TTLL2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description tubulin tyrosine ligase like 2 (NCBI Entrez Gene Database, 83887)
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Genes

367 genes differentially expressed following the TTLL2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 4.03314
PON1 paraoxonase 1 4.03314
MILR1 mast cell immunoglobulin-like receptor 1 4.03314
TBX15 T-box 15 4.03314
APLN apelin 4.03314
GJB5 gap junction protein, beta 5, 31.1kDa 4.03314
FFAR4 free fatty acid receptor 4 4.03314
CSMD3 CUB and Sushi multiple domains 3 4.03314
SIGLEC5 sialic acid binding Ig-like lectin 5 4.03314
TUBB1 tubulin, beta 1 class VI 4.03314
GRIA2 glutamate receptor, ionotropic, AMPA 2 4.03314
FAM86B2 family with sequence similarity 86, member B2 4.03314
GFRA3 GDNF family receptor alpha 3 4.03314
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 4.03314
TRIM10 tripartite motif containing 10 4.03314
RNF151 ring finger protein 151 4.03314
GPR6 G protein-coupled receptor 6 4.03314
FOLR1 folate receptor 1 (adult) 4.03314
CD96 CD96 molecule 4.03314
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 4.03314
NR1H4 nuclear receptor subfamily 1, group H, member 4 4.03314
FAM167B family with sequence similarity 167, member B 4.03314
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 4.03314
IGFL4 IGF-like family member 4 4.03314
HCRTR1 hypocretin (orexin) receptor 1 4.03314
PRELP proline/arginine-rich end leucine-rich repeat protein 4.03314
DIRAS3 DIRAS family, GTP-binding RAS-like 3 4.03314
TAS2R8 taste receptor, type 2, member 8 4.03314
C19ORF67 chromosome 19 open reading frame 67 4.03314
BHMT2 betaine--homocysteine S-methyltransferase 2 4.03314
DIO3 deiodinase, iodothyronine, type III 4.03314
TAS2R19 taste receptor, type 2, member 19 4.03314
ACOT12 acyl-CoA thioesterase 12 4.03314
PRDM13 PR domain containing 13 4.03314
JCHAIN joining chain of multimeric IgA and IgM 4.03314
GALR3 galanin receptor 3 4.03314
CLEC14A C-type lectin domain family 14, member A 4.03314
ACY3 aminoacylase 3 4.03314
LVRN laeverin 4.03314
SPON2 spondin 2, extracellular matrix protein 4.03314
MMP20 matrix metallopeptidase 20 4.03314
CRYGA crystallin, gamma A 4.03314
UPB1 ureidopropionase, beta 4.03314
MYCT1 myc target 1 4.03314
MID2 midline 2 4.03314
ADGB androglobin 4.03314
CXCL2 chemokine (C-X-C motif) ligand 2 4.03314
ADAMTSL5 ADAMTS-like 5 4.03314
F7 coagulation factor VII (serum prothrombin conversion accelerator) 4.03314
SHISA7 shisa family member 7 4.03314
GLRA3 glycine receptor, alpha 3 4.03314
PSCA prostate stem cell antigen 4.03314
CPB2 carboxypeptidase B2 (plasma) 4.03314
ANKK1 ankyrin repeat and kinase domain containing 1 4.03314
HIC1 hypermethylated in cancer 1 4.03314
LOC124905976 uncharacterized LOC124905976 4.03314
AVPR1B arginine vasopressin receptor 1B 4.03314
PROP1 PROP paired-like homeobox 1 4.03314
CAPN9 calpain 9 4.03314
FRG2C FSHD region gene 2 family, member C 4.03314
PKD2L1 polycystic kidney disease 2-like 1 4.03314
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 4.03314
ASB4 ankyrin repeat and SOCS box containing 4 4.03314
WNT16 wingless-type MMTV integration site family, member 16 4.03314
DOK2 docking protein 2, 56kDa 4.03314
TSPAN1 tetraspanin 1 4.03314
IMPG1 interphotoreceptor matrix proteoglycan 1 4.03314
YIPF7 Yip1 domain family, member 7 4.03314
HAO2 hydroxyacid oxidase 2 (long chain) 4.03314
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 4.03314
CIMAP2 ciliary microtubule associated protein 2 4.03314
PRRT1B proline rich transmembrane protein 1B 4.03314
C4ORF54 chromosome 4 open reading frame 54 4.03314
