TUT1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description terminal uridylyl transferase 1, U6 snRNA-specific|This gene encodes a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. The encoded enzyme specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation.[provided by RefSeq, Apr 2009] (NCBI Entrez Gene Database, 64852)
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Genes

249 genes differentially expressed following the TUT1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
FGF8 fibroblast growth factor 8 (androgen-induced) 2.56784
TMEM174 transmembrane protein 174 2.56784
ADTRP androgen-dependent TFPI-regulating protein 2.56784
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.56784
RIMBP2 RIMS binding protein 2 2.56784
HYAL4 hyaluronoglucosaminidase 4 2.56784
OR2B6 olfactory receptor, family 2, subfamily B, member 6 2.56784
EPPIN epididymal peptidase inhibitor 2.56784
TSGA13 testis specific, 13 2.56784
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.56784
FGL2 fibrinogen-like 2 2.56784
BTC betacellulin 2.56784
SCN2B sodium channel, voltage gated, type II beta subunit 2.56784
ZNF208 zinc finger protein 208 2.56784
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.56784
ASB15 ankyrin repeat and SOCS box containing 15 2.56784
PAX8 paired box 8 2.56784
UCN2 urocortin 2 2.56784
RSPO3 R-spondin 3 2.56784
EVPL envoplakin 2.56784
KCNU1 potassium channel, subfamily U, member 1 2.56784
ACY3 aminoacylase 3 2.56784
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 2.56784
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.56784
FAM216B family with sequence similarity 216, member B 2.56784
MMP21 matrix metallopeptidase 21 2.56784
LRRC61 leucine rich repeat containing 61 2.56784
LGI1 leucine-rich, glioma inactivated 1 2.56784
F2 coagulation factor II (thrombin) 2.56784
DLX4 distal-less homeobox 4 2.56784
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 2.56784
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.56784
FAM221B family with sequence similarity 221, member B 2.56784
SLC23A3 solute carrier family 23, member 3 2.56784
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 2.56784
ZACN zinc activated ligand-gated ion channel 2.56784
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 2.56784
PAPOLA poly(A) polymerase alpha 2.56784
FOXN4 forkhead box N4 2.56784
ACER1 alkaline ceramidase 1 2.56784
ADGRG3 adhesion G protein-coupled receptor G3 2.56784
GIPC3 GIPC PDZ domain containing family, member 3 2.56784
ANGPTL8 angiopoietin like 8 2.56784
MYORG myogenesis regulating glycosidase (putative) 2.56784
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) 2.56784
CABCOCO1 ciliary associated calcium binding coiled-coil 1 2.56784
H2BW1 H2B.W histone 1 2.56784
H4C14 H4 clustered histone 14 2.56784
CTXND1 cortexin domain containing 1 2.56784
CFAP97D2 CFAP97 domain containing 2 2.56784
CIMAP1B ciliary microtubule associated protein 1B 2.56784
WNT9B wingless-type MMTV integration site family, member 9B 2.56784
ZAR1L zygote arrest 1-like 2.56784
PLEK2 pleckstrin 2 2.56784
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 2.56784
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.56784
FPR1 formyl peptide receptor 1 2.56784
ZNF436 zinc finger protein 436 2.56784
RAB44 RAB44, member RAS oncogene family 2.56784
ARL5C ADP-ribosylation factor-like 5C 2.56784
C1ORF87 chromosome 1 open reading frame 87 2.56784
TUBA3D tubulin, alpha 3d 2.56784
IRF8 interferon regulatory factor 8 2.56784
CATSPER1 cation channel, sperm associated 1 2.56784
CXCL14 chemokine (C-X-C motif) ligand 14 2.56784
IL5 interleukin 5 2.56784
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 2.56784
GSC goosecoid homeobox 2.56784
FGFBP2 fibroblast growth factor binding protein 2 2.56784
LOC124906892 uncharacterized LOC124906892 2.56784
TPH1 tryptophan hydroxylase 1 2.56784
IL1B interleukin 1, beta 2.56784
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.56784
CDRT15L2 CMT1A duplicated region transcript 15-like 2 2.56784
KLK7 kallikrein-related peptidase 7 2.56784
TBPL2 TATA box binding protein like 2 2.56784
AGR2 anterior gradient 2 2.56784
NUTM2F NUT family member 2F 2.56784
