TTI1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description TELO2 interacting protein 1| (NCBI Entrez Gene Database, 9675)
External Link https://ncbi.nlm.nih.gov/gene/9675
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Genes

498 genes differentially expressed following the TTI1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 0.0177089
TFPI2 tissue factor pathway inhibitor 2 0.0150065
SCGB2A1 secretoglobin, family 2A, member 1 0.0148602
GNAS GNAS complex locus 0.0146749
NOTCH2NL notch 2 N-terminal like 0.0144868
SCGB2A2 secretoglobin, family 2A, member 2 0.0136354
KLF6 Kruppel-like factor 6 0.0132027
HSPB8 heat shock 22kDa protein 8 0.0130966
SRPX sushi-repeat containing protein, X-linked 0.0129283
PLAAT3 phospholipase A and acyltransferase 3 0.0122577
MSX1 msh homeobox 1 0.0122378
TFF3 trefoil factor 3 (intestinal) 0.0119156
MX1 MX dynamin-like GTPase 1 0.011749
GOLGA8A golgin A8 family, member A 0.0115709
GOLGA8H golgin A8 family, member H 0.0115083
STK10 serine/threonine kinase 10 0.0114682
PUF60 poly-U binding splicing factor 60KDa 0.0113077
IGF1 insulin-like growth factor 1 (somatomedin C) 0.0112804
ANO1 anoctamin 1, calcium activated chloride channel 0.0108402
GREB1 growth regulation by estrogen in breast cancer 1 0.0107976
GPM6B glycoprotein M6B 0.0107545
OGN osteoglycin 0.0107135
PCSK5 proprotein convertase subtilisin/kexin type 5 0.0106541
COL14A1 collagen, type XIV, alpha 1 0.0105886
MATN2 matrilin 2 0.010576
PDGFRL platelet-derived growth factor receptor-like 0.0104691
ANKRD10 ankyrin repeat domain 10 0.010408
CLEC11A C-type lectin domain family 11, member A 0.010306
ESR1 estrogen receptor 1 0.0102221
VCAN versican 0.0101977
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0101854
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0101739
SCGB1D2 secretoglobin, family 1D, member 2 0.0100426
THBS4 thrombospondin 4 0.0100413
CES1 carboxylesterase 1 0.0100228
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0100186
NFIB nuclear factor I/B 0.00995027
XIC X chromosome inactivation center 0.00989448
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00975726
TPBG trophoblast glycoprotein 0.00974494
TTC39A tetratricopeptide repeat domain 39A 0.0096565
MPDZ multiple PDZ domain protein 0.009644
MAGEA12 melanoma antigen family A12 0.00961034
JMJD1C jumonji domain containing 1C 0.00955818
TM9SF3 transmembrane 9 superfamily member 3 0.00954117
PLAT plasminogen activator, tissue 0.00952919
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00950166
PROM1 prominin 1 0.00946215
S100A11 S100 calcium binding protein A11 0.00936831
CRIP1 cysteine-rich protein 1 (intestinal) 0.00936744
OXTR oxytocin receptor 0.0093463
MLPH melanophilin 0.00934176
DEFB1 defensin, beta 1 0.00928356
SGPL1 sphingosine-1-phosphate lyase 1 0.00928216
MGLL monoglyceride lipase 0.0092738
FHL1 four and a half LIM domains 1 0.00926274
LAMP5 lysosomal-associated membrane protein family, member 5 0.00920169
NID1 nidogen 1 0.00918244
HEATR1 HEAT repeat containing 1 0.00916518
TJP2 tight junction protein 2 0.00914196
TACSTD2 tumor-associated calcium signal transducer 2 0.00914176
APOD apolipoprotein D 0.00913469
LAMA2 laminin, alpha 2 0.00907701
ASRGL1 asparaginase like 1 0.00899691
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00899114
TUBA1A tubulin, alpha 1a 0.00875162
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00868902
TAC1 tachykinin, precursor 1 0.00864657
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00863558
AGR2 anterior gradient 2 0.00862116
COL4A5 collagen, type IV, alpha 5 0.00857933
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00856308
DPT dermatopontin 0.00850757
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00849941
SNX1 sorting nexin 1 0.00848311
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0084192
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00841576
COX6C cytochrome c oxidase subunit VIc 0.00840295
PTN pleiotrophin 0.00837412
COL15A1 collagen, type XV, alpha 1 0.00835964
FAM189A2 family with sequence similarity 189, member A2 0.00833562
S100A10 S100 calcium binding protein A10 0.00831999
MAGEA3 melanoma antigen family A3 0.00829053
SYNM synemin, intermediate filament protein 0.00828533
