TTLL3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description tubulin tyrosine ligase-like family member 3| (NCBI Entrez Gene Database, 26140)
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Genes

304 genes differentially expressed following the TTLL3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GALR3 galanin receptor 3 2.64705
DLL4 delta-like 4 (Drosophila) 2.64705
GSC2 goosecoid homeobox 2 2.64705
CRYBA4 crystallin, beta A4 2.64705
RIPK4 receptor-interacting serine-threonine kinase 4 2.64705
C1QTNF8 C1q and tumor necrosis factor related protein 8 2.64705
KIAA1210 KIAA1210 2.64705
C11ORF87 chromosome 11 open reading frame 87 2.64705
APOH apolipoprotein H (beta-2-glycoprotein I) 2.64705
TSPAN8 tetraspanin 8 2.64705
CA1 carbonic anhydrase I 2.64705
PNMA8B PNMA family member 8B 2.64705
HSPA1L heat shock 70kDa protein 1-like 2.64705
ADAM12 ADAM metallopeptidase domain 12 2.64705
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.64705
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 2.64705
TMC2 transmembrane channel-like 2 2.64705
CLEC2L C-type lectin domain family 2, member L 2.64705
FMO3 flavin containing monooxygenase 3 2.64705
NCF4 neutrophil cytosolic factor 4, 40kDa 2.64014
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 2.64014
SOX14 SRY (sex determining region Y)-box 14 2.64014
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.64014
LAX1 lymphocyte transmembrane adaptor 1 2.64014
NAPSA napsin A aspartic peptidase 2.64014
LRRD1 leucine-rich repeats and death domain containing 1 2.64014
EPPIN epididymal peptidase inhibitor 2.64014
TRIM15 tripartite motif containing 15 2.64014
NANOS3 nanos homolog 3 (Drosophila) 2.64014
STEAP4 STEAP family member 4 2.64014
SPINK4 serine peptidase inhibitor, Kazal type 4 2.64014
PAX3 paired box 3 2.64014
NCKAP1L NCK-associated protein 1-like 2.64014
TUBB1 tubulin, beta 1 class VI 2.64014
HMX3 H6 family homeobox 3 2.64014
KLLN killin, p53-regulated DNA replication inhibitor 2.64014
LGALS2 lectin, galactoside-binding, soluble, 2 2.64014
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.64014
ATOH8 atonal homolog 8 (Drosophila) 2.64014
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 2.64014
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) 2.64014
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.64014
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.64014
CX3CR1 chemokine (C-X3-C motif) receptor 1 2.64014
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 2.64014
PARM1 prostate androgen-regulated mucin-like protein 1 2.64014
BIRC3 baculoviral IAP repeat containing 3 2.64014
FAM221B family with sequence similarity 221, member B 2.64014
GFI1 growth factor independent 1 transcription repressor 2.64014
C19ORF67 chromosome 19 open reading frame 67 2.64014
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.64014
LOC105378220 macrophage receptor MARCO-like 2.64014
SPATA31G1 SPATA31 subfamily G member 1 2.64014
VSIR V-set immunoregulatory receptor 2.64014
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.64014
DEFB108B defensin, beta 108B 2.64014
PTH1R parathyroid hormone 1 receptor 2.64014
ROPN1L rhophilin associated tail protein 1-like 2.64014
CLDN14 claudin 14 2.64014
LOC124900192 uncharacterized LOC124900192 2.64014
TREX2 three prime repair exonuclease 2 2.64014
TBXT T-box transcription factor T 2.64014
SPEM2 SPEM family member 2 2.64014
GARIN6 golgi associated RAB2 interactor family member 6 2.64014
ZC3H11C zinc finger CCCH-type containing 11C 2.64014
FOXL3 forkhead box L3 2.64014
LINC02798 long intergenic non-protein coding RNA 2798 2.64014
LOC124903372 uncharacterized LOC124903372 2.64014
SMIM45 small integral membrane protein 45 2.64014
C20ORF204 chromosome 20 open reading frame 204 2.64014
