| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | TYRO protein tyrosine kinase binding protein|This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010] (NCBI Entrez Gene Database, 7305) |
| External Link | https://ncbi.nlm.nih.gov/gene/7305 |
| Similar Terms | |
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497 genes differentially expressed following the TYROBP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0185647 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.015552 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0140829 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0128333 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 0.0115711 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0113752 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.0110397 |
| PTK2 | protein tyrosine kinase 2 | 0.0104177 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0103646 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.0102687 |
| FAM3C | family with sequence similarity 3, member C | 0.00994235 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00978301 |
| CYC1 | cytochrome c-1 | 0.00962948 |
| PCP4 | Purkinje cell protein 4 | 0.00960479 |
| CNN3 | calponin 3, acidic | 0.00954761 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00951909 |
| RPS5 | ribosomal protein S5 | 0.00933915 |
| YBX3 | Y box binding protein 3 | 0.00920275 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00910506 |
| EREG | epiregulin | 0.00908646 |
| GPR183 | G protein-coupled receptor 183 | 0.00898656 |
| CHKB | choline kinase beta | 0.00898612 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00896062 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00895737 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0088721 |
| GLO1 | glyoxalase I | 0.00880742 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0087483 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00874103 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | 0.00873729 |
| BCHE | butyrylcholinesterase | 0.00861925 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.00859276 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00855858 |
| TRMT5 | tRNA methyltransferase 5 | 0.00854146 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00850275 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00845372 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00828495 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0080211 |
| TMC5 | transmembrane channel-like 5 | 0.0080173 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00799415 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00798466 |
| TUBA1A | tubulin, alpha 1a | 0.00795799 |
| CNTNAP2 | contactin associated protein-like 2 | 0.00794742 |
| KRT2 | keratin 2, type II | 0.00790695 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00787771 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00777493 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00774509 |
| PTN | pleiotrophin | 0.00772827 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00771011 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00769919 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00767615 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00766377 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00764886 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00763486 |
| HOXB2 | homeobox B2 | 0.00756011 |
| CS | citrate synthase | 0.00753551 |
| ACP3 | acid phosphatase 3 | 0.00753145 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00752045 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.00747036 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00746732 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | 0.00741579 |
| FLOT1 | flotillin 1 | 0.00738149 |
| RANBP1 | RAN binding protein 1 | 0.00734416 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00732499 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00729916 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.00728694 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00725018 |
| TMEM231 | transmembrane protein 231 | 0.00721954 |
| HNMT | histamine N-methyltransferase | 0.00720329 |
| ODC1 | ornithine decarboxylase 1 | 0.00720173 |
| ACP6 | acid phosphatase 6, lysophosphatidic | 0.00719369 |
| H2AX | H2A.X variant histone | 0.00717412 |
| YME1L1 | YME1-like 1 ATPase | 0.00716993 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00716444 |
| RLN1 | relaxin 1 | 0.00715316 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00714471 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00712722 |
| RAB27A | RAB27A, member RAS oncogene family | 0.00708807 |
| HMGB1 | high mobility group box 1 | 0.00708491 |
| TSPAN7 | tetraspanin 7 | 0.00708211 |
| RPL29 | ribosomal protein L29 | 0.00707975 |
| PGC | progastricsin (pepsinogen C) | 0.00706431 |
| S100A2 | S100 calcium binding protein A2 | 0.00702359 |
| PGAP3 | post-GPI attachment to proteins 3 | 0.00702319 |
| GSAP | gamma-secretase activating protein | 0.00699698 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.006973 |
| CBX6 | chromobox homolog 6 | 0.00693423 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00690966 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00689589 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00688004 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.00686677 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00685597 |
| TENM1 | teneurin transmembrane protein 1 | 0.00684963 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00682676 |