SRARP steroid receptor associated and regulated protein 4.03314
EZHIP EZH inhibitory protein 4.03314
GSG1L2 GSG1 like 2 4.03314
CFAP276 cilia and flagella associated protein 276 4.03314
CCDC197 coiled-coil domain containing 197 4.03314
MEIOSIN meiosis initiator 4.03314
TAFA3 TAFA chemokine like family member 3 4.03314
ODAD1 outer dynein arm docking complex subunit 1 4.03314
OR8G5 olfactory receptor, family 8, subfamily G, member 5 4.03314
C15ORF62 chromosome 15 open reading frame 62 4.03314
TRPA1 transient receptor potential cation channel, subfamily A, member 1 4.03314
BBS5 Bardet-Biedl syndrome 5 4.03314
OR7C1 olfactory receptor, family 7, subfamily C, member 1 4.03314
MAGEB1 melanoma antigen family B1 4.03314
CLDN9 claudin 9 4.03314
PCDHB10 protocadherin beta 10 4.03314
CAPN14 calpain 14 4.03314
RAB41 RAB41, member RAS oncogene family 4.03314
OR2A5 olfactory receptor, family 2, subfamily A, member 5 4.03314
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 4.03314
RAET1L retinoic acid early transcript 1L 4.03314
TBX20 T-box 20 4.03314
AXDND1 axonemal dynein light chain domain containing 1 4.03314
C3ORF80 chromosome 3 open reading frame 80 4.03314
SCN10A sodium channel, voltage gated, type X alpha subunit 4.03314
MROH5 maestro heat-like repeat family member 5 4.03314
HNF1B HNF1 homeobox B 4.03314
LTB lymphotoxin beta (TNF superfamily, member 3) 4.03314
SOAT2 sterol O-acyltransferase 2 4.03314
IL16 interleukin 16 4.03314
OOSP1 oocyte secreted protein 1, pseudogene 4.03314
BARX2 BARX homeobox 2 4.03314
GJD4 gap junction protein, delta 4, 40.1kDa 4.03314
SPDYC speedy/RINGO cell cycle regulator family member C 4.03314
CFAP45 cilia and flagella associated protein 45 4.03314
KLRF1 killer cell lectin-like receptor subfamily F, member 1 4.03314
GUCA1C guanylate cyclase activator 1C 4.03314
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 4.03314
HHATL hedgehog acyltransferase-like 4.03314
CTAGE4 CTAGE family, member 4 4.03314
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 4.03314
ADAMDEC1 ADAM-like, decysin 1 4.03314
KLHL41 kelch-like family member 41 4.03314
GOLGA6A golgin A6 family, member A 4.03314
GOLGA6B golgin A6 family, member B 4.03314
HPX hemopexin 4.03314
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 4.03314
PLET1 placenta expressed transcript 1 4.03314
DQX1 DEAQ box RNA-dependent ATPase 1 4.03314
IDI2 isopentenyl-diphosphate delta isomerase 2 4.03314
STAB2 stabilin 2 4.03314
EFCAB9 EF-hand calcium binding domain 9 4.03314
IL17REL interleukin 17 receptor E-like 4.03314
FNDC1 fibronectin type III domain containing 1 4.03314
NIM1K NIM1 serine/threonine protein kinase 4.03314
IGFBP7 insulin-like growth factor binding protein 7 4.03314
SHOX2 short stature homeobox 2 4.03314
RNF112 ring finger protein 112 4.03314
DNAH12 dynein, axonemal, heavy chain 12 4.03314
DYDC1 DPY30 domain containing 1 4.03314
IRGM immunity-related GTPase family, M 4.03314
CCDC27 coiled-coil domain containing 27 4.03314
LMOD2 leiomodin 2 (cardiac) 4.03314
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 4.03314
MOBP myelin-associated oligodendrocyte basic protein 4.03314
GFY golgi-associated, olfactory signaling regulator 4.03314
GPR150 G protein-coupled receptor 150 4.03314
GBX2 gastrulation brain homeobox 2 4.03314
PPP1R27 protein phosphatase 1, regulatory subunit 27 4.03314
LRRN4 leucine rich repeat neuronal 4 4.03314
CNGB1 cyclic nucleotide gated channel beta 1 4.03314
TEX29 testis expressed 29 4.03314
TRIML1 tripartite motif family-like 1 4.03314
LY9 lymphocyte antigen 9 4.03314
DLX2 distal-less homeobox 2 4.03314
