TTNPB-223 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

193 genes differentially expressed following the TTNPB-223 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ADAM20 ADAM metallopeptidase domain 20
ADAM22 ADAM metallopeptidase domain 22
ADAP1 ArfGAP with dual PH domains 1
ADARB1 adenosine deaminase, RNA-specific, B1
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AQP1 aquaporin 1 (Colton blood group)
BDKRB2 bradykinin receptor B2
BEST2 bestrophin 2
BIN1 bridging integrator 1
BMP8B bone morphogenetic protein 8b
BRCA2 breast cancer 2, early onset
BTG2 BTG family, member 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF26 chromosome 7 open reading frame 26
CADM3 cell adhesion molecule 3
CARTPT CART prepropeptide
CD6 CD6 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK3 cyclin-dependent kinase 3
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CFAP70 cilia and flagella associated protein 70
CLMN calmin (calponin-like, transmembrane)
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CORO2A coronin, actin binding protein, 2A
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DUS2 dihydrouridine synthase 2
DYSF dysferlin
EFNB3 ephrin-B3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FAM188A family with sequence similarity 188, member A
FNDC3A fibronectin type III domain containing 3A
FOXC1 forkhead box C1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GUCA1B guanylate cyclase activator 1B (retina)
HOXA1 homeobox A1
HOXA5 homeobox A5
HOXB7 homeobox B7
HUS1 HUS1 checkpoint homolog (S. pombe)
IFNA21 interferon, alpha 21
IL1B interleukin 1, beta
KRT75 keratin 75, type II
LAMA3 laminin, alpha 3
LIAS lipoic acid synthetase
LOC100127972 uncharacterized LOC100127972
MAGEA5 melanoma antigen family A5
MAOA monoamine oxidase A
MINK1 misshapen-like kinase 1
MOB3B MOB kinase activator 3B
MPZL2 myelin protein zero-like 2
MRPL41 mitochondrial ribosomal protein L41
MYL10 myosin, light chain 10, regulatory
MYO1F myosin IF
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PARVA parvin, alpha
PCTP phosphatidylcholine transfer protein
PDE4DIP phosphodiesterase 4D interacting protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PRB1 proline-rich protein BstNI subfamily 1
PSAT1 phosphoserine aminotransferase 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RFPL2 ret finger protein-like 2
RPL35A ribosomal protein L35a
SAT1 spermidine/spermine N1-acetyltransferase 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEZ6L seizure related 6 homolog (mouse)-like
SKAP2 src kinase associated phosphoprotein 2
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC38A3 solute carrier family 38, member 3
SOX9 SRY (sex determining region Y)-box 9
SPON1 spondin 1, extracellular matrix protein
SRPK2 SRSF protein kinase 2
STK11 serine/threonine kinase 11
STRA6 stimulated by retinoic acid 6
TCEA2 transcription elongation factor A (SII), 2
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGM5 transglutaminase 5
TMEM161A transmembrane protein 161A
TMPRSS4 transmembrane protease, serine 4
TRAK1 trafficking protein, kinesin binding 1
TRIL TLR4 interactor with leucine-rich repeats
TRIM2 tripartite motif containing 2
TRIM31 tripartite motif containing 31
TRIM9 tripartite motif containing 9
VIPR2 vasoactive intestinal peptide receptor 2
WDR1 WD repeat domain 1
WDR18 WD repeat domain 18
WSCD1 WSC domain containing 1
ZNF3 zinc finger protein 3
ZNF460 zinc finger protein 460

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADCK4 aarF domain containing kinase 4
ANKRD36B ankyrin repeat domain 36B
ASIP agouti signaling protein
ATF7 activating transcription factor 7
BBC3 BCL2 binding component 3
BEND5 BEN domain containing 5
BEST1 bestrophin 1
C16ORF59 chromosome 16 open reading frame 59
C1ORF159 chromosome 1 open reading frame 159
C22ORF29 chromosome 22 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CBX2 chromobox homolog 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLIP3 CAP-GLY domain containing linker protein 3
CLTCL1 clathrin, heavy chain-like 1
CNGB3 cyclic nucleotide gated channel beta 3
COBL cordon-bleu WH2 repeat protein
CPTP ceramide-1-phosphate transfer protein
CRYAA crystallin, alpha A
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAGLA diacylglycerol lipase, alpha
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
EAF2 ELL associated factor 2
ECE2 endothelin converting enzyme 2
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO22 F-box protein 22
FGFBP1 fibroblast growth factor binding protein 1
FZD4 frizzled class receptor 4
GATA1 GATA binding protein 1 (globin transcription factor 1)
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPC3 glypican 3
GRTP1 growth hormone regulated TBC protein 1
HOXD11 homeobox D11
IL18RAP interleukin 18 receptor accessory protein
IL36RN interleukin 36 receptor antagonist
IL4R interleukin 4 receptor
IRS4 insulin receptor substrate 4
KLHL3 kelch-like family member 3
KREMEN2 kringle containing transmembrane protein 2
LEFTY2 left-right determination factor 2
LHX2 LIM homeobox 2
LHX6 LIM homeobox 6
LMTK1 lemur tail kinase 1
LOC100131510 uncharacterized LOC100131510
LOC257152 uncharacterized LOC257152
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK3 mitogen-activated protein kinase 3
MARC1 mitochondrial amidoxime reducing component 1
MGC2889 uncharacterized protein MGC2889
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYL1 myosin, light chain 1, alkali; skeletal, fast
NELFE negative elongation factor complex member E
NXPH3 neurexophilin 3
OVOL1 ovo-like zinc finger 1
PARP8 poly (ADP-ribose) polymerase family, member 8
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PGBD5 piggyBac transposable element derived 5
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
POMT2 protein-O-mannosyltransferase 2
PRKG2 protein kinase, cGMP-dependent, type II
PRSS53 protease, serine, 53
PYGB phosphorylase, glycogen; brain
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
REPS2 RALBP1 associated Eps domain containing 2
S100A1 S100 calcium binding protein A1
SAMHD1 SAM domain and HD domain 1
SCARA3 scavenger receptor class A, member 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLURP1 secreted LY6/PLAUR domain containing 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPTBN2 spectrin, beta, non-erythrocytic 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAB2 stabilin 2
SURF2 surfeit 2
TET3 tet methylcytosine dioxygenase 3
TMEM121 transmembrane protein 121
TWISTNB TWIST neighbor
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT3 wingless-type MMTV integration site family, member 3
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
XYLT2 xylosyltransferase II
ZFP36 ZFP36 ring finger protein
ZNF32 zinc finger protein 32
ZNF35 zinc finger protein 35
ZNF446 zinc finger protein 446
ZNF654 zinc finger protein 654
ZNF668 zinc finger protein 668