| IDE | insulin-degrading enzyme | 0.00681108 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00679329 |
| PCGF2 | polycomb group ring finger 2 | 0.0067618 |
| RPL10A | ribosomal protein L10a | 0.00675782 |
| GLB1L2 | galactosidase, beta 1-like 2 | 0.00675122 |
| ASRGL1 | asparaginase like 1 | 0.00674119 |
| KRT1 | keratin 1, type II | 0.00673512 |
| CCNA2 | cyclin A2 | 0.00673152 |
| NES | nestin | 0.00671143 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00669125 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 0.00668497 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.00668191 |
| MIPEP | mitochondrial intermediate peptidase | 0.00667401 |
| EMX2 | empty spiracles homeobox 2 | 0.00667353 |
| SPART | spartin | 0.00667108 |
| PFN2 | profilin 2 | 0.00665088 |
| FASN | fatty acid synthase | 0.00661472 |
| ACTL6A | actin-like 6A | 0.00661333 |
| HAL | histidine ammonia-lyase | 0.00660356 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00660157 |
| SLC2A4RG | SLC2A4 regulator | 0.00659848 |
| PLN | phospholamban | 0.00657702 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.0065633 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00655491 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.00654222 |
| KLHDC3 | kelch domain containing 3 | 0.00653727 |
| ADK | adenosine kinase | 0.00653579 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00651531 |
| RAPSN | receptor-associated protein of the synapse | 0.00651518 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.00650759 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00649533 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.00649085 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00648406 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00645304 |
| KIAA0226L | KIAA0226-like | 0.00643541 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00643459 |
| DES | desmin | 0.00641893 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00640836 |
| CTSH | cathepsin H | 0.00640669 |
| FTO | fat mass and obesity associated | 0.00640566 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00639701 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | 0.00639504 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00638442 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | 0.00638149 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.00635943 |
| ENO1 | enolase 1, (alpha) | 0.00635641 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00634077 |
| UBL3 | ubiquitin-like 3 | 0.00632637 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0063261 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | 0.00632236 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.00631661 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | 0.00631411 |
| HMGB2 | high mobility group box 2 | 0.00630744 |
| CBY1 | chibby homolog 1 (Drosophila) | 0.00629946 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 0.00629662 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 | 0.00629544 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0062819 |
| PHB2 | prohibitin 2 | 0.00628074 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00627879 |
| DPT | dermatopontin | 0.00627629 |
| KCTD14 | potassium channel tetramerization domain containing 14 | 0.00627484 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.00627216 |
| REG3A | regenerating islet-derived 3 alpha | 0.0062634 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00626052 |
| CD99 | CD99 molecule | 0.00625965 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00625653 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00623991 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.0062217 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | 0.00619624 |
| OVGP1 | oviductal glycoprotein 1, 120kDa | 0.00618571 |
| ATP11B | ATPase, class VI, type 11B | 0.00618564 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | 0.00617551 |
| SGMS1 | sphingomyelin synthase 1 | 0.0061604 |
| DSC1 | desmocollin 1 | 0.00612677 |
| DCLK1 | doublecortin-like kinase 1 | 0.00610518 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00607928 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00606114 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00604191 |
| STK38L | serine/threonine kinase 38 like | 0.00602029 |
| SRSF7 | serine/arginine-rich splicing factor 7 | 0.00601334 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00600989 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | 0.006008 |
| POSTN | periostin, osteoblast specific factor | 0.00600481 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00599907 |
| CD200 | CD200 molecule | 0.00599775 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00599587 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00598222 |
| ADSL | adenylosuccinate lyase | 0.00597514 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00597329 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00596485 |
| ESD | esterase D | 0.00596227 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00595444 |
| FRY | furry homolog (Drosophila) | 0.00594512 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.00591359 |
| AQP9 | aquaporin 9 | 0.00590461 |
| ANGEL2 | angel homolog 2 (Drosophila) | 0.00589886 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00588796 |
| ACTB | actin, beta | 0.00584963 |
| PFKL | phosphofructokinase, liver | 0.00584824 |
| SRP9 | signal recognition particle 9kDa | 0.00584322 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00584207 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | 0.00583568 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.0058173 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00581332 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00580728 |