BCHE butyrylcholinesterase 0.00819668
LONP2 lon peptidase 2, peroxisomal 0.00818895
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00817806
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00814242
CALCA calcitonin-related polypeptide alpha 0.0081205
MFAP5 microfibrillar associated protein 5 0.00810297
LMCD1 LIM and cysteine-rich domains 1 0.00806884
PNN pinin, desmosome associated protein 0.0080593
SASH1 SAM and SH3 domain containing 1 0.00801172
MXRA5 matrix-remodelling associated 5 0.00801146
OSR2 odd-skipped related transciption factor 2 0.00798
MYOF myoferlin 0.00796881
SFRP1 secreted frizzled-related protein 1 0.00796414
SCRIB scribbled planar cell polarity protein 0.00796169
TGFBR3 transforming growth factor, beta receptor III 0.00795773
SMC1A structural maintenance of chromosomes 1A 0.00795523
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00794976
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00793296
RBPMS RNA binding protein with multiple splicing 0.0079325
IGF1R insulin-like growth factor 1 receptor 0.00792837
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.00788996
PDZK1 PDZ domain containing 1 0.00788297
NBPF10 neuroblastoma breakpoint family, member 10 0.00787892
RSRP1 arginine/serine-rich protein 1 0.00787334
KLHL41 kelch-like family member 41 0.00787084
MBD1 methyl-CpG binding domain protein 1 0.00786436
RBM26 RNA binding motif protein 26 0.00785673
SPON2 spondin 2, extracellular matrix protein 0.00784846
GLA galactosidase, alpha 0.00783955
CD93 CD93 molecule 0.00783835
PTHLH parathyroid hormone-like hormone 0.00779359
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00778858
MCL1 myeloid cell leukemia 1 0.00778714
FRY furry homolog (Drosophila) 0.00774013
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.00770523
LAMB1 laminin, beta 1 0.00770479
ZBTB10 zinc finger and BTB domain containing 10 0.00769514
GAB2 GRB2-associated binding protein 2 0.00768822
REEP1 receptor accessory protein 1 0.00768267
TPPP3 tubulin polymerization-promoting protein family member 3 0.00762053
LGALS1 lectin, galactoside-binding, soluble, 1 0.0076137
AHNAK AHNAK nucleoprotein 0.00756987
ZNF516 zinc finger protein 516 0.00749525
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00749247
RET ret proto-oncogene 0.00747401
PBX3 pre-B-cell leukemia homeobox 3 0.00745864
SOX17 SRY (sex determining region Y)-box 17 0.00743595
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00736406
SAMD4A sterile alpha motif domain containing 4A 0.00736226
RGS5 regulator of G-protein signaling 5 0.00735669
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00735075
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00734146
CSAD cysteine sulfinic acid decarboxylase 0.00733713
TFF1 trefoil factor 1 0.00732621
NCALD neurocalcin delta 0.00732329
DMD dystrophin 0.00732122
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00729881
RBM25 RNA binding motif protein 25 0.00728322
SLIT2 slit homolog 2 (Drosophila) 0.00727918
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00726479
CCNA2 cyclin A2 0.0072566
TIMP1 TIMP metallopeptidase inhibitor 1 0.0072233
SORBS1 sorbin and SH3 domain containing 1 0.00722237
NID2 nidogen 2 (osteonidogen) 0.00720616
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00718401
NLGN4X neuroligin 4, X-linked 0.00717444
PLAGL1 pleiomorphic adenoma gene-like 1 0.00716704
EDNRB endothelin receptor type B 0.00712698
SCG5 secretogranin V 0.00710996
PTEN phosphatase and tensin homolog 0.00709612
TMEM255A transmembrane protein 255A 0.00707388
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.00707378
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00706433
PGR progesterone receptor 0.00705821
ASPN asporin 0.00705101
ZBTB20 zinc finger and BTB domain containing 20 0.00703579
CELF2 CUGBP, Elav-like family member 2 0.00702851
AKAP12 A kinase (PRKA) anchor protein 12 0.00701472
COL16A1 collagen, type XVI, alpha 1 0.00700156
ACAD8 acyl-CoA dehydrogenase family, member 8 0.00699618
IL6R interleukin 6 receptor 0.00698665
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.00698479
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00696768
HOXC6 homeobox C6 0.0069526
