TT Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
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Genes

404 gene knockdowns changing fitness of TT relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
NDOR1 NADPH dependent diflavin oxidoreductase 1 3.19303
PLAG1 pleiomorphic adenoma gene 1 3.19303
AQP3 aquaporin 3 (Gill blood group) 3.11272
UNKL unkempt family zinc finger-like 2.85541
DMBT1 deleted in malignant brain tumors 1 2.58554
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 2.58535
LAMA3 laminin, alpha 3 2.56075
SLC25A27 solute carrier family 25, member 27 2.47842
COL5A2 collagen, type V, alpha 2 2.47741
DUXA double homeobox A 2.45783
LRP12 low density lipoprotein receptor-related protein 12 2.42553
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.40766
GSG2 germ cell associated 2 (haspin) 2.33805
BCORL1 BCL6 corepressor-like 1 2.27968
RSPRY1 ring finger and SPRY domain containing 1 2.26736
NT5C2 5'-nucleotidase, cytosolic II 2.26596
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 2.20873
HMGN1 high mobility group nucleosome binding domain 1 2.17727
FOXI1 forkhead box I1 2.17099
ILF2 interleukin enhancer binding factor 2 2.15162
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 2.14514
OR6B3 olfactory receptor, family 6, subfamily B, member 3 2.14412
ZNF57 zinc finger protein 57 2.14269
KLK1 kallikrein 1 2.12692
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 2.1253
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 2.12272
AGTR1 angiotensin II receptor, type 1 2.11767
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.11675
TMPRSS13 transmembrane protease, serine 13 2.07252
ALG12 ALG12, alpha-1,6-mannosyltransferase 2.05978
GUCA1A guanylate cyclase activator 1A (retina) 2.04789
RPGR retinitis pigmentosa GTPase regulator 2.04486
MARCO macrophage receptor with collagenous structure 2.01921
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 1.97209
NSF N-ethylmaleimide-sensitive factor 1.96952
PEX5 peroxisomal biogenesis factor 5 1.96654
PARP8 poly (ADP-ribose) polymerase family, member 8 1.95879
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.95429
MCM6 minichromosome maintenance complex component 6 1.94964
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 1.9106
AJAP1 adherens junctions associated protein 1 1.88642
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 1.8824
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.87793
NELL1 NEL-like 1 (chicken) 1.86875
DCLK3 doublecortin-like kinase 3 1.84602
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 1.84459
TSC22D4 TSC22 domain family, member 4 1.8361
S100A4 S100 calcium binding protein A4 1.82792
BRD1 bromodomain containing 1 1.77464
FOXA3 forkhead box A3 1.76421
UBE2A ubiquitin-conjugating enzyme E2A 1.76053
SHBG sex hormone-binding globulin 1.74076
EFNB2 ephrin-B2 1.71891
RPA3 replication protein A3, 14kDa 1.71697
ODC1 ornithine decarboxylase 1 1.71054
TNPO3 transportin 3 1.69603
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.69267
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 1.68909
GLUD1 glutamate dehydrogenase 1 1.68237
ADORA3 adenosine A3 receptor 1.68192
AOC2 amine oxidase, copper containing 2 (retina-specific) 1.67949
COL11A1 collagen, type XI, alpha 1 1.66674
MOGAT1 monoacylglycerol O-acyltransferase 1 1.66462
SIN3B SIN3 transcription regulator family member B 1.66127
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 1.66097
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 1.65344
POLB polymerase (DNA directed), beta 1.64932
ADGRF1 adhesion G protein-coupled receptor F1 1.64678
IGF2R insulin-like growth factor 2 receptor 1.63151
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 1.62211
ARHGAP35 Rho GTPase activating protein 35 1.62001
TRPS1 trichorhinophalangeal syndrome I 1.61413
NANP N-acetylneuraminic acid phosphatase 1.59806
LRMP lymphoid-restricted membrane protein 1.58582
TSC2 tuberous sclerosis 2 1.57862
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 1.57596
OXCT1 3-oxoacid CoA transferase 1 1.57033
INTS6 integrator complex subunit 6 1.54824
ZNF16 zinc finger protein 16 1.53424