| SUCLG1 | succinate-CoA ligase, alpha subunit | 0.00577357 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00577258 |
| TMEM254 | transmembrane protein 254 | 0.00576474 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.00576253 |
| CCND2 | cyclin D2 | 0.00575902 |
| MED22 | mediator complex subunit 22 | 0.00575514 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.00574794 |
| ILF2 | interleukin enhancer binding factor 2 | 0.00574485 |
| CST3 | cystatin C | 0.00573998 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.00573264 |
| BOP1 | block of proliferation 1 | 0.00572809 |
| LOR | loricrin | 0.00572709 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00572371 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.00571958 |
| PRDX2 | peroxiredoxin 2 | 0.00571076 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00569697 |
| TNC | tenascin C | 0.0056969 |
| KIF1B | kinesin family member 1B | 0.00568923 |
| SNU13 | small nuclear ribonucleoprotein 13 | 0.00568603 |
| DEK | DEK proto-oncogene | 0.00565303 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00565202 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00563696 |
| FZD5 | frizzled class receptor 5 | 0.00563202 |
| OAT | ornithine aminotransferase | 0.00562728 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00561778 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I | 0.00560805 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00560677 |
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.00560176 |
| WDR7 | WD repeat domain 7 | 0.00558726 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.00558175 |
| SETMAR | SET domain and mariner transposase fusion gene | 0.00557653 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00557604 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00556766 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00555944 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00554281 |
| COL21A1 | collagen, type XXI, alpha 1 | 0.00553838 |
| CDSN | corneodesmosin | 0.00553195 |
| RORA | RAR-related orphan receptor A | 0.00552508 |
| RPN2 | ribophorin II | 0.00552167 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00551926 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.00551893 |
| THAP12 | THAP domain containing 12 | 0.00551705 |
| KLK2 | kallikrein-related peptidase 2 | 0.00550649 |
| A2M | alpha-2-macroglobulin | 0.00549518 |
| KIF20A | kinesin family member 20A | 0.00548275 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00547172 |
| ACACA | acetyl-CoA carboxylase alpha | 0.00546565 |
| KRT5 | keratin 5, type II | 0.00546548 |
| BCS1L | BC1 (ubiquinol-cytochrome c reductase) synthesis-like | 0.00546007 |
| LCE2B | late cornified envelope 2B | 0.00544755 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.00544343 |
| Symbol | Name | Standardized Value |
|---|---|---|
| S100P | S100 calcium binding protein P | -0.0204485 |
| RBM34 | RNA binding motif protein 34 | -0.0179041 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0161197 |
| MAP7 | microtubule-associated protein 7 | -0.0156179 |
| JMJD6 | jumonji domain containing 6 | -0.014983 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0149456 |
| MGLL | monoglyceride lipase | -0.0146823 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.014667 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0144636 |
| MAGEA3 | melanoma antigen family A3 | -0.0143782 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0139352 |
| GLOD4 | glyoxalase domain containing 4 | -0.0136535 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0130171 |
| TSPAN13 | tetraspanin 13 | -0.0127744 |
| PXDN | peroxidasin | -0.0120817 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0119975 |
| ASS1 | argininosuccinate synthase 1 | -0.0119257 |
| TPD52L1 | tumor protein D52-like 1 | -0.011881 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.011311 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0111662 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0111329 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.0110946 |
| SIK1 | salt-inducible kinase 1 | -0.0108201 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.0108194 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0107124 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0106789 |
| RPS27L | ribosomal protein S27-like | -0.0106635 |
| CA12 | carbonic anhydrase XII | -0.0105532 |
| CTSD | cathepsin D | -0.010551 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0105306 |
| ECM1 | extracellular matrix protein 1 | -0.0105136 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0104951 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.0104736 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0104626 |
| RND3 | Rho family GTPase 3 | -0.0103418 |
| HOXC6 | homeobox C6 | -0.0102706 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0102064 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0101975 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0100894 |
| HTRA1 | HtrA serine peptidase 1 | -0.0100789 |
| MIR22HG | MIR22 host gene | -0.0100348 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0099322 |
| LY96 | lymphocyte antigen 96 | -0.00993184 |
| CLIC5 | chloride intracellular channel 5 | -0.00991471 |
| MT1X | metallothionein 1X | -0.00987807 |
| TFF1 | trefoil factor 1 | -0.00980478 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00967261 |
| ADM | adrenomedullin | -0.00963826 |