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.00694669
CRYAB crystallin, alpha B 0.0069429
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00693959
BCL6 B-cell CLL/lymphoma 6 0.00693373
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00691648
ANXA5 annexin A5 0.00691488
ISG15 ISG15 ubiquitin-like modifier 0.00691213
ARGLU1 arginine and glutamate rich 1 0.00689954
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.00688976
ARHGAP29 Rho GTPase activating protein 29 0.00688428
PANX1 pannexin 1 0.00686233
GRB14 growth factor receptor-bound protein 14 0.00685788
ADGRA2 adhesion G protein-coupled receptor A2 0.00685595
MITF microphthalmia-associated transcription factor 0.00684048
PLCE1 phospholipase C, epsilon 1 0.00682244
STON1 stonin 1 0.00680937
VLDLR very low density lipoprotein receptor 0.00679356
SOX4 SRY (sex determining region Y)-box 4 0.00677586
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.00676937
WBP4 WW domain binding protein 4 0.0067691
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00675813
SCAF4 SR-related CTD-associated factor 4 0.00674847
CHD4 chromodomain helicase DNA binding protein 4 0.00674775
HSPA1A heat shock 70kDa protein 1A 0.00674523
MCAM melanoma cell adhesion molecule 0.00674055
CAPN6 calpain 6 0.00673804
EPCAM epithelial cell adhesion molecule 0.00672584
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00671795
MT1E metallothionein 1E 0.00667783
EGR3 early growth response 3 0.0066648
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.0066618
PEG10 paternally expressed 10 0.00665346
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.00664885
PNISR PNN-interacting serine/arginine-rich protein 0.00664419
SOBP sine oculis binding protein homolog (Drosophila) 0.00663927
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.00663081
TMPRSS4 transmembrane protease, serine 4 0.00662175
CD36 CD36 molecule (thrombospondin receptor) 0.0066195
CTSC cathepsin C 0.00661948
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.00661368
HMBOX1 homeobox containing 1 0.00661322
PDLIM5 PDZ and LIM domain 5 0.00660701
CPD carboxypeptidase D 0.00660531
SACS sacsin molecular chaperone 0.00659706
FGL1 fibrinogen-like 1 0.00659444
MYBPC1 myosin binding protein C, slow type 0.00657491
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00656619
RUFY2 RUN and FYVE domain containing 2 0.00653868
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.00652403
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00651094
KLC1 kinesin light chain 1 0.00649493
RASA4 RAS p21 protein activator 4 0.00649033
ZNF721 zinc finger protein 721 0.00648922
RRBP1 ribosome binding protein 1 0.00648461
ANKRD11 ankyrin repeat domain 11 0.0064497
TMEM176B transmembrane protein 176B 0.00643318
MAGEA1 melanoma antigen family A1 0.00643166
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.00642182
PRNP prion protein 0.00641414
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00641028
NES nestin 0.00640795
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00640132
MAGED1 melanoma antigen family D1 0.00639633
CPT1A carnitine palmitoyltransferase 1A (liver) 0.00639116
FGB fibrinogen beta chain 0.00634766
RUFY3 RUN and FYVE domain containing 3 0.00633759
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.00632587
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00631951
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.0063048
LAMA3 laminin, alpha 3 0.00629387
COBL cordon-bleu WH2 repeat protein 0.00629366
ARID4B AT rich interactive domain 4B (RBP1-like) 0.00628488
FLT3 fms-related tyrosine kinase 3 0.00628281
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00627734
MYO5C myosin VC 0.00627546
WWTR1 WW domain containing transcription regulator 1 0.00627154
HAUS2 HAUS augmin-like complex, subunit 2 0.00625476
TUBB6 tubulin, beta 6 class V 0.00624775
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.00624108
LIPG lipase, endothelial 0.00623072
KLF10 Kruppel-like factor 10 0.00620776

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -0.020899
S100A9 S100 calcium binding protein A9 -0.0203909
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0152567
LTF lactotransferrin -0.012704
