| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | tyrosine kinase 2|This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7297) |
| External Link | https://ncbi.nlm.nih.gov/gene/7297 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the TYK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CSTA | cystatin A (stefin A) | 0.013807 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0122345 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.0118243 |
| KRT13 | keratin 13, type I | 0.0113111 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0109357 |
| MME | membrane metallo-endopeptidase | 0.0107931 |
| PRKCA | protein kinase C, alpha | 0.0106403 |
| S100A10 | S100 calcium binding protein A10 | 0.0105404 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.00991361 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00989461 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00939917 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00937717 |
| NKX3-1 | NK3 homeobox 1 | 0.00932048 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00928751 |
| KRT5 | keratin 5, type II | 0.00916838 |
| C7 | complement component 7 | 0.00898921 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00879567 |
| KRT19 | keratin 19, type I | 0.00866512 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00864851 |
| DEFB1 | defensin, beta 1 | 0.00858086 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00856889 |
| ANXA2 | annexin A2 | 0.00846194 |
| PDGFC | platelet derived growth factor C | 0.00843893 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00838107 |
| PERP | PERP, TP53 apoptosis effector | 0.00836166 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00811007 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00806899 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00804959 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00800927 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00799492 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00792782 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.00791879 |
| TPM2 | tropomyosin 2 (beta) | 0.00787289 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00776219 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00774929 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00771824 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.007704 |
| S100A2 | S100 calcium binding protein A2 | 0.00767928 |
| DSTN | destrin (actin depolymerizing factor) | 0.00760448 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00758181 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00757441 |
| RNF11 | ring finger protein 11 | 0.00756405 |
| SPRR3 | small proline-rich protein 3 | 0.00750376 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00748316 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00741528 |
| EMX2 | empty spiracles homeobox 2 | 0.00734373 |
| NEK7 | NIMA-related kinase 7 | 0.00723949 |
| SMAD6 | SMAD family member 6 | 0.00718642 |
| MSLN | mesothelin | 0.00717565 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00714038 |
| ADD3 | adducin 3 (gamma) | 0.00704948 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00703909 |
| KRT15 | keratin 15, type I | 0.00698209 |
| XPO7 | exportin 7 | 0.00697416 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00693895 |
| PDZK1 | PDZ domain containing 1 | 0.00693662 |
| KRT18 | keratin 18, type I | 0.00690806 |
| TMEM100 | transmembrane protein 100 | 0.00689874 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00688629 |
| CFI | complement factor I | 0.00687553 |
| CLIC3 | chloride intracellular channel 3 | 0.00678734 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00672808 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00671766 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00668505 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00668178 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00664194 |
| MAL | mal, T-cell differentiation protein | 0.0066269 |
| CD52 | CD52 molecule | 0.00661646 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.0066154 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00660609 |
| KYNU | kynureninase | 0.00660119 |
| AHNAK | AHNAK nucleoprotein | 0.00658896 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00658295 |
| COPS7A | COP9 signalosome subunit 7A | 0.00658079 |
| MEIS1 | Meis homeobox 1 | 0.00656332 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00652666 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00648418 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00647318 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00638931 |
| NELL1 | NEL-like 1 (chicken) | 0.00638727 |
| E2F2 | E2F transcription factor 2 | 0.00637851 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00637362 |
| CHEK1 | checkpoint kinase 1 | 0.0063678 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00635841 |
| PRNP | prion protein | 0.00634124 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0063357 |
| DACH1 | dachshund family transcription factor 1 | 0.00633079 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00629865 |
| LTA4H | leukotriene A4 hydrolase | 0.00624736 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00624633 |
| KRT17 | keratin 17, type I | 0.00624589 |
| DIAPH1 | diaphanous-related formin 1 | 0.00624448 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00618759 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.0061838 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00616315 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00610945 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00610141 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00608644 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00608038 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00605757 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00604684 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00603926 |