| RHOF | ras homolog family member F (in filopodia) | -0.00961284 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00958711 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.009526 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00950302 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00947378 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00941702 |
| STC2 | stanniocalcin 2 | -0.00930366 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00926381 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00920246 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00914438 |
| CDV3 | CDV3 homolog (mouse) | -0.00913759 |
| HK2 | hexokinase 2 | -0.00912978 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.00912969 |
| ADCY9 | adenylate cyclase 9 | -0.00910333 |
| ADIRF | adipogenesis regulatory factor | -0.00904681 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00904407 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00896379 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00896218 |
| THBS2 | thrombospondin 2 | -0.00895912 |
| GOLGA8A | golgin A8 family, member A | -0.00892264 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00890045 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00889334 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00885896 |
| DUSP5 | dual specificity phosphatase 5 | -0.0088582 |
| LAMB1 | laminin, beta 1 | -0.00877117 |
| G0S2 | G0/G1 switch 2 | -0.00877015 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00869584 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.00869138 |
| KRT7 | keratin 7, type II | -0.00863384 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00861848 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00861658 |
| RAB8A | RAB8A, member RAS oncogene family | -0.00860502 |
| CORO1C | coronin, actin binding protein, 1C | -0.00858732 |
| HMOX1 | heme oxygenase 1 | -0.0085709 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00855934 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00845641 |
| ABLIM1 | actin binding LIM protein 1 | -0.0083975 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00839368 |
| NNMT | nicotinamide N-methyltransferase | -0.00837155 |
| IER5 | immediate early response 5 | -0.0083587 |
| CST1 | cystatin SN | -0.00832972 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00832515 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00832165 |
| FN1 | fibronectin 1 | -0.00831817 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00830097 |
| NID2 | nidogen 2 (osteonidogen) | -0.00827914 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00825816 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.00823289 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00817857 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00817077 |
| ATP9A | ATPase, class II, type 9A | -0.00816684 |
| CCND3 | cyclin D3 | -0.00812127 |
| PLXNC1 | plexin C1 | -0.0081134 |
| MFSD1 | major facilitator superfamily domain containing 1 | -0.00803238 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00802398 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00800345 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00799441 |
| NDNF | neuron-derived neurotrophic factor | -0.00797716 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00797511 |
| PALLD | palladin, cytoskeletal associated protein | -0.00792951 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00792657 |
| MX1 | MX dynamin-like GTPase 1 | -0.00792501 |
| CDA | cytidine deaminase | -0.00789954 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00787542 |
| RGS1 | regulator of G-protein signaling 1 | -0.0078682 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00785077 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00784912 |
| GCH1 | GTP cyclohydrolase 1 | -0.00783047 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00780251 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.0077854 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00776192 |
| BICC1 | BicC family RNA binding protein 1 | -0.00775409 |
| INHBA | inhibin, beta A | -0.00775211 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00773388 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00772517 |
| LXN | latexin | -0.00770468 |
| MALL | mal, T-cell differentiation protein-like | -0.00768777 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00767625 |
| CRYAB | crystallin, alpha B | -0.00766537 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00764501 |
| DCN | decorin | -0.00763022 |
| HECA | headcase homolog (Drosophila) | -0.00759315 |
| SNAI2 | snail family zinc finger 2 | -0.00758081 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00757985 |
| ARMT1 | acidic residue methyltransferase 1 | -0.00756436 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00752342 |
| RRAGC | Ras-related GTP binding C | -0.00749356 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00749014 |
| OPTN | optineurin | -0.00748092 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -0.00745959 |
| KLF10 | Kruppel-like factor 10 | -0.0074554 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | -0.0074416 |
| MT2A | metallothionein 2A | -0.00743462 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.00743309 |
| KIAA0355 | KIAA0355 | -0.00743178 |
| RRAGD | Ras-related GTP binding D | -0.00739615 |
| MT1H | metallothionein 1H | -0.00736842 |
| JUP | junction plakoglobin | -0.00736825 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.00736385 |
| CTSA | cathepsin A | -0.00735295 |
| RHOD | ras homolog family member D | -0.00734918 |
