TSSC4 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description tumor suppressing subtransferable candidate 4|This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 10078)
External Link http://www.ncbi.nlm.nih.gov/gene/10078
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Genes

59 interacting proteins for TSSC4 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
APP amyloid beta (A4) precursor protein
AQR aquarius intron-binding spliceosomal factor
BCAS2 breast carcinoma amplified sequence 2
C9ORF78 chromosome 9 open reading frame 78
CCDC12 coiled-coil domain containing 12
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDC5L cell division cycle 5-like
CRNKL1 crooked neck pre-mRNA splicing factor 1
CWC15 CWC15 spliceosome-associated protein
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
EAPP E2F-associated phosphoprotein
ECD ecdysoneless homolog (Drosophila)
EFTUD2 elongation factor Tu GTP binding domain containing 2
ISY1 ISY1 splicing factor homolog (S. cerevisiae)
KPNA3 karyopherin alpha 3 (importin alpha 4)
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NCDN neurochondrin
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NRF1 nuclear respiratory factor 1
PAXBP1 PAX3 and PAX7 binding protein 1
PLRG1 pleiotropic regulator 1
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPIH peptidylprolyl isomerase H (cyclophilin H)
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PRPF19 pre-mRNA processing factor 19
PRPF31 pre-mRNA processing factor 31
PRPF6 pre-mRNA processing factor 6
PRPF8 pre-mRNA processing factor 8
RSRC1 arginine/serine-rich coiled-coil 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SART1 squamous cell carcinoma antigen recognized by T cells
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNRPG small nuclear ribonucleoprotein polypeptide G
SNW1 SNW domain containing 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SYF2 SYF2 pre-mRNA-splicing factor
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TERF2IP telomeric repeat binding factor 2, interacting protein
TFIP11 tuftelin interacting protein 11
TTC27 tetratricopeptide repeat domain 27
UBA1 ubiquitin-like modifier activating enzyme 1
UBC ubiquitin C
USP39 ubiquitin specific peptidase 39
WDR70 WD repeat domain 70
XAB2 XPA binding protein 2
ZNHIT2 zinc finger, HIT-type containing 2