NUTM2D NUT family member 2D 2.56784
CDC20B cell division cycle 20B 2.56784
COL9A2 collagen, type IX, alpha 2 2.56784
GLT6D1 glycosyltransferase 6 domain containing 1 2.56784
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.56784
RERGL RERG/RAS-like 2.56784
CH25H cholesterol 25-hydroxylase 2.56784
DYDC1 DPY30 domain containing 1 2.56784
SNCB synuclein, beta 2.56784
TEKT2 tektin 2 (testicular) 2.56784
TSPAN8 tetraspanin 8 2.56784
SH2D4B SH2 domain containing 4B 2.56784
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 2.56784
TMEM204 transmembrane protein 204 2.56784
GOLGA6B golgin A6 family, member B 2.56784
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.56784
TAS2R50 taste receptor, type 2, member 50 2.56784
ANKRD61 ankyrin repeat domain 61 2.56784
ADORA3 adenosine A3 receptor 2.56784
CERKL ceramide kinase-like 2.56784
CST4 cystatin S 2.56784
WFDC10A WAP four-disulfide core domain 10A 2.56784
FCRL1 Fc receptor-like 1 2.56784
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.56784
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.56784
DNAH8 dynein, axonemal, heavy chain 8 2.56784
RP1 retinitis pigmentosa 1 (autosomal dominant) 2.56784
RAB7B RAB7B, member RAS oncogene family 2.56784
NMBR neuromedin B receptor 2.56784
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.56784
GPR150 G protein-coupled receptor 150 2.56784
GPR149 G protein-coupled receptor 149 2.56784
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.56784
TRIML1 tripartite motif family-like 1 2.56784
DKK2 dickkopf WNT signaling pathway inhibitor 2 2.56784
GJC2 gap junction protein, gamma 2, 47kDa 2.56784
ANGPTL5 angiopoietin-like 5 2.56784
TAS2R43 taste receptor, type 2, member 43 2.56784
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.56784
PENK proenkephalin 2.56784
TRPM1 transient receptor potential cation channel, subfamily M, member 1 2.56784
LHX9 LIM homeobox 9 2.56784
BCL2L15 BCL2-like 15 2.56784
FEV FEV (ETS oncogene family) 2.56784
IL10RA interleukin 10 receptor, alpha 2.56784
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.56784
RTN4RL1 reticulon 4 receptor-like 1 2.56784
CACFD1 calcium channel flower domain containing 1 2.52884
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.52884
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 2.4978
KRT86 keratin 86, type II 2.47487
LARS1 leucyl-tRNA synthetase 1 2.32257
RNF123 ring finger protein 123 2.31405
AVP arginine vasopressin 2.31405
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 2.31405
KRTCAP3 keratinocyte associated protein 3 2.31405
CRELD2 cysteine-rich with EGF-like domains 2 2.31405
TXNDC17 thioredoxin domain containing 17 2.31405
RBPMS RNA binding protein with multiple splicing 2.31405
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2.31405
EMC1 ER membrane protein complex subunit 1 2.31405
RALBP1 ralA binding protein 1 2.30614
ZNF813 zinc finger protein 813 2.29734
ARMCX5 armadillo repeat containing, X-linked 5 2.26836
RPLP0 ribosomal protein, large, P0 2.26836
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.24555
SPIDR scaffolding protein involved in DNA repair 2.24529
MXRA7 matrix-remodelling associated 7 2.23379
RPLP1 ribosomal protein, large, P1 2.20682
FAM161A family with sequence similarity 161, member A 2.19987
MSANTD7 Myb/SANT DNA binding domain containing 7 2.19477
GCN1 GCN1 activator of EIF2AK4 2.17444
MARCHF1 membrane associated ring-CH-type finger 1 2.16053
ERI2 ERI1 exoribonuclease family member 2 2.13926
SRD5A3 steroid 5 alpha-reductase 3 2.13916
MAP2K1 mitogen-activated protein kinase kinase 1 2.08035
DEPDC4 DEP domain containing 4 2.08035
CEP70 centrosomal protein 70kDa 2.05367
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted 2.04913
MMP17 matrix metallopeptidase 17 (membrane-inserted) 2.03725
SCYL2 SCY1-like 2 (S. cerevisiae) 2.03164
MARVELD2 MARVEL domain containing 2 2.03036
NAGA N-acetylgalactosaminidase, alpha- 2.02206
TIPE1 TNF alpha induced protein 8 like 1 2.02089
IL10RB interleukin 10 receptor, beta 2.00278

decreased expression

Symbol Name Standardized Value
TMEM160 transmembrane protein 160 -2.56784
HTRA3 HtrA serine peptidase 3 -2.56784