| RHOC | ras homolog family member C | 0.00599357 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00598634 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00598375 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00598246 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00594446 |
| ACP3 | acid phosphatase 3 | 0.00592944 |
| ATXN1 | ataxin 1 | 0.00591322 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00591294 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00589947 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00588416 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00588356 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00587677 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 | 0.00587297 |
| PTPRO | protein tyrosine phosphatase, receptor type, O | 0.00587061 |
| PODXL | podocalyxin-like | 0.00585839 |
| PAGE4 | P antigen family, member 4 (prostate associated) | 0.0058479 |
| DSP | desmoplakin | 0.00584611 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00583684 |
| SRP72 | signal recognition particle 72kDa | 0.00581139 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00580257 |
| HINT1 | histidine triad nucleotide binding protein 1 | 0.00573867 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00572144 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00570784 |
| YBX1 | Y box binding protein 1 | 0.0056979 |
| GNAS | GNAS complex locus | 0.00566274 |
| MECOM | MDS1 and EVI1 complex locus | 0.00558993 |
| ATP9A | ATPase, class II, type 9A | 0.00558109 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.00558008 |
| NELL2 | NEL-like 2 (chicken) | 0.00557504 |
| TMEM230 | transmembrane protein 230 | 0.0055631 |
| ODAM | odontogenic, ameloblast asssociated | 0.00556014 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00555618 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0055549 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00553742 |
| KRT6A | keratin 6A, type II | 0.00553305 |
| KRT14 | keratin 14, type I | 0.00553193 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00553168 |
| TYMS | thymidylate synthetase | 0.00552483 |
| MYOF | myoferlin | 0.00552082 |
| AIM2 | absent in melanoma 2 | 0.005494 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00547672 |
| TSPAN8 | tetraspanin 8 | 0.00546667 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | 0.00546059 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00544015 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00543272 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00541605 |
| MUC16 | mucin 16, cell surface associated | 0.0054061 |
| EXT1 | exostosin glycosyltransferase 1 | 0.005404 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00540024 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00539504 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00538978 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.0053773 |
| CCDC85B | coiled-coil domain containing 85B | 0.00537423 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0053718 |
| ERLIN1 | ER lipid raft associated 1 | 0.00537167 |
| PITX1 | paired-like homeodomain 1 | 0.00537067 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00536835 |
| CD99 | CD99 molecule | 0.00535661 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00534353 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00532642 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00530916 |
| RPL14 | ribosomal protein L14 | 0.00529994 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00529896 |
| ADIPOR1 | adiponectin receptor 1 | 0.00528686 |
| C1RL | complement component 1, r subcomponent-like | 0.00528206 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00526466 |
| MGMT | O-6-methylguanine-DNA methyltransferase | 0.00525891 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00525664 |
| CLIC5 | chloride intracellular channel 5 | 0.00525234 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00524877 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00521644 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00521351 |
| CLCA2 | chloride channel accessory 2 | 0.0052132 |
| PCLAF | PCNA clamp associated factor | 0.00521151 |
| PCNA | proliferating cell nuclear antigen | 0.00519921 |
| DCTN3 | dynactin 3 (p22) | 0.00519464 |
| ALB | albumin | 0.00519038 |
| SET | SET nuclear proto-oncogene | 0.00518857 |
| RANBP9 | RAN binding protein 9 | 0.00518674 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00518189 |
| S100A7 | S100 calcium binding protein A7 | 0.00516345 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.00515396 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.00514856 |
| SFN | stratifin | 0.0051429 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00514169 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00511653 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00511228 |
| STON1 | stonin 1 | 0.00510828 |
| CDC123 | cell division cycle 123 | 0.00510743 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00509307 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.00507555 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.00506473 |
| IFI44 | interferon-induced protein 44 | 0.00506005 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00501659 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00501427 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00499685 |
