating enzyme E2M -0.00669624
DPT dermatopontin -0.00669411
BTK Bruton agammaglobulinemia tyrosine kinase -0.0066863
VCAN versican -0.00666164
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00665781
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00665778
VEGFA vascular endothelial growth factor A -0.00664415
KRT13 keratin 13, type I -0.00663495
CHRDL1 chordin-like 1 -0.00662474
PRR7 proline rich 7 (synaptic) -0.00662284
TOB1 transducer of ERBB2, 1 -0.00661472
DACH1 dachshund family transcription factor 1 -0.00661194
SLC16A6 solute carrier family 16, member 6 -0.00660823
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00660217
PRB3 proline-rich protein BstNI subfamily 3 -0.00658119
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -0.00657081
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00656812
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.00654911
GNLY granulysin -0.00654829
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00654704
CST4 cystatin S -0.00652324
MTARC1 mitochondrial amidoxime reducing component 1 -0.00650787
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00649188
CBX6 chromobox homolog 6 -0.00647002
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00642542
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00642339
CRYM crystallin, mu -0.00641459
MEIS2 Meis homeobox 2 -0.00641405
OGN osteoglycin -0.00641129
NOTCH2 notch 2 -0.00639315
LAMA2 laminin, alpha 2 -0.00637243
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -0.00636952
MTCL1 microtubule crosslinking factor 1 -0.00636876
LTF lactotransferrin -0.00636037
KIAA0100 KIAA0100 -0.00635202
TFRC transferrin receptor -0.0063385
MAP7 microtubule-associated protein 7 -0.0063333
STATH statherin -0.00632319
GSDME gasdermin E -0.00632208
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00631441
PSCA prostate stem cell antigen -0.00628733
PLXNB2 plexin B2 -0.0062619
NBPF10 neuroblastoma breakpoint family, member 10 -0.00625406
CRIP2 cysteine-rich protein 2 -0.00624675
TMSB15A thymosin beta 15a -0.00623898
SRPX sushi-repeat containing protein, X-linked -0.00623867
COQ8A coenzyme Q8A -0.00620432
SV2B synaptic vesicle glycoprotein 2B -0.00620277
FLNA filamin A, alpha -0.00619749
NNMT nicotinamide N-methyltransferase -0.00618623
HIC2 hypermethylated in cancer 2 -0.00618466
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00615659
RGS10 regulator of G-protein signaling 10 -0.00615493
PTGES prostaglandin E synthase -0.00612661
DMBT1 deleted in malignant brain tumors 1 -0.00610357
INTS6 integrator complex subunit 6 -0.00608885
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00608338
CPM carboxypeptidase M -0.00605967
ARHGAP29 Rho GTPase activating protein 29 -0.00604025
SCPEP1 serine carboxypeptidase 1 -0.00603937
PLXNC1 plexin C1 -0.00603714
PTGIS prostaglandin I2 (prostacyclin) synthase -0.0060311
EDNRA endothelin receptor type A -0.00603103
C4BPB complement component 4 binding protein, beta -0.00603044
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.00601517
NELL2 NEL-like 2 (chicken) -0.00601317
TXLNA taxilin alpha -0.00600797
STEAP3 STEAP family member 3, metalloreductase -0.0059926
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00597833
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00597479
PLAAT3 phospholipase A and acyltransferase 3 -0.00596327
VAMP8 vesicle-associated membrane protein 8 -0.00595696
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.00594815
CNTN1 contactin 1 -0.00592552
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00589428
TYMP thymidine phosphorylase -0.00588525
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00588426
CCR1 chemokine (C-C motif) receptor 1 -0.00588188
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.0058721
ATAD2 ATPase family, AAA domain containing 2 -0.00586805
VIPR1 vasoactive intestinal peptide receptor 1 -0.00586451
OSR2 odd-skipped related transciption factor 2 -0.00585659
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00584722
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00584308
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00583653
ANXA6 annexin A6 -0.00583625
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00583174
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00581232