MUC16 mucin 16, cell surface associated 4.03314
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 4.03314
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 4.03314
FBXO40 F-box protein 40 4.03314
PCDHA13 protocadherin alpha 13 4.03314
EPGN epithelial mitogen 4.03314
SAMD5 sterile alpha motif domain containing 5 4.03314
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 4.03314
SCNN1B sodium channel, non voltage gated 1 beta subunit 4.03314
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 4.03314
CRTAM cytotoxic and regulatory T cell molecule 4.03314
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 4.03314
ZMYND12 zinc finger, MYND-type containing 12 4.03314
PTGDR prostaglandin D2 receptor (DP) 4.03314
NAT16 N-acetyltransferase 16 (GCN5-related, putative) 4.03314
CHRM1 cholinergic receptor, muscarinic 1 4.03314
APOL4 apolipoprotein L, 4 4.03314
ANKRD33 ankyrin repeat domain 33 4.03314
LPO lactoperoxidase 4.03314
CLCA4 chloride channel accessory 4 4.03314
PAQR6 progestin and adipoQ receptor family member VI 4.03314
NPAS4 neuronal PAS domain protein 4 4.03314
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 4.03314
SLC7A4 solute carrier family 7, member 4 4.03314
DNAH8 dynein, axonemal, heavy chain 8 4.03314
AZU1 azurocidin 1 4.03314
SHISA3 shisa family member 3 4.03314
LPA lipoprotein, Lp(a) 4.03314
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 4.03314
BARHL2 BarH-like homeobox 2 4.03314
RTN4RL1 reticulon 4 receptor-like 1 4.03314
AGBL4 ATP/GTP binding protein-like 4 4.03314
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 4.03314
TGM1 transglutaminase 1 4.03314
AGR2 anterior gradient 2 4.03314
ANKRD30B ankyrin repeat domain 30B 4.03314
SLCO1C1 solute carrier organic anion transporter family, member 1C1 4.03314
NPC1L1 NPC1-like 1 4.03314
POU5F2 POU domain class 5, transcription factor 2 4.03314
KCNK15 potassium channel, two pore domain subfamily K, member 15 4.03314
DCST2 DC-STAMP domain containing 2 4.03314
POTEE POTE ankyrin domain family, member E 4.03314
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 3.89311
ADORA1 adenosine A1 receptor 3.89311
ASB2 ankyrin repeat and SOCS box containing 2 3.89311
COL6A6 collagen, type VI, alpha 6 3.89311
PDE1B phosphodiesterase 1B, calmodulin-dependent 3.49087
SPPL2A signal peptide peptidase like 2A 3.40359
BTN3A2 butyrophilin, subfamily 3, member A2 3.32799
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 3.18844
ECH1 enoyl CoA hydratase 1, peroxisomal 3.12051
SMC5 structural maintenance of chromosomes 5 2.99991
SNAP47 synaptosomal-associated protein, 47kDa 2.90058
MED6 mediator complex subunit 6 2.84032
SCD5 stearoyl-CoA desaturase 5 2.77435
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 2.77435
CALY calcyon neuron-specific vesicular protein 2.77435
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 2.77435
SPMIP6 sperm microtubule inner protein 6 2.77435
MOG myelin oligodendrocyte glycoprotein 2.77435
TP73 tumor protein p73 2.77435
UBL3 ubiquitin-like 3 2.77435
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.77435
TBX6 T-box 6 2.77435
NLGN1 neuroligin 1 2.7327
ZNF510 zinc finger protein 510 2.73093
LINC02983 long intergenic non-protein coding RNA 2983 2.62714
LMNB2 lamin B2 2.58964
NASP nuclear autoantigenic sperm protein (histone-binding) 2.5441
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 2.48111
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 2.4797
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 2.47818
VWC2L von Willebrand factor C domain containing protein 2-like 2.46923