| SVIL | supervillin | 0.00499443 |
| SORD | sorbitol dehydrogenase | 0.00499388 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00499241 |
| CA9 | carbonic anhydrase IX | 0.00497587 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00496151 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0049564 |
| ENO1 | enolase 1, (alpha) | 0.00494481 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00493988 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00493664 |
| RGS10 | regulator of G-protein signaling 10 | 0.00493452 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | 0.00491452 |
| KLK3 | kallikrein-related peptidase 3 | 0.00490959 |
| YBX3 | Y box binding protein 3 | 0.00490536 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00489465 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0048934 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00488753 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00488612 |
| PNOC | prepronociceptin | 0.00488307 |
| IL10RB | interleukin 10 receptor, beta | 0.00487566 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00487447 |
| TCAF1 | TRPM8 channel-associated factor 1 | 0.0048657 |
| PPID | peptidylprolyl isomerase D | 0.00486505 |
| MMP7 | matrix metallopeptidase 7 | 0.00486221 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.00485952 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00485174 |
| OXTR | oxytocin receptor | 0.00484844 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00484538 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00484169 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00483921 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00483873 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.00483462 |
| SLC38A4 | solute carrier family 38, member 4 | 0.00482715 |
| SSR4 | signal sequence receptor, delta | 0.0048082 |
| MRTFB | myocardin related transcription factor B | 0.00480396 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00479491 |
| RBBP7 | retinoblastoma binding protein 7 | 0.00476764 |
| IFNGR1 | interferon gamma receptor 1 | 0.0047657 |
| CTSB | cathepsin B | 0.00476518 |
| SERINC5 | serine incorporator 5 | 0.00476489 |
| ASB9 | ankyrin repeat and SOCS box containing 9 | 0.00476315 |
| HEATR1 | HEAT repeat containing 1 | 0.00475084 |
| TSPAN13 | tetraspanin 13 | 0.00474773 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 0.00474494 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00474452 |
| SMAGP | small cell adhesion glycoprotein | 0.00474003 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00472334 |
| AHR | aryl hydrocarbon receptor | 0.00472017 |
| SELL | selectin L | 0.00470293 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00470233 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00468503 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 | 0.00467945 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 0.00467552 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDGFRL | platelet-derived growth factor receptor-like | -0.0119396 |
| NID2 | nidogen 2 (osteonidogen) | -0.0109593 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0109565 |
| ASPN | asporin | -0.0108203 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00986585 |
| CD320 | CD320 molecule | -0.00971398 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00970602 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00959259 |
| RGS16 | regulator of G-protein signaling 16 | -0.00945753 |
| LTF | lactotransferrin | -0.00884423 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00883818 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00872782 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00871427 |
| SLC46A3 | solute carrier family 46, member 3 | -0.00869971 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00862875 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.008565 |
| CADM1 | cell adhesion molecule 1 | -0.00845847 |
| RTN2 | reticulon 2 | -0.00844709 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00838498 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00809618 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00805938 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00786064 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00775337 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.00765138 |
| CDC20 | cell division cycle 20 | -0.00763992 |
| STK10 | serine/threonine kinase 10 | -0.00763159 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00762055 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00750422 |
| TPCN1 | two pore segment channel 1 | -0.00750084 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00749796 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00744208 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0074361 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00739734 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00735529 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00735064 |
| DLD | dihydrolipoamide dehydrogenase | -0.00726488 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00720277 |
| MGLL | monoglyceride lipase | -0.00713374 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00711803 |
| MICU2 | mitochondrial calcium uptake 2 | -0.00710452 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00703823 |
| GAS7 | growth arrest-specific 7 | -0.0070374 |
| SHOX2 | short stature homeobox 2 | -0.00703144 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00701855 |
| OLFML2B | olfactomedin-like 2B | -0.00694497 |