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 1.53172
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 1.52988
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 1.52093
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 1.51911
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.51576
ZNF254 zinc finger protein 254 1.50834
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 1.50068
DPP6 dipeptidyl-peptidase 6 1.49309
EIF4A1 eukaryotic translation initiation factor 4A1 1.47941
ARL13B ADP-ribosylation factor-like 13B 1.4792
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 1.47671
AP2M1 adaptor-related protein complex 2, mu 1 subunit 1.47377
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 1.47097
KIF20A kinesin family member 20A 1.46964
GPR22 G protein-coupled receptor 22 1.45862
SENP3-EIF4A1 SENP3-EIF4A1 readthrough (NMD candidate) 1.45627
KLHL9 kelch-like family member 9 1.44429
FUBP3 far upstream element (FUSE) binding protein 3 1.42758
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 1.42725
FGD5 FYVE, RhoGEF and PH domain containing 5 1.42051
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 1.41245
TPTE transmembrane phosphatase with tensin homology 1.41137
FLNB filamin B, beta 1.41066
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.40399
ELF5 E74-like factor 5 (ets domain transcription factor) 1.39575
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 1.38801
PREPL prolyl endopeptidase-like 1.38089
STON1 stonin 1 1.37759
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.37078
STAT5B signal transducer and activator of transcription 5B 1.36861
EFCAB3 EF-hand calcium binding domain 3 1.3669
ERBB2 erb-b2 receptor tyrosine kinase 2 1.36664
WSB2 WD repeat and SOCS box containing 2 1.36123
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 1.3515
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 1.34565
DCTN1 dynactin 1 1.33822
MED13L mediator complex subunit 13-like 1.33813
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 1.33555
ZRANB2 zinc finger, RAN-binding domain containing 2 1.33398
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 1.33309
CABLES1 Cdk5 and Abl enzyme substrate 1 1.31796
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.31219
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 1.31156
GMPR guanosine monophosphate reductase 1.31144
PZP pregnancy-zone protein 1.30655
FLT3 fms-related tyrosine kinase 3 1.29541
ELF1 E74-like factor 1 (ets domain transcription factor) 1.29259
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 1.28752
RPS17 ribosomal protein S17 1.28632
TRIB3 tribbles pseudokinase 3 1.2825
HCAR2 hydroxycarboxylic acid receptor 2 1.2807
BRD8 bromodomain containing 8 1.28
PTGR1 prostaglandin reductase 1 1.27986
CLK2P1 CDC-like kinase 2, pseudogene 1 1.27299
TRIP11 thyroid hormone receptor interactor 11 1.27172
SMC2 structural maintenance of chromosomes 2 1.24374
UBB ubiquitin B 1.24328
SLCO1B1 solute carrier organic anion transporter family, member 1B1 1.23794
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1.23713
PRSS35 protease, serine, 35 1.23654
SIX4 SIX homeobox 4 1.23095
MTA1 metastasis associated 1 1.22215
TGFB2 transforming growth factor, beta 2 1.21505
PAX4 paired box 4 1.21422
PEX1 peroxisomal biogenesis factor 1 1.21014
RNF167 ring finger protein 167 1.1988
SLC17A4 solute carrier family 17, member 4 1.18905
PRDM5 PR domain containing 5 1.18111
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12 1.18095
PRKY protein kinase, Y-linked, pseudogene 1.17571
PABPN1 poly(A) binding protein, nuclear 1 1.17439
KLRB1 killer cell lectin-like receptor subfamily B, member 1 1.16958
UBE3B ubiquitin protein ligase E3B 1.16898
SLC39A10 solute carrier family 39 (zinc transporter), member 10 1.16737
ZWILCH zwilch kinetochore protein 1.1606
MGP matrix Gla protein 1.15952
ATP13A2 ATPase type 13A2 1.15831
SLIT2 slit homolog 2 (Drosophila) 1.15675
HLA-C major histocompatibility complex, class I, C 1.15564
OR8G5 olfactory receptor, family 8, subfamily G, member 5 1.15564
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 1.15254