GLYATL1B glycine-N-acyltransferase like 1B 2.64014
TMEM225B transmembrane protein 225B 2.64014
SAG S-antigen; retina and pineal gland (arrestin) 2.64014
FOXC2 forkhead box C2 2.64014
SLAMF1 signaling lymphocytic activation molecule family member 1 2.64014
ADGRG1 adhesion G protein-coupled receptor G1 2.64014
NHLRC4 NHL repeat containing 4 2.64014
HAPLN2 hyaluronan and proteoglycan link protein 2 2.64014
IL31RA interleukin 31 receptor A 2.64014
SNX20 sorting nexin 20 2.64014
ARL5C ADP-ribosylation factor-like 5C 2.64014
PLVAP plasmalemma vesicle associated protein 2.64014
TBX3 T-box 3 2.64014
PIWIL3 piwi-like RNA-mediated gene silencing 3 2.64014
CCR3 chemokine (C-C motif) receptor 3 2.64014
ZNF441 zinc finger protein 441 2.64014
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 2.64014
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.64014
SYT15 synaptotagmin XV 2.64014
RNF183 ring finger protein 183 2.64014
ZAR1L zygote arrest 1-like 2.64014
VCX3A variable charge, X-linked 3A 2.64014
RGS21 regulator of G-protein signaling 21 2.64014
AGTR1 angiotensin II receptor, type 1 2.64014
TMEM132C transmembrane protein 132C 2.64014
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.64014
KLHL6 kelch-like family member 6 2.64014
CTAGE15 CTAGE family, member 15 2.64014
CDC20B cell division cycle 20B 2.64014
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 2.64014
CTSO cathepsin O 2.64014
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.64014
LRRC43 leucine rich repeat containing 43 2.64014
FNDC8 fibronectin type III domain containing 8 2.64014
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.64014
EBF3 early B-cell factor 3 2.64014
FAT2 FAT atypical cadherin 2 2.64014
MRPS17 mitochondrial ribosomal protein S17 2.64014
QRFP pyroglutamylated RFamide peptide 2.64014
PYHIN1 pyrin and HIN domain family, member 1 2.64014
CHIT1 chitinase 1 (chitotriosidase) 2.64014
BTNL8 butyrophilin-like 8 2.64014
CXCR6 chemokine (C-X-C motif) receptor 6 2.64014
SMIM17 small integral membrane protein 17 2.64014
CCL14 chemokine (C-C motif) ligand 14 2.64014
PCDHGA3 protocadherin gamma subfamily A, 3 2.64014
C22ORF42 chromosome 22 open reading frame 42 2.64014
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.64014
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.64014
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.64014
LY96 lymphocyte antigen 96 2.64014
FGG fibrinogen gamma chain 2.64014
SH3BGRL SH3 domain binding glutamate-rich protein like 2.64014
ARL13A ADP-ribosylation factor-like 13A 2.64014
TF transferrin 2.64014
RBM24 RNA binding motif protein 24 2.64014
ERICH6B glutamate-rich 6B 2.64014
ANKRD55 ankyrin repeat domain 55 2.64014
PPIF peptidylprolyl isomerase F 2.64014
HMGB4 high mobility group box 4 2.64014
LRRC32 leucine rich repeat containing 32 2.64014
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.64014
ESPNL espin-like 2.64014
FKBP1C FK506 binding protein 1C 2.64014
SNTN sentan, cilia apical structure protein 2.64014
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.64014
PF4V1 platelet factor 4 variant 1 2.64014
NPY2R neuropeptide Y receptor Y2 2.64014
MMEL1 membrane metallo-endopeptidase-like 1 2.64014
IL33 interleukin 33 2.64014
CLEC2A C-type lectin domain family 2, member A 2.64014
CD3D CD3d molecule, delta (CD3-TCR complex) 2.64014
CD22 CD22 molecule 2.64014
FXYD3 FXYD domain containing ion transport regulator 3 2.64014
FAM81B family with sequence similarity 81, member B 2.64014
SIDT1 SID1 transmembrane family, member 1 2.64014
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2.64014
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.64014
EPHB3 EPH receptor B3 2.64014
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.64014