| TSPAN4 | tetraspanin 4 | -0.00691479 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00690069 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00689959 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00686199 |
| TPD52 | tumor protein D52 | -0.00685048 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00684992 |
| TMEM176A | transmembrane protein 176A | -0.00683607 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00682049 |
| RNF167 | ring finger protein 167 | -0.00681814 |
| TMEM176B | transmembrane protein 176B | -0.00680643 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00679698 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00679032 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.00678841 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00676063 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00671502 |
| SGCE | sarcoglycan, epsilon | -0.00670379 |
| G0S2 | G0/G1 switch 2 | -0.00667184 |
| MAP7 | microtubule-associated protein 7 | -0.00661137 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00658223 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.0065599 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00655086 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | -0.00651962 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.0064302 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.00639876 |
| IL6 | interleukin 6 | -0.00639344 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00639035 |
| UPP1 | uridine phosphorylase 1 | -0.00635517 |
| CD209 | CD209 molecule | -0.00633916 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | -0.0063139 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00629546 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.00624071 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00623357 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00620964 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00620884 |
| ZIC1 | Zic family member 1 | -0.0061841 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | -0.00618159 |
| POSTN | periostin, osteoblast specific factor | -0.00615944 |
| AEBP1 | AE binding protein 1 | -0.00615907 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | -0.00615111 |
| XYLT1 | xylosyltransferase I | -0.00614912 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.00612643 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00611972 |
| CTSZ | cathepsin Z | -0.00611413 |
| GOLGA8H | golgin A8 family, member H | -0.006086 |
| ANK2 | ankyrin 2, neuronal | -0.00606821 |
| MFAP5 | microfibrillar associated protein 5 | -0.00598019 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00597494 |
| MT1M | metallothionein 1M | -0.00596337 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00592171 |
| COL5A2 | collagen, type V, alpha 2 | -0.00591578 |
| RAPSN | receptor-associated protein of the synapse | -0.00590431 |
| TUBA4A | tubulin, alpha 4a | -0.00590155 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00589369 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | -0.00589353 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00586351 |
| PPIF | peptidylprolyl isomerase F | -0.00585543 |
| PROM1 | prominin 1 | -0.00585229 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.0058275 |
| CD163 | CD163 molecule | -0.0058155 |
| SCAMP4 | secretory carrier membrane protein 4 | -0.005811 |
| UBL3 | ubiquitin-like 3 | -0.00580225 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00577016 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0057612 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | -0.00576115 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.00574094 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00573543 |
| ING3 | inhibitor of growth family, member 3 | -0.0057135 |
| RBPMS | RNA binding protein with multiple splicing | -0.00570851 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00570757 |
| MCM7 | minichromosome maintenance complex component 7 | -0.00568895 |
| EREG | epiregulin | -0.00568734 |
| CD83 | CD83 molecule | -0.00567917 |
| EXPH5 | exophilin 5 | -0.00567478 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00566408 |
| CD38 | CD38 molecule | -0.00564642 |
| TG | thyroglobulin | -0.00564498 |
| ZFAND1 | zinc finger, AN1-type domain 1 | -0.00561301 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00557602 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00555831 |
| H2AX | H2A.X variant histone | -0.00555292 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00553556 |
| ASPH | aspartate beta-hydroxylase | -0.00552578 |
| BRD4 | bromodomain containing 4 | -0.00551659 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00551459 |
| CLCN7 | chloride channel, voltage-sensitive 7 | -0.00551151 |
| PRPF3 | pre-mRNA processing factor 3 | -0.00549702 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00549672 |
| PLS3 | plastin 3 | -0.00547734 |
| LOC283683 | uncharacterized LOC283683 | -0.00547493 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00546898 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00546885 |
| TSPO | translocator protein (18kDa) | -0.00545976 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | -0.00545785 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.00544713 |
| PCDH17 | protocadherin 17 | -0.00540154 |
| ZG16 | zymogen granule protein 16 | -0.00540138 |
| DNAAF1 | dynein, axonemal, assembly factor 1 | -0.00539101 |
| SAFB2 | scaffold attachment factor B2 | -0.00538731 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0053637 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00535134 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00534844 |