DLG2 discs, large homolog 2 (Drosophila) -2.56784
MBD5 methyl-CpG binding domain protein 5 -2.56784
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -2.56784
SPAG16 sperm associated antigen 16 -2.56784
ZNF322 zinc finger protein 322 -2.56784
DNAH5 dynein, axonemal, heavy chain 5 -2.56784
TP73 tumor protein p73 -2.56784
FAM111A family with sequence similarity 111, member A -2.56784
TRIM65 tripartite motif containing 65 -2.56784
C2ORF92 chromosome 2 open reading frame 92 -2.56784
GBA1 glucosylceramidase beta 1 -2.56784
POU2AF3 POU class 2 homeobox associating factor 3 -2.56784
SCN3B sodium channel, voltage gated, type III beta subunit -2.56784
DPEP1 dipeptidase 1 (renal) -2.56784
GLB1L galactosidase, beta 1-like -2.56784
DMAP1 DNA methyltransferase 1 associated protein 1 -2.56459
NHEJ1 nonhomologous end-joining factor 1 -2.52884
MYH11 myosin, heavy chain 11, smooth muscle -2.51107
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -2.46772
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.41516
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.35262
SNX21 sorting nexin family member 21 -2.33301
METTL24 methyltransferase like 24 -2.31749
LINC02560 long intergenic non-protein coding RNA 2560 -2.31749
ARSD arylsulfatase D -2.31749
LRRC56 leucine rich repeat containing 56 -2.31405
TTLL13 tubulin tyrosine ligase like 13 -2.31405
ALOX15 arachidonate 15-lipoxygenase -2.31405
WNT3A wingless-type MMTV integration site family, member 3A -2.31405
DNASE1L2 deoxyribonuclease I-like 2 -2.31405
IGFLR1 IGF-like family receptor 1 -2.31405
NANOS2 nanos homolog 2 (Drosophila) -2.31405
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -2.31405
H3C1 H3 clustered histone 1 -2.31405
DYNAP dynactin associated protein -2.31405
C6ORF118 chromosome 6 open reading frame 118 -2.31405
CFAP45 cilia and flagella associated protein 45 -2.31405
PDE1B phosphodiesterase 1B, calmodulin-dependent -2.31405
IRF4 interferon regulatory factor 4 -2.31405
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit -2.31405
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 -2.31405
SPINK9 serine peptidase inhibitor, Kazal type 9 -2.31405
ANGPTL3 angiopoietin-like 3 -2.31405
FRMPD1 FERM and PDZ domain containing 1 -2.31405
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -2.31405
SNTN sentan, cilia apical structure protein -2.31405
SDS serine dehydratase -2.31405
DRD4 dopamine receptor D4 -2.31405
STMND1 stathmin domain containing 1 -2.31405
IP6K3 inositol hexakisphosphate kinase 3 -2.31405
CLIC5 chloride intracellular channel 5 -2.31405
SCNN1D sodium channel, non voltage gated 1 delta subunit -2.31405
CD27 CD27 molecule -2.31405
HIGD1C HIG1 hypoxia inducible domain family, member 1C -2.31405
TNMD tenomodulin -2.31405
GFY golgi-associated, olfactory signaling regulator -2.31405
ASMT acetylserotonin O-methyltransferase -2.31405
CXORF58 chromosome X open reading frame 58 -2.31405
ZNF396 zinc finger protein 396 -2.31405
SV2C synaptic vesicle glycoprotein 2C -2.31405
ATG4A autophagy related 4A, cysteine peptidase -2.31405
LMNB1 lamin B1 -2.2996
ZNF713 zinc finger protein 713 -2.27527
CGRRF1 cell growth regulator with ring finger domain 1 -2.24986
BRICD5 BRICHOS domain containing 5 -2.23439
APOA1 apolipoprotein A-I -2.23439
C3ORF38 chromosome 3 open reading frame 38 -2.22981
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.19477
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -2.17474
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 -2.14268
COLEC12 collectin sub-family member 12 -2.13916
OR52A1 olfactory receptor, family 52, subfamily A, member 1 -2.1363
KRABD2 KRAB domain containing 2 -2.11726
POMT2 protein-O-mannosyltransferase 2 -2.09329
GREB1L growth regulation by estrogen in breast cancer-like -2.08462
PCYOX1 prenylcysteine oxidase 1 -2.07747
TMCO6 transmembrane and coiled-coil domains 6 -2.07582
ZNF587 zinc finger protein 587 -2.05962
APC adenomatous polyposis coli -2.05193
LINC02762 long intergenic non-protein coding RNA 2762 -2.03725
RAB27B RAB27B, member RAS oncogene family -2.03725
PLPPR5 phospholipid phosphatase related 5 -2.02484
EVA1C eva-1 homolog C (C. elegans) -2.0181
SCAMP4 secretory carrier membrane protein 4 -2.00329