TTLL1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description TTL family tubulin polyglutamylase complex subunit L1 (NCBI Entrez Gene Database, 25809)
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Genes

356 genes differentially expressed following the TTLL1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 4.23845
GLYAT glycine-N-acyltransferase 4.23845
PCDHGB3 protocadherin gamma subfamily B, 3 4.23845
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 4.23845
SLC25A45 solute carrier family 25, member 45 4.23845
LRRC53 leucine rich repeat containing 53 4.23845
MSS51 MSS51 mitochondrial translational activator 4.23845
PEX16 peroxisomal biogenesis factor 16 4.23845
OR2J2 olfactory receptor, family 2, subfamily J, member 2 4.23845
OLFM4 olfactomedin 4 4.23845
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 4.23845
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 4.23845
CARD16 caspase recruitment domain family, member 16 4.23845
OR52H1 olfactory receptor, family 52, subfamily H, member 1 4.23845
RXFP3 relaxin/insulin-like family peptide receptor 3 4.23845
CTRC chymotrypsin C (caldecrin) 4.23845
IZUMO3 IZUMO family member 3 4.23845
SLC46A3 solute carrier family 46, member 3 4.23845
OR52A5 olfactory receptor, family 52, subfamily A, member 5 4.23845
TMEM176B transmembrane protein 176B 4.23845
DNASE1L2 deoxyribonuclease I-like 2 4.23845
RSPO1 R-spondin 1 4.23845
DIRAS2 DIRAS family, GTP-binding RAS-like 2 4.23845
GPR26 G protein-coupled receptor 26 4.23845
SLC39A12 solute carrier family 39 (zinc transporter), member 12 4.23845
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.23845
CPLX3 complexin 3 4.23845
PRR22 proline rich 22 4.23845
NMUR2 neuromedin U receptor 2 4.23845
STEAP4 STEAP family member 4 4.23845
NWD2 NACHT and WD repeat domain containing 2 4.23845
KIAA1755 KIAA1755 4.23845
NPB neuropeptide B 4.23845
IL2RG interleukin 2 receptor, gamma 4.23845
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 4.23845
SLC23A3 solute carrier family 23, member 3 4.23845
HCRTR2 hypocretin (orexin) receptor 2 4.23845
ARSF arylsulfatase F 4.23845
UNC45B unc-45 homolog B (C. elegans) 4.23845
KLRK1 killer cell lectin-like receptor subfamily K, member 1 4.23845
CLEC5A C-type lectin domain family 5, member A 4.23845
S100A1 S100 calcium binding protein A1 4.23845
ICOS inducible T-cell co-stimulator 4.23845
PTK6 protein tyrosine kinase 6 4.23845
FGF9 fibroblast growth factor 9 4.23845
ALB albumin 4.23845
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 4.23845
SPI1 Spi-1 proto-oncogene 4.23845
C20ORF202 chromosome 20 open reading frame 202 4.23845
ACSL5 acyl-CoA synthetase long-chain family member 5 4.23845
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 4.23845
PAPOLB poly(A) polymerase beta (testis specific) 4.23845
ASB5 ankyrin repeat and SOCS box containing 5 4.23845
CFC1 cripto, FRL-1, cryptic family 1 4.23845
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 4.23845
GDF6 growth differentiation factor 6 4.23845
ACER1 alkaline ceramidase 1 4.23845
LDB3 LIM domain binding 3 4.23845
LOC124903372 uncharacterized LOC124903372 4.23845
CD8B2 CD8b2 molecule 4.23845
MCTS2 MCTS family member 2 4.23845
H3C3 H3 clustered histone 3 4.23845
RTL9 retrotransposon Gag like 9 4.23845
GMCL2 germ cell-less 2, spermatogenesis associated 4.23845
FYB1 FYN binding protein 1 4.23845
H3-5 H3.5 histone 4.23845
ROPN1B rhophilin associated tail protein 1B 4.23845
LRRC72 leucine rich repeat containing 72 4.23845
C9 complement component 9 4.23845
NR0B1 nuclear receptor subfamily 0, group B, member 1 4.23845
FRMD7 FERM domain containing 7 4.23845
FAM153A family with sequence similarity 153, member A 4.23845
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 4.23845
GPR75 G protein-coupled receptor 75 4.23845
TMPRSS11B transmembrane protease, serine 11B 4.23845
TMPRSS11A transmembrane protease, serine 11A 4.23845
ELF5 E74-like factor 5 (ets domain transcription factor) 4.23845
CST11 cystatin 11 4.23845
CD6 CD6 molecule 4.23845
FOXD1 forkhead box D1 4.23845
ZSWIM2 zinc finger, SWIM-type containing 2 4.23845
GSC goosecoid homeobox 4.23845
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 4.23845
PRR4 proline rich 4 (lacrimal) 4.23845
ARMS2 age-related maculopathy susceptibility 2 4.23845
GZMM granzyme M (lymphocyte met-ase 1) 4.23845
AWAT2 acyl-CoA wax alcohol acyltransferase 2 4.23845
TLR8 toll-like receptor 8 4.23845