HBD hemoglobin, delta -0.012021
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0119319
MMP9 matrix metallopeptidase 9 -0.0115294
TGFB1 transforming growth factor, beta 1 -0.0114642
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0110913
CD52 CD52 molecule -0.0109437
MMP12 matrix metallopeptidase 12 -0.0107757
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0106943
H1-2 H1.2 linker histone, cluster member -0.0106263
CCDC85B coiled-coil domain containing 85B -0.0106076
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.010299
DEFA4 defensin, alpha 4, corticostatin -0.0100943
EVI2A ecotropic viral integration site 2A -0.00998587
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -0.00992469
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00982808
TPSAB1 tryptase alpha/beta 1 -0.00981717
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00969439
TPM4 tropomyosin 4 -0.00968227
ADM adrenomedullin -0.00967533
CA2 carbonic anhydrase II -0.009624
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00960967
TMEM14B transmembrane protein 14B -0.00960547
ETHE1 ethylmalonic encephalopathy 1 -0.00960051
FGFR3 fibroblast growth factor receptor 3 -0.00954999
CEMIP cell migration inducing protein, hyaluronan binding -0.00947353
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00923722
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00921192
LOX lysyl oxidase -0.00917671
VSNL1 visinin-like 1 -0.00916992
PLBD1 phospholipase B domain containing 1 -0.00916129
CST7 cystatin F (leukocystatin) -0.00914212
BPI bactericidal/permeability-increasing protein -0.00909429
PI3 peptidase inhibitor 3, skin-derived -0.0090567
MALL mal, T-cell differentiation protein-like -0.00894139
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.0088507
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00880705
CCNB2 cyclin B2 -0.00877714
CAMP cathelicidin antimicrobial peptide -0.00876964
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00876102
GRB7 growth factor receptor-bound protein 7 -0.0087582
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00855537
GSTO1 glutathione S-transferase omega 1 -0.00855035
CLC Charcot-Leyden crystal galectin -0.00844087
AQP3 aquaporin 3 (Gill blood group) -0.00842046
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00833039
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.0083267
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00830451
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00828956
LYPD3 LY6/PLAUR domain containing 3 -0.00823529
PKM pyruvate kinase, muscle -0.00823099
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00817122
MAT2B methionine adenosyltransferase II, beta -0.0079973
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00793458
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00793055
KDM5D lysine (K)-specific demethylase 5D -0.00791624
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.00790862
P3H2 prolyl 3-hydroxylase 2 -0.00782777
GJA1 gap junction protein, alpha 1, 43kDa -0.00779464
VPREB3 pre-B lymphocyte 3 -0.00777236
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00774093
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00773206
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0077252
IFRD2 interferon-related developmental regulator 2 -0.00770072
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00765116
LCN2 lipocalin 2 -0.00764896
CLCN3 chloride channel, voltage-sensitive 3 -0.00762224
FSCN1 fascin actin-bundling protein 1 -0.00761307
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00758625
CD2 CD2 molecule -0.00758238
ZNF395 zinc finger protein 395 -0.00747081
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00746012
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00741503
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -0.00741147
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00738916
SDC1 syndecan 1 -0.00738208
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00736049
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00732263
NDRG1 N-myc downstream regulated 1 -0.00731694
KRT16 keratin 16, type I -0.00729368
PDZK1IP1 PDZK1 interacting protein 1 -0.00723424