| NEFM | neurofilament, medium polypeptide | -0.00533971 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00533728 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00533224 |
| ITPKB | inositol-trisphosphate 3-kinase B | -0.00532425 |
| AMPD3 | adenosine monophosphate deaminase 3 | -0.005317 |
| BNC2 | basonuclin 2 | -0.00531206 |
| NIT1 | nitrilase 1 | -0.00530769 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00530718 |
| SC5D | sterol-C5-desaturase | -0.0052979 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00529608 |
| S100B | S100 calcium binding protein B | -0.00529253 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00528783 |
| TSPYL5 | TSPY-like 5 | -0.0052699 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00526343 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00526306 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00525376 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00525059 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00524877 |
| BOP1 | block of proliferation 1 | -0.00524281 |
| DBF4 | DBF4 zinc finger | -0.00524103 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00523297 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00522891 |
| CA4 | carbonic anhydrase IV | -0.00522791 |
| C2 | complement component 2 | -0.00522781 |
| ARHGAP33 | Rho GTPase activating protein 33 | -0.00522722 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | -0.00520823 |
| GAL | galanin/GMAP prepropeptide | -0.00520158 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0051841 |
| BEX1 | brain expressed, X-linked 1 | -0.00517941 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00516518 |
| GPM6B | glycoprotein M6B | -0.00515392 |
| FBN2 | fibrillin 2 | -0.00511823 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0050942 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00509403 |
| DCLK1 | doublecortin-like kinase 1 | -0.00507925 |
| KLF9 | Kruppel-like factor 9 | -0.00506838 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00506542 |
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | -0.00506245 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 | -0.00506182 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | -0.00504173 |
| CTSL | cathepsin L | -0.00502966 |
| CCL13 | chemokine (C-C motif) ligand 13 | -0.0050089 |
| FADS3 | fatty acid desaturase 3 | -0.00499745 |
| MMP11 | matrix metallopeptidase 11 | -0.00499677 |
| RRAGD | Ras-related GTP binding D | -0.00497935 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.00497812 |
| SDC2 | syndecan 2 | -0.00497101 |
| H1-0 | H1.0 linker histone | -0.00496463 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00496147 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -0.00495898 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00495761 |
| GSE1 | Gse1 coiled-coil protein | -0.00493339 |
| CHGB | chromogranin B | -0.00492586 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | -0.00492525 |
| LYPLA1 | lysophospholipase I | -0.00492381 |
| FBLN1 | fibulin 1 | -0.00492073 |
| ABHD17A | abhydrolase domain containing 17A | -0.00491827 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00491126 |
| LXN | latexin | -0.00490921 |
| POLRMT | polymerase (RNA) mitochondrial (DNA directed) | -0.00489769 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00489038 |
| ACO2 | aconitase 2, mitochondrial | -0.00488768 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00488524 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | -0.0048806 |
| NAV2 | neuron navigator 2 | -0.00488055 |
| COL5A3 | collagen, type V, alpha 3 | -0.00487565 |
| BMP2 | bone morphogenetic protein 2 | -0.00486581 |
| ADCY9 | adenylate cyclase 9 | -0.00486471 |
| TNMD | tenomodulin | -0.00486422 |
| MCOLN1 | mucolipin 1 | -0.00484943 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.00482789 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00482626 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | -0.00481911 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00481738 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | -0.00480757 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00479455 |
| TRRAP | transformation/transcription domain-associated protein | -0.00478968 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00478673 |
| CEL | carboxyl ester lipase | -0.00478229 |
| FOLR2 | folate receptor 2 (fetal) | -0.00478203 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00478032 |
| RNF19B | ring finger protein 19B | -0.00476936 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00476754 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00475719 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00475355 |
| PLXNC1 | plexin C1 | -0.00474899 |
| WTAP | Wilms tumor 1 associated protein | -0.0047483 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00474359 |
| CNN3 | calponin 3, acidic | -0.00473942 |
| FCGBP | Fc fragment of IgG binding protein | -0.00473927 |
| AK1 | adenylate kinase 1 | -0.00473081 |
| FOXN3 | forkhead box N3 | -0.00472351 |
| USP47 | ubiquitin specific peptidase 47 | -0.00470561 |
| PIR | pirin (iron-binding nuclear protein) | -0.00469293 |
| GPX4 | glutathione peroxidase 4 | -0.00468086 |
| NRCAM | neuronal cell adhesion molecule | -0.00468038 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00467132 |
| GUSB | glucuronidase, beta | -0.00466829 |
| TSPAN9 | tetraspanin 9 | -0.00465863 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00465275 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00465162 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00464766 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00463376 |
| NAV3 | neuron navigator 3 | -0.00461159 |