IL5 interleukin 5 4.23845
ANXA10 annexin A10 4.23845
LY86 lymphocyte antigen 86 4.23845
CCDC87 coiled-coil domain containing 87 4.23845
DHRS7C dehydrogenase/reductase (SDR family) member 7C 4.23845
OR5AU1 olfactory receptor, family 5, subfamily AU, member 1 4.23845
POF1B premature ovarian failure, 1B 4.23845
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 4.23845
HMGB4 high mobility group box 4 4.23845
ARR3 arrestin 3, retinal (X-arrestin) 4.23845
CRYBB2 crystallin, beta B2 4.23845
CLRN2 clarin 2 4.23845
CTAGE9 CTAGE family, member 9 4.23845
CD244 CD244 molecule, natural killer cell receptor 2B4 4.23845
EDN3 endothelin 3 4.23845
MRLN myoregulin 4.23845
KCNK4 potassium channel, two pore domain subfamily K, member 4 4.23845
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 4.23845
ZMYND10 zinc finger, MYND-type containing 10 4.23845
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 4.23845
PLEKHS1 pleckstrin homology domain containing, family S member 1 4.23845
MAGEA11 melanoma antigen family A11 4.23845
BMX BMX non-receptor tyrosine kinase 4.23845
C11ORF97 chromosome 11 open reading frame 97 4.23845
IL17REL interleukin 17 receptor E-like 4.23845
CCL27 chemokine (C-C motif) ligand 27 4.23845
WNT7A wingless-type MMTV integration site family, member 7A 4.23845
ISLR immunoglobulin superfamily containing leucine-rich repeat 4.23845
OR4D2 olfactory receptor, family 4, subfamily D, member 2 4.23845
CLEC1A C-type lectin domain family 1, member A 4.23845
LRRC25 leucine rich repeat containing 25 4.23845
LGALS14 lectin, galactoside-binding, soluble, 14 4.23845
LY6G6D lymphocyte antigen 6 complex, locus G6D 4.23845
NKX6-1 NK6 homeobox 1 4.23845
WNT2 wingless-type MMTV integration site family member 2 4.23845
DRC1 dynein regulatory complex subunit 1 4.23845
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 4.23845
PRSS38 protease, serine, 38 4.23845
DLX2 distal-less homeobox 2 4.23845
SPHKAP SPHK1 interactor, AKAP domain containing 4.23845
KISS1 KiSS-1 metastasis-suppressor 4.23845
THBD thrombomodulin 4.23845
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 4.23845
SPATA9 spermatogenesis associated 9 4.23845
SAMD7 sterile alpha motif domain containing 7 4.23845
CTXN3 cortexin 3 4.23845
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 4.23845
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 4.23845
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 4.23845
SLC36A3 solute carrier family 36, member 3 4.23845
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 4.23845
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 4.23845
PODN podocan 4.23845
CETP cholesteryl ester transfer protein, plasma 4.23845
MAGEA12 melanoma antigen family A12 4.23845
FXYD4 FXYD domain containing ion transport regulator 4 4.23845
CDCP2 CUB domain containing protein 2 4.23845
NEUROD2 neuronal differentiation 2 4.23845
MRGPRX3 MAS-related GPR, member X3 4.23845
BPIFC BPI fold containing family C 4.23845
NXF3 nuclear RNA export factor 3 4.23845
NLRP3 NLR family, pyrin domain containing 3 4.23845
ANGPTL5 angiopoietin-like 5 4.23845
CLCA4 chloride channel accessory 4 4.23845
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 4.23845
PXT1 peroxisomal, testis specific 1 4.23845
PLGLB1 plasminogen-like B1 4.23845
MT1M metallothionein 1M 4.23845
MC5R melanocortin 5 receptor 4.23845
PRAP1 proline-rich acidic protein 1 4.23845
PRRX1 paired related homeobox 1 4.23845
ACOT11 acyl-CoA thioesterase 11 3.29527
TBXA2R thromboxane A2 receptor 3.25335
ZNF184 zinc finger protein 184 3.22946
TMEM236 transmembrane protein 236 3.07574
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 3.07574
POSTN periostin, osteoblast specific factor 3.07574
LRWD1 leucine-rich repeats and WD repeat domain containing 1 3.07574
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A 3.07574
FRK fyn-related Src family tyrosine kinase 3.07574
SLC61A1 solute carrier family 61 member 1 3.04458
UMPS uridine monophosphate synthetase 3.00004
MAK16 MAK16 homolog (S. cerevisiae) 2.99616
CA2 carbonic anhydrase II 2.99399
ZNF570 zinc finger protein 570 2.93142
LINC02798 long intergenic non-protein coding RNA 2798 2.93142
RNF152 ring finger protein 152 2.87779
CNN3 calponin 3, acidic 2.83817
OXT oxytocin/neurophysin I prepropeptide 2.80082
TCEAL4 transcription elongation factor A (SII)-like 4 2.78739
SH2D5 SH2 domain containing 5 2.76339