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 1.14442
ACSL6 acyl-CoA synthetase long-chain family member 6 1.14193
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.14002
DARS aspartyl-tRNA synthetase 1.13623
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.13607
MYEF2 myelin expression factor 2 1.1356
CDK9 cyclin-dependent kinase 9 1.13503
CAPSL calcyphosine-like 1.12896
CASP8AP2 caspase 8 associated protein 2 1.11945
FASN fatty acid synthase 1.11346
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.11341
PTER phosphotriesterase related 1.10903
OR2T1 olfactory receptor, family 2, subfamily T, member 1 1.10753
ZNF835 zinc finger protein 835 1.10595
ABLIM3 actin binding LIM protein family, member 3 1.10585
SRSF1 serine/arginine-rich splicing factor 1 1.10215
DGKG diacylglycerol kinase, gamma 90kDa 1.10063
TCEA1 transcription elongation factor A (SII), 1 1.09692
RHOT1 ras homolog family member T1 1.09238
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 1.08928
RBP5 retinol binding protein 5, cellular 1.08531
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.08125
LOC652119 1.08098
MUC7 mucin 7, secreted 1.07941
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 1.07437
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 1.06909
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.06626
CLDN3 claudin 3 1.06343
NUP160 nucleoporin 160kDa 1.06322
CPB2 carboxypeptidase B2 (plasma) 1.06127
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 1.06079
ITGA7 integrin, alpha 7 1.06004
CCDC146 coiled-coil domain containing 146 1.05432
MDH1 malate dehydrogenase 1, NAD (soluble) 1.05122
GPR160 G protein-coupled receptor 160 1.0496
RPL7 ribosomal protein L7 1.04704
FBXO3 F-box protein 3 1.04599
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 1.04291
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 1.03805
FETUB fetuin B 1.03802
CNOT7 CCR4-NOT transcription complex, subunit 7 1.03181
LDHA lactate dehydrogenase A 1.02681
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 1.02103
DRD3 dopamine receptor D3 1.01939
PLCZ1 phospholipase C, zeta 1 1.01308
EIF3E eukaryotic translation initiation factor 3, subunit E 1.0124
GPR83 G protein-coupled receptor 83 1.01041
URM1 ubiquitin related modifier 1 1.00857
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 1.00469
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 1.00393
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2 1.00349

decreased fitness

Symbol Name Standardized Value
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -3.27355
TMPRSS11B transmembrane protease, serine 11B -3.26232
MOS v-mos Moloney murine sarcoma viral oncogene homolog -2.92111
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -2.67319
GALK2 galactokinase 2 -2.326
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled -2.3025
SLC39A5 solute carrier family 39 (zinc transporter), member 5 -2.29331
CARD14 caspase recruitment domain family, member 14 -2.24675
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -2.24271
C4BPB complement component 4 binding protein, beta -2.19841
PCSK6 proprotein convertase subtilisin/kexin type 6 -2.16904
E2F1 E2F transcription factor 1 -2.09244
CHID1 chitinase domain containing 1 -2.06333
WFDC12 WAP four-disulfide core domain 12 -2.0461
HBE1 hemoglobin, epsilon 1 -2.0321
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 -1.99422
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -1.96676
ZFP36L2 ZFP36 ring finger protein-like 2 -1.95718
CSAD cysteine sulfinic acid decarboxylase -1.93783
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 -1.91758
PAPD7 PAP associated domain containing 7 -1.91553
CLDN14 claudin 14 -1.88772
SLC17A2 solute carrier family 17, member 2 -1.88477
TIGD6 tigger transposable element derived 6 -1.86739
MAPK4 mitogen-activated protein kinase 4 -1.83325
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase -1.82963
CAMKV CaM kinase-like vesicle-associated -1.82197
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 -1.82053
GSC goosecoid homeobox -1.79746
OR52B2 olfactory receptor, family 52, subfamily B, member 2 -1.78503