ARHGAP24 Rho GTPase activating protein 24 2.4145
PABPC4L poly(A) binding protein, cytoplasmic 4-like 2.40534
NIPSNAP3B nipsnap homolog 3B (C. elegans) 2.38981
SAPCD1 suppressor APC domain containing 1 2.38981
COL4A1 collagen, type IV, alpha 1 2.36539
CD4 CD4 molecule 2.35931
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 2.35788
DNMBP dynamin binding protein 2.34778
POPDC3 popeye domain containing 3 2.34778
XNDC1N XRCC1 N-terminal domain containing 1, N-terminal like 2.33698
FN3K fructosamine 3 kinase 2.31934
LYG2 lysozyme G-like 2 2.28845
ACRBP acrosin binding protein 2.27748
ARSJ arylsulfatase family, member J 2.24885
TMF1 TATA element modulatory factor 1 2.23871
GCA grancalcin, EF-hand calcium binding protein 2.19355
PTGR1 prostaglandin reductase 1 2.16962
ZNF81 zinc finger protein 81 2.15795
HLTF helicase-like transcription factor 2.14256
MYEF2 myelin expression factor 2 2.12953
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 2.09965
SLC35E3 solute carrier family 35, member E3 2.08256
DMAC1 distal membrane arm assembly component 1 2.06814
COG3 component of oligomeric golgi complex 3 2.06814
SDC3 syndecan 3 2.04978
RBM26 RNA binding motif protein 26 2.03446
HIPK3 homeodomain interacting protein kinase 3 2.00775
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2.00367
MCM4 minichromosome maintenance complex component 4 2.00367
NUCLEOLIN nucleolin multifunctional protein 2.00204

decreased expression

Symbol Name Standardized Value
ZACN zinc activated ligand-gated ion channel -4.03314
VCX variable charge, X-linked -4.03314
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -4.03314
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -4.03314
SGCZ sarcoglycan, zeta -4.03314
ZNF25 zinc finger protein 25 -4.03314
BTLA B and T lymphocyte associated -4.03314
FXYD2 FXYD domain containing ion transport regulator 2 -4.03314
NPIPB7 nuclear pore complex interacting protein family, member B7 -4.03314
VASN vasorin -4.03314
MYZAP myocardial zonula adherens protein -4.03314
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -4.03314
CLDN14 claudin 14 -4.03314
C5AR1 complement component 5a receptor 1 -4.03314
BRICD5 BRICHOS domain containing 5 -4.03314
CA13 carbonic anhydrase XIII -4.03314
BHLHE40 basic helix-loop-helix family, member e40 -4.03314
ADGRE3 adhesion G protein-coupled receptor E3 -4.03314
IGFL3 IGF-like family member 3 -4.03314
RNF17 ring finger protein 17 -4.03314
PLXDC1 plexin domain containing 1 -4.03314
SYCP1 synaptonemal complex protein 1 -4.03314
KBTBD6 kelch repeat and BTB (POZ) domain containing 6 -4.03314
PTTG2 pituitary tumor-transforming 2 -4.03314
ASB18 ankyrin repeat and SOCS box containing 18 -4.03314
LRTM3 leucine rich repeat transmembrane protein 3 -4.03314
ITK IL2-inducible T-cell kinase -4.03314
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 -4.03314
TMPRSS11F transmembrane protease, serine 11F -4.03314
CHRD chordin -4.03314
PLAAT4 phospholipase A and acyltransferase 4 -4.03314
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -4.03314
DEFB131B defensin beta 131B -4.03314
H4C6 H4 clustered histone 6 -4.03314
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 -4.03314
CSP2 CS pseudogene 2 -4.03314
N4BP2L1 NEDD4 binding protein 2-like 1 -4.03314
LSMEM1 leucine-rich single-pass membrane protein 1 -4.03314
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -4.03314
OPTC opticin -4.03314
TF transferrin -4.03314
CFP complement factor properdin -4.03314
SP140L SP140 nuclear body protein-like -4.03314
CCDC158 coiled-coil domain containing 158 -4.03314
TBX1 T-box 1 -4.03314