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 2.64014
FAIM2 Fas apoptotic inhibitory molecule 2 2.64014
MAGEB17 melanoma antigen family B17 2.64014
BOLL boule-like RNA-binding protein 2.64014
ERVV-1 endogenous retrovirus group V, member 1 2.64014
FOXF1 forkhead box F1 2.64014
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.64014
POTEF POTE ankyrin domain family, member F 2.64014
NUTM2A NUT family member 2A 2.64014
KLHDC1 kelch domain containing 1 2.64014
ABLIM3 actin binding LIM protein family, member 3 2.64014
HEMGN hemogen 2.64014
CDC42 cell division cycle 42 2.62166
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 2.57591
CFAP54 cilia and flagella associated 54 2.5757
SLC67A1 solute carrier family 67 member 1 2.5757
FAM229A family with sequence similarity 229, member A 2.5757
POLRMT polymerase (RNA) mitochondrial (DNA directed) 2.53964
KEL Kell blood group, metallo-endopeptidase 2.53839
LRATD2 LRAT domain containing 2 2.53499
RAB15 RAB15, member RAS oncogene family 2.5216
MRPS18C mitochondrial ribosomal protein S18C 2.49818
CABLES2 Cdk5 and Abl enzyme substrate 2 2.49518
C1ORF198 chromosome 1 open reading frame 198 2.49518
FSD1L fibronectin type III and SPRY domain containing 1-like 2.49518
JMJD7 jumonji domain containing 7 2.47179
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 2.46862
EEA1 early endosome antigen 1 2.4473
CRACDL CRACD like 2.42068
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.40688
ZNF765 zinc finger protein 765 2.38313
COA7 cytochrome c oxidase assembly factor 7 (putative) 2.38106
MTCL1 microtubule crosslinking factor 1 2.3622
PLD2 phospholipase D2 2.3622
CHEK1 checkpoint kinase 1 2.3622
ZNF358 zinc finger protein 358 2.32846
ATM ATM serine/threonine kinase 2.30832
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 2.30832
ECT2L epithelial cell transforming 2 like 2.30832
PTPRK protein tyrosine phosphatase, receptor type, K 2.3078
TMEM231 transmembrane protein 231 2.29301
NOTCH3 notch 3 2.29163
FBXO31 F-box protein 31 2.24896
FLRT2 fibronectin leucine rich transmembrane protein 2 2.2388
RAP1GAP2 RAP1 GTPase activating protein 2 2.2364
TTLL9 tubulin tyrosine ligase-like family member 9 2.23197
ZNF582 zinc finger protein 582 2.23044
UCKL1 uridine-cytidine kinase 1-like 1 2.23044
SUSD4 sushi domain containing 4 2.23044
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 2.18839
ZNF711 zinc finger protein 711 2.17245
HOMER2 homer scaffolding protein 2 2.1609
SUGP2 SURP and G patch domain containing 2 2.14056
COQ8A coenzyme Q8A 2.10876
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.09112
SOCS2 suppressor of cytokine signaling 2 2.09112
RINT1 RAD50 interactor 1 2.06891
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.06801
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.06517
RSPO4 R-spondin 4 2.06517
TMEM14C transmembrane protein 14C 2.06375
PTBP3 polypyrimidine tract binding protein 3 2.06184
FNTA farnesyltransferase, CAAX box, alpha 2.0519
CFAP298 cilia and flagella associated protein 298 2.04373
COA5 cytochrome c oxidase assembly factor 5 2.03166
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.02486
ACACA acetyl-CoA carboxylase alpha 2.00682

decreased expression

Symbol Name Standardized Value
AFG2A AFG2 AAA ATPase homolog A -2.64705
TOX thymocyte selection-associated high mobility group box -2.64705
TGFBR3L transforming growth factor, beta receptor III-like -2.64705
CFAP90 cilia and flagella associated protein 90 -2.64014
PMEPA1 prostate transmembrane protein, androgen induced 1 -2.64014
MRPL23 mitochondrial ribosomal protein L23 -2.64014
ZNF696 zinc finger protein 696 -2.64014
TIGD6 tigger transposable element derived 6 -2.64014
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.64014
