TWIST2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description twist family bHLH transcription factor 2|The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 117581)
External Link http://www.ncbi.nlm.nih.gov/gene/117581
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Genes

5 interacting proteins for TWIST2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
MEF2C myocyte enhancer factor 2C
SREBF1 sterol regulatory element binding transcription factor 1
TP53 tumor protein p53
TWIST1 twist family bHLH transcription factor 1