TYR Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description tyrosinase|The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 7299)
External Link http://www.ncbi.nlm.nih.gov/gene/7299
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Genes

5 interacting proteins for TYR from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
DCT dopachrome tautomerase
PRKCB protein kinase C, beta
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TYRP1 tyrosinase-related protein 1
UBC ubiquitin C