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) -2.64014
ATG9B autophagy related 9B -2.64014
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -2.6169
AGBL5 ATP/GTP binding protein-like 5 -2.61504
SMC4 structural maintenance of chromosomes 4 -2.51898
GOLT1B golgi transport 1B -2.50212
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 -2.49518
DCST1 DC-STAMP domain containing 1 -2.49518
CES3 carboxylesterase 3 -2.49518
THSD7A thrombospondin, type I, domain containing 7A -2.49518
NR1I3 nuclear receptor subfamily 1, group I, member 3 -2.49518
C6ORF118 chromosome 6 open reading frame 118 -2.49518
HES4 hes family bHLH transcription factor 4 -2.49518
TMEM229A transmembrane protein 229A -2.49518
LIX1 Lix1 homolog (chicken) -2.49518
ARSI arylsulfatase family, member I -2.49518
ZNF648 zinc finger protein 648 -2.49518
HTRA4 HtrA serine peptidase 4 -2.49518
SCIN scinderin -2.49518
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 -2.49518
KLK14 kallikrein-related peptidase 14 -2.49518
ITGA11 integrin, alpha 11 -2.49518
ANKRD53 ankyrin repeat domain 53 -2.49518
ATP10B ATPase, class V, type 10B -2.49518
CISH cytokine inducible SH2-containing protein -2.49518
CLUL1 clusterin-like 1 (retinal) -2.49518
EIF4E1B eukaryotic translation initiation factor 4E family member 1B -2.49518
MGAM maltase-glucoamylase -2.49518
GSDMA gasdermin A -2.49518
FZD5 frizzled class receptor 5 -2.49518
PNMA8C PNMA family member 8C -2.49518
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 -2.49518
LOC124902436 talanin -2.49518
FYB2 FYN binding protein 2 -2.49518
TMOD4 tropomodulin 4 (muscle) -2.49518
SUN3 Sad1 and UNC84 domain containing 3 -2.49518
IQGAP1 IQ motif containing GTPase activating protein 1 -2.46862
SCT secretin -2.44038
GPR20 G protein-coupled receptor 20 -2.44038
AKAP3 A kinase (PRKA) anchor protein 3 -2.44038
EIF3B eukaryotic translation initiation factor 3, subunit B -2.42068
AIRIM AFG2 interacting ribosome maturation factor -2.3622
ANKRD31 ankyrin repeat domain 31 -2.36075
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.32932
ADCY7 adenylate cyclase 7 -2.31261
CATSPERQ catsper channel auxiliary subunit theta -2.30832
FIGN fidgetin -2.30832
AZU1 azurocidin 1 -2.30832
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit -2.30832
SOX7 SRY (sex determining region Y)-box 7 -2.30832
MERTK MER proto-oncogene, tyrosine kinase -2.29163
NCBP2 nuclear cap binding protein subunit 2, 20kDa -2.29163
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 -2.28371
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -2.2767
RIMS1 regulating synaptic membrane exocytosis 1 -2.27199
TRIM68 tripartite motif containing 68 -2.25828
STOX2 storkhead box 2 -2.23658
DBP D site of albumin promoter (albumin D-box) binding protein -2.22844
CCDC13 coiled-coil domain containing 13 -2.22844
VARS1 valyl-tRNA synthetase 1 -2.22669
CTNNA3 catenin (cadherin-associated protein), alpha 3 -2.19836
FIBCD1 fibrinogen C domain containing 1 -2.15438
SCART1 scavenger receptor protein family member -2.11204
STIMATE STIM activating enhancer -2.10943
ISOC2 isochorismatase domain containing 2 -2.10138
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -2.08975
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F -2.08005
MATN4 matrilin 4 -2.07781
NFE2L2 nuclear factor, erythroid 2-like 2 -2.06517
IRAK2 interleukin-1 receptor-associated kinase 2 -2.06517
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K -2.06517
SMC3 structural maintenance of chromosomes 3 -2.06184
CWC22 CWC22 spliceosome-associated protein -2.06013
SLC44A4 solute carrier family 44, member 4 -2.06013
EGF epidermal growth factor -2.02906
RPS24 ribosomal protein S24 -2.02863
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -2.02486
VBP1 von Hippel-Lindau binding protein 1 -2.01714