RSL1D1 ribosomal L1 domain containing 1 -0.00721525
ELANE elastase, neutrophil expressed -0.0072044
CRISP3 cysteine-rich secretory protein 3 -0.00716062
FPR1 formyl peptide receptor 1 -0.00715698
LST1 leukocyte specific transcript 1 -0.00707968
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -0.00707547
LYRM4 LYR motif containing 4 -0.00707525
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.00707471
CRYM crystallin, mu -0.00704932
CRLF1 cytokine receptor-like factor 1 -0.0070449
TRIB2 tribbles pseudokinase 2 -0.0070334
PTPRF protein tyrosine phosphatase, receptor type, F -0.00696746
S100A12 S100 calcium binding protein A12 -0.00695307
IPO13 importin 13 -0.00694578
CSTA cystatin A (stefin A) -0.00694484
TAL1 T-cell acute lymphocytic leukemia 1 -0.00689083
IL7R interleukin 7 receptor -0.00686381
S100P S100 calcium binding protein P -0.00682809
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -0.00681025
SSBP3 single stranded DNA binding protein 3 -0.00679049
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0067567
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00674611
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) -0.00674607
CREBL2 cAMP responsive element binding protein-like 2 -0.00669235
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00665681
PTPRO protein tyrosine phosphatase, receptor type, O -0.00663062
CD9 CD9 molecule -0.00661233
VCAM1 vascular cell adhesion molecule 1 -0.00654635
DUOX2 dual oxidase 2 -0.00654027
IDO1 indoleamine 2,3-dioxygenase 1 -0.00653248
ADAMDEC1 ADAM-like, decysin 1 -0.00652266
C7ORF49 chromosome 7 open reading frame 49 -0.00647379
SOCS1 suppressor of cytokine signaling 1 -0.0064715
ACOX2 acyl-CoA oxidase 2, branched chain -0.00643947
ZDHHC6 zinc finger, DHHC-type containing 6 -0.0064013
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -0.00637217
CYB5A cytochrome b5 type A (microsomal) -0.0063718
COCH cochlin -0.00637121
AIM2 absent in melanoma 2 -0.00635015
DHCR24 24-dehydrocholesterol reductase -0.00634917
BCL2A1 BCL2-related protein A1 -0.0063439
GTPBP1 GTP binding protein 1 -0.00634258
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00634225
ZMYM3 zinc finger, MYM-type 3 -0.00633617
STAC SH3 and cysteine rich domain -0.00632523
MGAM maltase-glucoamylase -0.00631353
AHSP alpha hemoglobin stabilizing protein -0.00628409
NELL2 NEL-like 2 (chicken) -0.00627643
MEA1 male-enhanced antigen 1 -0.00627446
CIAO3 cytosolic iron-sulfur assembly component 3 -0.006266
TSPAN8 tetraspanin 8 -0.00626491
CHN1 chimerin 1 -0.00624891
CNPY3 canopy FGF signaling regulator 3 -0.00624843
TTLL12 tubulin tyrosine ligase-like family member 12 -0.00624724
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0062345
LTB lymphotoxin beta (TNF superfamily, member 3) -0.00622094
FAM162A family with sequence similarity 162, member A -0.00621995
FXYD2 FXYD domain containing ion transport regulator 2 -0.00621324
RPS5 ribosomal protein S5 -0.00621122
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00620798
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -0.0061951
MRPS18A mitochondrial ribosomal protein S18A -0.0061809
MSMO1 methylsterol monooxygenase 1 -0.006152
HLA-DOB major histocompatibility complex, class II, DO beta -0.00613848
CNN3 calponin 3, acidic -0.00612798
RNASE6 ribonuclease, RNase A family, k6 -0.00611253
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0061046
COMMD3 COMM domain containing 3 -0.00610177
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00610057
ADORA2B adenosine A2b receptor -0.00609812
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00609463
RBX1 ring-box 1, E3 ubiquitin protein ligase -0.0060891
RUSF1 RUS family member 1 -0.00608882
TMPRSS2 transmembrane protease, serine 2 -0.00608067
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00607567
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -0.00607244
KLHDC3 kelch domain containing 3 -0.00606912
MRTFB myocardin related transcription factor B -0.00606146
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -0.00605527
TECR trans-2,3-enoyl-CoA reductase -0.00604332
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.0060254
NRGN neurogranin (protein kinase C substrate, RC3) -0.00599326