| IFI44 | interferon-induced protein 44 | -0.00734083 |
| FHL2 | four and a half LIM domains 2 | -0.00732067 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -0.00731405 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.00730596 |
| IL1B | interleukin 1, beta | -0.00729955 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00727988 |
| S100A11 | S100 calcium binding protein A11 | -0.00727459 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00719511 |
| TUFT1 | tuftelin 1 | -0.00719191 |
| GRN | granulin | -0.00714917 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.00714405 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00714303 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00713175 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00712334 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00711524 |
| PLK2 | polo-like kinase 2 | -0.00709274 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.0070756 |
| SPRR3 | small proline-rich protein 3 | -0.00707454 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00706261 |
| RTCA | RNA 3'-terminal phosphate cyclase | -0.00705998 |
| CCN2 | cellular communication network factor 2 | -0.00705793 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00703046 |
| EPHA2 | EPH receptor A2 | -0.00703035 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | -0.00701547 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00700264 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00699351 |
| MAGEA1 | melanoma antigen family A1 | -0.00697663 |
| BGN | biglycan | -0.00697527 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00697341 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00694503 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00694447 |
| MAGEA12 | melanoma antigen family A12 | -0.00694249 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00693383 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00692999 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00692688 |
| MVP | major vault protein | -0.00690013 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.00689584 |
| BMP2 | bone morphogenetic protein 2 | -0.00689141 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.0068821 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00687826 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0068515 |
| TFRC | transferrin receptor | -0.00682744 |
| MCL1 | myeloid cell leukemia 1 | -0.00682422 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00681175 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00678691 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00678601 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00677984 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00675932 |
| MRPL34 | mitochondrial ribosomal protein L34 | -0.00675613 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00673113 |
| PRR13 | proline rich 13 | -0.00671907 |
| RET | ret proto-oncogene | -0.0066972 |
| IL2RG | interleukin 2 receptor, gamma | -0.00669037 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00668708 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00667239 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00666733 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00666494 |
| CTTN | cortactin | -0.00663959 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.00662964 |
| AMOTL2 | angiomotin like 2 | -0.00662377 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.006611 |
| HOPX | HOP homeobox | -0.00659925 |
| DSG3 | desmoglein 3 | -0.0065983 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00659376 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00658411 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00658395 |
| RUNX1 | runt-related transcription factor 1 | -0.00657985 |
| FOXD1 | forkhead box D1 | -0.00657798 |
| KRT8 | keratin 8, type II | -0.00657767 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00655903 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00654518 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | -0.0065375 |
| CTSE | cathepsin E | -0.00652464 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00652055 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00651056 |
| GMFG | glia maturation factor, gamma | -0.00649356 |
| SMAD3 | SMAD family member 3 | -0.00648649 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00645493 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00645442 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00644882 |
| FAM102A | family with sequence similarity 102, member A | -0.00644791 |
| MTF2 | metal response element binding transcription factor 2 | -0.00644184 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00643246 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00642094 |
| ZNF281 | zinc finger protein 281 | -0.00640098 |
| LCN2 | lipocalin 2 | -0.00639983 |
| EHD3 | EH-domain containing 3 | -0.0063754 |
| SLC16A4 | solute carrier family 16, member 4 | -0.00637505 |
| EVI2A | ecotropic viral integration site 2A | -0.00635779 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.00634067 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00633876 |
| SP110 | SP110 nuclear body protein | -0.00633252 |
| IL6ST | interleukin 6 signal transducer | -0.00633213 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.006299 |
| CTSZ | cathepsin Z | -0.00629886 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.00629728 |
| MMD | monocyte to macrophage differentiation-associated | -0.00629658 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.00628678 |
| SSH3 | slingshot protein phosphatase 3 | -0.00625906 |