DGKQ diacylglycerol kinase, theta 110kDa -1.76359
CBR3 carbonyl reductase 3 -1.73366
RGN regucalcin -1.71705
GALR2 galanin receptor 2 -1.71502
SNX15 sorting nexin 15 -1.69684
H2AFB2 H2A histone family, member B2 -1.69332
RAB36 RAB36, member RAS oncogene family -1.67094
RXRB retinoid X receptor, beta -1.66444
RFX1 regulatory factor X, 1 (influences HLA class II expression) -1.66401
ZNF160 zinc finger protein 160 -1.63006
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -1.62488
ZFX zinc finger protein, X-linked -1.62281
MBOAT7 membrane bound O-acyltransferase domain containing 7 -1.61177
PCYOX1 prenylcysteine oxidase 1 -1.60873
SASH3 SAM and SH3 domain containing 3 -1.60344
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta -1.59691
OR2J2 olfactory receptor, family 2, subfamily J, member 2 -1.59157
GUCY2F guanylate cyclase 2F, retinal -1.59154
PEBP4 phosphatidylethanolamine-binding protein 4 -1.58408
NUB1 negative regulator of ubiquitin-like proteins 1 -1.57791
INS-IGF2 INS-IGF2 readthrough -1.57543
CHEK2 checkpoint kinase 2 -1.57263
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -1.56505
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -1.56391
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -1.54212
THOP1 thimet oligopeptidase 1 -1.52283
HES6 hes family bHLH transcription factor 6 -1.5145
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -1.50978
WWOX WW domain containing oxidoreductase -1.48555
GIF gastric intrinsic factor (vitamin B synthesis) -1.48037
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -1.47363
NEK11 NIMA-related kinase 11 -1.46361
CSF3 colony stimulating factor 3 (granulocyte) -1.46349
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -1.4587
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 -1.44669
PHACTR3 phosphatase and actin regulator 3 -1.44448
ZNF146 zinc finger protein 146 -1.44331
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -1.443
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -1.4399
FGF17 fibroblast growth factor 17 -1.43405
KRT73 keratin 73, type II -1.42559
HIPK4 homeodomain interacting protein kinase 4 -1.42315
PSKH1 protein serine kinase H1 -1.41581
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -1.41526
DPEP2 dipeptidase 2 -1.41214
PPA1 pyrophosphatase (inorganic) 1 -1.40661
RGS19 regulator of G-protein signaling 19 -1.40634
CKM creatine kinase, muscle -1.40486
HIST1H3G histone cluster 1, H3g -1.39808
SOX4 SRY (sex determining region Y)-box 4 -1.39797
EFNA3 ephrin-A3 -1.39517
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -1.379
IL9R interleukin 9 receptor -1.37657
ASGR1 asialoglycoprotein receptor 1 -1.36858
AQP12A aquaporin 12A -1.35184
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 -1.35126
SYT7 synaptotagmin VII -1.34976
MNX1 motor neuron and pancreas homeobox 1 -1.34919
KHSRP KH-type splicing regulatory protein -1.34589
SOCS6 suppressor of cytokine signaling 6 -1.34379
LPPR3 lipid phosphate phosphatase-related protein type 3 -1.33793
FYN FYN proto-oncogene, Src family tyrosine kinase -1.3366
UCK2 uridine-cytidine kinase 2 -1.33322
SHOX2 short stature homeobox 2 -1.32845
ASRGL1 asparaginase like 1 -1.32386
PLK4 polo-like kinase 4 -1.32217
CABP4 calcium binding protein 4 -1.31834
PRKACG protein kinase, cAMP-dependent, catalytic, gamma -1.31803
SOAT2 sterol O-acyltransferase 2 -1.31702
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa -1.31551
DYNLT3 dynein, light chain, Tctex-type 3 -1.30511
ULBP3 UL16 binding protein 3 -1.29639
BBS1 Bardet-Biedl syndrome 1 -1.29482
LRRK2 leucine-rich repeat kinase 2 -1.29115
CD96 CD96 molecule -1.28991
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -1.28584
FGFR3 fibroblast growth factor receptor 3 -1.27709
NLK nemo-like kinase -1.26852
ACOT2 acyl-CoA thioesterase 2 -1.26751
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -1.26702
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -1.26434
LZIC leucine zipper and CTNNBIP1 domain containing -1.26302
MMP14 matrix metallopeptidase 14 (membrane-inserted) -1.2496
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -1.24601