IL1RN interleukin 1 receptor antagonist -0.00597805
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00597107
IGSF6 immunoglobulin superfamily, member 6 -0.00596228
CD177 CD177 molecule -0.00595122
SIRT3 sirtuin 3 -0.0059271
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.00590774
DCK deoxycytidine kinase -0.00590638
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein -0.00589943
NARF nuclear prelamin A recognition factor -0.0058849
ITGA6 integrin, alpha 6 -0.00585401
RPL10A ribosomal protein L10a -0.00584837
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00583005
CUTA cutA divalent cation tolerance homolog (E. coli) -0.00582871
HK2 hexokinase 2 -0.00582513
BAMBI BMP and activin membrane-bound inhibitor -0.0058134
BLVRB biliverdin reductase B -0.00581236
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.00580206
KLF1 Kruppel-like factor 1 (erythroid) -0.00580153
HDDC2 HD domain containing 2 -0.00579829
HMBS hydroxymethylbilane synthase -0.00579723
CTSS cathepsin S -0.00579329
TUBA4A tubulin, alpha 4a -0.00578805
CPE carboxypeptidase E -0.00575734
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -0.00575692
CLEC10A C-type lectin domain family 10, member A -0.00575437
CLEC5A C-type lectin domain family 5, member A -0.00574612
HCRT hypocretin (orexin) neuropeptide precursor -0.00574091
BTN3A1 butyrophilin, subfamily 3, member A1 -0.0057357
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00572853
EPHA1 EPH receptor A1 -0.00572777
SPRR1B small proline-rich protein 1B -0.0057274
ZNF274 zinc finger protein 274 -0.00571344
FABP6 fatty acid binding protein 6, ileal -0.00571143
GCHFR GTP cyclohydrolase I feedback regulator -0.00570137
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00569914
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.005698
MRPL40 mitochondrial ribosomal protein L40 -0.00569714
CD79A CD79a molecule, immunoglobulin-associated alpha -0.0056805
CHPT1 choline phosphotransferase 1 -0.00567245
CCRL2 chemokine (C-C motif) receptor-like 2 -0.00565881
ZDHHC4 zinc finger, DHHC-type containing 4 -0.00565132
CD48 CD48 molecule -0.00563244
TM4SF1 transmembrane 4 L six family member 1 -0.00562623
PF4 platelet factor 4 -0.00562421
MAL mal, T-cell differentiation protein -0.00562262
MRPS16 mitochondrial ribosomal protein S16 -0.00561954
ATXN10 ataxin 10 -0.00561896
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.0056179
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00561684
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -0.00561239
JOSD1 Josephin domain containing 1 -0.00561223
MRPL2 mitochondrial ribosomal protein L2 -0.00560609
ENO2 enolase 2 (gamma, neuronal) -0.00560325
MNDA myeloid cell nuclear differentiation antigen -0.00560252
EHD2 EH-domain containing 2 -0.00559168
DEAF1 DEAF1 transcription factor -0.00558771
ACP3 acid phosphatase 3 -0.00556721
RPL36 ribosomal protein L36 -0.00556119
SREBF2 sterol regulatory element binding transcription factor 2 -0.00555071
CD59 CD59 molecule, complement regulatory protein -0.0055476
KRT17 keratin 17, type I -0.00554332
CHIT1 chitinase 1 (chitotriosidase) -0.00554296
SOD2 superoxide dismutase 2, mitochondrial -0.00554281
SERP1 stress-associated endoplasmic reticulum protein 1 -0.00552042
EREG epiregulin -0.00550468
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00546248
EPX eosinophil peroxidase -0.00545814
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -0.00545562
GTF2IRD1 GTF2I repeat domain containing 1 -0.00545497
SELENBP1 selenium binding protein 1 -0.00544076
MXI1 MAX interactor 1, dimerization protein -0.00543616
NDFIP1 Nedd4 family interacting protein 1 -0.00543278
WTAP Wilms tumor 1 associated protein -0.00542611
CD79B CD79b molecule, immunoglobulin-associated beta -0.00542123
PRDX4 peroxiredoxin 4 -0.00541551
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00540958
HINT1 histidine triad nucleotide binding protein 1 -0.00540866
EPHX2 epoxide hydrolase 2, cytoplasmic -0.00540619
PNPLA2 patatin-like phospholipase domain containing 2 -0.00540616
RXRA retinoid X receptor, alpha -0.00540197
FST follistatin -0.00539729
AUTS2 autism susceptibility candidate 2 -0.00537463
UROD uroporphyrinogen decarboxylase -0.00536946