SYT4 synaptotagmin IV 2.64542
MTIF2 mitochondrial translational initiation factor 2 2.63866
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2.62114
NRDC nardilysin convertase 2.60047
ANKRD13B ankyrin repeat domain 13B 2.59289
TP53INP2 tumor protein p53 inducible nuclear protein 2 2.53938
JHY junctional cadherin complex regulator 2.52863
MESD mesoderm development LRP chaperone 2.51457
CA9 carbonic anhydrase IX 2.50051
VIM vimentin 2.49649
COL6A2 collagen, type VI, alpha 2 2.49044
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2.47495
APOO apolipoprotein O 2.47495
MORC3 MORC family CW-type zinc finger 3 2.46619
FAT4 FAT atypical cadherin 4 2.44513
USHBP1 Usher syndrome 1C binding protein 1 2.43573
ZNF569 zinc finger protein 569 2.41582
B4GAT1 beta-1,4-glucuronyltransferase 1 2.41557
IDO1 indoleamine 2,3-dioxygenase 1 2.40706
SUMO2 small ubiquitin-like modifier 2 2.3822
LHCGR luteinizing hormone/choriogonadotropin receptor 2.3822
TRMT61B tRNA methyltransferase 61B 2.35215
ARF1 ADP-ribosylation factor 1 2.34201
NDRG4 NDRG family member 4 2.32182
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.30765
MED4 mediator complex subunit 4 2.30212
SARAF store-operated calcium entry-associated regulatory factor 2.29853
UBXN1 UBX domain protein 1 2.29853
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.25696
RAB43 RAB43, member RAS oncogene family 2.25672
GAS6 growth arrest-specific 6 2.25584
ZC3H15 zinc finger CCCH-type containing 15 2.25333
FMO5 flavin containing monooxygenase 5 2.25294
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 2.24474
SH2D1B SH2 domain containing 1B 2.20096
LTK leukocyte receptor tyrosine kinase 2.19749
FH fumarate hydratase 2.17256
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.16692
GSTO1 glutathione S-transferase omega 1 2.16692
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.13512
HAUS5 HAUS augmin-like complex, subunit 5 2.13091
FAM221A family with sequence similarity 221, member A 2.13091
BTF3 basic transcription factor 3 2.11427
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 2.1103
TBC1D7-LOC100130357 TBC1D7-LOC100130357 readthrough 2.10538
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J 2.10538
SIDT2 SID1 transmembrane family, member 2 2.09607
DHCR7 7-dehydrocholesterol reductase 2.09607
SUMF2 sulfatase modifying factor 2 2.08874
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 2.07372
ALG10 ALG10, alpha-1,2-glucosyltransferase 2.07372
RMP64 ribonuclease MRP subunit p64 2.06604
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.05012
CXCL12 chemokine (C-X-C motif) ligand 12 2.02886
TMEM158 transmembrane protein 158 (gene/pseudogene) 2.01314

decreased expression

Symbol Name Standardized Value
NRGN neurogranin (protein kinase C substrate, RC3) -4.23845
ZNF467 zinc finger protein 467 -4.23845
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B -4.23845
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -4.23845
TNR tenascin R -4.23845
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -4.23845
CCDC144A coiled-coil domain containing 144A -4.23845
ACOT1 acyl-CoA thioesterase 1 -4.23845
POU2AF1 POU class 2 associating factor 1 -4.23845
FAM209B family with sequence similarity 209, member B -4.23845
MORC1 MORC family CW-type zinc finger 1 -4.23845
SPATA32 spermatogenesis associated 32 -4.23845
BTBD19 BTB (POZ) domain containing 19 -4.23845
PPP1R3A protein phosphatase 1, regulatory subunit 3A -4.23845
VPREB3 pre-B lymphocyte 3 -4.23845
TGM4 transglutaminase 4 -4.23845
AZGP1 alpha-2-glycoprotein 1, zinc-binding -4.23845
POU3F2 POU class 3 homeobox 2 -4.23845
FAM221B family with sequence similarity 221, member B -4.23845
CA1 carbonic anhydrase I -4.23845
HSF5 heat shock transcription factor family member 5 -4.23845
SCRG1 stimulator of chondrogenesis 1 -4.23845
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein -4.23845
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -4.23845
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -4.23845
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 -4.23845
GPR150 G protein-coupled receptor 150 -4.23845
C9ORF43 chromosome 9 open reading frame 43 -4.23845
SFTA2 surfactant associated 2 -4.23845
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 -4.23845
GOLGA8K golgin A8 family, member K -4.23845
SERTM2 serine rich and transmembrane domain containing 2 -4.23845
BTNL2 butyrophilin-like 2 -4.23845