EBF4 early B-cell factor 4 -4.03314
DES desmin -4.03314
ZP3 zona pellucida glycoprotein 3 (sperm receptor) -3.50052
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 -3.43424
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I -3.38381
SWI5 SWI5 recombination repair homolog (yeast) -3.34303
HDDC3 HD domain containing 3 -3.20175
ZNF792 zinc finger protein 792 -3.14433
CFAP70 cilia and flagella associated protein 70 -3.14433
LIME1 Lck interacting transmembrane adaptor 1 -3.14433
SOX30 SRY (sex determining region Y)-box 30 -3.14433
PDE1A phosphodiesterase 1A, calmodulin-dependent -3.14433
TM2D3 TM2 domain containing 3 -2.96805
TRAPPC14 trafficking protein particle complex subunit 14 -2.91136
KLHL11 kelch-like family member 11 -2.73412
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -2.63687
MSR1 macrophage scavenger receptor 1 -2.63687
CNBD2 cyclic nucleotide binding domain containing 2 -2.63687
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -2.61638
SDR42E2 short chain dehydrogenase/reductase family 42E, member 2 -2.49364
ZDHHC24 zinc finger, DHHC-type containing 24 -2.48111
DMKN dermokine -2.47622
CLTCL1 clathrin, heavy chain-like 1 -2.4657
ARF5 ADP-ribosylation factor 5 -2.46075
CDNF cerebral dopamine neurotrophic factor -2.44422
SOX6 SRY (sex determining region Y)-box 6 -2.44081
MARCHF9 membrane associated ring-CH-type finger 9 -2.43855
IMP3 IMP3, U3 small nucleolar ribonucleoprotein -2.41405
ZNF770 zinc finger protein 770 -2.41254
IL11RA interleukin 11 receptor, alpha -2.41201
CD101 CD101 molecule -2.41201
SLC16A6 solute carrier family 16, member 6 -2.40534
METRN meteorin, glial cell differentiation regulator -2.39336
PCSK4 proprotein convertase subtilisin/kexin type 4 -2.37734
FAT4 FAT atypical cadherin 4 -2.36825
HMGN1 high mobility group nucleosome binding domain 1 -2.36539
SHROOM2 shroom family member 2 -2.36539
TBC1D25 TBC1 domain family, member 25 -2.36447
NKD2 naked cuticle homolog 2 (Drosophila) -2.36447
CPNE5 copine V -2.36447
LRTM1 leucine-rich repeats and transmembrane domains 1 -2.36325
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 -2.28845
GRIA4 glutamate receptor, ionotropic, AMPA 4 -2.27748
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -2.26641
ZNF649 zinc finger protein 649 -2.21588
ARHGAP45 Rho GTPase activating protein 45 -2.21072
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -2.16567
UBC ubiquitin C -2.13225
SAXO1 stabilizer of axonemal microtubules 1 -2.10863
SIK2 salt-inducible kinase 2 -2.09965
CCDC90B coiled-coil domain containing 90B -2.09207
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -2.08334
MICALL1 MICAL-like 1 -2.08312
ETFDH electron-transferring-flavoprotein dehydrogenase -2.08238
COPRS coordinator of PRMT5, differentiation stimulator -2.0798
RPS3A ribosomal protein S3A -2.07291
CNN1 calponin 1, basic, smooth muscle -2.07285
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) -2.06814
KATNBL1 katanin p80 subunit B-like 1 -2.06626
SGMS1 sphingomyelin synthase 1 -2.06611
TRAF3 TNF receptor-associated factor 3 -2.05647
PRKCZ protein kinase C, zeta -2.05256
PDS5A PDS5 cohesin associated factor A -2.04857
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -2.02526
OGG1 8-oxoguanine DNA glycosylase -2.02526
RUNDC3A RUN domain containing 3A -2.02526
RUMY1 regulator of UNG2 and MKLN1 interacting yippee protein 1 -2.02526
ARHGAP11A Rho GTPase activating protein 11A -2.01608
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.01588
EIF3D eukaryotic translation initiation factor 3, subunit D -2.01257
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 -2.00224