NUMBL numb homolog (Drosophila)-like -1.23888
NPC2 Niemann-Pick disease, type C2 -1.2287
KRT8 keratin 8, type II -1.22141
DMBX1 diencephalon/mesencephalon homeobox 1 -1.2212
CCDC71 coiled-coil domain containing 71 -1.21397
GLUL glutamate-ammonia ligase -1.2125
TCL1A T-cell leukemia/lymphoma 1A -1.20498
LOC256374 peptidylprolyl isomerase A (cyclophilin A) pseudogene -1.19467
WNT9B wingless-type MMTV integration site family, member 9B -1.19357
MAPKBP1 mitogen-activated protein kinase binding protein 1 -1.19042
ASMTL acetylserotonin O-methyltransferase-like -1.1733
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -1.17279
KCNG4 potassium channel, voltage gated modifier subfamily G, member 4 -1.17203
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) -1.1708
CIB3 calcium and integrin binding family member 3 -1.1632
FXYD7 FXYD domain containing ion transport regulator 7 -1.15989
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -1.15519
C1RL complement component 1, r subcomponent-like -1.14637
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -1.13751
TWIST2 twist family bHLH transcription factor 2 -1.13418
PHKG2 phosphorylase kinase, gamma 2 (testis) -1.12935
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -1.12507
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M -1.12181
TCF19 transcription factor 19 -1.12029
COBL cordon-bleu WH2 repeat protein -1.11186
CCNL1 cyclin L1 -1.11103
PRSS33 protease, serine, 33 -1.10997
DPYD dihydropyrimidine dehydrogenase -1.10967
DRG2 developmentally regulated GTP binding protein 2 -1.10852
WFDC5 WAP four-disulfide core domain 5 -1.10045
GJA3 gap junction protein, alpha 3, 46kDa -1.09912
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 -1.09812
GPR119 G protein-coupled receptor 119 -1.09554
TRRAP transformation/transcription domain-associated protein -1.09528
CCR10 chemokine (C-C motif) receptor 10 -1.09373
SAMD4B sterile alpha motif domain containing 4B -1.09317
CTSG cathepsin G -1.0911
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -1.08263
SLC14A2 solute carrier family 14 (urea transporter), member 2 -1.07658
MPO myeloperoxidase -1.06837
CCNI cyclin I -1.06829
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -1.06803
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -1.06662
DUSP18 dual specificity phosphatase 18 -1.06632
RGS16 regulator of G-protein signaling 16 -1.06561
DPP3 dipeptidyl-peptidase 3 -1.06457
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.05996
SYT4 synaptotagmin IV -1.05934
GRM8 glutamate receptor, metabotropic 8 -1.05819
KLF6 Kruppel-like factor 6 -1.05546
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -1.05415
EFCAB11 EF-hand calcium binding domain 11 -1.05207
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) -1.04735
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -1.04486
PCDHGB3 protocadherin gamma subfamily B, 3 -1.04457
UBE2J2 ubiquitin-conjugating enzyme E2, J2 -1.03644
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -1.03522
SNRPA small nuclear ribonucleoprotein polypeptide A -1.03039
AGTRAP angiotensin II receptor-associated protein -1.02967
SFXN1 sideroflexin 1 -1.02915
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -1.02519
H3F3C H3 histone, family 3C -1.02417
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -1.02415
SENP5 SUMO1/sentrin specific peptidase 5 -1.0241
CALML3 calmodulin-like 3 -1.0204
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -1.01995
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 -1.01502
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -1.01365
FER fer (fps/fes related) tyrosine kinase -1.01326
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -1.01146
SF3A3 splicing factor 3a, subunit 3, 60kDa -1.00907
SLC18B1 solute carrier family 18, subfamily B, member 1 -1.00804
REXO2 RNA exonuclease 2 -1.00659
TSHZ2 teashirt zinc finger homeobox 2 -1.00552
UBL4A ubiquitin-like 4A -1.0043
AFG3L1P AFG3-like AAA ATPase 1, pseudogene -1.00383
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial -1.00277
BRCA1 breast cancer 1, early onset -1.00158
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 -1.00141