MLANA melan-A -4.23845
TEX12 testis expressed 12 -4.23845
PCDHB12 protocadherin beta 12 -4.23845
BEAN1 brain expressed, associated with NEDD4, 1 -4.23845
ESR1 estrogen receptor 1 -4.23845
HK3 hexokinase 3 (white cell) -4.23845
IL31RA interleukin 31 receptor A -4.23845
MCF2L MCF.2 cell line derived transforming sequence-like -3.60644
TCL1B T-cell leukemia/lymphoma 1B -3.59517
INSYN1 inhibitory synaptic factor 1 -3.27319
RAB40A RAB40A, member RAS oncogene family -3.27319
AZU1 azurocidin 1 -3.27319
VCX variable charge, X-linked -3.27319
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -3.17088
PHAX phosphorylated adaptor for RNA export -3.16338
ETFDH electron-transferring-flavoprotein dehydrogenase -3.16307
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -3.09652
SIRT2 sirtuin 2 -3.04458
DESI2 desumoylating isopeptidase 2 -2.90922
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -2.89166
FLNC filamin C, gamma -2.87779
BTBD18 BTB (POZ) domain containing 18 -2.8696
TTC33 tetratricopeptide repeat domain 33 -2.83668
GPHRB golgi pH regulator B -2.83536
BHLHE41 basic helix-loop-helix family, member e41 -2.79036
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial -2.77964
TYMP thymidine phosphorylase -2.76339
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -2.744
EDARADD EDAR-associated death domain -2.744
FRS2 fibroblast growth factor receptor substrate 2 -2.73418
ZNF77 zinc finger protein 77 -2.68622
ZNF470 zinc finger protein 470 -2.63983
TTLL6 tubulin tyrosine ligase-like family member 6 -2.62938
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) -2.60909
KCTD8 potassium channel tetramerization domain containing 8 -2.60047
CCDC178 coiled-coil domain containing 178 -2.57346
ZNF253 zinc finger protein 253 -2.56241
PFAS phosphoribosylformylglycinamidine synthase -2.53662
CCDC74B coiled-coil domain containing 74B -2.49047
AHNAK2 AHNAK nucleoprotein 2 -2.49047
NOL10 nucleolar protein 10 -2.47978
TRIM52 tripartite motif containing 52 -2.45736
SCG3 secretogranin III -2.42635
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 -2.42635
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -2.4103
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.37563
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -2.35215
S100A2 S100 calcium binding protein A2 -2.35215
PAQR6 progestin and adipoQ receptor family member VI -2.34519
WWOX WW domain containing oxidoreductase -2.34042
LIPI lipase, member I -2.30881
PRICKLE3 prickle homolog 3 (Drosophila) -2.30734
ZNF367 zinc finger protein 367 -2.30376
IQCN IQ motif containing N -2.30376
PTPRU protein tyrosine phosphatase, receptor type, U -2.30352
MME membrane metallo-endopeptidase -2.30096
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -2.29853
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -2.29437
SYT7 synaptotagmin VII -2.27616
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -2.26775
ADRA2A adrenoceptor alpha 2A -2.25696
ZNF843 zinc finger protein 843 -2.25696
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) -2.25584
NTSR1 neurotensin receptor 1 (high affinity) -2.25584
C2CD4D C2 calcium-dependent domain containing 4D -2.25584
TAS2R20 taste receptor, type 2, member 20 -2.25333
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -2.25043
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -2.24543
KIRREL1 kirre like nephrin family adhesion molecule 1 -2.24474
TTLL1 tubulin tyrosine ligase-like family member 1 -2.22
CSNK2A1 casein kinase 2, alpha 1 polypeptide -2.22
RBM27 RNA binding motif protein 27 -2.19489
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -2.17103
CYB5R3 cytochrome b5 reductase 3 -2.16905
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -2.15495
KIF21B kinesin family member 21B -2.15024
TSPAN5 tetraspanin 5 -2.13189
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.13189
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -2.13091
WSB1 WD repeat and SOCS box containing 1 -2.11888
FBXL7 F-box and leucine-rich repeat protein 7 -2.11427
USP3 ubiquitin specific peptidase 3 -2.09857
HAPLN4 hyaluronan and proteoglycan link protein 4 -2.09607
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -2.07026
C14ORF132 chromosome 14 open reading frame 132 -2.06215
FCGBP Fc fragment of IgG binding protein -2.02886
CUL5 cullin 5 -2.02875
PANX1 pannexin 1 -2.02093
ANKMY1 ankyrin repeat and MYND domain containing 1 -2.0177